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Cofactors in Hemostasis
  • Almira Coleen

  • 問題数 32 • 1/30/2025

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    問題一覧

  • 1

    The main role is to regulate coagulation

    Protein S

  • 2

    The Cofactor HMWK binds to?

    XIIa, pre-kallikrein

  • 3

    Conditions: Activated in presence of foreign objects or inflammation.

    High-Molecular-Weight Kininogen (HMWK)

  • 4

    Cofactor to protein C and TFPI.

    Protein S

  • 5

    Transmembrane receptor for factor VIIa which initiates coagulation.

    Tissue Factor

  • 6

    Factor VIII regulation is activated and inactivated by?

    Thrombin

  • 7

    Inactivation: By protein C to Vi.

    Factor V

  • 8

    It is a thrombin cofactor, which regulates coagulation and fibrinolysis.

    Thrombomodulin

  • 9

    Activation: Released during platelet activation

    Factor V

  • 10

    Location: Plasma and platelet α-granules

    Factor V

  • 11

    The tissue factor binds to?

    VIIa

  • 12

    The regulation is activated and inactivated by thrombin.

    Factor VIII

  • 13

    Control

    Thrombodulin , Protein S, Protein Z

  • 14

    Control (Protein C) Antifribrinolytic (TAFI)

    Thrombodulin

  • 15

    Cofactor to factor IX in the intrinsic tenase complex.

    Factor VIII

  • 16

    Key Procoagulant Cofactors:

    Tissue Factor (TF), Factor V, Factor VIII, High-Molecular-Weight Kininogen (HMWK)

  • 17

    The cofactor of thrombodulin binds to?

    Thrombin

  • 18

    The activation of the tissue factor leads to coagulation via factor?

    VIIa

  • 19

    Procoagulant

    Tissue Factor , V, VIII, High-Molecular-Weight Kininogen

  • 20

    The Cofactor VIII binds to?

    IXa

  • 21

    The expression of the tissue factor increases in leukocytes with?

    Inflammation and Sepsis

  • 22

    Location: Extravascular cells (e.g., fibroblasts, smooth muscle cells).

    Tissue Factor

  • 23

    The Cofactor V binds to?

    Xa

  • 24

    Inactivation of Factor V by?

    Protein C to Vi

  • 25

    Cofactor to factor XIIa and prekallikrein.

    High-Molecular-Weight Kininogen (HMWK)

  • 26

    The role is to be part of the intrinsic contact factor complex.

    High-Molecular-Weight Kininogen (HMWK)

  • 27

    Cofactor to factor Xa in the prothrombinase complex.

    Factor V

  • 28

    Activates protein C and TAFI, suppresses factors V and VIII.

    Thrombomodulin

  • 29

    The cofactor Protein Z binds to?

    ZPI

  • 30

    A cofactor to Z-dependent protease inhibitor (ZPI).

    Protein Z

  • 31

    It's main role is to assists in coagulation control.

    Protein Z

  • 32

    The cofactor protein S binds to?

    Protein C, TFPI