ACS part 2
問題一覧
1
The amount of blood pumped from the left ventricle/min, Adult CO range is 4-7 L/min, IS dependent on the relationship of the HR and SV (stroke volume), CO= HR x SV
2
The number of times the ventricles contract per minute, Normal adult resting HR is 60-100 bpm, Is controlled by automnomic nervous system, Adjusts rapidly to regulate cardiac output
3
The amount of volume ejected by the LEFT ventricle during SYTOLE, IS influence by HR, preload, and afterload, and contractility
4
The amount of blood ejected blood ejected by the Left ventricle expressed in a percentage, Normal is 50-70%
5
Afterload
6
The degree of myocardial fiber stretch at the end of diastole AND its ability to “shrink to squeeze” back, Determined by left ventricular end-diastolic volume (LVEDV), Starling’s law: the more the heart is filled during diastole the more forcefully it contracts (up to a point), Excessive filling = excessive LVDEV = overstretched = decreased CO
7
The pressure ventricles must overcome to eject blood into the peripheral blood vessels, Is influenced by the condition of the aortic valve, Is also influenced by pressure and distensibility of the vascular system
8
Force of cardiac contraction independent of preload, How well does it “squeeze”
9
ST-elevation myocardial infarction, ST segment elevation greater than 1mm or more in 2 or more contiguous ECG leads
10
O2 @ 4L/min if O2<94%, Aspirin 160mg to 325mg chew, Nitroglycerin SL or spray x3, Give morphine for pain
11
Action binds with mu and kappa pain receptors to produce analgesia, is a venodilator, Dosing 2-4mg IV q5-15min (up to 8mg can be used), Adverse effects respiratory depression, Contratindicated in hypotension or hypovolemia
12
ST segment elevation greater than 1mm or more in 2 or more contiguous ECG leads, Large occlusion, Rapid reperfusion required
13
Targeted H&P, Blood work, CXR, Total ED time should be <30mins, Timely reperfusion: Percutaneous coronary intervention -within 90 minutes first contact -within 30 minutes of EC door, Fibroinolytics -within 30 minutes of EC door
14
Is superior to fibronolytics if performed by skilled providers (40 facilities in MI), Door to balloon time should be less than or equal to 90 mins, Preferred if heart failure or cardiog, Caution if: Allergy to contrast, metformin hydrochloride, renal impairment, anticoagulants. (keep in mind this isn’t a contraindication but a caution!)
15
A balloon-tipped catheter is inserted into a blood vessel and guided to the narrowed section of the coronary artery., The uninflated balloon is positioned at the site of the blockage or plaque build-up., The balloon is then inflated, which compresses the plaque against the artery wall, effectively widening the artery., After the artery is widened, the balloon is deflated and removed, leaving the artery open to restore proper blood flow.
16
A type of reperfusion therapy, Used to dissolve blood clots in the coronary arteries and restore blood flow during conditions like ST-elevation MI STEMI.
17
Action: dissolves clots in coronary arteries to restore blood flow helping reduce damage to the heart muscle, Indications: Primarily used for STEMI if onset of symptoms is less than 12 hours, Indications: Early treatment is ideal, Indicaitons: The goal is to administe fibrinolyticsa within 30 minutes of the pt arriving at the hospital (door-to-needle time)
18
Absolute contraindications: Recent major bleeding, pregnancy, Relative contraindications: HTN with SBP>180 or DBP>110
19
rtPA (activase), Retelplase (Retavase), Tenecteplase (TNKase), SE: bleeding
20
Action: Binds to P2Y12 receptors blocking ADP thus reducing platelet function, Uses: Decreases sudden cardiac death due to thrombus
21
Cautions: Age>75, hx CVA, stop 7 days before surgery, ALERT: Cardiologist approval is needed to stop therapy.
