part 4

Arda Emre HAN · 76問 · 2年前

通報

問題一覧

All enzymes are divided into:

6 classes

Which of the following is not coenzyme?

pyridoxine

the first class in the enzyme classification is:

oxidoreductases

the scecond class in the enzyme classification is:

transferases

Determine the enzyme with the relative specificity.

hexokinase

Substrates of proteases are:

proteins

the third class in the enzyme classification is:

hydorlases

What is the basis for the classification of enzymes?

type of catalyzing reaction

the fourth class in the enzyme classification is:

lyases

What is the reason of enzymes inactivation at the temperature more than 50°C?

denaturation

Reduced concentration of which substances increases the speed of reaction with participation of proteases?

amino acids

Protein part of complex enzymes is called:

apoenzyme

Which of the following functional groups of enzyme molecule participate in catalytic process? 1) SH- group of cysteine 2) Imidazole group of histidine molecule 3) Hydroxyl group of serine and threonine 4) COOH group of glutamic and aspartic acid

all

What determines the catalytic activity and the specificity of enzyme?

active site

Non-vitamin nature coenzyme is:

monosaccharide

What does not determine the rate of enzymatic reaction?

the molecular mass of enzyme

Non-vitamin nature coenzyme is:

glutathione

Define enzymes having relative specificity.

lipase, pepsin, α-glucosidase

Active site of complex enzymes consists of:

functionally active amino acids

Determine the enzyme (I), which catalyzes the following reaction: Carbamide + H2O→ 2 NH3 + CO2; and its specificity (II):

urease-absolute

Select the correct arrangement of pH optimum for the following enzymes: pepsin (I), trypsin (II), chymotrypsin (III).

I < II = III

Which class does enzyme which catalyzes below reaction correspond to? Glutamic acid + H2O + NAD+ = α-ketoglutaric acid + + NH3 + NADH2

oxidoreductase

How is enzyme different from inorganic catalyst?

It is highly specific

Choose the variant where given value does not correspond to the optimum pH of the enzyme.

catalase (9,5-9,9)

Which one is not the coenzyme of transferases?

FMN

What does the non-competitive inhibitor bind to?

enzyme substrate complex

Define the correspondence between enzyme and disease.

ceruloplasmin - Wilson’s disease

Which amino acid in the enzyme molecule binds with diisopropyl fluorophosphate (DFP) as inhibitor?

serine

Lipase, α-amylase and trypsin belong to the class of:

hydrolases

Which of the following classes of enzymes promotes the intramolecular bond cleavage with the participation of water?

hydrolases

Which value of pH activity of α-amylase of salivary is maximum?

6,8-7,0

Determine the enzyme which catalyzes the reaction: (NH2)2CO+H2O ->2NH3 + CO2 and its specificity.

urease, absolute

Which of the following classes of enzymes catalyzes intramolecular changes?

isomerases

The other name of synthases is:

lyases

How are enzymes that permanently contain metal ions in active site called?

metalloenzymes

Which of the following enzymes catalyzes the following reaction: R – R1 + H OD R – H + R1OH. 2

hydrolase

Which part of enzyme molecule is affected by pH environment

degree of ionization of functional groups

Which class does the enzyme, which catalyzes the following reaction, belong to? CH3COOH+HS-CоА + ATP→CH3CO-CоА + АMP + H4P207

lygases

What is the unit of enzyme activity in the International System of Units ?

katal

Which enzyme is used in the diagnosis of bone diseases?

acid phosphatase

Which class does the enzyme, which catalyzes the following reaction, belong to? Glutamic acid + H2O + NAD+ → α-KGA + NH3+ NADH2

oxidoreductase

Which enzyme is used in the treatment of thrombosis?

urokinase

Select coenzymes which have vitamin nature:

ubiquinone, TPP, NAD+, carnitine

Activity of which enzyme increases in blood in acute pancreatitis?

