問題一覧
1
A 34-year-old woman presents to the physician with upper respiratory infection. Several years ago, she experienced an episode of hypotension and bronchospasm following ampicillin IV administration. What would be the most appropriate empirical therapy?
Erythromycin
2
Patient has community acquired pneumonia; he is sensitive almost she meant allergic not sensitive to flucloxacillin which of the following most appropriate drug?
Azithromycin
3
A patient were having a history of hypersensitivity reaction with flucloxacillin having pneumonia Which antibiotic can be used
clarithromycin
4
Diabetic patient came with complaints of swollen foot wound with redness and hot. he is a farmer working in the field, he is allergic to penicillin antibiotic, and his renal clearance is 70ml/hr. he wants to continue working what will be the best advice to him
Refer him to the Emergency department or Assist him to the acute care immediately without giving any pain reliever
5
The doctor ruled out it was a mild infection. What is the suitable antibiotic-in no penicillin allergy?
Co-amoxiclav
6
Which antibiotic is suitable for this patient penicillin allergy?
Clindamycin
7
he is allergic to tetracycline, erythromycin sensitivity , amoxiclav and other antibiotic from ampicillin group allergy.
erythromycin iv for 7 D
8
The culture report came after three days as given below . Which of the following action is preferable?
Discontinue the antibiotic and start one of sensitive antibiotic
9
Which of the following action is preferable?
Administer Doxycycline 200mg, then Doxycycline 100 mg on daily basis for 5days
10
A 55-year-old woman presents with recurrent symptoms of H. pylori infections. She was previously treated with the classical amoxicillin, clarithromycin, omeprazole regimen. The clinic is unable to obtain susceptibility testing for the Helicobacter pylori but the pattern of local antimicrobial resistance is well known. What would be the optimal treatment for her?
Bismuth subsalicylate (2) and Tetracycline (500 mg) QID plus Metronidazole (500 mg) and Omeprazole (40 mg) BID for 14 days
11
Amoxicillin, Clarithromycin and Omeprazole what the patient suffering from?
H. pylori
12
A 39-year-old woman presents with complain of epigastria burning and pain for the last 6 month 33 / 272 significant medical history but reports an allergy to beta-lactam antibiotics. An office based Urea Breath Test is performed to diagnose Helicobacter pylori infection (see lab result).Test Result :Urea breath test Positive Which of the following is the most appropriate treatment regimen?
Omeprazole, clarithromycin, and metronidazole for 14 days
13
A 28-year-old expectant mother who is diagnosed with Group B hemolytic Streptococcus and has received three doses of ampicillin during labor, delivery is through natural means. Routine examinations of baby show high grade fever, jaundice, and signs of respiratory distress. What would be the optimal empiric antibiotic treatment?
Ampicillin and Gentamicin
14
Women during pregnancy took high doses of ampicillin and after birth, the baby has high bilirubin. What is your intervention
No antibiotic needed
15
AA neonate patient presents with meningitis, what is the appropriate treatment?
Ampicillin + Gentamicin
16
A60 yo patient presents with meningitis, what is the appropriate treatment?
Ceftriaxone + Vancomycin + Ampicillin
17
ACase about a pregnant lady diagnosed with B streptococcus and was taking ampicillin. The baby born with fever and respiratory depression. What meds you will give.
ampicillin-gentamicin
18
A23-month-year-old, 14-kg infant, her mom brought her the hospital with signs and symptoms of bacterial meningitis. The baby attends day care and has a history of acute otitis media. A blood and CSF culture were ordered and pending Which of the following is the empirical therapy for acute bacterial meningitis"
Ceftriaxone or cefotaxime plus vancomycin
19
Which of the following patient categories the gentamicin extended interval regimens (once daily dosing) is most suitable?
Gram-negative infections
20
In a hemodynamically stable patient, when it is recommended to draw gentamicin trough level?
At steady state before the fourth dose
21
What is the best time to do peak levels of gentamicin?
One hour post-dose
22
Patient taking gentamicin, which of the following are increased side effects:
Increased thirst must be report to doctor
23
What would be the most suitable time to do the peak levels of Vancomycin?
1 hour after the 1st dose
24
A 62-year-old man has been admitted in the surgical ward for 14 days and it's suspected to have methicillin-resistant staphylococcus aureus infection (MRSA) in his wound. He is started on Vancomycin 1500 mg IV as a loading dose followed by 1000 mg every 12 hours. he has normal renal function, and his weight is 70 kg. What is the recommended time to take Vancomycin serum levels? Means trough
30 min After the 3rd dose
25
440mg of Gentamicin was given as IV infusion to a pt. yesterday. The nurse checked the drug levels and it was 2 mg/ml today. What will you do?
Call and confirm the time of administration to the nurse
26
A 15-year-old boy or 15 month is brought to the Emergency Department by his parents with high grade fever, vomiting, and non-balancing rash. He started immediately on cefotaxime. The cerebral spinal fluid culture reveals Neisseria meningitis. What would be the recommendation regarding prophylaxis of his family and close contacts?
Patient's close contacts should receive rifampicin
27
Patient is prescribed antibiotic, but he has risk for tendon rupture. Which antibiotic he should not take:
ciprofloxacin & ofloxancin
28
Achilles Tendinitis causing drugs?
ciprofloxacin , ofloxacin
29
38-year-old man with invasive aspergillosis is receiving voriconazole. Which of the following disease states warrant dose adjustment?
Hepatic cirrhosis
30
54-year-old man with history of cirrhosis and alcoholic liver disease presents with hepatic encephalopathy, what is the best treatment option?
Lactulose
31
When given ethambutol for a long duration, continuous follow up/ checkup is necessary because of this condition:
Optic neuritis
32
Which of the following may cause optic neuritis?
Ethambutol
33
Side effect of trimethoprim
Nephrotoxicity
34
A 61-year-old woman with RA experienced Progressive central vision loss and scotoma affecting her reading ability, A fundus examination showed bilateral bull’s eye maculopathy. Which drug likely to cause this SE?
Hydroxychloroquine
35
Avoidance of consuming tyramine-containing food is recommended with which of the following medication.
Linezolid
36
Which of the following is an irreversible side effect of an aminoglycoside?
ototoxicity
37
Patient was taking mesalamine. Few days later he developed nausea and vomiting, palpitation, and flushing. After asking him he reveled that he drinks 2 cups of wine update red wine. The bottle of the medication was inspected and upon comparison of mesalamine tablets shape you discover it was another drug. What is that drug:
Metronidazole
38
Upon inspecting the bottle of medication and discovering that the tablets inside have a different shape from mesalamine, and considering the patient's symptoms of nausea, vomiting, palpitation, and flushing after consuming wine, what is the likely drug that was mistakenly dispensed?
Metronidazole
39
Patient on amiodarone and metformin. He had mild diabetic infection and the physician prescribed clarithromycin. What you will advice the doctor:
There is interaction between amiodarone & clarithromycin so it shall be changed to another antibiotic e.g. flucloxacillin
40
Patient is on Metformin and Amiodarone, prescribed him Clarithromycin upon calling doctor he mentioned that clarithromycin prescribed him for mild infection. What will you advice doctor?
There is interaction and Clarithromycin should be changed to flucloxacillin
41
Amoxicillin prescription with dose of 500 mg 3 times daily for 28 days. What is the most appropriate response?
Confirm the indication with the physician
42
Prescription with amoxicillin 1 gm 3 time a day for 28 day
you should know the condition of pt before dispense
43
One of these is resistant to penicillinase enzyme:
flucloxacillin
44
A patient came as representative for his father that he has Severe Pneumonia. Physician advised for new drug inhalation therapy. He gave his father the new medicine by nebulizer. But his father developed severe bronchoconstriction after using the drug. What counselling will you give to the patient?
Colistimethate sodium is produce bronchoconstriction while doing inhalation therapy to avoid this it has to be mixed with bronchodilator
45
Which of the following is the most suitable method of drug delivery for infants?
Neutralizers
46
Patient with COPD is taking tiotropium, the pharmacist know that he should add another drug (smth like that) what he should choose?
Theophylline
47
When considering an additional medication for a patient with COPD who is already taking tiotropium, which option would be suitable?
Theophylline
48
In COPD patients what medication should ipratropium be administered with?
Albuterol (SALBUTAMOL)
49
Patient is taking b-agonist and ICS for COPD and he had oral thrush. What is the proper technique to avoid it:
wash and gargle with water after use (wash mouth with water after each inhalation)
50
What is likely to cause oral candidiasis .......
the inhaled corticosteroids and possible poor inhaler
51
Patient is taking b agonist and ICS for COPD and he had oral thrush, what is the least proper advise
Oral thrush is normal while using Corticosteriods
52
A asthma patient taking inhaled SABA and corticosteroid and he developed oral thrush and treated with fluconazole what would be the NOT an appropriate counselling to this patient
Oral thrush is normal while using Corticosteriods
53
What is likely to cause oral candidiasis .......
the inhaled corticosteroids and possible poor inhaler
54
Patient is taking b agonist and ICS for COPD and he had oral thrush, what is the least proper advise
Oral thrush is normal while using Corticosteriods
55
asthma patient taking inhaled SABA and corticosteroid and he developed oral thrush and treated with fluconazole what would be the NOT an appropriate counselling to this patient
Oral thrush is normal while using Corticosteriods
56
A patient who has asthma...dr. prescribed SABA and ICS...what is the most preferable advice to the patient
Use spacer
57
By using inhaled corticosteroids & short acting beta agonist experience oral thrush. Why?
Due to inhaled corticosteroids
58
A patient came with a prescription of salbutamol, Prednisolone, beclomethasone, amoxiclav . What is the diagnosis?
COPD exacerbation
59
patient is taking Prednisolone, Amoxicillin and Theophylline. What is the diagnosis?
COPD exacerbation
60
COPD patient take Tiotropium and Roflumilast incharged in hospital with heart pulse = 135 What is the rate control used?
Diltiazem
61
A 26-year-old man is coughing up greenish yellow sputum. The doctor thinks it is of viral origin and decides not to prescribe antibiotics. The doctor also recommends that he sees the pharmacist for some cough mixture. Which of the following active ingredients would be best in the cough mixture?
Guaifenesin
62
Mother come to pharmacy with her daughter that has rash in her neck and face. Her mother told you she has measles. The child used to have fever in the past few days, but she seems fine now. What is the best treatment?child is ok and now playing in pharmacy
Calamine lotion
63
What is the MOST common side effect of inhaled corticosteroids ?
Dysphonia (difficulty speaking)
64
Which of the following is the least appropriate in the acute management of this patient.
Oral clarithromycin 500 mg twice a day for 7 days
65
A 16 year-old girl with asthma recently had aroutine laboratory follow up (see lab results) Which medication is most likely to have contributed to her results?
Inhaled short-acting B2 agonist
66
Salbutamol is used in asthma patients due to it:
Short acting B2 agonist
67
Which of the following prescription is with a high concern?
Salbutamol with metoprolol
68
Case about asthmatic pt. before 2 years, he is taking salbutamol 1- 2 puffs pen, it aggregates with exercise, he got asthmatic attack & went to hospital, what is the advice?
Salbutamol 1-2 puffs 10-15 mins before exercise and 1-2 puff in case of symptomatic max 8 puffs a day
69
Patient was admitted to hospital with arrythmia. He took many medications {digoxin and others can't remember}. His potassium levels were 2.5 mmole/L. Which drug is responsible for this abnormality
Salbutamol
70
Which ONE of the following beta-blockers would be LEAST likely to cause bronchospasm in an asthmatic patient at normal doses?
Bisoprolol
71
Patient taking topical corticosteroid nasal spray. What condition is not Contraindicated? Or contraindicated except?
Deviated septum
72
In which condition nasal spray of Steroid is contraindicated
Post nasal surgery until wound healed
73
A patient with asthma was brought to the hospital. She was already taking SABA and ICS for maintenance. However, she feels scared that another attack might cause her medications to not be effective anymore. What drug is the LEAST helpful should she experience another attack?
Theophylline (dose)
74
What drug is the most helpful should she experience another attack?
Ipratropium (dose)
75
Patient with asthma come to emergency with low respiration rate and other symptoms. Sha was taking SABA for 10 years. What is the next medication to give after stabilizing the patient? patient was taking ICS
Long-acting b-agonist
76
Which of the following is long-acting b-agonist:
Formoterol
77
Patient taking SABA and ICS and Montelukast He started to suffer from side effects from montelukast. What is the alternative:
oral zileuton
78
Patient with asthma came to emergency. She was taking SABA & ICS. He started with montelukast recently and caused him symptoms that he cannot tolerate. What is the best alternative for montelukast?
Oral Zileuton
79
A patient prescribed with SABA, Steroids and Montelukast tablet for management of Asthma. Next day patient presented with Severe reaction like Skin irritation etc and identified it as Montelukast allergy, what will you suggest in place of Montelukast
Zileuton
80
Patient age 22 years taking SABA from 10 years and came to emergency department and chest Xray not shown any consolidation what to add to handle
Oral dexamethasone 30mg for 3 dyas
81
A 21-year-old boy came with complaints of shortness of breath he is on Salbutamol inhaler since last 10 years, X-ray show no consolidation, now which drug can be added for managing this condition.
Beclomethasone
82
A 21-year-old boy came with complaints of shortness of breath he is on Salbutamol inhaler since last 10 years, X-ray show no consolidationthe patient becomes stable on the medication but his sleep breaking 3-4 times nighttime what advice will doctor give to the pharmacist.
Change to LABA.
83
patient is on long-acting corticosteroids and bronchodilators (mostly short acting) he still has symptoms at night what to start
Long-acting bronchodilator
84
A 20-year-old male was admitted to ER because of Asthma exacerbation. He has been taking salbutamol for 10 years. He has no consolidation. What is the unrelated drug to give?
Clarithromycin
85
What's the least drug to affect patient with asthma with no infection and no consolidation?
Antibiotics
86
patient with emergency asthma and no fever and xray show consolidation .Which one least appropriate
clarithromycin
87
A 75-year-old man has recently been diagnosed with open angle glaucoma. He is prescribed topical eye drops once daily. He presents to the pharmacy with the prescription for eye drops labeled, "instill one drop daily in both eyes". What would be the best time to administer the eye drops?
At night
88
A 59-year-old woman with a history of bronchial asthma has been diagnosed with open angle glaucoma. The doctor is thinking about prescribing a topical eye drop. What would be the best topical eye drops?
Latanoprost
89
A 79 year-old woman with a history of open angle glaucoma presents to the pharmacy asking for advice on how long to wait between instilling her second eye drops. She has been prescribed two different eye drops and prefers to instill the eye drops when she goes to sleep. How long should she wait to administer the second eye drops?
5 minutes
90
Which is the first line agent to treat glaucoma in pregnancy?
Brimonidine
91
A 29-year-old pregnant woman been recently diagnosed with open angle glaucoma. What would be the treatment of choice?
Topical timolol 0.1 gel once daily
92
Gray baby syndrome produced by:
Chloramphenicol
93
Which one of the following pair represents the characteristic of an ophthalmic preparation?
Sterile and isotonic
94
A 63-year-old woman has recently been started on Levothyroxine 50 mcg/day. The dose is to be titrated based on T4/TSH and symptoms. What would be the optimal time to repeat her thyroid function tests?
4weeks
95
Patient come with prescription of methimazole and mebeverine. You noticed on the system that he was taking carbimazole and loperamide. What are his conditions:
Hyperthyroidism & IBS
96
Patient taking supplements with levothyroxine and her T4 is very low. What supplement is responsible for this:
Calcium carbonate
97
Which of the following is the least cause of hypothyroidism of a patient taking levothyroxine (high TSH (Should know that high TSH) means low T4” hypothyroidism”))?
Grapefruit
98
table of TSH levels become high with what is the most cause?
Levothyroxine with soy milk
99
25-year-old woman on Levothyroxine become pregnant. She now complains of persistent fatigue. What should be done?
Adjust thyroxine dose based on TSH value during the first trimester