Bloodbank 1

96問 • 1年前

問題一覧

1.blood component used in the tment of hemophilia A

Factor 8

2. 6units of RBC are issued to the OR at 9am in a cooler, validated to maintain a temp of 1-10.C for 2hrs. 40mins later, the cooler containing the units of blood is returned to the BB as surgery was cancelled. What should be done with these units?

inspect units & establish that appropriate temp has been maintained

3. A patient's red cells type as follows:

R0R0

4.Many enhancement media used in BB to promote hemaggln in the presence of IgG ab by reducing w/c of the ff?

zeta potential

5. Which of the following is the immunodominant sugar responsible for the A antigen?

N-Acetylgalactosamine

6. A spx of cord blood is submitted to the transfusion service for routine testing. The ff results are obtained: It is known that the father is group B, with the genotype of cde/cde. Of the following 4 antibodies, which 1 is the most likely cause of the positive direct antiglobulin test?

anti-c

7. W/c of the ff ag is most likely involved in HDFN?

Kell

8. Which of the following must be verified in the transfusion service prior to the issue of blood products

expiration date &, if applicable, expiration time of the blood product

9. Cryoprecipitated AHF, if maintained in the frozen state at -18.C or below, has a shelf-life of:

12months

10. Consider the ff ABO typing results:

cold autoantibody

11.Isoimmunization to plt ag HPA-1a & placental transfer of maternal ab would be expected to coz newborn

thrombocytopenia

12. A px serum reacted weakly positive(1+w) w/16 of 16 grpO panel cells at the AHG test phase. The autocontrol(-).Test w/ ficin-treated panel cells demonstrated no reactivity at the AHG phase. W/c ab is most likely responsible for these results?

anti-Ch

13. Transfusion of which of the following is needed to help correct hypofibrinogenemia due to DIC?

Cryoprecipitate AHF

14.W/c ff ab is neutralizble by pooled human plasma?

anti-Ch

15.W/c ff practices at the time of blood collection helps minimize bacteria contamination of plt products?

diversion pouch

16.50yo px w/ ALL has symptoms of dyspnea,visual abnormalities & headache.blast count is >100,000/uL. What type of apheresis is indicated to treat this px?

cytapheresis to remove immature lymphocytes

17.W/c of the ff blood grp ag is the most immunogenic, or has the greatest ability to initiate ab prodn in an individual who lacks the ag?

18. A 26yo F is admitted with anemia of undetermine origin. Blood samples are received w/ a xm request for 1 unit of RBC. The px is grpA, Rh(-) & no history of transfusion or pregnancy. The ff results were obtained in pretransfusion testing: The next step to continue this investigation would be:

perform a warm autoadsorption

19. Prior to initiating a blood transfusion, the transfusionist and another qualified individual must:

match the blood component to the recipient using 2 independent identifiers

20. Which of the ff is the preferred spx for the initial compatibility testing in exchange transfusion therapy?

maternal serum

21. Anti-Fy3 will fail to react with which of ff enzyme treated red cells?

Fy(a-b-)

22. The preferred replacement fluid to maintain normal oncotic pressure and intravascular fluid levels for patients who has therapeutic plasma exchange for TTP:

plasma

23. Which of the following disease states is treated with therapeutic plasma exchange?

myasthenia gravis

24. According to AABB standards, w/c of the ff donors may be accepted as a blood donor?

spontaneous abortion at 2months of pregnancy, 3months previously

25. What is the primary reason that infectious agents can be transmitted following blood transfusion?

donor in the window period of early infection

26. Which of the ff phenotypes will react with anti-f?

27. A unit of FFP was inadvertently thawed & then immediately fridge at 4.C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement for:

Factor IX

28. LISS acts as an enhancement medium & facilitates antibody uptake by:

reducing zeta potential

29. According AABB Standards, Platelets prepared from Whole Blood shall have at least:

5.5 X 1010 plts per unit in at least 90% of the units tested

30. Anti-K is identified in a patient's serum. If random xm are performed on 10donor units, approx how many would be expected to be compatible?

31. During storage,the conc of 2,3-DPG ↓ in a unit of:

RBC

32. According to AABB Stds, at least 90% of all Apheresis Platelets units tested shall contain a minimum of how many platelets?

3.0 X 1011

33. Which of the ff rgts is used to facilitate hemaggln ff the sensitization of red cells with an IgG alloab?

anti-human globulin serum

34. Rh immune globulin administration would not be indicated in an Rh-negative woman who has a(n):

anti-D titer of 1:4,096

35. The following results were obtained:

Rh HDFN, infant has a False(-) Rh typing

36. Refer to the following information: What’s the best interpretation for lab data given above?

mom has a larger than (N) FMH

37. Which of the following must be included on the label of a unit of Red Blood Cells Leukocytes Reduced?

unique collection facility identifier

38. In order to be a plateletapheresis donor, the platelet count must be at least:

150,000/uL

39.Plastic bag overwraps are recommended when thawing units of FFP in 37.C water baths because they prevent:

the entry ports from becoming contaminated with water

40. The transport temperature for Apheresis Platelets:

20-24C

41. Which of the following must be performed on a patient before and after receiving a blood transfusion?

BP, pulse, respiration rate & temp

42. An acid elution stain was made using a 1hr post-delivery maternal blood sample. Out of 2,000 cells that were counted, 30 of them appeared to contain fetal hgb. It is the policy of the medical center to add 1vial of RhIg to the calculated dose when the estimated vol of hemorrhage exceeds 20mL of WB. Calculate the no. of vials of RhIg that would be indicated under these circumstances

43. When plts are stored on a rotator set on an open bench top, the ambient air temp must be recorded:

every 4hrs

44. An important determinant of platelet viability during storage is:

plasma pH

45. Which of the ff practices has been useful in reducing the incidence of TRALI?

use of FFP from male donors

46.Therapeutic plasmapheresis is performed in order

treat px w/ plasma ab

47.most important step in the safe admin of blood is

accurately identify the donor unit & recipient

48. Which of the following is proper procedure for preparation of Platelets from Whole Blood?

light spin followed by a hard spin

49. Which of the following is the correct interpretation of this saliva neutralization testing?

group O secretor

50. To prevent graft vs host disease, RBC prepared for infants who have received intrauterine transfusions should be:

irradiated

51. Upon expiration, a unit of thawed Plasma Frozen Within 24 Hours (PF24) is converted to thawed Plasma. This thawed Plasma can be stored for an additional:

4 days

53. A negative result using solid phase adherence assays will demonstrate indicator red cells as:

a red blood cell pellet in the bottom of the well

54. Polyspecific AHG reagents contain:

anti-IgG & anti-C3d

55. An obstetrical px has had 3 previous pregnancies. Her 1st baby was healthy, the 2nd was jaundiced at birth & required an exchange transfusion, while the 3rd was stillborn. Which of the ff is the most likely cause?

Rh incompatibility

56. Genes of the MHC :

contribute to coordination of cellular & humoral immunity

57. Plasma Frozen w/in 24hrs after phlebotomy (PF24) & thawed for transfusion has an expiration of:

24 hours

58. A Kleihauer-Betke stain of a postpartum blood film revealed 0.3% fetal cells.What’s the estimated vol(mL)of fetomaternal hemorrhage expressed as WB?

59.W/c of the ff BB chemicals produce Kell null cells

DTT

60. HLA antibodies are:

induced by multiple transfusions

61. What method may be used to resolve the patient's ABO serum typing?

cold-autoadsorption

62. Plasma exchange is recommended in the treatment of patients with macroglobulinemia in order to remove:

excess IgM

63. When the red cells of an individual fail to react w/ anti-U, they usually fail to react with:

anti-S

64. QC of Apheresis Granulocytes must demonstrate w/c of the ff granulocyte counts in 75% of units tested?

1.0 X 1010

65.The autoantibody most often implicated in PCH is:

cold-reactive,IgG,anti-P

66. Cold aglutinin dse is asso w/ an ab specificity toward which of the ff?

67. When the main objective of an exchange transfusion is to remove the infant's ab-sensitized RBC & to control hyperbilirubinemia, the blood product of choice is ABO compatible:

RBC suspended in FFP

68. Proteolytic enzyme treatment of red cells usually destroys which antigen?

Fya

69. What % of grpO donors would be compatible w/ a serum sample that contained anti-X & anti-Y if X ag is present on red cells of 5 of 20 donors, & Y ag is present on red cells of 1of10 donors?

