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問題一覧
1
Key Procoagulant Cofactors:
Tissue Factor (TF), Factor V, Factor VIII, High-Molecular-Weight Kininogen (HMWK)
2
Transmembrane receptor for factor VIIa which initiates coagulation.
Tissue Factor
3
Location: Extravascular cells (e.g., fibroblasts, smooth muscle cells).
Tissue Factor
4
The activation of the tissue factor leads to coagulation via factor?
VIIa
5
The expression of the tissue factor increases in leukocytes with?
Inflammation and Sepsis
6
Cofactor to factor Xa in the prothrombinase complex.
Factor V
7
Location: Plasma and platelet α-granules
Factor V
8
Activation: Released during platelet activation
Factor V
9
Inactivation: By protein C to Vi.
Factor V
10
Inactivation of Factor V by?
Protein C to Vi
11
Cofactor to factor IX in the intrinsic tenase complex.
Factor VIII
12
The regulation is activated and inactivated by thrombin.
Factor VIII
13
Factor VIII regulation is activated and inactivated by?
Thrombin
14
Cofactor to factor XIIa and prekallikrein.
High-Molecular-Weight Kininogen (HMWK)
15
The role is to be part of the intrinsic contact factor complex.
High-Molecular-Weight Kininogen (HMWK)
16
Conditions: Activated in presence of foreign objects or inflammation.
High-Molecular-Weight Kininogen (HMWK)
17
It is a thrombin cofactor, which regulates coagulation and fibrinolysis.
Thrombomodulin
18
Activates protein C and TAFI, suppresses factors V and VIII.
Thrombomodulin
19
Cofactor to protein C and TFPI.
Protein S
20
The main role is to regulate coagulation
Protein S
21
A cofactor to Z-dependent protease inhibitor (ZPI).
Protein Z
22
It's main role is to assists in coagulation control.
Protein Z
23
Procoagulant
Tissue Factor , V, VIII, High-Molecular-Weight Kininogen
24
Control (Protein C) Antifribrinolytic (TAFI)
Thrombodulin
25
Control
Thrombodulin , Protein S, Protein Z
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The tissue factor binds to?
VIIa
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The Cofactor V binds to?
Xa
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The Cofactor VIII binds to?
IXa
29
The Cofactor HMWK binds to?
XIIa, pre-kallikrein
30
The cofactor of thrombodulin binds to?
Thrombin
31
The cofactor protein S binds to?
Protein C, TFPI
32
The cofactor Protein Z binds to?
ZPI