19.The ag marker most closely asso w/ transmissibility of HBV infection is:

100. What kind of ag-ab rxn would be expected if soluble antigen is added to homologous antibody?

51. Hep B, a dse arising from a DNA virus, is diagnosed in its acute phase via serology for HBsAg, HBeAg, IgM alpha-HBC and total alpha-HBc. Once a px reaches chronic HBV infxn, effectiveness of therapy may be evaluated using:

25. The ff cold agglutinin titer results are observed:

40. The J-chain is asso w/ w/c of the ff IG?

78.W/c of the ff has been asso w/ px who have homozygous C3 deficiency?

2. MHC class III genes code for

46. SLE px often have which of the ff test results?

52. The area of the IG molecule referred to as the hinge region is located between which domains?

41. Chronic transplant rejection is a cell mediated & humoral immune response that involves all the ff EXCEPT:

69.HLA-B8 ag has been asso w/ w/c of ff pairs of dse

13. Multiplex bead assays for the detection of cytokines are efficient quantifiers of numerous cytokines at one time. One complication of such testing is:

34. The strength of a visible reaction is known as:

26. On a follow-up visit to her dr, a young woman was given the results of her FTA-ABS test. She had been symptomatic for a couple months b4 this visit, w/ fever swollen cervical lymph nodes, fatigue,& rash affecting the palms of her hands & the soles of her feet,but she was now feeling better.Earlier test strategies that u would expect the dr. to have requested include all of the ff EXCEPT:

50. C3b and Fc receptors are present on:

74. A 16yo boy w/ infectious mononucleosis has a cold agglutinin titer of 1:2000. An important consideration of this antibody's clinical relevance is the:

96.W/c of the ff is the larger residual split portion of C3?

86.W/c of the ff IG is the most efficient at aggln?

93. Immunoassays are based on the principle of:

68. Macrophages are characterized by:

62. W/c of the ff is the most common humoral immune deficiency dse?

87. Antibody allotype is determined by the:

60. A px returns from a camping trip, where he vacationed for several days in a tick-endemic environment.1month after his return home, he visited his health care provider w/ complaints of fatigue, numbness & history of rash surrounding an insect bite that occurred immediately on his return home from vacation. Suspecting Lyme disease, his clinician ordered an ELISA to test for Lyme ab, results of w/c were equivocal on 2 diff tests. His health care provider then ordered follow-up testing with:

28. A px abnormal lymphocytes are CD2(+)ag, lack C3 receptors,& are surface IG(-) This can be classified as a disorder of:

31. In indirect ELISA mtd designed to detect ab to the rubella virus in px serum the conjugate used should be:

47.Mantoux skin test to identify infxn w/ M. tuberculosis

22. The hyperviscosity syndrome is most likely to be seen in monoclonal dse of which of the ff IG classes?

5. A heterophile antigen is best described as?

53. Biological false(+)VDRL rxn are frequently encountered in px with:

70.W/c test is used to evaluate cellular immune system in a px?

42. serological test that can be modified to selectively detect only specific IgM ab in untreated serum is:

18. MHC class I includes which peptides / proteins?

73.Anti-phospholipid ab asso w/ autoimune disorders tend to have IG that belongs to w/c subclasses?

83.A (+)ANA w/ pattern of anti-centromere ab is most frequently seen in px with:

66. Cells from a px w/ hairy cell leukemia have immunologic and functional features of:

6. In skin test, a wheal & flare development is:

11.20nm spheres & filamentous structures of HBV

88. Substances that are antigenic only when coupled to a protein carrier are:

30. IMMUNOlogic mtd utilized in the FLOW cytometer?

98. Tumor-asso transplantation ag are not found in:

49. A suspected anthrax lesion was submitted to the lab for preparation and testing. The test of choice

55. Which of the ff is an important marker for the presence of immature B cells in px with ALL?

21. The visible serological rxn between soluble ag & its specific ab is:

71.A px w/ B cell deficIeNCy will most likely exhibit:

27. IL-4 can stimulate B cells to produce IgE, a major contributor to:

80. The Mantoux test for M. tuberculosis is based on

81. The profile that matches the typical test profile for chronic active hepatitis due to hepatitis B virus is:

95. PCR is extremely sensitive, but testing is often complicated by:

8. Immunoglobulin idiotypic diversity is explained by

3. Ab class & ab subclass are determined by major physiochemical differences & antigenic variation found primarily in the

97. Polyclonal B cell activation:

82.RheuMatoid factor is most often of w/c of the ff classes:

23.w/c lab technique most frequently use to diagnos & follow the course of therapy of px w/ 2ndary syphilis?

