1. A patient with hemolytic anemia will

2. W/c of the ff elevates carboxyhemoglobin?

3. Serum "anion gap" is ↑ in patients with:

4. Fasting serum phosphate concentration is controlled primarily by the:

5. Urobilinogen is formed in the:

6. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the:

7. Most automated blood gas analyzers directly measure:

8. A salicylate level is performed to detect toxicity caused by ingestion of excess:

9.W/c of the ff amino acids is asso w/ sulfhydryl grp?

10. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and:

11. In the Malloy & Evelyn method for the determination of serum bilirubin concentration, quantitation is obtained by measuring the green color of:

12. The solute that contributes the most to the total serum osmolality is:

13. A px is admitted w/ biliary cirrhosis. If a serum protein electrophoresis is performed which of the ff globulin fractions will be most often be elevated?

14. The biologically most active and naturally occurring androgen is:

15. The preparation of a patient for standard glucose tolerance testing should include:

16. An increase in serum acetone is an indicative of a defect in metabolism of:

17. 45yo woman complains of fatigue, heat intolerance, & hair loss. Total & FT4 are abnormally ↓. If the TSH showed marked elevation, this would be consistent with:

18. The most specific enzyme test for acute pancreatitis:

19. A 3yo child was evaluated for abdominal pain and anorexia by a physician. A CBC revealed a hgb of 9.8 g/dL and basophilic stippling of the RBCs. The doctor should order further tests to check for poisoning from:

20. The substance that is measured to estimate the serum concentration of TAG by most methods is:

21. Most chemical methods for determining total protein utilize which of the following reactions?

22. A 1-year-old girl with a hyperlipoproteinemia & lipoprotein lipase deficiency has the ff lipid profile: Cholesterol: 300mg/dL(7.77mmol/L) LDL: ↑ HDL: ↓ triglyceride:1200mg/dL(13.56mmol/L) Chylomicrons: present A serum spx from this px that was refrigerated overnight would most likely be:

23.Most of the CO2 present in blood is in the form of:

24. When performing a manual protein analysis on a xanthochromic spinal fluid, the technician should:

25. Blood was collected in a serum separator tube on a px who has been fasting since midnight. The time of collection was 7 am. The laboratory test which should be recollected is:

26.Lithium therapy is widely used in the treatment of:

27. Which of the following would be an example of a glucose-specific colorimetric method?

28. The majority of thyroxine is converted into the more biologically active hormone:

29. Which of the following enzymes catalyzes the conversion of starch to glucose and maltose?

30. Amperometry is the principle of the:

31. Which of the following methods for quantitation of HDL is most suited for clinical laboratory use?

32. A condition in which erythrocyte protoporphyrin is increased is:

33. In spectrophotometric determination, w/c of the ff is the formula for calculating the absorbance of a soln?

34 Which of the following enzymes of heme biosynthesis is inhibited by lead?

35. Which of the ff serum protein fractions is most likely to be elevated in px with nephrotic syndrome?

36. Plasma for cortisol determinations were collected at 7am, after waking the px, & at 10pm that evening. The cortisol level of the morning spx was higher than the evening sample. This is consistent with:

37. During a normal pregnancy, quantitative HCG levels peak how many weeks after the last menstrual period?

38. Which of the ff steroids is an adrenal cortical hormone?

39. Beriberi is associated with deficiency of vitamin:

40. The most common form (95%) of congenital adrenal hyperplasia is 21-hydroxylase deficiency, which is detected by elevated plasma:

41. Rickets is associated with a deficiency of which of the following vitamins?

42. Aspartate aminotransferase(AST) is characteristically elevated in diseases of the:

43.W/c of the ff glycosylated Hgb is recommended by the ADA guidelines for testing diabetic px?

