1.Floculation test for syphilis detect the presence of:

2. MHC class III genes code for

3. Ab class & ab subclass are determined by major physiochemical differences & antigenic variation found primarily in the

4. A serological test for syphilis that depends upon the detection of cardiolipin-lecithin-cholesterol ag is:

5. A heterophile antigen is best described as?

6. In skin test, a wheal & flare development is:

7. Rheumatoid factors are immunoglobulins with specificity for allotypic determinants located on the:

8. Immunoglobulin idiotypic diversity is explained by

9.the ff pattern of aggln was observed in ab titration: This set of reactions most likely resulted from:

10. Bone marrow transplant donors & their recipients must be matched for which antigen system(s)?

11.20nm spheres & filamentous structures of HBV

12. Antihistamines like Benadryl:

13. Multiplex bead assays for the detection of cytokines are efficient quantifiers of numerous cytokines at one time. One complication of such testing is:

14.Blood is drawn from a px for a serological test for a viral dse shortly after the time of onset & again 4wks later. The results of the test are considered diagnostic if:

15. The best mtd to detect infections due to rubella, Epstein-Barr & HIV is:

16. Immunodeficiency w/ thrombocytopenia & eczema is often referred to as:

17. T lymphocytes that possess the CD8 surface marker mediate which of the ff T cell functions?

18. MHC class I includes which peptides / proteins?

19.The ag marker most closely asso w/ transmissibility of HBV infection is:

20.Ab directed at native DNA are most frequently asso w/ w/c pattern of fluorescence in the IFA-ANA test?

21. The visible serological rxn between soluble ag & its specific ab is:

22. The hyperviscosity syndrome is most likely to be seen in monoclonal dse of which of the ff IG classes?

23.w/c lab technique most frequently use to diagnos & follow the course of therapy of px w/ 2ndary syphilis?

25. The ff cold agglutinin titer results are observed:

26. On a follow-up visit to her dr, a young woman was given the results of her FTA-ABS test. She had been symptomatic for a couple months b4 this visit, w/ fever swollen cervical lymph nodes, fatigue,& rash affecting the palms of her hands & the soles of her feet,but she was now feeling better.Earlier test strategies that u would expect the dr. to have requested include all of the ff EXCEPT:

27. IL-4 can stimulate B cells to produce IgE, a major contributor to:

28. A px abnormal lymphocytes are CD2(+)ag, lack C3 receptors,& are surface IG(-) This can be classified as a disorder of:

29.ratio of kappa to lambda light chain producing cells in normal individuals

30. IMMUNOlogic mtd utilized in the FLOW cytometer?

31. In indirect ELISA mtd designed to detect ab to the rubella virus in px serum the conjugate used should be:

32. Incompatibility by which of the ff procedures is an absolute contraindication to allotransplantation?

33.The enzyme cntrl tube in ASO hemolytic assay exhibits no cell lysis.What is the most likely explanation

34. The strength of a visible reaction is known as:

35. The APR that has the fastest response time & can rise 100X is?

36. procedure has been routinely used for detection of HBsAg because of its high level of sensitivity:

37. The kEy Structural difference that distinguishes immunoglobulin subclasses is the:

38. W/c of the ff is most useful in establishing a diagnosis in convalescence phase of a viral infection?

39. the test results above,it can be concluded that px #3 has:

40. The J-chain is asso w/ w/c of the ff IG?

41. Chronic transplant rejection is a cell mediated & humoral immune response that involves all the ff EXCEPT:

42. serological test that can be modified to selectively detect only specific IgM ab in untreated serum is:

43. Sera to be tested for IFA-ANA 6days after drawing is best stored at:

44. The most commonly used serological indicator of recent streptococcal infection is the antibody to:

45. The primary advantage of the labeled immunoassays compared to unlabeled immunoassays is:

46. SLE px often have which of the ff test results?

47.Mantoux skin test to identify infxn w/ M. tuberculosis

48. The assembly of the complement "membrane attack unit" is initiated with the binding of:

49. A suspected anthrax lesion was submitted to the lab for preparation and testing. The test of choice

50. C3b and Fc receptors are present on:

51. Hep B, a dse arising from a DNA virus, is diagnosed in its acute phase via serology for HBsAg, HBeAg, IgM alpha-HBC and total alpha-HBc. Once a px reaches chronic HBV infxn, effectiveness of therapy may be evaluated using:

52. The area of the IG molecule referred to as the hinge region is located between which domains?

53. Biological false(+)VDRL rxn are frequently encountered in px with:

54. Anti-glomerular basement membrane antibody is most often associated with this condition:

55. Which of the ff is an important marker for the presence of immature B cells in px with ALL?

56. Initiation of the activation mechanism of the alternative complement pathway differs from that of the classical pathway in that:

57. Soluble immune complexes r formed under the condition of:

58. A haptenic determinant will react with:

59. Components of the complement system most likely to coat a cell are:

60. A px returns from a camping trip, where he vacationed for several days in a tick-endemic environment.1month after his return home, he visited his health care provider w/ complaints of fatigue, numbness & history of rash surrounding an insect bite that occurred immediately on his return home from vacation. Suspecting Lyme disease, his clinician ordered an ELISA to test for Lyme ab, results of w/c were equivocal on 2 diff tests. His health care provider then ordered follow-up testing with:

61.W/c of the ff complement components is a strong chemotactic factor as well as a strong anaphylatoxin?

62. W/c of the ff is the most common humoral immune deficiency dse?

63. The technologist observes apparent homogenous staining of nucleus of interphase cells while performing an IFA-ANA, as well as staining of the chromosomes in mitotic cells. This results is:

64.W/c of the ff is an organ specific autoimmune dse

65. A single, reliable screening test for detecting neonatal infection in the absence of clinical signs is:

66. Cells from a px w/ hairy cell leukemia have immunologic and functional features of:

67. Cytokines involved in innate immune regulation include all but:

68. Macrophages are characterized by:

69.HLA-B8 ag has been asso w/ w/c of ff pairs of dse

70.W/c test is used to evaluate cellular immune system in a px?

71.A px w/ B cell deficIeNCy will most likely exhibit:

72. W/c of the ff is released during T cell activation?

73.Anti-phospholipid ab asso w/ autoimune disorders tend to have IG that belongs to w/c subclasses?

74. A 16yo boy w/ infectious mononucleosis has a cold agglutinin titer of 1:2000. An important consideration of this antibody's clinical relevance is the:

75. Which of the ff is most likely to activate the alternative patHway of complement activation?

76. The IIF staining pattern on ethanol-fixed leukocytes slides shows a perinuclear or nuclear staining pattern. This pattern is typically due to:

77.The result of an ANA test was a titer of 1:320 w/ a peripheral pattern.W/c of the ff sets of results best correlate w/ these results?

78.W/c of the ff has been asso w/ px who have homozygous C3 deficiency?

79. Hereditary angioedema is characterized by:

80. The Mantoux test for M. tuberculosis is based on

81. The profile that matches the typical test profile for chronic active hepatitis due to hepatitis B virus is:

82.RheuMatoid factor is most often of w/c of the ff classes:

83.A (+)ANA w/ pattern of anti-centromere ab is most frequently seen in px with:

84. Which of the ff activities is associated with C3b?

85. A DPT vaccination is an example of:

86.W/c of the ff IG is the most efficient at aggln?

87. Antibody allotype is determined by the:

88. Substances that are antigenic only when coupled to a protein carrier are:

89. A substrate is first exposed to a px serum, then after washing, anti-human immunoglobulin labeled with a fluorochrome is added. The procedure described is:

90. Methods of target amPlification in molecular testing include all but:

91. The procedure for compatibility testing in organ transplant medicine is very similar for the donor & the recipient. One additional procedure that the recipient must undergo that is not relevant to the donor testing is:

92. In hybridoma technology, the desirable fused cell

93. Immunoassays are based on the principle of:

94. Antibody idiotype is dictated by the:

95. PCR is extremely sensitive, but testing is often complicated by:

96.W/c of the ff is the larger residual split portion of C3?

97. Polyclonal B cell activation:

98. Tumor-asso transplantation ag are not found in:

99. For the diagnosis of late latent or tertiary syphilis, the most appropriate assay is:

100. What kind of ag-ab rxn would be expected if soluble antigen is added to homologous antibody?