Mod 1-7

Mod 1-7
95問 • 1年前
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    問題一覧

  • 1

    Which of the following statements supports the axiom, “All living organisms have a common ancestor?”

    Building blocks of cells in the body are identical in all species.

  • 2

    The following are characteristics of a living organism.

    Both A and B

  • 3

    He introduced the word biochemistry.

    Neuberg

  • 4

    Which statement best describe the axiom, “Living cells function as isothermal chemical changes?”

    The formation of ATP from ADP and vice versa.

  • 5

    The following can describe the axiom “Cells are capable of regulating their metabolic reactions and the biosynthesis of their enzymes to achieve maximum efficiency and economy,” except

    Each organism has their own sets of nucleic acids and proteins.

  • 6

    Why biochemistry is important in medical laboratory science?

    All of these.

  • 7

    An organic compound is one that:

    Contains carbon

  • 8

    Polysaccharides are

    Large molecules made of many smaller simple sugars

  • 9

    Polysaccharides are carbohydrates, which give large number of monosaccharides on hydrolysis.

    Carbohydrates

  • 10

    What type of macromolecules are dominantly seen in cell walls?

    Carbohydrates

  • 11

    Movement of water from an area of higher to an area of lower water concentration through selectively permeable membrane.

    Osmosis

  • 12

    Vesicular transport is the

    Both a and b

  • 13

    Type of endocytosis that involves the nonselective uptake of tiny droplets of extracellular fluid

    Pinocytosis

  • 14

    The basic structural unit of the plasma membrane is the

    Lipid bilayer

  • 15

    Integral proteins can function in the cell membrane in all the following ways except:

    As an exocytosis vesicle

  • 16

    Part of the cell that is described to be networks of protein filaments that extend throughout the cytoplasm, providing cellular shape and organizations.

    Cytoskeleton

  • 17

    Functions for ATP production

    Mitochondria

  • 18

    The following factors influence the diffusion rate of substances through a plasma membrane except?

    All of the above

  • 19

    Which of the following statements regarding the nucleus are true? 1. Nucleoli within the nucleus are the sites of ribosome synthesis. 2. Most of the cell’s hereditary units, called genes, are located within the nucleus. 3. Proteins synthesis occurs within the nucleus. 4. In non-dividing cells, DNA is found in the nucleus in the form of chromatin.

    1, 2, 4

  • 20

    Stage when chromatin fibers condense and shorten to form chromosomes

    Prophase

  • 21

    Which one of the following types of bonds is covalent?

    Disulfide

  • 22

    What is the pH of a solution containing 0.2 M acetic acid (pKa=4.7) and 0.1 M sodium acetate?

    5.4

  • 23

    A weak acid HA, has a pKa of 5.0. If 1.0 mol of this acid and 0.1 mol of NaOH were dissolved in one liter of water, what would the final pH be?

    4.05

  • 24

    All of the following are true regarding vital force theory except:

    Urea can be synthesized from simple inorganic compounds.

  • 25

    15. A patient seen in the ER has ingested antifreeze in a suicide attempt. Other than bicarbonate, which one of the following is the major buffer of acids to help maintain the pH in the blood within the range compatible with life?

    Hemoglobin

  • 26

    The functional group that help stabilize the shape of proteins.

    –SH

  • 27

    Organic compounds that function primarily to provide a readily available source of chemical energy to generate the ATP that drives metabolic reactions are:

    Carbohydrates

  • 28

    The body’s most highly concentrated form of chemical energy is

    Triglyceride

  • 29

    The disaccharide maltose is formed by combining what monosaccharides?

    Glucose + glucose

  • 30

    The disaccharide sucrose is formed by combining what monosaccharides?

    Glucose + fructose

  • 31

    When proteins are heated or pH is changed, their tertiary structure is ruptured and it loses biological activity. This process is called _________________.

