Flukes Possess primitive digestive tract

Tissue dwelling flukes 4

2 intermediate host First: nail 2nd: freshwater fish, crabs or crayfish and aquatic plants

Transmitted by: Ingestion of raw or inadequately cook 2nd intermediate host

Infective stage (tissue dwelling)

Schistosomes which are composed of: s. Japonicum s. Mansoni S.haematobium

Intermediate host: freshwater snail

Major mode of transmission of Blood dwelling flukes

Blood dwelling flukes pathogenic stage is adult worm EXCEPT

Adult worms localized to inferior mesenteric veins

Worms localized to the veins around urinary bladder

Adult female migrates to the portal vein where egg laying may occurs

Higher risk for development of liver cancer

Cancer of urinary bladder

Obstructive jaundice (2)

Duodenal ulcer

Mimic pulmonary tuberculosis

Cholanglocarcinoma

lid like structure seen on eggs of f. buski and f. hepatica

Sputum

Katayama fever

S-japonicum associated with

Drug choice for most trematode