haad 2

100問 • 2年前

問題一覧

pregnant woman with hypothyroidism take levothyroxine and start feeling fatigue?

refer to doctor to adjust dose according TSH

25-year-old woman, on thyroxine for hypothyroidism, become pregnant. She now complains of constant fatigued. What is the most proper recommendation?

Adjust thyroxine dose based on serum TSH during the first trimester

A 73-year-old woman has a three-week history of weight loss, heat intolerance, palpitations and tachycardia. On examination she is anxious and has warm extremities. She is not fit for ablative therapy and the doctor wants to try medications instead (see lab results). What would be the best initial choice of drug?

Methimazole

A 43-year-old man is admitted to the hospital with pneumonia. his past medical history includes Addison’s disease for which he takes hydrocortisone (20 mg in the morning and 10 mg in the afternoon). What is the most appropriate action with respect to his steroid dose?

Double hydrocortisone to 40mg in the morning and 20 mg afternoo

Which of the following Which of the following antineoplastic medications is known to cause bone marrow suppression?

Daunorubicin

Which drug can cause agranulocytosis

cytarabine

Which drug can cause agranulocytosis?

darbepoetin

Antineoplastic medications can be given intrathecal

Cytarabine cytosine arabinoside

Patient with breast cancer and hypertension is taking these medications: Tamoxifen, Capecitabine, Ibuprofen and Lisinopril. She/he developed nephrotoxicity as a result. Which drug should NOT be stopped?

Tamoxifen

What is not a side effect of contraceptive pills:

Ovarian cancer

Antiemetic in cancer / antiemetic with capecitabine?

Metoclopramide

What is the recommended hemoglobin target when treating anemia due to chronic kidney disease with epoetin Alfa?

11 g/dL

About Granulocyte colony stimulating factor (G-CSF) administration?

Administer G-CFS 24-72 hrs. after chemotherapy

Chemotherapy patient, being treated by capecitabine. 30% decrease in the neutrophils is noticed, what should be done

Administer G-CFS 24-72 hrs. after chemotherapy

Administer 5 microgram g-csf after 24-72 hrs of chemotherapy .Breast cancer inpatient in the ward treated with cytarabine . prescribed Iv morphine 10 mg every 4 hours , doctor today discharge her so need to convert to oral morphine :How many mg oral morphine needed ? The same patient suffer from vomiting . what is the anti-vomiting

Prochlorperazine

Which of the following antineoplastic medications can be administered intrathecally?

Cytosine arabinoside

A 55-year-old man is prescribed simvastatin for hyperlipidemia. He is already taking verapamil for hypertension. What should be the maximum dose of simvastatin to be prescribed?

10mg

A 68-year-old woman with a history of type-2 diabetes and dyslipidemia is on atenolol and lisinopril. The doctor has started simvastatin as her estimated 10-year ASCVD risk is 7.5%. What would be the recommended dose for simvastatin?

20 mg

A patient was prescribed atorvastatin, amlodipine, and another drug {can't remember}. What is appropriate counselling?

If you have any muscle pain or myopathy you should report it

A drug that causes serious interaction with simvastatin

Amiodarone

Simvastatin interacts with?

Grapefruit

Which one of the following medications is known to be a powerful enzyme inducer?

Rifampicin

Patient went to pharmacy complaining of severe muscle pain. She said that she was prescribed to take lansoprazole 2 weeks for GERD. The pharmacist inspected her previously dispensed medications and saw Salbutamol and Simvastatin. What caused this symptom to appear to the patient?

Adverse effect of Simvastatin

Patient of arrhythmia and hyperlipidemia take simvastatin , Digoxin , phenytoin for epileptic episodes . He suffer from Fatigue and …… : the cause is

symptoms from simvastatin

Which of the following is a high intensity statin?

Atorvastatin 40 mg HS

Which of the following is a high intensity statin?

Rosuvastatin 20 mg once daily

the pharmacological category for insulin lispro?

Rapid-acting insulin

Which of the following is rapid acting insulin (Doctor prescribed 10 IU Three times a day Which of the following)

Humalog

Patient come to you with hypoglycemia. When you see the prescription, it was written Insulin Gl 10.0 U. What is the least reason to cause his condition?

Insulin was not stored in the refrigerator was stored in room temperature

Patient taking metformin 500 twice daily, long acting insulin one dose, short acting insulin 3 times daily. His blood glucose levels are not under controlled. He did not change his lifestyle or diet. What is your advice:

Ask prescriber to increase metformin dose to 3 times daily

Type 1 diabetic patient did a glucose test in the afternoon, but the result is not up yet. He came to your pharmacy and asked a chair to sit because he has lightheadedness and dizziness. He told you he had his lunch but didn’t check his blood glucose. What is the least correct about his glucose levels?

Fasting glucose 4, glucose level 9 before lunch

plasm glucose level 5 in the morning and 3 after lunch

52 Year type1 diabetes. In the morning feel fatigue and drowsiness . he take insulin before meals and before dedtime . What is the least cause for these symptoms :

Fasting blood glucose 5 and blood glucose level 9 before lunch

A patient is taking long-acting insulin 16U in the morning and ultrashort acting insulin 3U three times in a day. But the patient HbA1C found to be 7.6% and he showed the every recorded FBS and PPBS which were also high. what is the most advice can be given to the patients

Insulin dose should be titrated according to the day-byday sugar level.

A patient Fasting blood sugar found 3.5millimol/Liter. He is taking insulin what would be the preferable advice that can be given by the pharmacist

The preferable maintenance of blood glucose level should be between 4-6 millimol/liter

Patient come to you with hypoglycemia. His fasting blood glucose level was 3.5 mmole/L. He is taking insulin. What is the most appropriate advice?

Insulin dose should be adjusted so that the normal glucose level will be between 4-7 mmole/L

An 18 year-old boy, weighing 60 kg, is diagnosed with type I diabetes. He is prescribed a basal/bolus insulin regime of 0.5 U/kg to mimic physiological levels of insulin as closely as possible. Which would be the most appropriate initial basal insulin regimen?

15 units of insulin Glargine once daily

Patient is your regular customer, it’s her 3rd time tjis mont for clotrimazole. She is silent and always in hurry What as a pharmacist you will do / May be this is the cause.. yes, diabetic patients prone to infections: Patient came to dispense clotrimazole. You noticed that had dispensed it many times in the past few months. She is diabetic and hypertensive. She is taking gliclazide and amlodipine. What is the most appropriate advice?

Ask physician to monitor her blood glucose. It may cause repeated thrushes

A patient came to Pharmacy for Clotrimazole ointment while checking her record found that she is taking this medicines from last two -three month and she also taking Metformin and last review with doctor was 6 months ago. What would be the best counselling to the patient?

The infection may be due to poor glycemic control and take a review with physician.

Patient taking linagliptin, amlodipine, ibuprofen, other form aspirin ramipril. His creatinine clearance become low. What medication you think he should stop, if any:

Ramipril, ibuprofen

Pt was take ramipril, aspirin,linagliptin . Her gfr 25ml/min What should stop?

ramipril and aspirin

Which of the following anti-diabetic medications should be used as a first line agent in patients with pre-diabetes?

Metformin

Who is contraindicated to use amorolfine nail lacquer?

Patient with diabetes

Which drug should not be given to patients with reduced ejection fraction?

Pioglitazone

Which of the following strategy can be recommended to reduce metformin associated gastrointestinal side effects?

Administer in divided doses with meals

A 65-year-old man was diagnosed with Type II DM 5 years ago and he is on oral biguanides. His routine follow ups and laboratory workup is scheduled. Which of the following additional tests is recommended?

Vit B12

A 55-year-old man with a BMI of 37 is diagnosed with Type II diabetes three months ago. He failed to adhere to prescribed diet and exercise regimen. Which of the following medications would be best indicated?

Metformin

Patient with diabetes with a list of drugs & asking about drug which may have the highest SE for him (they mentioned that he receives many synergistic drugs)?

Gliclazide

Patient taking glipizide and is having hypoglycemia episodes what to do

add metformin to produce normoglycemia

Patient taking gliclazide and is having hypoglycemia episodes what to do :

switch to another sulfonylurea

patient taking synergistic medicine for diabetes. What medicine will be danger for him...

Sulfonylurea

patient with DM treated with 2 types (synergestic treatment ) of sulfonyl groups . which drug is CI to this patient???

atenolol

Drug of choice for gestational diabetes

Insulin

Produce precipitate with phenytoin:

Dextrose

Phenytoin prepared with

NaCl (Normal Saline)

Phenytoin crystalizes. Because of what

cyclizine

Phenobarbital precipitate with?

Sterile water or dextrose 50%

What is the caution when prepare potassium solution?

Diluted with huge amount of water

Drugs with pka =5 absorption site?

Duodenum

At which pH aspirin (pka 3.5) will be most soluble?

Why ophthalmic suspension should not be freeze?

