haad 4 sterilization

100問 • 2年前

問題一覧

Preparation got contaminated with bacterial endotoxin, how to sterilize?

Filtration

Purified water having bacteria of gram tve and gram -ve, this water is used for manufacturing of the product, which method is used for the sterilization.

Filtration

SWFI that was contaminated with organisme WHICH method is suitable for sterilitici?

Filtration

Some new Formulation needs to be sterilized that is sensitive to heat and is soluble (or gets affected by moisture) what method is best

Filteration

Some new Formulation needs to be sterilized that is sensitive to heat and is soluble (or gets affected by moisture) what method is best

depyroenation

sterile material that is chemically reactive and they mentioned something about heat and that it had large particles?

Filtration

Patch is to be sterilized and it is unstable above 90° and highly reactive. What is the sterilization procedure

Ethylene gas 37-63

Patch is to be sterilized and it is unstable above 90° and highly reactive. What is the sterilization procedure

Chemicals

Iv medication have bacterial growth what best

Filteration

A preparation is entering with gram positive bacteria, it should endotoxic, thus;

depyrogenation if no filteration

Where to prepare cototoxic medicine?

Vertical laminar flow hood

A sterile preparation was prepared in a septic area, what are the precautions that should be taken?

All of the above

Which measure is not appropriate when cleaning a vertical laminar flow hood?

Cleaning the work surface, front to back, right to left

What is NOT the appropriate measure when cleaning a vertical laminar flow hood?

Food and beverage can be stored in ante area and not in the buffer room

Drug cannot be used in MDS:

Letrozole

Which of the following medication can be put together in the same ward?

Furosemide and warfarin

Which medicine can be stored in same compartment?

Warfarin & (ACEls or BB can't remember exactly)

The medicine which can't be manipulated by bare hands as that cause skin irritation

Chlorpromazine

Cytotoxic drug, what's the least thing to be concerned about?

Contaminated bench

Precaution while handling Methotrexate tablet

Use Hand glove

Pharmacy has a new system called Monitor Dosage System. What drug should is appropriate to include in this?

Candesartan

Patient is supposed to take clonazepam, but given carbamazepine, he is under care but no side effects, which category of error is this?

Category D

Patient took one dose of a drug. Bo harm but requires monitoring, which error

Category D

patient supposes to take some medicine but took the other medicine, which cause no harm. What type of error is this:

Pt. was admitted to emergency because of side effects to wrong med. a. Which category of error:

An error occurred but the error didn't reach the patient. This error can be categorized as.

Category B

Which of the following strategies can reduce chemotherapeutic medications errors?

Pharmacist who verify chemo order should calculate dose

patient brought a drug back to pharmacy because it was not effective. After inspection it was found to be expired. What is the least to be done, if any, to ensure this won't happen again?

Nothing to be done its human (manual) error can't be prevented

which of the following is not a way to reduce medication misuse?

Advocating use of unapproved abbreviations

In OPD pharmacy pharmacist dispensed a medicines from bulk stock which was received in store yesterday after some time patient returned the same medicines and complained it is expired medicines. Omission of which appropriate steps would be leaded to this error?

All medicines Expiry should be checked regularly and while receiving and dispensing of medicines

Which of the following represent medication error F

Pharmacist dispense losartan instead of another drug and cause dizziness and hospitalized

Which of the following represent medication error F?

Patient take bisoprolol 5 mg instead of Bisacodyl 5mg, and admitted to the hospital because he experienced dizziness

A pediatric patient who was recovering from brain tumor surgery is given 650 mg dose of Methotrexate into the brain. what kind of error is this?

Wrong Dose

Which one of the following is considered a dangerous abbreviation?

IU for international unit

A prescription with Amoxicillin 5ml OD, the best way to write the directions ?

5 ml 1 teaspoonful 1 time daily

patient come with prescription of ramipril 100 mg. His history showed that he is taking ramipril 10 mg. you have been trying to call physician for 1 hour, but you can't reach him, and the patient is getting anxious. What is the most appropriate action?

