問題一覧
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Utilizes the specialty of chemistry to study human beings. -An applied science when analysis are performed on body fluids or tissues for diagnosis or treatment of disease.
Clinical Chemistry
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Role of Clinical Chemistry
Measure the chemical changes in the body for diagnosis, therapy, and prognosis of disease., Measure the concentration of a particular constituent (the analyte) in body fluids.
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Role of Medical Technologist (Must understand the tools)
Equipments , Reagents, Principle of the testing methods , Knowledge of the medical uses of the determinations
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Biological substance that poses a threat to the health of living organism, primarily humans. Chain of infection. (Transmission)
Biologic Hazard
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Biologic Hazard/Pathogenic Microorganisms
Bacteria , Viruses , Fungi , Prions , Toxins
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Necessary to prevent infection
Chain of Infection
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Requires continuous link between three elements
Source, Mode of Transmission , Suspectible Host
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Refers to the location of potentially harmful microorganisms
Source
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Direct contact, Inhalation, Ingestion
Mode of Transmission
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Individual who is at risk of infection
Host
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Types of Biologic Hazards
Pathogenic Microorganisms , Bioactive Substances , Allergic Agents
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Toxins produced by microorganisms, plants, and animals
Bioactive Substances
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Substances that can cause allergic reactions
Allergic Agents
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Hospitals, laboratories, and clinics where infectious agents are handled
Medical and Clinical Settings
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Soil, water and air that may contain pathogenic organisms
Natural Environment
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Facilities involved in genetic engineering, pharmaceutical development, and biological research
Biotechnology and Research
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Physical contact with an infected person or contaminated surface
Direct Contact
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Inhalation of airborne pathogens (droplets)
Airborne Transmission
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Spread through vectors (mosquitoes, ticks, fleas)
Vector-Borne Transmission
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Ingestion of contaminated food or water
Food and Water
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Non-infectious dry biological waste disposal
Black
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Non-infectious wet biological waste disposal
Green
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Infectious pathologic biological waste disposal
Yellow
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Biological Waste Disposal: Chemical Waste and Heavy Metals
Yellow with Black Band
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Biological Waste Disposal: Radioactive Waste
Orange
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Biological Waste Disposal: Sharps
Red
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Biological Waste Disposal: Soiled Linens
White or Clear Plastics
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Biological Waste Disposal: Autoclaving
Light Blue or Transparent w/ Blue Inscription
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The most common disinfectant is 1:10 solution of ___________ (household bleach) prepared weekly and stored in a plastic (not a glass)
Sodium Hypochlorite
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(sterilization) uses high pressure steam to realize waste, killing all pathogens (commonly used for laboratory waste)
Autoclaving
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(Burning Waste) involves burning biological waste at high temperature, reducing it to ash
Incineration
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Often used for liquid waste
Chemical Disinfection
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(Burial) requires careful regulation to avoid contamination
Landfill Disposal
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(Composting) microorganisms break down the waste into harmless by products; more applicable to agriculture and food industry waste
Biological Treatment
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Are a specific category of medical and laboratory waste that includes an items that can puncture or cut the skin. Causing injuries and transmitting infections
Sharps
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Can cause puncture or wounds (Bloodborne Pathogens)
Needlestick Injuries
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Can lead to exposure to infectious materials and increase the risk of infection
Cuts and Laceration
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Refers to the risk posed by chemicals that can cause harm to human health or the environment
Chemical Hazards
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Immediate harm upon exposure
Acute
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Long-term health effects
Chronic
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Cyanide, Carbon Monoxide
Acute
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Asbestos, Benzene
Chronic
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Easily ignite and cause fires
Flammable Chemicals
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Can cause severe damage to tissues and materials
Corrosive Chemicals
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Can undergo violent reactions under certain conditions
Reactive Chemicals
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Known to cause cancer
Carcinogens
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Cause genetics mutations
Mutagens
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Cause developmental abnormalities
Teratogens
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Refers to dangerous conditions where a person can encounter energized equipment or conductors
Electrical Hazard
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RACE
Fire/Explosive Hazards
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NFPA
National Fire Protection Association
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Environmental factors that can cause harm to human body without necessarily touching it Injuries, health issues, accidents
Physical Hazards
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Most frequently used reagent in the laboratory
Water
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Purified by distillation
Distilled Water
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Purified by ion exchange
Deionized Water
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Reverse osmosis; pumps water across semipermeable membrane
RO Water
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Reagent Grade Water: (Ultrapure) Requiring minimum interference; for preparation of standard solutions, buffer and in analytical techniques
Type I
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Reagent Grade Water: Preparation of reagents and solutions, general laboratory procedures
Type II
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Reagent Grade Water: Glassware Washing
Type III
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Dissolved in liquid
Solute
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Biologic Solutes
Analytes
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Liquid in which solute is dissolved
Solvent
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The pressure required to stop the flow of solvent into the solution through a semipermeable membrane
Osmotic Pressure
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Liquid solvent is in equilibrium with the water vapor
Vapor Pressure
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Temperature at which a vapor pressures of a solid and liquid phases are the same
Freezing Point
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Temperature are which the vapor pressure of the solvent reaches one atmosphere
Boiling Point
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Redox/Reduction Potential: measure of the ability of a solution to accept or donate electrons
Oxidation
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Donate electrons
Reducing Agents
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Accept Electrons
Oxidizing Agents
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How electricity passes through a solution
Conductivity
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Resistance to the passage of electrical current
Resistivity
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Used a colored liquid (red or other colored material) Encased in Plastic or Glass 20°C - 40°C Continuous line of liquid Free from separation or bubbles NIST
Liquid-in-glass Thermometer
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Temperature-sensitive resistors SRM, NIST Fast reading and accurate Ideal for applications requiring immediate temperature adjustment
Electronic Thermometer or Thermistor
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Direct contact, Inhalation, Ingestion
Mode of Transmission
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Direct contact, Inhalation, Ingestion
Mode of Transmission