Inflammation

23問 • 9ヶ月前

問題一覧

What term describes a fluid due to an inflammatory response, may contain cells, and high specific gravity?

Exudate

During a typical inflammatory response, what is the predominant leukocyte cell type present in the inflamed tissue at 48hrs after initial injury?

Macrophages

Which statements regarding the role of the extracellular matrix in inflammation are correct? 1. It is a chemoattractant 2. It is a substratum to which leukocytes can adhere 3. It replaces necrotic tissue 4. It sequesters water 5. It is produced by macrophages

2, 3, 4

Which of the following molecules acts as an opsonin?

C3b

Leukocytes perform phagocytosis to remove foreign particles. What is the correct sequence of the following events? 1. Engulfment of particle 2. Degradation of ingested particle 3. Formation of phagosomes 4. Formation of phagolysosome 5. Recognition and attachment of particle

5-1-3-4-2

Of the following five attributes, which THREE are features of leukocyte chemotaxis? 1. Induced by bacterial products 2. Mediated by contractile elements which assemble due to increased cytosolic Ca2+ 3. Very slow process 4. Mediated by binding of chemokine to leukocyte receptor 5. Mediated by cell-cell binding

1, 2, 4

Cytokines, including TNF-beta and IL-1, induce systemic effects of inflammation. Which of the following statements about the systemic effects of inflammation is correct?

Systemic effects of inflammation can include pyrexia and shivering

Leukocytes have several mechanisms by which they can destroy or remove microbes. Which of the following is NOT one of these mechanisms?

Frustrated phagocytosis

Macrophages are the most important cells in chronic inflammation. Which of the functional properties listed below are characteristic for macrophages? 1. Phagocytic activity 2. In blood as terminally differentiated cells 3. Mitotically active 4. Activation in tissues

1, 3, 4

Which of the following statements best explains complete resolution of an acute inflammatory response?

The usual outcome of a limited or short-lived injury

Scar tissue in the skin differs from healthy skin. How do these differences appear histologically? 1. Old scars contain very few blood vessels 2. Scars exhibit multifocal plasma cell accumulations 3. Abundant dense collagen fibre bundles are seen 4. The tissue exhibits a variable degree of interstitial oedema 5. A scar in the skin is hairless

1, 3, 5

Following injury, a tissue may repair by regeneration or by connective tissue (fibrosis). Regarding tissue repair, which of the following statements is correct?

Repair by fibrosis occurs if the structural framework of a tissue is destroyed

An injury that results in parenchymal cell death, but the tissue framework remains intact, is most likely to result in…

Regeneration + restitution of normal tissue structure

An injury that is characteried by persistent tissue damage in an organ, is most likely to result in…

Fibrosis

An injury that is characterised by highly vascular, friable tissue, is composed ofthat is characterised by highly vascular, friable tissue, is composed of…

Haematoma

An injury that is caused by the presence of a foreign body, is likely to be dominated by…

Granulomatous inflammation

What is the definition of abscess?

Accumulation of pus within a cavity which developed due to tissue necrosis.

Q. Which of the following statements are TRUE? 1. A granuloma is a focal area of granulomatous inflammation 2. A granuloma may contain multinucleated giant cells 3. A granuloma is an acute inflammatory process 4. A granuloma may be the result of the reaction to a foreign body 5. A granuloma has a central core of neutrophils

1, 2, 4

This question is about wounds in the skin, and factors that need to be considered when they are managed/treated. Which of the following statements about healing by second intention are true? 1. They can be caused by infarction 2. Wound contraction may occur 3. They can be closed surgically 4. The nutritional status of the patient will not affect the healing of the wound 5. They are more prone to secondary infection or contamination

1, 2, 5

This is derived from serum protein and forms a fine meshwork in an acute inflammatory response

Fibrin

This is a protein secreted by fibroblasts in chronic inflammation…

Collagen

This is the highly vascular tissue that fills a deficit in a tissue following necrosis…

Granulation tissue

These are multinucleated cells derived from macrophages…

Giant cells