Contact the clinic to call the prescriber

prescription error, you are calling the GP but he is not answering what will you do

call the clinic of the Gp and ask them to contact the Gp

What is the best way to write the dose for Digoxin 0.25mg? or Best way of prescribing Digoxin 0.25 mg to avoid error ?

250 mcg

Pharmacy has a new system, after 2 days of it, the pharmacist discovered he made mistak because he doesn't know about the system what to do?

Ask colleague to teach him

Biweekly means: Biweekly Rx for monoclonal antibodies, what to do?

Once every 2 weeks (every other week)

A diabetic pt with HTN and dyslipidemia was ordered to take aspirin 81 and bisoprolol 5 mg and lisinopril 20 and atorvastatin 40 and metformin 1g what is the medication error the doctor made?

BB MASK THE HYPOGLYCEMIC EFFECT

A physician prescribed a cream for 1-month old baby starting with CLOBETA... REMAINING CANT READ PROPERLY. The strength of the cream is mentioned as 0.05%, which is these can be consider regarding the prescription

The prescription is legally invalid

Which of the following circumstances would not require the pharmacist to complete a “medication error “ reporting form ; should they become aware of the incident

non-medical prescriber prescribing azathioprine without first completing TPMT test

What is not a potential concern for recording a Medication error?

Patient does not take levothyroxine at home

The doctor wants to change anticoagulant for discharge patient from IV to NOAC which of the following patients have the best criteria to take? Patient taking multiple medicines including atorvastatin rosuvastatin clopidogrel aspirin

Clopidogrel, aspirin and cholecalciferol

A 61-year-old woman with deep vein thrombosis is on heparin 1200 units/ hour. The nurse asks for heparin dosing recommendation after receiving the hematology test this morning Test Result Normal Values APTT 240. 30-40 sec INR 1.1 0.8-1 .2 Prothrombin time 12 10-13 sec What is the best recommendation based on hospital heparin protocol?

Hold the infusion for 60 minutes, then resume with 1000 units/hour.

following parenteral anticoagulants require routine monitoring of coagulation lab parameters?

UFH intravenously

Which of the following P2Y12 receptor inhibitors exhibit the most variable anti-platelet effects?

Clopidogrel

Stroke or previous TIA transient ischemic attack is a contraindication to the use of which anti-platelet agent?

Prasugrel

The physician is asking the pharmacist about when to discontinue clopidogrel before open- heart surgery. What should the pharmacist suggest?

Discontinue 5 days before surgery.

A 70-year-old man with a history of osteoarthritis is admitted for knee replacement surgery. Postoperative follow up is smooth with no complications. What would be the recommended prophylaxis for venous thromboembolism?

Enoxaparin 40 mg SC every 24 hours

A 78-year-old man recently had acute myocardial infarction and had a drug eluting stent placed. He has a history of hypertension, hypertriglyceridemia, and asthma. What would be the recommendation about anti-platelet therapy in addition to clopidogrel 75 mg daily?

Chewable aspirin 81 mg daily

Patient female with food poisoning and went to hospital with troponin high NSTMI what is the management

aspirin 81 mg + ticagrelor

Which PPI is safe with clopidogrel?

Pantoprazole

The least interaction producing PPI with clopidogril

Pantoprazole

A 55-year-old man with myocardial infarction presents to the clinic with dyspnea interrupting his daily activity. Which of the following medications can cause it?

Ticagrelor

Mother came with child ingested a drug by mistake & having symptoms (nausea & vomiting blood). Test results showed he had metabolic acidosis & leukocytosis. Which of the following is the cause?

aspirin

Aspirin overdose symptom

hyperthermia

Aspirin overdose symptoms are all the following except:

Hypothermia

What is the appropriate mode of taking chewable aspirin tablet

Can be chewed or swallowed.

In patients who require dual antiplatelet therapy, what is the recommended maintenance dose of aspirin when used in combination with ticagrelor?

81 mg

Inpatient with MI taking 5 drugs (prasugrel, bisoprolol, aspirin, & another 4th), upon discharge he found only 4 drugs what is the missing one?

Ramipril

Which NSAID permanently inactivates thromboxin-A2 synthesis in platelets?

