問題一覧
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Cells of connective tissue proper
Filroblasts - fibrocytes/ histiocytes-macrophages/ mast cells/ myofibroblasts/ melanocytes/ leukocytes/ plasma cells/ pericytes/ fat cells
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Extracellular matrix ground substance
Glycosaminoglycans glycoproteins proteoglycans
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ECM fibers
Colagen reticular elastic
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What are fibroblasts
Most common cell type in connective tissue
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Fibroblasts synthesize fibers
Colagen reticular elastic
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Fibroblasts synthesize ECM
Glycosaminoglycans glycoproteins
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Fibroblasts are
Young and active
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Fibrocytes are
Old - rest
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Fibrocytes characteristics
Smaller than the active fibroblasts/ spindle shape/ fewer processes/ darker/ elongated nucleus/ acidophilic cytoplasm/ small amount of RER
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Mast cells are
Round and oval
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Mast cells have
Basophilic granules in cytoplasm
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Mast cells secrete
Heparin/ histamine/ ECF-A/ NCF-A/ leukotrienes/ prostaglandin/ thromboxane/ platelet - activating factor
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Heparin is
Anticoagulent
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Histamine
Increases capillary permeability
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ECF -A
Eosinophil chemotactic factor
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NCF-A
Neutrophil chemotactic factor
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Histiocytes ( macrophages ) characteristics
Irregular shape/ nucleus oval eccentric kidney shape/ granular lysosomes/ pseudopodia
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Functions of macrophages ( histiocytes)
Ingestion by phagocytosis/ participate in the breakdown of aged cells including erythrocytes
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Ingestion by phagocytosis
Particulate matter such as dust/ microorganisms bacteria viruses fungi parasites
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Plasma cells
Derive from B lymphocytes/ eccentric nucleus/ dark staining cytoplasm/ lots of RER/ don't leave the connective tissue/ produce antibodies
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Pericytes
Are associated with small blood vessels/ as contractile cells/ probably as pluripotential cells
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Leukocytes
Lymphocytes granulocytes monocytes
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Lymphocytes
B lymphocytes T lymphocytes natural killers ( NK )
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Granulocytes
Neutrophils eosinophils basophils
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Monocytes
Monocytes = macrophages = histiocytes
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Myofibroblasts
Part fibroblastic part muscle - like cells/ having a contractile apparatus similar to the smooth muscle cells/ injury repair after wounding
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Melanocytes
Pigment cells found in the connective tissues the skin and the eye/ melanin produced by these cells is known to absorb ultraviolet light
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Adipose (fat) cells
Mesenchymal cell → lipoblast → white cell and brown cell
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White fat cell
One big fat droplet
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Brown fat cell
Many small fat droplets
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Functions of connective tissue proper
Stroma - support/ protection/ transport/ defense/ storage