    Denaturation

  • 32

    Lipid and protein particles that are bonded together to make lipid more water soluble is termed as _______________.

    Lipoproteins

  • 33

    Type of protein structure, which have the unique sequence of amino acids that are linked by covalent peptide bonds.

    Primary structure

  • 34

    Which of the following structures is a 20:2 (Δ4,9) fatty acid?

    CH3(CH2)2CH=CH(CH2)3CH=CH(CH2)9COOH

  • 35

    Which of the following statements is not true concerning DNA?

    It is composed of a single strand of nucleotides.

  • 36

    All of the following are Nonpolar, aliphatic amino acids except

    Serine

  • 37

    Which of the following is not an essential amino acid?

    Proline

  • 38

    Of the 20 standard amino acids, only ______________ is not optically active. The reason is that its side chain is ____________.

    Glycine: is a hydrogen atom

  • 39

    Which among the following is a non-essential amino acid?

    Serine

  • 40

    Peptide bond is a _________.

    Covalent bond

  • 41

    Which of the following statements is false?

    Secondary structure of a protein determines how it folds up into a unique three-dimensional structure.

  • 42

    Tertiary conformation of proteins is maintained by 3 types of bonds namely ionic, hydrogen and __________.

    Disulfide

  • 43

    Which of the following is true?

    The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine stabilizes protein tertiary structure.

  • 44

    In 3° structure of proteins, folding and shaping is done by __________.

    Hydrophobic interaction

  • 45

    β-pleated sheets are the examples of _________.

    Secondary structure

  • 46

    Which of the following are known as helix breakers?

    Proline and glycine

  • 47

    A process by which a protein structure assumes its functional shape or conformation is?

    Folding

  • 48

    Which of the following is true about Michaelis-Menten kinetics?

    It describes single substrate enzymes.

  • 49

    When the velocity of enzyme activity is plotted against substrate concentration, which of the following is obtained?

    Hyperbolic curve

  • 50

    The rate-determining step of Michaelis-Menten kinetics is __________.

    The complex dissociation step to produce products.

  • 51

    What is the general mechanism of an enzyme?

    It acts by reducing the activation energy.

  • 52

    The allosteric inhibitor of an enzyme ___________.

    Participates in feedback regulation.

  • 53

    In the case of allosteric enzymes what is the graphical representation when initial velocity is plotted against substrate concentration?

    Sigmoid curve

  • 54

    Which is the enzyme that acts as a regulatory enzyme in a four-step metabolic pathway?

    First enzyme

  • 55

    A certain enzyme will hydrolyze egg white but not starch. Which statement best explains this observation?

    Enzyme molecules are specific in their actions.

  • 56

    The red precipitate formed when glucose is heated with “Benedict’s reagent” is

    Cuprous oxide

  • 57

    Fructose and Glucose can be distinguished by ___________

    Seliwanoff’s test

  • 58

    Which of the following is an example of monosaccharide?

    Galactose

  • 59

    In which of the following forms, glucose is stored in plants?

    Starch

  • 60

    In maltose, between which of the following carbons there is a linkage?

    C1, C4

  • 61

    The following structure is what carbohydrate?[object Object]

    β-D-glucose

  • 62

    Breakdown of glycogen to glucose in an example of

    Catabolism

  • 63

    Which of the following carbohydrates is a triose?

    Glyceraldehyde

  • 64

    Which of the following are found in connective tissues?

    Glycosaminoglycan

  • 65

    Which of the following enzyme catalyzes the first step of glycolysis?

    Hexokinase

  • 66

    What is the general term used for the anaerobic degradation of glucose to obtain energy?

    Fermentation

  • 67

    Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?

    Phosphofructokinase-1

  • 68

    Which one of the following metabolites is used by all cells for glycolysis, glycogen synthesis, and the hexose monophosphate shunt pathway?

    Glucose-6-phosphate

  • 69

    After digestion of a piece of cake that contains flour, milk, and sucrose as its primary ingredients, the major carbohydrate products entering the blood are which one of the following? Choose the one best answer.

    Glucose, fructose, and galactose

  • 70

    Glycolysis converts ___________

    Glucose into pyruvate

  • 71

    In the pentose phosphate pathway, the major products are ____________.

    Ribulose and NADPH

  • 72

    What is the first reaction of the pentose phosphate pathway?

    Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone.

  • 73

    The pentose-phosphate pathway generates which one of the following?

    Xylulose-5-phosphate by one of the oxidative reactions.

  • 74

    Which one out of the following enzymes acts in the pentose phosphate pathway?

    6-phosphogluconate dehydrogenase

  • 75

    Oxidation of 3 molecules of glucose by pentose phosphate pathway results in the production of ____________.

    3 molecules of pentose, 6 molecules of NADPH and 3 molecules of CO2

  • 76

    Which one of the following statements is correct about the pentose phosphate pathway?

    It generates 6 moles of CO2 for each mole of glucose consumed.

  • 77

    Thiamine pyrophosphate is a coenzyme of what enzyme?

    Transketolase

  • 78

    Conversion of xylulose 5-phosphate to ribulose 5-phosphate is catalyzed by ___________.

    Phosphopentose epimerase

  • 79

    Which of the following statements is correct about the reductive pentose phosphate pathway?

    Transaldolase transfers 2 carbon units.

  • 80

    The use of NADPH generated from pentose phosphate pathway cannot be ____________.

    Oxidized in the electron transport chain to provide 38 ATPs.

  • 81

    The deficiency of which of the following enzyme leads to galactosemia?

    Galactokinase

  • 82

    The conversion of which of the following involves two nucleotide derivatives?

    Galactose 1-phosphate to glucose 1-phosphate

  • 83

    A 4-week-old baby is being seen by the pediatrician because of frequent vomiting after meals and tenderness in the abdomen. Upon examination, the physician noted an enlarged liver and a hint of cataract formation in both of the child’s eyes. A urine dipstick test for a reducing sugar gave a positive result. Blood glucose levels were slightly below normal. The compound that reacted with the urine dipstick test was most likely which one of the following?

    Galactose

  • 84

    Which of the following enzyme is responsible for the conversion of glucose 1-phosphate to glucose 6- phosphate?

    Phosphoglucomutase

  • 85

    The enzyme responsible for the conversion of galactose to galactitol.

    Aldose reductase

  • 86

    Glucagon and epinephrine stimulate glycogen breakdown to glucose 6-phosphate ________.

    Indirectly by first stimulating adenylate cyclase to make cAMP.

  • 87

    Glucagon is released from ___________.

    Pancreas

  • 88

    Glucose 6-phosphatase is present only in ___________.

    Liver

  • 89

    In glycogen degradation, the enzyme responsible to convert glycogen to glucose 1-phosphate is

    Glycogen phosphorylase

  • 90

    During meal (therefore, in a non-fasting state), blood glucagon is ________, while blood insulin is ____________.

    Decreased; increased

  • 91

    In relation to question number 5, in a non-fasting state, glycogen degradation is __________ while glycogen synthesis is ______________.

    Decreased; increased

  • 92

    This is the glycogen storage disease wherein there is deficiency of the glycogen branching enzyme, transglucosidase.

    Type IV

  • 93

    The Andersen disease, which is an example of GSD, is caused by the deficiency of what enzyme? Glucosyl 4:6 transferase

    Glucosyl 4:6 transferase

  • 94

    In the liver, during glycogen degradation, the enzyme phosphoglucomutase converts ______________.

    Glucose 1-phosphate to glucose 6-phosphate

  • 95

    Which of the following is INCORRECTLY matched?