75. Which of the ff is most likely to activate the alternative patHway of complement activation?

48. The assembly of the complement "membrane attack unit" is initiated with the binding of:

76. The IIF staining pattern on ethanol-fixed leukocytes slides shows a perinuclear or nuclear staining pattern. This pattern is typically due to:

91. The procedure for compatibility testing in organ transplant medicine is very similar for the donor & the recipient. One additional procedure that the recipient must undergo that is not relevant to the donor testing is:

72. W/c of the ff is released during T cell activation?

35. The APR that has the fastest response time & can rise 100X is?

99. For the diagnosis of late latent or tertiary syphilis, the most appropriate assay is:

1.Floculation test for syphilis detect the presence of:

4. A serological test for syphilis that depends upon the detection of cardiolipin-lecithin-cholesterol ag is:

58. A haptenic determinant will react with:

89. A substrate is first exposed to a px serum, then after washing, anti-human immunoglobulin labeled with a fluorochrome is added. The procedure described is:

64.W/c of the ff is an organ specific autoimmune dse

33.The enzyme cntrl tube in ASO hemolytic assay exhibits no cell lysis.What is the most likely explanation

56. Initiation of the activation mechanism of the alternative complement pathway differs from that of the classical pathway in that:

92. In hybridoma technology, the desirable fused cell

45. The primary advantage of the labeled immunoassays compared to unlabeled immunoassays is:

77.The result of an ANA test was a titer of 1:320 w/ a peripheral pattern.W/c of the ff sets of results best correlate w/ these results?

39. the test results above,it can be concluded that px #3 has:

14.Blood is drawn from a px for a serological test for a viral dse shortly after the time of onset & again 4wks later. The results of the test are considered diagnostic if:

63. The technologist observes apparent homogenous staining of nucleus of interphase cells while performing an IFA-ANA, as well as staining of the chromosomes in mitotic cells. This results is:

59. Components of the complement system most likely to coat a cell are:

61.W/c of the ff complement components is a strong chemotactic factor as well as a strong anaphylatoxin?

15. The best mtd to detect infections due to rubella, Epstein-Barr & HIV is:

57. Soluble immune complexes r formed under the condition of:

94. Antibody idiotype is dictated by the:

17. T lymphocytes that possess the CD8 surface marker mediate which of the ff T cell functions?

7. Rheumatoid factors are immunoglobulins with specificity for allotypic determinants located on the:

37. The kEy Structural difference that distinguishes immunoglobulin subclasses is the:

65. A single, reliable screening test for detecting neonatal infection in the absence of clinical signs is:

84. Which of the ff activities is associated with C3b?

9.the ff pattern of aggln was observed in ab titration: This set of reactions most likely resulted from:

67. Cytokines involved in innate immune regulation include all but:

10. Bone marrow transplant donors & their recipients must be matched for which antigen system(s)?

43. Sera to be tested for IFA-ANA 6days after drawing is best stored at:

85. A DPT vaccination is an example of:

38. W/c of the ff is most useful in establishing a diagnosis in convalescence phase of a viral infection?

36. procedure has been routinely used for detection of HBsAg because of its high level of sensitivity:

54. Anti-glomerular basement membrane antibody is most often associated with this condition:

16. Immunodeficiency w/ thrombocytopenia & eczema is often referred to as:

29.ratio of kappa to lambda light chain producing cells in normal individuals

44. The most commonly used serological indicator of recent streptococcal infection is the antibody to:

90. Methods of target amPlification in molecular testing include all but:

12. Antihistamines like Benadryl:

20.Ab directed at native DNA are most frequently asso w/ w/c pattern of fluorescence in the IFA-ANA test?

32. Incompatibility by which of the ff procedures is an absolute contraindication to allotransplantation?

79. Hereditary angioedema is characterized by: