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TRACE ELEMENT

  • Jef Marc Valencia

    • 問題数 79 • 7/10/2025

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  • 1

    Appear in small quantity associated with enzyme or proteins which deficiency impairs a biochemical or functional process: replacement corrects the impairment

    TRACE ELEMENT

  • 2

    Specimen of choice for trace elements

    ANTI COAGULATED BLOOD

  • 3

    Characteristics of trace elements

    LOW CONCENTRATION, UBIQUITOUS

  • 4

    Method of choice for trace elements

    AAS

  • 5

    3RD most abundant trace elements important for cellular respiration, DNA and RNA reproduction, cell membrane integrity, sequestration of free radicals

    COPPER

  • 6

    Dietary requirement for copper

    1.5-3.0 MG/DAY

  • 7

    Highest copper concnetration

    LIVER

  • 8

    A-2 globulin copper containing protein

    CERULOPLASMIN

  • 9

    What enzyme found in ceruloplasmin

    FERROXIDASE

  • 10

    Ceruloplasmin contains copper but not___protein since the copper is not exchangeable

    TRANSPORT

  • 11

    Albumin bound which transports copper

    TRANSCUPERIN

  • 12

    Albumin boundd which sequesters and stores copper

    METALLOTHIONEIN

  • 13

    Copper deficiency is seen in

    PREMATURE INFANT, OSTEOPOROSIS, CVD, MENKES DISEASE

  • 14

    Aside from kinky hair, this is also seen in menkes disease

    HYPOTONIA

  • 15

    Refers to increased tissue and serum level of copper

    COPPER TOXICITY

  • 16

    Acute copper poisoning is c'monly caused by

    FUNGICIDE

  • 17

    Genetically determined copper accumulation disease

    WILSONS DISEASE

  • 18

    In Wilsons disease, copper accumulates in what tissues

    LIVER, BRAIN, CORNEA

  • 19

    Manifestations of wilsons disease

    NEUROLOGIC DISORDER, LIVER DYSFUNCTION

  • 20

    Green brown discoloration in the cornea due to wilsons disease

    KAYSER FLEISCHER RING

  • 21

    Serum or urine copper is measured via

    AAS, COLORIMETRIC METHOD

  • 22

    Ceruloplasmin is measured via

    PHOTOMETRIC METHOD, NEPHELOMETRY

  • 23

    Method of choice for copper

    AAS

  • 24

    Immunological method determination for copper

    NEPHELOMETRY

  • 25

    Reference value for copper male

    70-140 UG/DL, 11-22 UMOL/L

  • 26

    Reference value for copper female

    80-155 UG/DL, 13-24 UMOL/L

  • 27

    Normal value for ceruloplasmin

    23-50 MG/DL

  • 28

    2ND most abundant trace element which is cofactor for >300 enzymes

    ZINC

  • 29

    Important in protein and nucleic acid synthesis

    ZINC

  • 30

    Essential for the synthesis and action of insulin

    ZINC

  • 31

    Zinc containing metalloenzyme

    CARBONIC ANHYDRASE, ALKALINE PHOSPHATASE, DNA AND RNA POLYMERASE, CARBOXYPEPTIDASE, ALCOHOL DEHYDROGENASE, SUPEROXIDE DISMUTASE

  • 32

    Zinc is mostly absorbed in the

    DUODENUM

  • 33

    Zinc being transferred into the portal blood

    METALLOTHIONEIN

  • 34

    Zinc in blood is bound to

    ALBUMIN, A-2 MACROGLOBULIN

  • 35

    Contain most of the body's zinc but slowest turnover

    MUSCLE, BONE

  • 36

    Where do metallothionein bound zinc found which can be readily mobilized

    LIVER

  • 37

    Half life of zinc found in muscles and bones

    300 DAY

  • 38

    Half life of metallothionein

    2 WEEK

  • 39

    Zinc deficiency is c'mon in what disorders

    DIABETES MELLITUS, ALCOHOL ABUSE, MALABSORPTION SYNDROME, LIVER AND KIDNEY DISEASE

  • 40

    Rare autosomal recessive disorder with impaired intestinal absorption and transport of zinc

