Elderly and immunocompromised Erosion - bronchi and vessels Spread- airways, lymphatic channels or vascular system

Chronic granuloma

Lack sensation Hyperpigmentation spots

Not transmitted by man-man MAC group 3- non photochromogen

Acute inflammatory reaction

Active cell medicated immunity Borderline tuberculoid

Lung disease

Tuberculoid

AIDS patients Causes lung disease

hansens bacilli

Skin infection and swimming pool granuloma

High lipid content (mycolic a) → hydrophobic, resistant to disinfectant Survive outside human body

Acid fast rod Foam cells Affects skin and peripheral nerves Chronic disease: disfigurement

Lack of sensation Hyperpigmentation spots

Ziehl neelsen Kinyon fluorochrome stain

Mot: inhalation of infectious droplets Direct contact

'

Coalescent tubercles with central caseation Heal with fibrosis or progress

Common in soil water, dust, domestic animals

Less virulent than m. Tuberculosis Infects aids patients

Tuberculoid Borderline tuberculoid lepromatous

anergic leprosy

Mot: inhalation of infectious droplets Direct contact

Hematogenous spread of millet seed

Source of energy for organism to survive in the environment

Infects healthy people

Skin infections

lepromatous