問題一覧
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Are cosmetic fungal infections of the skin or shaft
Superficial mycoses
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- No living tissue invaded - No cellular response from the host - No pathological changes elicited
Superficial Mycoses
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Causative agent: Malassezia furfur
Tinea Versicolor
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Characterized by scaly patches of hypo to hyper pigmentation of skin of moist humid areas
Tinea Versicolor
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Tinea Versicolor other term?
Pityriasis Versicolor
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Noninflammatory and Nonpruritic (rarely pruritic) Lesions
Tinea Versicolor
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Areas rich in sebaceous glands are commonly involved
Tinea Versicolor
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Seborrheic dermatitis Atopic dermatitis Folliculitis Disseminated infection
Tinea Versicolor
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Dandruff in adults; Cradle cup in babies
Seborrheic dermatitis
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Laboratory Diagnosis: Specimen used for Tinea Versicolor?
Skin scrappings
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Laboratory Diagnosis Microscopic examination uses for Tinea Versicolor?
10% KOH preparation
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Microscopic Examination: - Cluster Budding yeast - Spaghetti and meatballs appearance
Tinea Versicolor
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Culture · No growth in routine fungal culture medium ·Yeast like colonies may observed only after the culture medium is overlaid with olive oil
Tinea Versicolor
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- Cream-colored, moist, and smooth - SDA culture with olive oil overlay: Fried egg colonies appear
Tinea Versicolor
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Tinea Versicolor urease?
Positive
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Wood's lamp - golden yellow fluorescence
Tinea Versicolor
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Wood's lamp - golden yellow fluorescence
Tinea Versicolor
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golden yellow fluorescence
Wood's lamp
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M. Furfur stained with Lactophenol Cotton blue
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Malassezia furfur growing on a SDA with olive oil
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Wood's lamp
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Causative agents: Hortaea werneckii Exophiala werneckii Phaeoannellomyces werneckii
Tinea Nigra
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Characterized by painless, black, non-scaly patches present on the palm and sole; more commonly in females.
Tinea Nigra
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Caused by a black colored yeast-like fungus - Hortaea wernecki
Tinea Nigra
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Caused by a black colored yeast-like fungus
Hortaea wernecki
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Treatment: Topical ketoconazole cream
Tinea Nigra
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Tinea Nigra uses what type of specimen for laboratory diagnosis:
Skin scrapings from the periphery of the lesion
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Microscopic examination ·Branched, septate hyphae ·2 celled oval yeast cells with melanized cell walls
Tinea Nigra
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Culture ·Black, yeasty colonies · Develop short olive gray mycelia with age
Tinea Nigra
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- Infection of the hair shaft that produces hair breakage - Due to poor personal hygiene - May disseminate in immunocompromised individuals
Piedra
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Fungal infection of facial, axillary, or genital hairs
White Piedra
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·Less commonly the scalp
White Piedra
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Causative agent: Trichosporon spp.
White Piedra
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Soft, white, yellowish, beige, or greenish nodules on the hair shaft
White Piedra
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Less firmly attached
White Piedra
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White Piedra uses what type of microscopic examination?
10% KOH or 25% & NaOH w/ glycerol
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- Intertwined hyaline septate hyphae - Breaking up into oval or rectangular arthroconidia
White Piedra
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Culture: SDA or PDA
White Piedra
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- Raised, waxy appearance colonies - Radial furrow and irregular folds
White Piedra
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White Piedra is a urease?
Positive
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The white Piedra also mounts?
Lactophenol Cotton Blue (LPCB)
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- Showed septate hyphae, arthroconidia and budding blastoconidia
White Piedra
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- Fungal infection of the hair scalps
Black Piedra
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Less commonly in beard and pubic areas
Black Piedra
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Causative agent: Piedraia hortae
Black Piedra
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Black Piedra, Causative agent:
Piedraia hortae
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Hard, dark brown to black gritty nodules on hair shaft
Black Piedra
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carbonaceous; can house an asci
Black Piedra
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Firmly attached to the hair shaft
Black Piedra
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Black Piedra uses what type of specimen?
Infected hair
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Black Piedra uses what type of microscopic examination?
10% KOH
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- Compact masses of dark, septate hyphae - Round to oval asci containing 2-8
Black Piedra
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Culture: SDA
Black Piedra
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Black Piedra Culture:
SDA
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Nodules: Over and around the hair shaft, hard, difficult to detach from the hair
Piedraia hortae
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Nodules: On the surface of the hair shaft, softer, easy to separate from hair
Trichosporon spp
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Piedraia hortae
Black Piedra
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Trichosporon spp.
White Piedra
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Direct Examination: Arthrospores and blastospore can be seen
Trichosporon spp.
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Direct Examination: Tightly packed dichotomous branched hyphae
Piedraia hortae
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Presence of asci: Negative
Trichosporon spp.
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Presence of asci: Positive
Piedraia hortae
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A lipophilic fungus
Malassezia furfur