    ACRODERMATITIS ENTEROPATHICA

  • 41

    Factors to consider for zinc laboratory determination

    DIURNAL VARIATION, POSTPRANDIAL VARIATION

  • 42

    Serum value is ___to plasma values

    >10%

  • 43

    RBC zinc is____to plasma zinc

    >10X

  • 44

    Method of choice for zinc in body fluids

    FLAME ATOMIC ABSORPTION SPECTROPHOTOMETRY

  • 45

    Reference testing method for zinc serum or plasma

    INDUCTIVELY COUPLED PLASMA SPECTROPHOTOMETRY

  • 46

    Reference value for zinc plasma

    70-120 UG/DL, 10.7-18.4 UMOL/L

  • 47

    Most abundant trace element

    IRON

  • 48

    Iron load in the human body

    40-50MG/KG BW

  • 49

    Iron containing proteins

    HEMOGLOBIN, COLLAGEN, TYROSINASE, CATECHOLAMINE

  • 50

    Which trace element has effect on cell mediated immunity

    IRON

  • 51

    Stored formed of iron

    FERRITIN, HEMOSIDERIN

  • 52

    What body tissues iron can be found

    MYOGLOBIN, NON HEME ENZYME

  • 53

    Dietary form of iron

    FERROUS

  • 54

    Iron absorption is facilitated by

    ASCORBIC ACID, REDUCING AGENT, ACID PH

  • 55

    How many percent is dietary iron is being absorbed

    5-10%

  • 56

    Glycoprotein that transports iron

    TRANSFERRIN

  • 57

    Transferrin is synthesized in the

    LIVER

  • 58

    Transferrin has high affinity to

    FERRIC ION

  • 59

    Stored form of iron found virtually in all cells which being measured for IDA diagnosis

    FERRITIN

  • 60

    Factors that may increased serum ferritin

    FEVER, ACUTE INFECTION, RHEUMATOID ARTHRITIS, VIRAL HEPATITIS

  • 61

    Quantitative, specific, sensitive involving invasive procedure measurement for iron

    DIRECT

  • 62

    Quantitative measurement for iron includes the following

    QUANTITATIVE PHLEBOTOMY, BONE MARROW BIOPSY, LIVER BIOPSY

  • 63

    Indirect measurement for serum iron

    COLORIMETRIC METHOD, AAS

  • 64

    measurement for serum transferrin

    DIRECT IMMUNOASSAY, TOTAL IRON BINDING CAPACITY

  • 65

    Maximum amount of iron that can bind to serum transferrin

    TOTAL IRON BINDING CAPACITY

  • 66

    Ratio of the plasma iron to TIBC

    TRANSFERRIN RATIO

  • 67

    Serum ferritin is measured via

    IRMA, ELISA, IMMUNOFLUOROMETRIC ASSAY, CHEMILUMINISCENCE ASSAY

  • 68

    Useful marker of body iron stores (pregnancy and neonates) which is sensitive measurement of tissue iron deficiency

    SERUM TRANSFERRIN RECEPTOR

  • 69

    Zinc for iron substition in IDA which substition occurs in the Bone Marrow

    ZINC PROTOPORPHYRIN

  • 70

    Reagent used to extract ZnPP

    ETHYL ACETATE

  • 71

    Method for detecting ZnPP

    HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

  • 72

    Most advanced stage of iron deficiency

    IRON DEFICIENCY ANEMIA

  • 73

    Most c'mon cause of iron overload

    HEREDITARY HEMOCHROMATOSIS

  • 74

    Other disease contributing to iron overload

    SIDEROBLASTIC ANEMIA, CHRONIC HEPATITIS

  • 75

    Normal value for Total Fe

    60-150 UG/DL

  • 76

    Normal value for TIBC

    250-400 UG/DL

  • 77

    Normal value for Iron saturation

    20-55%

  • 78

    Normal value for ferritin male

    15-200 UG/L

  • 79

    Normal value for ferritin Female

    12-200 UG/L

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    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26