22
Examples: Clopidogrel (Plavix) -on for 2 yrs Prasugrel (Effient) Tricagrelor (brilinta) -is newer less SE, pricey, off in a year sometimes months Cangrelor (Kangreal), SE: Bleeding, Stroke
23
Facto xa
24
Deliberate reduction of the core body temperature usually around 32-34C in pts who don’t regain consciousness after ROSC following a cardiac arrest, Only intervention shown to improve neurological outcome and decrease mortality, Adverse effects: F&E imbalance, arrhythmias, insulin resistance, shivering, coagulation problems, pain & sedation concerns
25
Non st elevation myocardial infarction, Chest pain, ST depression ≥ 0.5mm, T wave inversion, Transient (<20 min) ST elevation, Cardiac markers (Troponin) determine diagnosis
26
911- EMS, Aspirin 162-325mg,, Antiplatelet (clopidogrel), Nitroglycerin sublingual, O2, IV, Heart monitor, morning, ECG, H&P, Blood draw: cardiac biomarker
27
Bedrest, Oxygen, Nitroglycerin, Beta blocker, Calcium channel blocker, ACE inhibitor or angiotensin receptor blocker
28
Chest pain, Hypertension, Pulmonary edema, Titrate to response parameters: SBP >100 (with IV, without would be 120), Titrate to response parameters: Limit BP drop 20-30mmhg
29
Slow release, Squeeze a ribbon of ointment onto measuring paper, Apply to upper torso
30
Indirectly inhibits thrombin, Bolus IV then continuous infusion to maintain a therapeutic PTT/aPTT (2-3x normal), Low intensity 55-75 seconds/60-80, High intensity 80-100, Normal PTT 25-30 (3x norm for heparin) Critical >120, Normal aPTT 22-31 (3x normal for heparin? Critcial >120, Monitor platelets - risk of HIT
31
Enoxaparin (Lovenox), Bivalrudin (Angiomax), Argatroban (Acova), Fondaparinus (Arixta)
32
Next day or earlier if:, :Persistent pain, :Ventricular dysrythmias, :Intermittent ST changes, :Symptoms of heart failure
33
Inhibits platelet aggregation by preventing fibrin binding with platelets
34
UA/NSTEMI, STEMI abciximab only, In combination with aspirin herparin and clopidogrel before PCI, Not indicated if PCI not planned
35
Eptifibatide (Integrilin), Abciximab (ReoPro, Tirofibran (Aggrastat), Bleeding
36
Acute pain, Ineffective cardiopulmonary tissue perfusion, Ineffective coping, Activty intolerance, RC dysthymias, RC heart failure, RC Reccurrent chest discomfort and extension of injury.
37
Related to effect of acute illness, major changes in lifestyle &/or loss of control over body part, Outcomes: Patient will indicate a reduction in anxiety and recognize the beginning of control over life, General interventions: Assess level of anxiety Allow expression of feelings Repeat explanations in simple terms Anxiolytic
38
Deinal: Avoids discussing what happened, may or may not comply with treatment, Denial nursing interventions: Remain calm, avoid threats while indicating harmful behavior, Anger: an attempt to regain control, Anger Nursing interventions: Allow verbalizaiton, allow opportunities to make decisions, Depression: Grief response, Depression nursing interventions: listen no false reassurances, encourage ADL, teaching
39
Patients with high levels of optimism experience better long term (>12 months) physical health and psychological well being, Significantly less readmisssions, More l healthy lifestyle changes: Smoking cessation More fruits and veggies
40
Planned cardiac rehabilitation:, :Phase 1: hospitalization -Nursing & Physical therapy supervised progressive ambulation, :Phase 2: Convalescense -Outpatient cardiac rehab, :Phase 3: Long term conditioning -Independent, Studies have shown 12 sessions ⬆️ survival 24 sessions has the greatest impact decreasing risk of death by 50% and risk of MI BY 33%!!, every person who has a heart attack should have cardiac rehab!