Aspirin

A 58-year-old man is admitted in the hospital for DVT treatment. The physician is initiating unfractionated heparin and warfarin therapy. The physician is asking the pharmacist, Which the following about the duration of anticoagulants overlapping in DVT treatment? (What should be the pharmacist recommendation?

Minimum of 5 days of heparin and INR greater than 2.0

Which of the following could lead to decrease PT/INR in a patient on warfarin therapy?

Initiation of phenytoin, carbamazepine, or rifampin

patient is on warfarin for mechanical mitral valve replacement. What should be the INR goal range

2.5-3.5

The patient is taking warfarin and the doctor prescribed fluconazole. The patient came with INR=11 and he’s bleeding. What is the reason of this bleeding?

Fluconazole is an enzyme inhibitor & causes warfarin to accumulate in the blood without metabolizing it.

A patient on warfarin presents with nose bleeding since yesterday. His INR=10, what should be the pharmacist's advice?

Stop warfarin and administer vitamin k till patient’s INR is less than 5

Patient is undergoing Fluconazole treatment for candidiasis. INR is monitored while taking warfarin INR:13, now he is suffering from nose bleeding .What he can do now ? normal inr 1.1 or less if wairf 2-3Patient is undergoing Fluconazole treatment for candidiasis. INR is monitored while taking warfarin INR:13, now he is suffering from nose bleeding .What he can do now ? normal inr 1.1 or less if wairf 2-3

Take vitamin K Stop warfarin and give vit. K till patients inr is less than 5

Which of the following is an important counseling point for patients starting on warfarin?

Keep intake of green leafy vegetables.

Antiarythmic drug that increases warfarin toxicity?

Amiodarone Quinidine

What is the monitoring parameter for warfarin therapy?

INR

Phototoxic drug?

Amiodarone

Patient on amiodarone and other drugs. She started to have palpitations, anxiety, and wight loss. Which drug is associated with her condition?

Hyperthyroidism caused by amiodarone

Patient having high TSH levels. She was taking drugs including amiodarone and ibuprofen. Which drug is associated with her condition?

Amiodarone

A patient is taking Levothyroxine from last 2 year, she is taking amiodarone from last 2 month her Thyroid function test in this time found as following: . T3- very Small Variation (0.1 from normal range). TSH- Very high . T4- Within Normal Limits What will be the cause of this condition?

Amiodarone-induced hypothyroidism

Which of the following antiarrhythmic drugs may cause iodine induced hypothyroidism?

Amiodarone

What is a rare type of adverse drug reaction?

hyperthyroidism from Amiodarone

Which of the following is a rare side effect of amiodarone (less than 1%)):

Peripheral edema

Amiodarone side effect -common

Hypothyroidism

Which of the following is a rare side effect of amiodarone

hyperthyroidism

Which one of the following medications is known to induce pulmonary toxicity?

Amiodarone

A 70-year-old woman is diagnosed with sustained ventricular tachycardia. The resident doctor wants to initiate one of the ClassIll potassium channel blockers. She has a history of Torsades de Pointes arrhythmia and has renal impairment. Which of the following medications is best to initiate?

Amiodarone

At what time should the routine plasma samples for digoxin monitoring be drawn?

6 hours post-dose

A 78-year-old woman with a history of atrial fibrillation and heart failure is on amiodarone, ACEI and B-blocker. She has been taking digoxin to improve symptoms and exercise intolerance. She has a normal renal function. What would be the most appropriate dose of digoxin per day?

62.5 mcg

Which is the anticoagulant preferred during hemodialysis procedure?

Unfractionated heparin

Which one of the following is known side effect of unfractionated heparin?

Hyperkalemia

Glucagon may be used and as an antidote for which of the following?

Metoprolol

A 60-year-old man with history of HF presents with acute attack of gout in his left toe with excruciating pain. He rates his pain as 8/10. Which of the following medications could have contributed (causes) to his acute gout?

Furosemide 40 mg daily

Heparin is chemically bonded to catheters to prevent

Thrombogenicity

A 48-year-old man with myocardial infarction is started on an ACEI. He is started on a low dose and the aim is to titrate to the target dose within four weeks. On routine follow up of labs one week from starting the drug, his serum creatinine is increased by 20% from the baseline. What would be the most appropriate action?