70. Criteria determining RhIg eligibility include:

mom has not been previously immunized to the D ag

71. A px in immediate post BM transplant period has a hct of 21%. The red cell product of choice for this px

irradiated

72. A cause for indefinite deferral of blood donation

positive test for Trypanosoma cruzi

73.In a random population, 16%people are Rh(-) (rr). What % of the Rh(+) population is heterozygous for r?

48%

74. In CGD, granulocyte function is impaired. An asso exist between this clinical condition & a depression of w/c of the ff ag?

Kell

75. Based on these rxn, what is the px ABO type?

76. Which of the following blood group antibodies will no longer react with its respective antigens once those antigens are treated with proteolytic enzymes?

anti-Fya

77. W/c viral dse have a ↓ incidence of transfusion-asso infections due to nucleic acid testing (NAT)?

HIV-1, HCV, WNV

79. W/c of the ff would be the best source of Plts for transfusion in case of alloimmune neonatal thrombocytopenia?

mom

80. Which of the following is considered to be a high prevalence antigen?

Vel

81. Antibodies from which of the following blood group systems are notorious for causing delayed HTR?

Kidd

82. In prenatal workup, the ff results were obtained:

wash px RBC & repeat testing

83.4+(+)rxn using gel technolog will appear as RBC:

in a layer at the top of the gel media

84. During the issue of an autologous unit of WB, the supernatant plasma is observed to be dark red. What would be the best course of action?

quarantine the unit for further testing

85. The ff ABO results are noted on a sample from a 90yo male admitted to the ER for possible GI bleeding:

px age

86. During the preparation of Plts from WB, the blood should be:

cooled towards 20-24.C

89.PCH is asso w/ the ab specificity toward w/c of ff?

P ag

⭐️90. Of the ff blood components, w/c on should be used to prevent HLA alloimmunization of the recipient?

Leukocyte Reduced RBC

91. A false(-)DAT can be the result of:

neutralized AHG rgt

92.An intraoperative strategy for px blood management is:

acute normovolemic hemodilution

93. RBC, Leukocytes Reduced must be stored at:

1-6C

94. A sample give the following results: W/c lectin should be used 1st to resolve dis discrepancy?

Dolichos biflorus

95. Most blood grp systems are inherited as:

autosomal codominant

96.Blood typing after a normal labor & delivery showed that the mother is grpA, D(-) & demonstrates anti-D in her serum.Her slightly jaundiced newborn is anemic & types as grpO, D(-) w/ a 4+ DAT. Previous lab work showed that the father was grpO,D(+). From the information given, which test result is questionable?

newborn D type

97. Laboratory studies of maternal & cord blood yield the ff results: If exchange transfusion is necessary, the best choice of blood is:

O,Rh(+),E-

98. In which of the ff is the IAT utilized?

ab detection test

99. The purpose of performing ab titers on serum from an immunized pregnant woman is to:

identify candidates requiring additional fetal red cells

100. What is the approx probability of finding compatible blood among random Rh(+)units for a px who has anti-c & anti-K?(Consider that 20% of Rh(+) donors lack c & 90% lackK)

18%

clinical microscopy

clinical microscopy

clinical chemistry

clinical chemistry

immunology & serology

ユーザ名非公開 · 99問 · 1年前

immunology & serology

hematology

hematology

microbiology

microbiology

molecular biology

molecular biology

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ユーザ名非公開 · 99問 · 1年前

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問題一覧

1.blood component used in the tment of hemophilia A

Factor 8

inspect units & establish that appropriate temp has been maintained

3. A patient's red cells type as follows:

R0R0

4.Many enhancement media used in BB to promote hemaggln in the presence of IgG ab by reducing w/c of the ff?

zeta potential

5. Which of the following is the immunodominant sugar responsible for the A antigen?

N-Acetylgalactosamine

anti-c

7. W/c of the ff ag is most likely involved in HDFN?

Kell

8. Which of the following must be verified in the transfusion service prior to the issue of blood products

expiration date &, if applicable, expiration time of the blood product

9. Cryoprecipitated AHF, if maintained in the frozen state at -18.C or below, has a shelf-life of:

12months

10. Consider the ff ABO typing results:

cold autoantibody

11.Isoimmunization to plt ag HPA-1a & placental transfer of maternal ab would be expected to coz newborn

thrombocytopenia

anti-Ch

13. Transfusion of which of the following is needed to help correct hypofibrinogenemia due to DIC?

Cryoprecipitate AHF

14.W/c ff ab is neutralizble by pooled human plasma?

anti-Ch

15.W/c ff practices at the time of blood collection helps minimize bacteria contamination of plt products?

diversion pouch

16.50yo px w/ ALL has symptoms of dyspnea,visual abnormalities & headache.blast count is >100,000/uL. What type of apheresis is indicated to treat this px?

cytapheresis to remove immature lymphocytes

17.W/c of the ff blood grp ag is the most immunogenic, or has the greatest ability to initiate ab prodn in an individual who lacks the ag?

perform a warm autoadsorption

19. Prior to initiating a blood transfusion, the transfusionist and another qualified individual must:

match the blood component to the recipient using 2 independent identifiers

20. Which of the ff is the preferred spx for the initial compatibility testing in exchange transfusion therapy?

maternal serum

21. Anti-Fy3 will fail to react with which of ff enzyme treated red cells?

Fy(a-b-)

22. The preferred replacement fluid to maintain normal oncotic pressure and intravascular fluid levels for patients who has therapeutic plasma exchange for TTP:

plasma

23. Which of the following disease states is treated with therapeutic plasma exchange?

myasthenia gravis

24. According to AABB standards, w/c of the ff donors may be accepted as a blood donor?

spontaneous abortion at 2months of pregnancy, 3months previously

25. What is the primary reason that infectious agents can be transmitted following blood transfusion?

donor in the window period of early infection

26. Which of the ff phenotypes will react with anti-f?

27. A unit of FFP was inadvertently thawed & then immediately fridge at 4.C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement for:

Factor IX

28. LISS acts as an enhancement medium & facilitates antibody uptake by:

reducing zeta potential

29. According AABB Standards, Platelets prepared from Whole Blood shall have at least:

5.5 X 1010 plts per unit in at least 90% of the units tested

30. Anti-K is identified in a patient's serum. If random xm are performed on 10donor units, approx how many would be expected to be compatible?

31. During storage,the conc of 2,3-DPG ↓ in a unit of:

RBC

32. According to AABB Stds, at least 90% of all Apheresis Platelets units tested shall contain a minimum of how many platelets?

3.0 X 1011

33. Which of the ff rgts is used to facilitate hemaggln ff the sensitization of red cells with an IgG alloab?

anti-human globulin serum

34. Rh immune globulin administration would not be indicated in an Rh-negative woman who has a(n):

anti-D titer of 1:4,096

35. The following results were obtained:

Rh HDFN, infant has a False(-) Rh typing

36. Refer to the following information: What’s the best interpretation for lab data given above?

mom has a larger than (N) FMH

37. Which of the following must be included on the label of a unit of Red Blood Cells Leukocytes Reduced?

unique collection facility identifier

38. In order to be a plateletapheresis donor, the platelet count must be at least:

150,000/uL

39.Plastic bag overwraps are recommended when thawing units of FFP in 37.C water baths because they prevent:

the entry ports from becoming contaminated with water

40. The transport temperature for Apheresis Platelets:

20-24C

41. Which of the following must be performed on a patient before and after receiving a blood transfusion?

BP, pulse, respiration rate & temp

43. When plts are stored on a rotator set on an open bench top, the ambient air temp must be recorded:

every 4hrs

44. An important determinant of platelet viability during storage is:

plasma pH

45. Which of the ff practices has been useful in reducing the incidence of TRALI?

use of FFP from male donors

46.Therapeutic plasmapheresis is performed in order

treat px w/ plasma ab

47.most important step in the safe admin of blood is

accurately identify the donor unit & recipient

48. Which of the following is proper procedure for preparation of Platelets from Whole Blood?

light spin followed by a hard spin

49. Which of the following is the correct interpretation of this saliva neutralization testing?

group O secretor

50. To prevent graft vs host disease, RBC prepared for infants who have received intrauterine transfusions should be:

irradiated

51. Upon expiration, a unit of thawed Plasma Frozen Within 24 Hours (PF24) is converted to thawed Plasma. This thawed Plasma can be stored for an additional:

4 days

53. A negative result using solid phase adherence assays will demonstrate indicator red cells as:

a red blood cell pellet in the bottom of the well

54. Polyspecific AHG reagents contain:

anti-IgG & anti-C3d

Rh incompatibility

56. Genes of the MHC :

contribute to coordination of cellular & humoral immunity

57. Plasma Frozen w/in 24hrs after phlebotomy (PF24) & thawed for transfusion has an expiration of:

24 hours

58. A Kleihauer-Betke stain of a postpartum blood film revealed 0.3% fetal cells.What’s the estimated vol(mL)of fetomaternal hemorrhage expressed as WB?