41
Inferior -Bradcardias -Blocks, Anterior -Ventricular irritability -BBB
42
B blockers, Inotropes, ACE-I or ARBs, Balloon pump
43
Smoking cessation, Cardiac diet, Statin, Risk factor modification, Exercise, Sexual activity, Blood pressure control, Blood glide control, Manage angina, Rest, Nitrates, Beta Blockers, Ca channel blockers, Revascularization
44
Postop care:, Manage F&E balance, Complications- hypotension, hypothermia, hypertension, bleeding, cardiac tamponade, change LOC
45
Home care management (support groups), Self-management education: Risk factor modification Complementary and integrative health Sexual activity Drug therapy Seeking medical assistance, Healthare resources: American heart association Mended hearts
46
State pain is alleviated, Have adequate myocardial perfusion, Be free of complications such as dysthymias and heart failure, Sexual activity is an important component of patient and partner quality of life, and it is reasonable for most patients with CVD to engage in sexual activity.
47
Ok great thanks!
48
Aspirin -at arrival -RX at d/c, Statin, LV function evaluation, ACE-I or ARB, Reperfusion therapy -Fibrinolytics in 30 mins -PCI in 90 mins, Transfer for PCI in 24 hrs, Smoking cessation, Cardiace rehab referral, Cholesterol assessment, Appropriate anticoagulant dosin, Appriopraite fibrinolytic dosing, Clopidogrel or prasurgel or ticagrelor
49
Deaths occur in pts with non-critical disease, -Unstable plaque, -Abnormal coronary flow reserve
50
Atheroscelrosis
51
Anterior wall
52
The patient is experiencing an NTSEMI
53
12 lead EKD, Echo, Troponin
54
2a - Heart failure, 2b- Cardiac muscle damage acute mi necrosis
55
Atenolol, Morphine, Furosemide
56
PTCA percutaneous transluminal coronary angioplasty with coronary artery stent placement
57
Diet changes, exercise, smoking cessation, medication therapy
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45問 • 1年前問題一覧
1
The amount of blood pumped from the left ventricle/min, Adult CO range is 4-7 L/min, IS dependent on the relationship of the HR and SV (stroke volume), CO= HR x SV
2
The number of times the ventricles contract per minute, Normal adult resting HR is 60-100 bpm, Is controlled by automnomic nervous system, Adjusts rapidly to regulate cardiac output
3
The amount of volume ejected by the LEFT ventricle during SYTOLE, IS influence by HR, preload, and afterload, and contractility
4
The amount of blood ejected blood ejected by the Left ventricle expressed in a percentage, Normal is 50-70%
5
Afterload
6
The degree of myocardial fiber stretch at the end of diastole AND its ability to “shrink to squeeze” back, Determined by left ventricular end-diastolic volume (LVEDV), Starling’s law: the more the heart is filled during diastole the more forcefully it contracts (up to a point), Excessive filling = excessive LVDEV = overstretched = decreased CO
7
The pressure ventricles must overcome to eject blood into the peripheral blood vessels, Is influenced by the condition of the aortic valve, Is also influenced by pressure and distensibility of the vascular system
8
Force of cardiac contraction independent of preload, How well does it “squeeze”
9
ST-elevation myocardial infarction, ST segment elevation greater than 1mm or more in 2 or more contiguous ECG leads
10
O2 @ 4L/min if O2<94%, Aspirin 160mg to 325mg chew, Nitroglycerin SL or spray x3, Give morphine for pain
11
Action binds with mu and kappa pain receptors to produce analgesia, is a venodilator, Dosing 2-4mg IV q5-15min (up to 8mg can be used), Adverse effects respiratory depression, Contratindicated in hypotension or hypovolemia
12
ST segment elevation greater than 1mm or more in 2 or more contiguous ECG leads, Large occlusion, Rapid reperfusion required
13
Targeted H&P, Blood work, CXR, Total ED time should be <30mins, Timely reperfusion: Percutaneous coronary intervention -within 90 minutes first contact -within 30 minutes of EC door, Fibroinolytics -within 30 minutes of EC door
14
Is superior to fibronolytics if performed by skilled providers (40 facilities in MI), Door to balloon time should be less than or equal to 90 mins, Preferred if heart failure or cardiog, Caution if: Allergy to contrast, metformin hydrochloride, renal impairment, anticoagulants. (keep in mind this isn’t a contraindication but a caution!)