Continue titrating the ACEI

A 65-year-old man with NYHA class-IV heart failure has been started on digoxin to improve his symptoms. Which of the following electrolyte imbalances will predispose him to digoxin toxicity?

Hypercalcemia

A 72-year-old man with a history of hypertension and COPD has EKG finding suggestive of irregular rhythm (see vitals). Blood pressure 135/80 mmHg Heart rate 80/min What is the most appropriate drug to manage his atrial fibrillation?

Verapamil

A 68-year-old woman with a history of type-2 diabetes and dyslipidemia is on atenolol and lisinopril. The doctor has started simvastatin as her estimated 10-year ASCVD risk is 7.5%. What would be the recommended dose for simvastatin?

20 mg

A 52-year-old woman with NYHA Class III Heart Failure was started on lisinopril 40 mg/day and carvedilol 25 mg BID. She is recently complaining of dizziness. Blood pressure 100/70 mmHg Heart rate 70/min What is the best approach for Heart failure and her symptoms?

Decrease lisinopril dose

A 44-year-old man presents to his doctor for blood pressure check. His blood pressure reading is 169/95 mmHg. He has been seeing his doctor several times in the last three months for blood pressure checks and lab tests. Although his lab tests are fine, the doctor recommended him to start blood pressure reducing medicines. Which of the following pharmacotherapy regimens would be most appropriate?

Amlodipine 5 mg with Lisinopril 10 mg in one pill, daily

A 65-year-old man with a history of hypertension, hyperlipidemia, erectile dysfunction, and newly diagnosed diabetes mellitus type II, is on metformin 1000 mg twice daily, lisinopril 10 mg daily, atorvastatin 40 mg once daily, and sildenafil 25 mg as needed. He comes to the pharmacy with a new prescription for metoprolol tartrate 25 mg twice daily. Which one of the following advice should be given?

Metoprolol may mask symptoms of hypoglycemia except for sweating

Prescription containing Frusemide, Bisoprolol, Lisinopril the Disease is?

Patient with hypertension was rushed to the ER due to signs and symptoms of acute kidney injury. These are the drugs she/he were taking: Candesartan, Atorvastatin, Aspirin, Ibuprofen, Bisoprolol, Paracetamol What drugs should be discontinued?

Stop candesartan, aspirin and ibuprofen

100

The result of one patient revealed hyperkalemia and might escalate to arrhythmia. Her current medications are ff… What predisposed her to this complication?

Eplerenone and Ramipril

haad

haad

haad 2

haad 2

haad 3

haad 3

haad 4

haad 4

haad 5

haad 5

haad 6

ユーザ名非公開 · 12回閲覧 · 100問 · 2年前

haad 6

haad 7

haad 7

問題一覧

Preparation got contaminated with bacterial endotoxin, how to sterilize?

Filtration

Purified water having bacteria of gram tve and gram -ve, this water is used for manufacturing of the product, which method is used for the sterilization.

Filtration

SWFI that was contaminated with organisme WHICH method is suitable for sterilitici?

Filtration

Some new Formulation needs to be sterilized that is sensitive to heat and is soluble (or gets affected by moisture) what method is best

Filteration

Some new Formulation needs to be sterilized that is sensitive to heat and is soluble (or gets affected by moisture) what method is best

depyroenation

sterile material that is chemically reactive and they mentioned something about heat and that it had large particles?

Filtration

Patch is to be sterilized and it is unstable above 90° and highly reactive. What is the sterilization procedure

Ethylene gas 37-63

Patch is to be sterilized and it is unstable above 90° and highly reactive. What is the sterilization procedure

Chemicals

Iv medication have bacterial growth what best

Filteration

A preparation is entering with gram positive bacteria, it should endotoxic, thus;

depyrogenation if no filteration

Where to prepare cototoxic medicine?

Vertical laminar flow hood

A sterile preparation was prepared in a septic area, what are the precautions that should be taken?

All of the above

Which measure is not appropriate when cleaning a vertical laminar flow hood?

Cleaning the work surface, front to back, right to left

What is NOT the appropriate measure when cleaning a vertical laminar flow hood?

Food and beverage can be stored in ante area and not in the buffer room

Drug cannot be used in MDS:

Letrozole

Which of the following medication can be put together in the same ward?

Furosemide and warfarin

Which medicine can be stored in same compartment?

Warfarin & (ACEls or BB can't remember exactly)

The medicine which can't be manipulated by bare hands as that cause skin irritation

Chlorpromazine

Cytotoxic drug, what's the least thing to be concerned about?

Contaminated bench

Precaution while handling Methotrexate tablet

Use Hand glove

Pharmacy has a new system called Monitor Dosage System. What drug should is appropriate to include in this?

Candesartan

Patient is supposed to take clonazepam, but given carbamazepine, he is under care but no side effects, which category of error is this?

Category D

Patient took one dose of a drug. Bo harm but requires monitoring, which error

Category D

patient supposes to take some medicine but took the other medicine, which cause no harm. What type of error is this:

Pt. was admitted to emergency because of side effects to wrong med. a. Which category of error:

An error occurred but the error didn't reach the patient. This error can be categorized as.

Category B

Which of the following strategies can reduce chemotherapeutic medications errors?

Pharmacist who verify chemo order should calculate dose

patient brought a drug back to pharmacy because it was not effective. After inspection it was found to be expired. What is the least to be done, if any, to ensure this won't happen again?

Nothing to be done its human (manual) error can't be prevented

which of the following is not a way to reduce medication misuse?

Advocating use of unapproved abbreviations

All medicines Expiry should be checked regularly and while receiving and dispensing of medicines

Which of the following represent medication error F

Pharmacist dispense losartan instead of another drug and cause dizziness and hospitalized

Which of the following represent medication error F?

Patient take bisoprolol 5 mg instead of Bisacodyl 5mg, and admitted to the hospital because he experienced dizziness

A pediatric patient who was recovering from brain tumor surgery is given 650 mg dose of Methotrexate into the brain. what kind of error is this?

Wrong Dose

Which one of the following is considered a dangerous abbreviation?

IU for international unit

A prescription with Amoxicillin 5ml OD, the best way to write the directions ?

5 ml 1 teaspoonful 1 time daily

Contact the clinic to call the prescriber

prescription error, you are calling the GP but he is not answering what will you do

call the clinic of the Gp and ask them to contact the Gp

What is the best way to write the dose for Digoxin 0.25mg? or Best way of prescribing Digoxin 0.25 mg to avoid error ?

250 mcg

Pharmacy has a new system, after 2 days of it, the pharmacist discovered he made mistak because he doesn't know about the system what to do?

Ask colleague to teach him

Biweekly means: Biweekly Rx for monoclonal antibodies, what to do?

Once every 2 weeks (every other week)

A diabetic pt with HTN and dyslipidemia was ordered to take aspirin 81 and bisoprolol 5 mg and lisinopril 20 and atorvastatin 40 and metformin 1g what is the medication error the doctor made?

BB MASK THE HYPOGLYCEMIC EFFECT

The prescription is legally invalid

Which of the following circumstances would not require the pharmacist to complete a “medication error “ reporting form ; should they become aware of the incident

non-medical prescriber prescribing azathioprine without first completing TPMT test

What is not a potential concern for recording a Medication error?

Patient does not take levothyroxine at home

Clopidogrel, aspirin and cholecalciferol

Hold the infusion for 60 minutes, then resume with 1000 units/hour.

following parenteral anticoagulants require routine monitoring of coagulation lab parameters?

UFH intravenously

Which of the following P2Y12 receptor inhibitors exhibit the most variable anti-platelet effects?

Clopidogrel

Stroke or previous TIA transient ischemic attack is a contraindication to the use of which anti-platelet agent?

Prasugrel

The physician is asking the pharmacist about when to discontinue clopidogrel before open- heart surgery. What should the pharmacist suggest?

Discontinue 5 days before surgery.

Enoxaparin 40 mg SC every 24 hours

Chewable aspirin 81 mg daily

Patient female with food poisoning and went to hospital with troponin high NSTMI what is the management

aspirin 81 mg + ticagrelor

Which PPI is safe with clopidogrel?

Pantoprazole

The least interaction producing PPI with clopidogril

Pantoprazole

A 55-year-old man with myocardial infarction presents to the clinic with dyspnea interrupting his daily activity. Which of the following medications can cause it?

Ticagrelor

Mother came with child ingested a drug by mistake & having symptoms (nausea & vomiting blood). Test results showed he had metabolic acidosis & leukocytosis. Which of the following is the cause?

aspirin

Aspirin overdose symptom

hyperthermia

Aspirin overdose symptoms are all the following except:

Hypothermia

What is the appropriate mode of taking chewable aspirin tablet

Can be chewed or swallowed.

In patients who require dual antiplatelet therapy, what is the recommended maintenance dose of aspirin when used in combination with ticagrelor?

81 mg

Inpatient with MI taking 5 drugs (prasugrel, bisoprolol, aspirin, & another 4th), upon discharge he found only 4 drugs what is the missing one?

Ramipril

Which NSAID permanently inactivates thromboxin-A2 synthesis in platelets?

Aspirin

Minimum of 5 days of heparin and INR greater than 2.0

Which of the following could lead to decrease PT/INR in a patient on warfarin therapy?

Initiation of phenytoin, carbamazepine, or rifampin

patient is on warfarin for mechanical mitral valve replacement. What should be the INR goal range

2.5-3.5

The patient is taking warfarin and the doctor prescribed fluconazole. The patient came with INR=11 and he’s bleeding. What is the reason of this bleeding?

Fluconazole is an enzyme inhibitor & causes warfarin to accumulate in the blood without metabolizing it.

A patient on warfarin presents with nose bleeding since yesterday. His INR=10, what should be the pharmacist's advice?

Stop warfarin and administer vitamin k till patient’s INR is less than 5

Take vitamin K Stop warfarin and give vit. K till patients inr is less than 5

Which of the following is an important counseling point for patients starting on warfarin?

Keep intake of green leafy vegetables.

Antiarythmic drug that increases warfarin toxicity?

Amiodarone Quinidine

What is the monitoring parameter for warfarin therapy?

INR

Phototoxic drug?

Amiodarone

Patient on amiodarone and other drugs. She started to have palpitations, anxiety, and wight loss. Which drug is associated with her condition?

Hyperthyroidism caused by amiodarone

Patient having high TSH levels. She was taking drugs including amiodarone and ibuprofen. Which drug is associated with her condition?

Amiodarone

Amiodarone-induced hypothyroidism

Which of the following antiarrhythmic drugs may cause iodine induced hypothyroidism?

Amiodarone

What is a rare type of adverse drug reaction?

hyperthyroidism from Amiodarone

Which of the following is a rare side effect of amiodarone (less than 1%)):

Peripheral edema

Amiodarone side effect -common

Hypothyroidism

Which of the following is a rare side effect of amiodarone

hyperthyroidism

Which one of the following medications is known to induce pulmonary toxicity?

Amiodarone

At what time should the routine plasma samples for digoxin monitoring be drawn?

6 hours post-dose

62.5 mcg

Which is the anticoagulant preferred during hemodialysis procedure?

Unfractionated heparin

Which one of the following is known side effect of unfractionated heparin?

Hyperkalemia

Glucagon may be used and as an antidote for which of the following?

Metoprolol

Furosemide 40 mg daily

Heparin is chemically bonded to catheters to prevent

Thrombogenicity

Continue titrating the ACEI

A 65-year-old man with NYHA class-IV heart failure has been started on digoxin to improve his symptoms. Which of the following electrolyte imbalances will predispose him to digoxin toxicity?

Hypercalcemia

Verapamil

20 mg

Decrease lisinopril dose

Amlodipine 5 mg with Lisinopril 10 mg in one pill, daily

Metoprolol may mask symptoms of hypoglycemia except for sweating

Prescription containing Frusemide, Bisoprolol, Lisinopril the Disease is?

Stop candesartan, aspirin and ibuprofen

100

The result of one patient revealed hyperkalemia and might escalate to arrhythmia. Her current medications are ff… What predisposed her to this complication?

Eplerenone and Ramipril