44. A diagnosis of primary adrenal insufficiency requires demonstration of:

45. Specimens for blood gas determination should be drawn into a syringe containing:

46. Stray light can be detected in a spectrophotometer by utilizing a:

47. presence of CRP in the blood is an indication of:

48. What is the proper pH for the buffered solution used to perform serum protein electrophoresis

49. The function of serum albumin in the peripheral blood is to:

50. In a specimen collected for plasma glucose analysis, sodium fluoride:

51. The screen for adrenal cortical hyperfunction with the greatest sensitivity and specificity is:

52. Which of the following represents the end product of purine metabolism in humans?

53. Analysis of CSF for oligoclonal bands is used to screen for which of the following disease states?

54. A reciprocal relationship exists between:

55. The hormone that triggers ovulation is:

56. What common substrate is used in the biosynthesis of adrenal steroids including Androgens and Estrogens?

57. Valinomycin enhances the selectivity of the electrode used to quantitate:

58. The principle excretory form of nitrogen is/are:

59. Blood received in the laboratory for blood gas analysis must meet which of the ff requirements?

60.What is the best method to diagnose lactase deficiency?

61.Hydrogen ion concentration (pH) in blood is determined by means of w/c of the ff electrodes?

62. The most widely used methods for bilirubin measurement are those based on the:

63. Phenobarbital is a metabolite of:

64. Kernicterus is an abn accumulation of bilirubin in:

65. After a difficult venipuncture requiring prolonged application of the tourniquet, the serum K+ was fount to be 6.8 mEq/L (6.8 mmol/L). The best course of action is to:

66. In addition to carcinoma of the prostate, elevated PSA can occur due to:

67. TIBC measures the serum iron transporting capacity of:

68. The urinary excretion product measured as an indicator of epinephrine production is:

69. Coulometry is often used to measure:

70. Pregnant woman w/ symptoms of thirst, frequent urination or unexplained weight loss should have which of the following tests performed?

71. Which one of the ff values obtained during a glucose tolerance test are diagnostic of DM?

72. At blood pH 7.40, what is the ratio of bicarbonate to carbonic acid?

73. 90% of the copper present in the blood is bound to

74. Cocaine is metabolized to:

75. Which of the following diseases results from a familial absence of high density lipoprotein?

76. CSF for glucose assay should be:

77. In familial hypercholesterolemia, the hallmark finding is an elevation of:

78. Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure:

79. When myocardial infarction occurs, the first enzyme to become elevated is:

80.W/c of the ff serum constituents is unstable if a 🩸 spx is left standing at RT for 8hr before processing?

81. The enzyme present in almost all tissues that may be separated by electrophoresis into 5 components is:

82. Given the following results: ALP-slight↑ AST-marked↑ ALT-marked↑ GGT-slight↑

83.osmol gap is defined as measured Osm/kg minus the calculated Osm/kg.Normally the osmol gap <:

84. Turbidity in serum suggests elevation of:

85. If the LDL-cholesterol is to be calculated by the Friedewald formula, what are the 2 measurements that need to be carried out by the same chemical procedure?

86.protein that has the highest dye-binding capacity:

87. A serum sample demonstrates an elevated result when tested with the Jaffe reaction. This indicates:

88. Which percentage of total serum calcium is nondiffusible protein-bound?

89. The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver metabolite of procainamide is often measured simultaneously?

90. Serum levels that define hypoglycemia in pre-term or low birth weight infants are:

91. Which of the ff substances is the biologically active precursor of a fat-soluble vitamin?

92. In the assay of LDH, which of the ff products is actually measured?

93. During pregnancy, the form of estrogen that predominates & may be useful in prenatal screening is:

94.A hospitalized px is experiencing ↑ neuromuscular irritability(tetany). W/c of the ff tests should be ordered immediately?

95. Severe diarrhea causes:

96. Absorption of vit B12 requires the presence of:

97. Isoenzyme assays are performed to improve:

98. To detect barbiturate abuse when analyzing urine specimens, immunoassay is the method of choice for screening. The method of choice for confirmation is:

99. Aldosterone is released by the adrenal cortex upon stimulation by:

⭐️100. A drug that relaxes the smooth muscles of the bronchial passages is: