72. At blood pH 7.40, what is the ratio of bicarbonate to carbonic acid?

59. Blood received in the laboratory for blood gas analysis must meet which of the ff requirements?

70. Pregnant woman w/ symptoms of thirst, frequent urination or unexplained weight loss should have which of the following tests performed?

79. When myocardial infarction occurs, the first enzyme to become elevated is:

73. 90% of the copper present in the blood is bound to

78. Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure:

36. Plasma for cortisol determinations were collected at 7am, after waking the px, & at 10pm that evening. The cortisol level of the morning spx was higher than the evening sample. This is consistent with:

52. Which of the following represents the end product of purine metabolism in humans?

9.W/c of the ff amino acids is asso w/ sulfhydryl grp?

⭐️100. A drug that relaxes the smooth muscles of the bronchial passages is:

45. Specimens for blood gas determination should be drawn into a syringe containing:

8. A salicylate level is performed to detect toxicity caused by ingestion of excess:

96. Absorption of vit B12 requires the presence of:

33. In spectrophotometric determination, w/c of the ff is the formula for calculating the absorbance of a soln?

77. In familial hypercholesterolemia, the hallmark finding is an elevation of:

37. During a normal pregnancy, quantitative HCG levels peak how many weeks after the last menstrual period?

18. The most specific enzyme test for acute pancreatitis:

16. An increase in serum acetone is an indicative of a defect in metabolism of:

32. A condition in which erythrocyte protoporphyrin is increased is:

31. Which of the following methods for quantitation of HDL is most suited for clinical laboratory use?

61.Hydrogen ion concentration (pH) in blood is determined by means of w/c of the ff electrodes?

15. The preparation of a patient for standard glucose tolerance testing should include:

2. W/c of the ff elevates carboxyhemoglobin?

87. A serum sample demonstrates an elevated result when tested with the Jaffe reaction. This indicates:

84. Turbidity in serum suggests elevation of:

86.protein that has the highest dye-binding capacity:

64. Kernicterus is an abn accumulation of bilirubin in:

41. Rickets is associated with a deficiency of which of the following vitamins?

58. The principle excretory form of nitrogen is/are:

11. In the Malloy & Evelyn method for the determination of serum bilirubin concentration, quantitation is obtained by measuring the green color of:

49. The function of serum albumin in the peripheral blood is to:

5. Urobilinogen is formed in the:

39. Beriberi is associated with deficiency of vitamin:

71. Which one of the ff values obtained during a glucose tolerance test are diagnostic of DM?

3. Serum "anion gap" is ↑ in patients with:

82. Given the following results: ALP-slight↑ AST-marked↑ ALT-marked↑ GGT-slight↑

50. In a specimen collected for plasma glucose analysis, sodium fluoride:

54. A reciprocal relationship exists between:

1. A patient with hemolytic anemia will

67. TIBC measures the serum iron transporting capacity of:

26.Lithium therapy is widely used in the treatment of:

66. In addition to carcinoma of the prostate, elevated PSA can occur due to:

20. The substance that is measured to estimate the serum concentration of TAG by most methods is:

57. Valinomycin enhances the selectivity of the electrode used to quantitate:

95. Severe diarrhea causes:

40. The most common form (95%) of congenital adrenal hyperplasia is 21-hydroxylase deficiency, which is detected by elevated plasma:

12. The solute that contributes the most to the total serum osmolality is:

14. The biologically most active and naturally occurring androgen is:

68. The urinary excretion product measured as an indicator of epinephrine production is:

51. The screen for adrenal cortical hyperfunction with the greatest sensitivity and specificity is:

85. If the LDL-cholesterol is to be calculated by the Friedewald formula, what are the 2 measurements that need to be carried out by the same chemical procedure?

