記憶度
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1
term applied to the accumulated excretory and secretory products which is a viscous fluid discharged by the salivary glands into the oral and vestibular cavities, by the major and minor ducts.
SALIVA
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Hypotonic fluid relative to plasma
SALIVA
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Average slightly acid
6.8
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quantity of saliva that secreted per day.
750 ml
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produced saliva by submandibular glands
60% to 70%
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produced saliva by parotid
25% to 35%
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produced saliva by sublingual glands
5% or less
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5 inorganic Constituents
Sodium (Na+), Chloride (Cl-), Bicarbonate (HCO3-), Potassium (K+), Phosphate
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5 Nitrogenous Compound
Amino acids, Peptides, Creatinine, Uric Acid, Urea
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5 proteins
amylase or ptyalin, lysozymes, Glycoproteins, IgA, Blood protein traces
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obtained directly from the gland. clear, colorless fluid.
pure saliva
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frothy and opalescent fluid containing water, protein, mineral salts, ptyalin, mucin, food particles, desquamated epithelial cells, and salivary corpuscles.
mixed saliva
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Results from sight or smell of food or from stimulating material of the oral cavity.
active saliva
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occurs in absence of excitation.
Resting Saliva
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Ability to be drawn out into long elastic threads.
Spinnbarkeit
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sticky
Viscosity
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power to resist change in the pH when acid or alkali are added to a solution.
Buffering power
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bicarbonate, phosphate and protein
Buffering power
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Chemical reaction in w/c compounds with a high molecular weight are reduce to a compound of lower molecular weight.
Reducing power
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4 properties of saliva
Spinnbarkeit, Viscosity, Buffering power, Reducing power
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no change in cytoplasm of the gland.
merocrine
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secretion passes the duct
exocrine
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important for metabolism because they play an important part in modification, absorption, utilization and excretion of food substances.
salivary glands
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transform and secrete materials coming from the circulatory fluid of the body
Primary function
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to excrete certain substances.
Secondary function
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3 major glands (extrinsic glands)
Parotid, Submandibular (submaxillary), Sublingual
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2 Minor Glands (intrinsic glands)
Labial, Buccal
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Parotid
Stensen’s;Serous
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Submandibular
Wharton’s; mainly Serous
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Sublingual; mixed (mainly mucous)
Bartholin’s (major)/ Ravinian (minor)
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Labial
Mixed (mainly mucous)
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anterior lingual
Mixed (mainly mucous)
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posterior lingual
Mucous
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buccal
Mixed (predominantly mucous)
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Von Ebner ‘s gland
Serous
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Palatine
Mucous
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Glossopalatine
Mucous
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5 DUCT SYSTEM OF THE SALIVARY GLAND
Terminal secretory end pieces – acinar cells, Intercalated ducts, Striated cells, Main excretory duct, Oral cavity
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3 FACTORS AFFECTING FLOW RATE
Type of salivary gland, Nature of the stimulation, Duration of the stimulation
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the removal of food that enters the mouth
oral clearance
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is the time taken either to clear the substances from the mouth or to reduce to a very low concentration
Oral Clearance Rate
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ability of the saliva to maintain the pH when exposed to acid
SALIVA BUFFER CAPACITY
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3 important buffer system in human being
Bicarbonate, phosphate, protein
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Main buffer system in human saliva •Most effective as a buffer at pH 6 •Contribution to the overall buffer capacity
BICARBONATE BUFFER SYSTEM
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percentage of unstimulated saliva BICARBONATE BUFFER SYSTEM
50
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percentage of stimulated saliva BICARBONATE BUFFER SYSTEM
90%
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Most effective as buffer at pH 6.8
PHOSPHATE BUFFER SYSTEM
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-50% in unstimulated saliva -minor contribution for the stimulated saliva
PHOSPHATE BUFFER SYSTEM
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Most effective as a buffer at pH value of less than 5
PROTEIN BUFFER SYSTEM
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Some salivary pH increase the viscosity of the saliva when the pH becomes acidic to cover and physically protect the teeth against acid load
PROTEIN BUFFER SYSTEM
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decrease in salivary function
Hypofunction
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increase in salivary function
Hyperfunction
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Any change in the quantitative and/or qualitative change in output of SALIVA
SALIVARY GLAND DYSFUNCTION
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Genuine salivary hyperfunction
Sialorrhoea
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Cerebral palsy Parkinson’s disease Mentally handicapped patient Neuroleptic medications in adults
Drooling
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common condition in people with underlying disease or those who take certain medication
SALIVARY GLAND HYPOFUNCTION
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term based on objective measures of the saliva production
Hyposalivation
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decrease salivary flow rate change in composition
xerostomia
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Calcified masses within the salivary duct (saliva stones ) •Asymptomatic and unilateral
SIALOLITHS
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Bacterial sialadenitis relatively rare condition usually in elderly who have reduced salivary flow due to systemic disease
SIALADENITIS
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Characterized by acute tender swelling of the salivary gland Mumps is the most common form
SIALADENITIS
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HIV / AIDS, epidemic parotitis
infections
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Diabetes mellitus, hyper/hypothryoidism
Hormonal disorders
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Rheumatoid arthritis, Sjogren’s Syndrome, sarcoidosis
Autoimmune disease
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Cystic fibrosis, ectodermal dysplasia
Hereditary disorders
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Malnutrition, eating disturbance, bulimia, anorexia nervosa, dehydration
Metabolic disturbances
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4 SALIVARY GLAND TUMOR
parotid, submandibular, sublingual, minor
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lead cadmium copper
pollutants
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Caused by mucosal irritation or Idiopathic
Sialorrhoea
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Salivary glands of man are classified according to the nature of secretion
Exocrine
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Salivary glands of man are classified according to the behavior of glands
Merocrine
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the composition of saliva depends strongly on the flow rate
true
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Normal daily production of saliva
0.5 to 1.5 liters
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Ph of saliva acidity
5.6
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ph of saliva alkalinity
7.6
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ph of saliva average slightly acid /neutral
6.8