lipase

Which enzyme drug stops the development of RNA- containing viruses?

ribonuclease

Inhibitor of which enzyme in blood is contrical?

trypsin

Which isoenzyme of lactate dehydrogenase (LDH) catalyzes the following reaction: +2H Pyruvic acid ⎯⎯→ Lactic acid

LDH1, LDH2, LDH3, LDH4, LDH5

Select activator (I) and inactivator (II) of amylase enzyme. I II

Cl Cu2+

How are called enzymes which have ion metals as the regular part of active site?

true metalloenzymes

Define enzymes having absolute specificity.

arginase, urease

Determine the compliance for moniiodacetamid (I) inhibitor type and functional group (II) related with it.

irreversible(I) sulfhydryl(II)

What does pH in the enzyme molecule act on?

ionization degree of functional groups

Which substance is an inhibitor of acetylcholinesterase and why?

diisopropyl fluorophosphate, it binds to the amino acid serine in the active site

Select the correct arrangement of the optimum pH for the following enzymes: α-amylase (I), pepsin (II), catalase (III).

II <III <I

Activity of which isoenzyme of lactate dehydrogenase increases in blood in myocardial infarction (I) and Botkin's disease (II)?

LDH-1 LDH-5

Determine the reason of the change of cholinesterase activity under optimal conditions change pH- 5,0 (I), t=50 °C (II):

change in the conformation of the enzyme molecule

I. R - CH-COOH "R - CH2-NH2 +CO2 | / NH2 II. CO (NH2)2 +H2O" CO2 + 2NH3 Choose classes of enzymes catalyzing reaction I and II.

lyase hidrolase

Find the correlation between the enzyme and the disease in the diagnosis of which it is used: I. Acid phosphatase II. α-Amylase III. Alkaline phosphatase IV. LDH 1. myocardial infraction 2. acute pancreatitis 3. tumor prostates 4. bone tumors

3 2 4 1

Non-protein part of complex enzymes is called ?

coenzyme

What are the functional groups in the active site of the enzyme involved in the process of catalysis? 1. Indol group of tryptophan 2. Imidazole group of histidine 3. Hydroxyl group of serine and threonines 4. Guanidinium group of arginine

all

Enzymes are classified into ?

Which enzymes have flavin coenzymes? 1. Succinate dehydrogenase 2. Dihydrolipoyl dehydrogenase 3. Arginase 4. Xanthine oxidase 5. Transketolase

1, 2, 4

Which site of enzyme provides conversion of substrate?

catalytic site

Which class does enzyme catalyzing below reaction belong to? Acetic acid + HS-CoA + ATP → Acetyl-CoA + ADP + H3PO4

ligase

What is not observed under physiological conditions?

retro inhibition

Reason of enzymes inactivation at the temperature more than 50°C is:

denaruration

What is the optimal temperature for an enzyme action?

37-40°C

Non-protein part of complex enzyme is called:

Coenzyme

Select the correct arrangement of pH optimum for the following enzymes: pepsin (I), α-amylase (II), ximotripsin (III).

I < II < III

Synthesis of which enzymes in body decreases with deficit of vitamin PP ?

NAD, NADP

Which amino acid in the enzyme molecule binds with diisopropyl fluorophosphate (DFP) as inhibitor?

serine

Which value of pH activity of pepsin is maximum?

1,5-2,5

What is appointed in acute pancreatitis to prevent pancreatic autolysis?

inhibitors of proteolytic enzymes

Which enzyme activity decreases in human body with iron deficiency?

catalase

397.

urease, the absolute

What is the unit of enzyme activity in the International System of Units?

katal

Which enzyme activity in human body decreases with copper deficiency?

cytochrome oxidase

What do you need to enter to the patient admitted to the hospital in serious condition as a result of cyanide poisoning?

cytochrome oxidase

Which enzyme is used in the diagnosis of liver diseases?

alkaline phosphatase

Which functional group of aspartic acid may include in the active center of enzyme?

β-carboxyl group

Which enzyme drug stops the development of RNA- containing viruses?

ribonuclease

Allosteric site is:

part of enzyme which promotes attaching effectors

401

pyruvate carboxylase-FAD-pyruvic acid

402

3 2 4 1

Immobilized enzymes are:

artificially formed hydrophobic enzyme complexes with polymers

Which of the following belong to the iron and sulfur- containing flavoproteins?

xanthine oxidase, aldehyde oxidase, succinate dehydrogenase

Which enzyme value in blood is high in patient with myocardial infaction in the first two days?

aspartate aminotransferase

Which group in the active site of enzyme has nucleophilic properties?

hydroxyl group of serine

Which factors determine the speed of the enzyme reaction?

substrate concentration

Which group in the active site of enzyme has nucleophilic properties?

thiol group of cysteine

405

e a d b c

406

c d b a

The curve reflects the dependence of the rate of enzymatic reaction from:

temperature

407

2,3,5. 1,4

Which enzyme has an absolute specificity?

urease

Which enzyme class does catalase belong to?

oxidoreductases

Which enzyme has absolute stereochemical specificity?

fumarate hydratase

Activity of which enzyme increases in blood serum in liver disease?

alanine aminotransferase

For which organ does the LDH1 have a diagnostic value?

heart muscle

100

Determine enzyme X and its prosthetic group: X R H 2 + H 2 O 2 ⎯⎯ → R + 2 H 2 O

peroxidase - precursors of heme

Histo100-200

Histo100-200

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histoloji 200-300

histoloji 200-300

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mikro biyoloji tüm pdfler

mikro biyoloji tüm pdfler

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part 2

part 2

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part 3

part 3

47問 • 2年前

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part 1

part 1

129問 • 2年前

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İctimai Sağlamlık 100soru

İctimai Sağlamlık 100soru

50問 • 2年前

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fizyoloji

fizyoloji

10問 • 2年前

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

gıdalanma final ilk 30

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biyokimya 170-207

biyokimya 170-207

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Patfiz 16-64

Patfiz 16-64

48問 • 2年前

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1-20

1-20

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20-40

20-40

20問 • 2年前

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Epi 91-123

Epi 91-123

33問 • 2年前

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97-112

97-112

16問 • 2年前

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44-86

44-86

39問 • 2年前

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87-130

87-130

43問 • 2年前

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biyokimya 170

biyokimya 170

163問 • 2年前

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mikrop 11-15

mikrop 11-15

17問 • 2年前

gas gagrene

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gas gagrene

5問 • 2年前

tekamul genetikası

tekamul genetikası

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biyofiz 125

biyofiz 125

115問 • 1年前

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50-100

50-100

51問 • 1年前

Arda Emre HAN · 201問 · 1年前

sinav

sinav

201問 • 1年前

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Patfiz kesin çıkacak

Patfiz kesin çıkacak

35問 • 1年前

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patfiz

patfiz

95問 • 1年前

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1-12

1-12

12問 • 1年前

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patanat

patanat

30問 • 1年前

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Patanat son 60

Patanat son 60

38問 • 1年前

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1-42

1-42

37問 • 1年前

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umumi cerrahi

umumi cerrahi

70問 • 1年前

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derma 60-90

derma 60-90

30問 • 1年前

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derma 90-120

derma 90-120

30問 • 1年前

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Radyoloji 1-60

Radyoloji 1-60

60問 • 1年前

radyo ilk 10

radyo ilk 10

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111patfiz50

111patfiz50

48問 • 1年前

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patfiz 400-460

patfiz 400-460

61問 • 1年前

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patfiz

patfiz

10問 • 1年前

genel cerrah ets 1-50

genel cerrah ets 1-50

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genel cerrahi

genel cerrahi

100問 • 1年前

deri 50-100

deri 50-100

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son

son

100問 • 1年前

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emre

emre

40問 • 1年前