76. CSF for glucose assay should be:

34 Which of the following enzymes of heme biosynthesis is inhibited by lead?

38. Which of the ff steroids is an adrenal cortical hormone?

90. Serum levels that define hypoglycemia in pre-term or low birth weight infants are:

19. A 3yo child was evaluated for abdominal pain and anorexia by a physician. A CBC revealed a hgb of 9.8 g/dL and basophilic stippling of the RBCs. The doctor should order further tests to check for poisoning from:

10. The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and:

30. Amperometry is the principle of the:

53. Analysis of CSF for oligoclonal bands is used to screen for which of the following disease states?

29. Which of the following enzymes catalyzes the conversion of starch to glucose and maltose?

91. Which of the ff substances is the biologically active precursor of a fat-soluble vitamin?

7. Most automated blood gas analyzers directly measure:

83.osmol gap is defined as measured Osm/kg minus the calculated Osm/kg.Normally the osmol gap <:

65. After a difficult venipuncture requiring prolonged application of the tourniquet, the serum K+ was fount to be 6.8 mEq/L (6.8 mmol/L). The best course of action is to:

56. What common substrate is used in the biosynthesis of adrenal steroids including Androgens and Estrogens?

81. The enzyme present in almost all tissues that may be separated by electrophoresis into 5 components is:

62. The most widely used methods for bilirubin measurement are those based on the:

88. Which percentage of total serum calcium is nondiffusible protein-bound?

92. In the assay of LDH, which of the ff products is actually measured?

55. The hormone that triggers ovulation is:

27. Which of the following would be an example of a glucose-specific colorimetric method?

89. The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver metabolite of procainamide is often measured simultaneously?

46. Stray light can be detected in a spectrophotometer by utilizing a:

44. A diagnosis of primary adrenal insufficiency requires demonstration of:

21. Most chemical methods for determining total protein utilize which of the following reactions?

75. Which of the following diseases results from a familial absence of high density lipoprotein?

23.Most of the CO2 present in blood is in the form of:

93. During pregnancy, the form of estrogen that predominates & may be useful in prenatal screening is:

60.What is the best method to diagnose lactase deficiency?

98. To detect barbiturate abuse when analyzing urine specimens, immunoassay is the method of choice for screening. The method of choice for confirmation is:

47. presence of CRP in the blood is an indication of:

99. Aldosterone is released by the adrenal cortex upon stimulation by:

43.W/c of the ff glycosylated Hgb is recommended by the ADA guidelines for testing diabetic px?

80.W/c of the ff serum constituents is unstable if a 🩸 spx is left standing at RT for 8hr before processing?

48. What is the proper pH for the buffered solution used to perform serum protein electrophoresis

42. Aspartate aminotransferase(AST) is characteristically elevated in diseases of the:

63. Phenobarbital is a metabolite of:

35. Which of the ff serum protein fractions is most likely to be elevated in px with nephrotic syndrome?

28. The majority of thyroxine is converted into the more biologically active hormone:

74. Cocaine is metabolized to:

94.A hospitalized px is experiencing ↑ neuromuscular irritability(tetany). W/c of the ff tests should be ordered immediately?

13. A px is admitted w/ biliary cirrhosis. If a serum protein electrophoresis is performed which of the ff globulin fractions will be most often be elevated?

69. Coulometry is often used to measure:

4. Fasting serum phosphate concentration is controlled primarily by the:

6. Regan isoenzyme has the same properties as alkaline phosphatase that originates in the:

17. 45yo woman complains of fatigue, heat intolerance, & hair loss. Total & FT4 are abnormally ↓. If the TSH showed marked elevation, this would be consistent with:

97. Isoenzyme assays are performed to improve:

22. A 1-year-old girl with a hyperlipoproteinemia & lipoprotein lipase deficiency has the ff lipid profile: Cholesterol: 300mg/dL(7.77mmol/L) LDL: ↑ HDL: ↓ triglyceride:1200mg/dL(13.56mmol/L) Chylomicrons: present A serum spx from this px that was refrigerated overnight would most likely be:

24. When performing a manual protein analysis on a xanthochromic spinal fluid, the technician should:

25. Blood was collected in a serum separator tube on a px who has been fasting since midnight. The time of collection was 7 am. The laboratory test which should be recollected is: