Antibiotic associated pseudomembranous entercolitis fluroquinolones binary toxin

Treatment pseudo membranous entercolitis

Flaccid paralysis

Pulmonary woolsorter's disease Necrotic ulcer with eschar ingestion upper intestinal tract

lysed by botulinum toxin to cause inhibition of the release of acetylcholine

Beta hemolysis

Produce spores Obligate anaerobes Gram (+) cell wall

low virulence Opportunistic pathogen

Mechanism of tetanospasmin

tetanospasmin

c. Botulinum food poisoning is due to

Umbilical stump

Cephalic tetanus

Food poisoning associated with Chinese fried rice cause by

3 aerobic sporeforming

Most common and invasive

TREATMENT Soft tissue infections → Surgical debridement and high dose Penicillin - Hyperbaric oxygen therapy (HBOT)- speed up healing of gas gangrene, carbon monoxide poisoning, infections in which tissues are starved for O2 - For food poisoning → Self-limiting → No need for antibiotics > replace fluids by electrolytes

Metabolic activity of rapidly dividing c. perfringens results to

Anaerobic spore forming 4

b. Anthracis most immunogenic

Wound dibridement Metronidazole passive/active immunization

Passive immunization with human tetanus lg

Persistent back spasm

Active immunization with tetanus toxoid

Woolsorters disease

Food poisoning Eye infection Sepsis