It will make crystallization

Pharmacist preparing IV preparation by mixing Cyclizine, Dexamethasone and NS 0.9% by using aseptic technique, after few minutes the mixture become cloudy. The PH of each preparations are 3, 5.5 and 7 respectively, what would be the cause of precipitation

Use of Normal saline

patient came to pharmacy for insulin, while talking with her she revealed that she used to store Insulin in freezer, how would you counsel the patient regarding the storage of insulin in freezer causes crystallization and total loss of activity

The freezer temperature will lead to the precipitation of insulin

A lady bike has diabetic, she used to travel by carrying insulin in her bike by using ice pack, once she complained about precipitation of Insulin what would be the cause.

Ice packs were in direct contact with medicine

What happens when insulin gets accidentally frozen?

Precipitation happens

Filgrastim was diluted with 500ml instead of 1000 ml. cloudy solution appears. What is the cause:

Precipitation

A company make a product for colon cancer, its easily absorbed from the intestine , which statement is not concern with the drug

use of HPMC as coating

Which of the following is the least to be used in a medication for colon cancer?

HPMC coating

A new active ingredient for ulcerative colitis has been identified it needs to be absorbed in the intestine to be effective. Which of the following formulation strategies would Not be effective at delaying absorption until the active ingredient reach the intestine

The product should be formulated in a hydroxypropyl methylcellulose (HPMC) coating

Which dosage form is appropriate when maximum moisturization is required?

Ointment

Which of the following medications can be used to lower the elevated serum potassium concentration?

Kayexalate

What is the bioavailability (F) of a diclofenac intramuscular injection?

Approximately 100%

Patient is allergic to preservatives what base is suitable to use to make sublingual preparation:

Anhydrous base

Hygroscopic substance needs to be coated what is the least suitable material to use:

Calcium chloride

Which of the following is enzyme inducer: (all are enzyme inhibitor except)

Carbamazepine

Double wrapping required for ?

hygroscopic

Which of the following bases can be used to prepare rectal suppositories?

Cocoa butter

Potassium chloride administration:

Dilute in infusion and mix to avoid layering

Dimethicone mechanism of action:

Interfere with water balance

the way permethrin works is by over-exciting an insect nervous system. When an insect encounters permethrin, it becomes paralyzed and in this weakened state, the insect generally disengages, falls off, and frequently dies. What is the reason of death?

Makes paralysis leading to death

New nurse is giving adolescent injection in gluteus muscle and doesn’t know what is maximum volume of injection

5ml

Most suitable form of infants

Syrup

Administration of BOTOX injection

Least preferred rout for peptide/protein administration

Oral

One of this is a weak electrolyte:

creatinine

Which of the following replacement solution is isotonic?

Ringer’s lactate

Depot injection is administered by.

A patient has allergic reaction. He has very short bowel. The physician prescribed prednisolone enteric coated tablet. What is your advice to the physician?

Change to prednisolone original (standard) tablet

Patient is taking methotrexate and is known to be excreted 90% unchanged in the urine. Methotrexate levels diminish at 96 hours. What might be the cause of prolonged excretion of this drug?

Increased fluid in body due to effusion

In which one of the following conditions estrogens containing contraceptive is contraindicated?

40-year-old women who smoke

A 52 female suspected to have osteoporosis. She has hot flushing and undergoes hysterectomy. What is the most appropriate treatment?

unopposed estrogen

the content of monophasic contraceptive pill?

Constant dose of estrogen and progesterone

Monophasic contraceptive

pills deliver the same amount of estrogen and progestin each day for 21 days

A woman on mycophenolate is planning for pregnancy. She is asking for pharmacist advice, what should be the appropriate advice?

Mycophenolate should be discontinued at least 6 weeks prior to trying to conceive.

A 27-year-old pregnant woman has been recently diagnosed with iron deficiency anemia. Her hemoglobin is less than 11 g/dl. What would be the best recommended?

Ferrous sulphate tablets on an empty stomach

Which one of the following is an important counselling point for woman starting on Fingolimod (treat relapsing of MS)?

Must use effective contraception to avoid pregnancy during and for 2 months aftertreatment.

Which of the following medications require observing the patient for six hours with hourly heart rate monitoring after the first dose?

Fingolimod

What is Which medication requires negative pregnancy test before dispensing to woman of childbearing age?

Isotretinoin

Which of the following medications can be teratogenic if a pregnant women handles crushes or breaks the tablet?

Bosentan

100

What is the most important ingredient in maternal multi-vitamin products?

Folic acid

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ユーザ名非公開 · 12回閲覧 · 100問 · 2年前

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問題一覧

pregnant woman with hypothyroidism take levothyroxine and start feeling fatigue?

refer to doctor to adjust dose according TSH

25-year-old woman, on thyroxine for hypothyroidism, become pregnant. She now complains of constant fatigued. What is the most proper recommendation?

