Biofilm

Tameyra Stefani Al-Suhairy · 44問 · 1年前

通報

問題一覧

effective in reducing caries in animals and humans

Antibiotics

can demineralize enamel in vitro and produce lesions similar to naturally occurring caries

Oral bacteria

gelatinous mass (soft, translucent and tenaciously adhering) of bacteria adhering to the tooth surface.

Dental plaque

Factors needed for caries initiation 4

Flora, Diet, Susceptible surface, Time

Strep associated with caries Humans 2

Mutans, Sobrinus

Strep associated with caries Rats

rattus

Strep associated with caries hamsters

cricetus

associated with caries primates 2

macacae, downei

collective term for all the serotypes

mutans streptococci or MS

can produce great amounts of acids (acidogenic), are tolerant of acidic environments (aciduric), are vigorously stimulated by sucrose, and appear to be the primary organism associated with caries in man.

MS and Lactobacilli

enamel caries

mutans streptococci or MS

MS and Lactobacilli species

dentin caries

root caries

Actinomycetes species (e.g. Actinomycetes viscosus)

able to produce lactic acid from sucrose

Acidogenic

can live in pH as low as 4.2

Aciduric

adhere to pellicle and contribute to plaque formation. The survival of organisms in the oral environment depends on their ability to adhere to a surface.

s mutans

Able to form large amounts of extracellular, sticky and insoluble glucan plaque matrix

S mutans

total number of bacteria inoculated into the mouth

Threshold space

relatively cell-free layer of precipitated salivary protein material

Pellicle

recognizes plaque as pathogenic only when signs of associated disease are present.

Specific plaque hypothesis

assumes that all plaque is pathogenic

Non specific plaque hypothesis

occur as the process of development of a biological community where with non previously existed

Primary succession

In oral cavity it is the process of normal change in the oral flora occuring over the lifetime of an individual.

Primary succession

process of plaque regrowth after the tooth surface is cleaned

Secondary succession

similar plaque will reform on the teeth after prophylaxis if there is no other change in the oral environmental conditions.

Secondary succession

period of remineralization

Plaque pH above 5.5

period of demineralization

Plaque pH below 5.5

make it easy for acidogenic bacteria to adhere and extracellular matrix facilitates cohesion

Special receptors

favors colonization of acidogenic bacteria and exclusion of non-cariogenic bacteria (e.g., S. sanguis, S. mitis)

high sucrose diet or frequent ingestion of sucrose

Development of bacterial plaque 7

Pellicle (1 µm thick) covers all oral surfaces within 30 minutes to 1 hour after brushing, it becomes colonized by bacteria within 12-24 hours., high sucrose diet or frequent ingestion of sucrose - favors colonization of acidogenic bacteria and exclusion of non-cariogenic bacteria (e.g., S. sanguis, S. mitis), special receptors make it easy for acidogenic bacteria to adhere and extracellular matrix facilitates cohesion, Metabolism of sucrose results in acid production – lactic acid from sucrose., Plaque pH below 5.5 – period of demineralization, Plaque pH above 5.5 – period of remineralization

S. mutans is considered the most cariogenic species of mutans streptococci

True

Actinomyces sp. are microorganisms present in early plaque that can initiate enamel caries formation.

False

Cariogenic bacteria are anaerobic microorganisms that are unable to tolerate acidic environment

False

The extracellular matrix of plaque is a polysaccharide-rich substance mainly composed of glucans.

True

Ecological plaque hypothesis states that any change in the environmental factors will in turn cause change in the balance of oral flora, predisposing a site to the disease.

True

Pellicle is formed by the precipitation of salivary proteins and by the attachment of bacteria

False

Corn-cob colonies of bacteria are early inhabitants of plaque.

False

S. mutans requires high threshold dose in order for them to compete with other oral species.

True

Lactobacillus sp. Initiates dentin caries formation.

True

The early colonizers of plaque are filamentous bacteria.

False

Lactobacillus acidophilus

Actinomyces species

able to produce lactic acid from sucrose

Acidogenic

can live in pH as low as 4.2

Aciduric

S mutans

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