    Type VI: McArdle

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    sjc L3&L4

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    HIS L3

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    P2

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    CPH P2

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    CPH P2

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    P2

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    P2

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    Reviewer · 100問 · 1年前

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    CFU CPH 17-23

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    CFU HIS P1

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    60問 • 1年前
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    Reviewer · 47問 · 1年前

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    問題一覧

  • 1

    Which of the following statements supports the axiom, “All living organisms have a common ancestor?”

    Building blocks of cells in the body are identical in all species.

  • 2

    The following are characteristics of a living organism.

    Both A and B

  • 3

    He introduced the word biochemistry.

    Neuberg

  • 4

    Which statement best describe the axiom, “Living cells function as isothermal chemical changes?”

    The formation of ATP from ADP and vice versa.

  • 5

    The following can describe the axiom “Cells are capable of regulating their metabolic reactions and the biosynthesis of their enzymes to achieve maximum efficiency and economy,” except

    Each organism has their own sets of nucleic acids and proteins.

  • 6

    Why biochemistry is important in medical laboratory science?

    All of these.

  • 7

    An organic compound is one that:

    Contains carbon

  • 8

    Polysaccharides are

    Large molecules made of many smaller simple sugars

  • 9

    Polysaccharides are carbohydrates, which give large number of monosaccharides on hydrolysis.

    Carbohydrates

  • 10

    What type of macromolecules are dominantly seen in cell walls?

    Carbohydrates

  • 11

    Movement of water from an area of higher to an area of lower water concentration through selectively permeable membrane.

    Osmosis

  • 12

    Vesicular transport is the

    Both a and b

  • 13

    Type of endocytosis that involves the nonselective uptake of tiny droplets of extracellular fluid

    Pinocytosis

  • 14

    The basic structural unit of the plasma membrane is the

    Lipid bilayer

  • 15

    Integral proteins can function in the cell membrane in all the following ways except:

    As an exocytosis vesicle

  • 16

    Part of the cell that is described to be networks of protein filaments that extend throughout the cytoplasm, providing cellular shape and organizations.

    Cytoskeleton

  • 17

    Functions for ATP production

    Mitochondria

  • 18

    The following factors influence the diffusion rate of substances through a plasma membrane except?

    All of the above

  • 19

    Which of the following statements regarding the nucleus are true? 1. Nucleoli within the nucleus are the sites of ribosome synthesis. 2. Most of the cell’s hereditary units, called genes, are located within the nucleus. 3. Proteins synthesis occurs within the nucleus. 4. In non-dividing cells, DNA is found in the nucleus in the form of chromatin.

    1, 2, 4

  • 20

    Stage when chromatin fibers condense and shorten to form chromosomes

    Prophase

  • 21

    Which one of the following types of bonds is covalent?

    Disulfide

  • 22

    What is the pH of a solution containing 0.2 M acetic acid (pKa=4.7) and 0.1 M sodium acetate?

    5.4

  • 23

    A weak acid HA, has a pKa of 5.0. If 1.0 mol of this acid and 0.1 mol of NaOH were dissolved in one liter of water, what would the final pH be?

    4.05

  • 24

    All of the following are true regarding vital force theory except:

    Urea can be synthesized from simple inorganic compounds.

  • 25

    15. A patient seen in the ER has ingested antifreeze in a suicide attempt. Other than bicarbonate, which one of the following is the major buffer of acids to help maintain the pH in the blood within the range compatible with life?

    Hemoglobin

  • 26

    The functional group that help stabilize the shape of proteins.

    –SH

  • 27

    Organic compounds that function primarily to provide a readily available source of chemical energy to generate the ATP that drives metabolic reactions are:

    Carbohydrates

  • 28

    The body’s most highly concentrated form of chemical energy is

    Triglyceride

  • 29

    The disaccharide maltose is formed by combining what monosaccharides?

    Glucose + glucose

  • 30

    The disaccharide sucrose is formed by combining what monosaccharides?