59.W/c of the ff BB chemicals produce Kell null cells

DTT

60. HLA antibodies are:

induced by multiple transfusions

61. What method may be used to resolve the patient's ABO serum typing?

cold-autoadsorption

62. Plasma exchange is recommended in the treatment of patients with macroglobulinemia in order to remove:

excess IgM

63. When the red cells of an individual fail to react w/ anti-U, they usually fail to react with:

anti-S

64. QC of Apheresis Granulocytes must demonstrate w/c of the ff granulocyte counts in 75% of units tested?

1.0 X 1010

65.The autoantibody most often implicated in PCH is:

cold-reactive,IgG,anti-P

66. Cold aglutinin dse is asso w/ an ab specificity toward which of the ff?

67. When the main objective of an exchange transfusion is to remove the infant's ab-sensitized RBC & to control hyperbilirubinemia, the blood product of choice is ABO compatible:

RBC suspended in FFP

68. Proteolytic enzyme treatment of red cells usually destroys which antigen?

Fya

69. What % of grpO donors would be compatible w/ a serum sample that contained anti-X & anti-Y if X ag is present on red cells of 5 of 20 donors, & Y ag is present on red cells of 1of10 donors?

70. Criteria determining RhIg eligibility include:

mom has not been previously immunized to the D ag

71. A px in immediate post BM transplant period has a hct of 21%. The red cell product of choice for this px

irradiated

72. A cause for indefinite deferral of blood donation

positive test for Trypanosoma cruzi

73.In a random population, 16%people are Rh(-) (rr). What % of the Rh(+) population is heterozygous for r?

48%

74. In CGD, granulocyte function is impaired. An asso exist between this clinical condition & a depression of w/c of the ff ag?

Kell

75. Based on these rxn, what is the px ABO type?

76. Which of the following blood group antibodies will no longer react with its respective antigens once those antigens are treated with proteolytic enzymes?

anti-Fya

77. W/c viral dse have a ↓ incidence of transfusion-asso infections due to nucleic acid testing (NAT)?

HIV-1, HCV, WNV

79. W/c of the ff would be the best source of Plts for transfusion in case of alloimmune neonatal thrombocytopenia?

mom

80. Which of the following is considered to be a high prevalence antigen?

Vel

81. Antibodies from which of the following blood group systems are notorious for causing delayed HTR?

Kidd

82. In prenatal workup, the ff results were obtained:

wash px RBC & repeat testing

83.4+(+)rxn using gel technolog will appear as RBC:

in a layer at the top of the gel media

84. During the issue of an autologous unit of WB, the supernatant plasma is observed to be dark red. What would be the best course of action?

quarantine the unit for further testing

85. The ff ABO results are noted on a sample from a 90yo male admitted to the ER for possible GI bleeding:

px age

86. During the preparation of Plts from WB, the blood should be:

cooled towards 20-24.C

89.PCH is asso w/ the ab specificity toward w/c of ff?

P ag

⭐️90. Of the ff blood components, w/c on should be used to prevent HLA alloimmunization of the recipient?

Leukocyte Reduced RBC

91. A false(-)DAT can be the result of:

neutralized AHG rgt

92.An intraoperative strategy for px blood management is:

acute normovolemic hemodilution

93. RBC, Leukocytes Reduced must be stored at:

1-6C

94. A sample give the following results: W/c lectin should be used 1st to resolve dis discrepancy?

Dolichos biflorus

95. Most blood grp systems are inherited as:

autosomal codominant

newborn D type

97. Laboratory studies of maternal & cord blood yield the ff results: If exchange transfusion is necessary, the best choice of blood is:

O,Rh(+),E-

98. In which of the ff is the IAT utilized?

ab detection test

99. The purpose of performing ab titers on serum from an immunized pregnant woman is to:

identify candidates requiring additional fetal red cells

100. What is the approx probability of finding compatible blood among random Rh(+)units for a px who has anti-c & anti-K?(Consider that 20% of Rh(+) donors lack c & 90% lackK)

18%