15
A balloon-tipped catheter is inserted into a blood vessel and guided to the narrowed section of the coronary artery., The uninflated balloon is positioned at the site of the blockage or plaque build-up., The balloon is then inflated, which compresses the plaque against the artery wall, effectively widening the artery., After the artery is widened, the balloon is deflated and removed, leaving the artery open to restore proper blood flow.
16
A type of reperfusion therapy, Used to dissolve blood clots in the coronary arteries and restore blood flow during conditions like ST-elevation MI STEMI.
17
Action: dissolves clots in coronary arteries to restore blood flow helping reduce damage to the heart muscle, Indications: Primarily used for STEMI if onset of symptoms is less than 12 hours, Indications: Early treatment is ideal, Indicaitons: The goal is to administe fibrinolyticsa within 30 minutes of the pt arriving at the hospital (door-to-needle time)
18
Absolute contraindications: Recent major bleeding, pregnancy, Relative contraindications: HTN with SBP>180 or DBP>110
19
rtPA (activase), Retelplase (Retavase), Tenecteplase (TNKase), SE: bleeding
20
Action: Binds to P2Y12 receptors blocking ADP thus reducing platelet function, Uses: Decreases sudden cardiac death due to thrombus
21
Cautions: Age>75, hx CVA, stop 7 days before surgery, ALERT: Cardiologist approval is needed to stop therapy.
22
Examples: Clopidogrel (Plavix) -on for 2 yrs Prasugrel (Effient) Tricagrelor (brilinta) -is newer less SE, pricey, off in a year sometimes months Cangrelor (Kangreal), SE: Bleeding, Stroke
23
Facto xa
24
Deliberate reduction of the core body temperature usually around 32-34C in pts who don’t regain consciousness after ROSC following a cardiac arrest, Only intervention shown to improve neurological outcome and decrease mortality, Adverse effects: F&E imbalance, arrhythmias, insulin resistance, shivering, coagulation problems, pain & sedation concerns
25
Non st elevation myocardial infarction, Chest pain, ST depression ≥ 0.5mm, T wave inversion, Transient (<20 min) ST elevation, Cardiac markers (Troponin) determine diagnosis
26
911- EMS, Aspirin 162-325mg,, Antiplatelet (clopidogrel), Nitroglycerin sublingual, O2, IV, Heart monitor, morning, ECG, H&P, Blood draw: cardiac biomarker
27
Bedrest, Oxygen, Nitroglycerin, Beta blocker, Calcium channel blocker, ACE inhibitor or angiotensin receptor blocker
28
Chest pain, Hypertension, Pulmonary edema, Titrate to response parameters: SBP >100 (with IV, without would be 120), Titrate to response parameters: Limit BP drop 20-30mmhg
29
Slow release, Squeeze a ribbon of ointment onto measuring paper, Apply to upper torso
30
Indirectly inhibits thrombin, Bolus IV then continuous infusion to maintain a therapeutic PTT/aPTT (2-3x normal), Low intensity 55-75 seconds/60-80, High intensity 80-100, Normal PTT 25-30 (3x norm for heparin) Critical >120, Normal aPTT 22-31 (3x normal for heparin? Critcial >120, Monitor platelets - risk of HIT
31
Enoxaparin (Lovenox), Bivalrudin (Angiomax), Argatroban (Acova), Fondaparinus (Arixta)
32
Next day or earlier if:, :Persistent pain, :Ventricular dysrythmias, :Intermittent ST changes, :Symptoms of heart failure
33
Inhibits platelet aggregation by preventing fibrin binding with platelets
34
UA/NSTEMI, STEMI abciximab only, In combination with aspirin herparin and clopidogrel before PCI, Not indicated if PCI not planned
35
Eptifibatide (Integrilin), Abciximab (ReoPro, Tirofibran (Aggrastat), Bleeding
36
Acute pain, Ineffective cardiopulmonary tissue perfusion, Ineffective coping, Activty intolerance, RC dysthymias, RC heart failure, RC Reccurrent chest discomfort and extension of injury.
37
Related to effect of acute illness, major changes in lifestyle &/or loss of control over body part, Outcomes: Patient will indicate a reduction in anxiety and recognize the beginning of control over life, General interventions: Assess level of anxiety Allow expression of feelings Repeat explanations in simple terms Anxiolytic
38
Deinal: Avoids discussing what happened, may or may not comply with treatment, Denial nursing interventions: Remain calm, avoid threats while indicating harmful behavior, Anger: an attempt to regain control, Anger Nursing interventions: Allow verbalizaiton, allow opportunities to make decisions, Depression: Grief response, Depression nursing interventions: listen no false reassurances, encourage ADL, teaching
39
Patients with high levels of optimism experience better long term (>12 months) physical health and psychological well being, Significantly less readmisssions, More l healthy lifestyle changes: Smoking cessation More fruits and veggies
40
Planned cardiac rehabilitation:, :Phase 1: hospitalization -Nursing & Physical therapy supervised progressive ambulation, :Phase 2: Convalescense -Outpatient cardiac rehab, :Phase 3: Long term conditioning -Independent, Studies have shown 12 sessions ⬆️ survival 24 sessions has the greatest impact decreasing risk of death by 50% and risk of MI BY 33%!!, every person who has a heart attack should have cardiac rehab!
41
Inferior -Bradcardias -Blocks, Anterior -Ventricular irritability -BBB
42
B blockers, Inotropes, ACE-I or ARBs, Balloon pump
43
Smoking cessation, Cardiac diet, Statin, Risk factor modification, Exercise, Sexual activity, Blood pressure control, Blood glide control, Manage angina, Rest, Nitrates, Beta Blockers, Ca channel blockers, Revascularization
44
Postop care:, Manage F&E balance, Complications- hypotension, hypothermia, hypertension, bleeding, cardiac tamponade, change LOC
45
Home care management (support groups), Self-management education: Risk factor modification Complementary and integrative health Sexual activity Drug therapy Seeking medical assistance, Healthare resources: American heart association Mended hearts
46
State pain is alleviated, Have adequate myocardial perfusion, Be free of complications such as dysthymias and heart failure, Sexual activity is an important component of patient and partner quality of life, and it is reasonable for most patients with CVD to engage in sexual activity.
47
Ok great thanks!
48
Aspirin -at arrival -RX at d/c, Statin, LV function evaluation, ACE-I or ARB, Reperfusion therapy -Fibrinolytics in 30 mins -PCI in 90 mins, Transfer for PCI in 24 hrs, Smoking cessation, Cardiace rehab referral, Cholesterol assessment, Appropriate anticoagulant dosin, Appriopraite fibrinolytic dosing, Clopidogrel or prasurgel or ticagrelor
49
Deaths occur in pts with non-critical disease, -Unstable plaque, -Abnormal coronary flow reserve
50
Atheroscelrosis
51
Anterior wall
52
The patient is experiencing an NTSEMI
53
12 lead EKD, Echo, Troponin
54
2a - Heart failure, 2b- Cardiac muscle damage acute mi necrosis
55
Atenolol, Morphine, Furosemide
56
PTCA percutaneous transluminal coronary angioplasty with coronary artery stent placement
57
Diet changes, exercise, smoking cessation, medication therapy