    Glucose + fructose

  • 31

    When proteins are heated or pH is changed, their tertiary structure is ruptured and it loses biological activity. This process is called _________________.

    Denaturation

  • 32

    Lipid and protein particles that are bonded together to make lipid more water soluble is termed as _______________.

    Lipoproteins

  • 33

    Type of protein structure, which have the unique sequence of amino acids that are linked by covalent peptide bonds.

    Primary structure

  • 34

    Which of the following structures is a 20:2 (Δ4,9) fatty acid?

    CH3(CH2)2CH=CH(CH2)3CH=CH(CH2)9COOH

  • 35

    Which of the following statements is not true concerning DNA?

    It is composed of a single strand of nucleotides.

  • 36

    All of the following are Nonpolar, aliphatic amino acids except

    Serine

  • 37

    Which of the following is not an essential amino acid?

    Proline

  • 38

    Of the 20 standard amino acids, only ______________ is not optically active. The reason is that its side chain is ____________.

    Glycine: is a hydrogen atom

  • 39

    Which among the following is a non-essential amino acid?

    Serine

  • 40

    Peptide bond is a _________.

    Covalent bond

  • 41

    Which of the following statements is false?

    Secondary structure of a protein determines how it folds up into a unique three-dimensional structure.

  • 42

    Tertiary conformation of proteins is maintained by 3 types of bonds namely ionic, hydrogen and __________.

    Disulfide

  • 43

    Which of the following is true?

    The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine stabilizes protein tertiary structure.

  • 44

    In 3° structure of proteins, folding and shaping is done by __________.

    Hydrophobic interaction

  • 45

    β-pleated sheets are the examples of _________.

    Secondary structure

  • 46

    Which of the following are known as helix breakers?

    Proline and glycine

  • 47

    A process by which a protein structure assumes its functional shape or conformation is?

    Folding

  • 48

    Which of the following is true about Michaelis-Menten kinetics?

    It describes single substrate enzymes.

  • 49

    When the velocity of enzyme activity is plotted against substrate concentration, which of the following is obtained?

    Hyperbolic curve

  • 50

    The rate-determining step of Michaelis-Menten kinetics is __________.

    The complex dissociation step to produce products.

  • 51

    What is the general mechanism of an enzyme?

    It acts by reducing the activation energy.

  • 52

    The allosteric inhibitor of an enzyme ___________.

    Participates in feedback regulation.

  • 53

    In the case of allosteric enzymes what is the graphical representation when initial velocity is plotted against substrate concentration?

    Sigmoid curve

  • 54

    Which is the enzyme that acts as a regulatory enzyme in a four-step metabolic pathway?

    First enzyme

  • 55

    A certain enzyme will hydrolyze egg white but not starch. Which statement best explains this observation?

    Enzyme molecules are specific in their actions.

  • 56

    The red precipitate formed when glucose is heated with “Benedict’s reagent” is

    Cuprous oxide

  • 57

    Fructose and Glucose can be distinguished by ___________

    Seliwanoff’s test

  • 58

    Which of the following is an example of monosaccharide?

    Galactose

  • 59

    In which of the following forms, glucose is stored in plants?

    Starch

  • 60

    In maltose, between which of the following carbons there is a linkage?

    C1, C4

  • 61

    The following structure is what carbohydrate?[object Object]

    β-D-glucose

  • 62

    Breakdown of glycogen to glucose in an example of

    Catabolism

  • 63

    Which of the following carbohydrates is a triose?

    Glyceraldehyde

  • 64

    Which of the following are found in connective tissues?

    Glycosaminoglycan

  • 65

    Which of the following enzyme catalyzes the first step of glycolysis?

    Hexokinase

  • 66

    What is the general term used for the anaerobic degradation of glucose to obtain energy?

    Fermentation

  • 67

    Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?

    Phosphofructokinase-1

  • 68

    Which one of the following metabolites is used by all cells for glycolysis, glycogen synthesis, and the hexose monophosphate shunt pathway?

    Glucose-6-phosphate

  • 69

    After digestion of a piece of cake that contains flour, milk, and sucrose as its primary ingredients, the major carbohydrate products entering the blood are which one of the following? Choose the one best answer.

    Glucose, fructose, and galactose

  • 70

    Glycolysis converts ___________

    Glucose into pyruvate

  • 71

    In the pentose phosphate pathway, the major products are ____________.

    Ribulose and NADPH

  • 72

    What is the first reaction of the pentose phosphate pathway?

    Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone.

  • 73

    The pentose-phosphate pathway generates which one of the following?

    Xylulose-5-phosphate by one of the oxidative reactions.

  • 74

    Which one out of the following enzymes acts in the pentose phosphate pathway?

    6-phosphogluconate dehydrogenase

  • 75

    Oxidation of 3 molecules of glucose by pentose phosphate pathway results in the production of ____________.

    3 molecules of pentose, 6 molecules of NADPH and 3 molecules of CO2

  • 76

    Which one of the following statements is correct about the pentose phosphate pathway?

    It generates 6 moles of CO2 for each mole of glucose consumed.

  • 77

    Thiamine pyrophosphate is a coenzyme of what enzyme?

    Transketolase

  • 78

    Conversion of xylulose 5-phosphate to ribulose 5-phosphate is catalyzed by ___________.

    Phosphopentose epimerase

  • 79

    Which of the following statements is correct about the reductive pentose phosphate pathway?

    Transaldolase transfers 2 carbon units.

  • 80

    The use of NADPH generated from pentose phosphate pathway cannot be ____________.

    Oxidized in the electron transport chain to provide 38 ATPs.

  • 81

    The deficiency of which of the following enzyme leads to galactosemia?

    Galactokinase

  • 82

    The conversion of which of the following involves two nucleotide derivatives?

    Galactose 1-phosphate to glucose 1-phosphate

  • 83

    A 4-week-old baby is being seen by the pediatrician because of frequent vomiting after meals and tenderness in the abdomen. Upon examination, the physician noted an enlarged liver and a hint of cataract formation in both of the child’s eyes. A urine dipstick test for a reducing sugar gave a positive result. Blood glucose levels were slightly below normal. The compound that reacted with the urine dipstick test was most likely which one of the following?

    Galactose

  • 84

    Which of the following enzyme is responsible for the conversion of glucose 1-phosphate to glucose 6- phosphate?

    Phosphoglucomutase

  • 85

    The enzyme responsible for the conversion of galactose to galactitol.

    Aldose reductase

  • 86

    Glucagon and epinephrine stimulate glycogen breakdown to glucose 6-phosphate ________.

    Indirectly by first stimulating adenylate cyclase to make cAMP.

  • 87

    Glucagon is released from ___________.

    Pancreas

  • 88

    Glucose 6-phosphatase is present only in ___________.

    Liver

  • 89

    In glycogen degradation, the enzyme responsible to convert glycogen to glucose 1-phosphate is

    Glycogen phosphorylase

  • 90

    During meal (therefore, in a non-fasting state), blood glucagon is ________, while blood insulin is ____________.

    Decreased; increased

  • 91

    In relation to question number 5, in a non-fasting state, glycogen degradation is __________ while glycogen synthesis is ______________.

    Decreased; increased

  • 92

    This is the glycogen storage disease wherein there is deficiency of the glycogen branching enzyme, transglucosidase.

    Type IV

  • 93

    The Andersen disease, which is an example of GSD, is caused by the deficiency of what enzyme? Glucosyl 4:6 transferase

    Glucosyl 4:6 transferase

  • 94

    In the liver, during glycogen degradation, the enzyme phosphoglucomutase converts ______________.

    Glucose 1-phosphate to glucose 6-phosphate

  • 95

    Which of the following is INCORRECTLY matched?

    Type VI: McArdle