記憶度
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問題一覧
1
Complimentary medicine
2
Botanicals (herbs & plant extracts)
Alternative health care
3
Pharmacokinetics
4
Absorption
5
Absorption
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Absorption
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Distribution
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Distribution
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Metabolism
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Phase l metabolism
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Phase 2 metabolism
12
Kidneys renal disease adjust urine pH to accelerate excretion of the drug
Elimination
13
3 Basic parameters of pharmacokinetics:
Volume of distribution, Clearance, t ½ or drug half-life
14
Bioavailability
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Immediate effects
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Delayed effects
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Cumulative effects
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Loading dose
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Maintenance dose
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Intermittent dose:
21
Pharmacodynamic
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Pharmacodynamics
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Full agonist
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Partial agonist
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Neutral antagonist
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Inverse agonist
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spare receptors
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Full agonist
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Partial agonists
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competitive antagonist
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irreversible
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physiologic
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Tolerance
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Tachyphylaxis
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Pharmaceutical equivalent
36
Therapeutic equivalent
37
Pharmacokinetic
38
Pharmacodynamic
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Displacement
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Interference
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Additive
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Synergism
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Antagonism
44
Pharmacogenomics
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Adverse Drug Reaction
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Adverse Drug Reaction:
47
subject bias
48
Double blind both subject and evaluator
observer bias
49
Case report/case series
50
Cohort
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Case control
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Meta analysis
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Controlled trials (randomized)
54
Graded dose response
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Quantal dose effect response
56
growth hormone erythropoietin interferon
cytokine receptor
57
hypnotic sedative anticonvulsant
Ligand-gated channels
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insulin growth factor
Ligand regulated transmembrane enzymes
59
NO hormones corticosteroids sex hormones vit D thyroid hormone
Intracellular receptors for lipid soluble agents
60
opioid analgesic antibiotics
G-proteins and 2nd messengers
61
dimecaprol heavy metals
chemical
62
Which is NOT a parameter of pharmacodynamics?
clearance
63
This phase of clinical drug evaluation utilizes both healthy subjects as well as those with the disease, in order to determine if the drug works double blind
not sure
64
The branch of pharmacology that studies the use of drugs in the diagnosis, treatment and prevention of diseases
Pharmacotherapeutics
65
Which is a factor that can affect drug absorption
drug solubility
66
If a drug has a long half-life, it means
The drug is eliminated slower from the body.
67
An INCORRECT statement about the oral route of drug administration:
It avoids 1st pass metabolism.
68
This process of pharmacokinetics refers to making a drug more polar thru biotransformation in order for the drug to be eventually eliminated in the kidneys
metabolism
69
drug INDUCER means that a drug
When combined with another may decrease its' bioavailability
70
The apparent space in the body that is able to contain a drug refers to a drug's
Volume of distribution
71
A drug AGONIST is described as:
A drug that binds with a receptor to produce an effect
72
This refers to the margin of safety of a drug, and is measured by a drugs' toxic dose over a drugs' effective dose:
Therapeutic index