Adjust thyroxine dose based on serum TSH during the first trimester

Methimazole

Double hydrocortisone to 40mg in the morning and 20 mg afternoo

Which of the following Which of the following antineoplastic medications is known to cause bone marrow suppression?

Daunorubicin

Which drug can cause agranulocytosis

cytarabine

Which drug can cause agranulocytosis?

darbepoetin

Antineoplastic medications can be given intrathecal

Cytarabine cytosine arabinoside

Tamoxifen

What is not a side effect of contraceptive pills:

Ovarian cancer

Antiemetic in cancer / antiemetic with capecitabine?

Metoclopramide

What is the recommended hemoglobin target when treating anemia due to chronic kidney disease with epoetin Alfa?

11 g/dL

About Granulocyte colony stimulating factor (G-CSF) administration?

Administer G-CFS 24-72 hrs. after chemotherapy

Chemotherapy patient, being treated by capecitabine. 30% decrease in the neutrophils is noticed, what should be done

Administer G-CFS 24-72 hrs. after chemotherapy

Prochlorperazine

Which of the following antineoplastic medications can be administered intrathecally?

Cytosine arabinoside

A 55-year-old man is prescribed simvastatin for hyperlipidemia. He is already taking verapamil for hypertension. What should be the maximum dose of simvastatin to be prescribed?

10mg

20 mg

A patient was prescribed atorvastatin, amlodipine, and another drug {can't remember}. What is appropriate counselling?

If you have any muscle pain or myopathy you should report it

A drug that causes serious interaction with simvastatin

Amiodarone

Simvastatin interacts with?

Grapefruit

Which one of the following medications is known to be a powerful enzyme inducer?

Rifampicin

Adverse effect of Simvastatin

Patient of arrhythmia and hyperlipidemia take simvastatin , Digoxin , phenytoin for epileptic episodes . He suffer from Fatigue and …… : the cause is

symptoms from simvastatin

Which of the following is a high intensity statin?

Atorvastatin 40 mg HS

Which of the following is a high intensity statin?

Rosuvastatin 20 mg once daily

the pharmacological category for insulin lispro?

Rapid-acting insulin

Which of the following is rapid acting insulin (Doctor prescribed 10 IU Three times a day Which of the following)

Humalog

Patient come to you with hypoglycemia. When you see the prescription, it was written Insulin Gl 10.0 U. What is the least reason to cause his condition?

Insulin was not stored in the refrigerator was stored in room temperature

Ask prescriber to increase metformin dose to 3 times daily

Fasting glucose 4, glucose level 9 before lunch

plasm glucose level 5 in the morning and 3 after lunch

52 Year type1 diabetes. In the morning feel fatigue and drowsiness . he take insulin before meals and before dedtime . What is the least cause for these symptoms :

Fasting blood glucose 5 and blood glucose level 9 before lunch

Insulin dose should be titrated according to the day-byday sugar level.

A patient Fasting blood sugar found 3.5millimol/Liter. He is taking insulin what would be the preferable advice that can be given by the pharmacist

The preferable maintenance of blood glucose level should be between 4-6 millimol/liter

Patient come to you with hypoglycemia. His fasting blood glucose level was 3.5 mmole/L. He is taking insulin. What is the most appropriate advice?

Insulin dose should be adjusted so that the normal glucose level will be between 4-7 mmole/L

15 units of insulin Glargine once daily

Ask physician to monitor her blood glucose. It may cause repeated thrushes

The infection may be due to poor glycemic control and take a review with physician.

Patient taking linagliptin, amlodipine, ibuprofen, other form aspirin ramipril. His creatinine clearance become low. What medication you think he should stop, if any:

Ramipril, ibuprofen

Pt was take ramipril, aspirin,linagliptin . Her gfr 25ml/min What should stop?

ramipril and aspirin

Which of the following anti-diabetic medications should be used as a first line agent in patients with pre-diabetes?

Metformin

Who is contraindicated to use amorolfine nail lacquer?

Patient with diabetes

Which drug should not be given to patients with reduced ejection fraction?

Pioglitazone

Which of the following strategy can be recommended to reduce metformin associated gastrointestinal side effects?

Administer in divided doses with meals

Vit B12

Metformin

Patient with diabetes with a list of drugs & asking about drug which may have the highest SE for him (they mentioned that he receives many synergistic drugs)?

Gliclazide

Patient taking glipizide and is having hypoglycemia episodes what to do

add metformin to produce normoglycemia

Patient taking gliclazide and is having hypoglycemia episodes what to do :

switch to another sulfonylurea

patient taking synergistic medicine for diabetes. What medicine will be danger for him...

Sulfonylurea

patient with DM treated with 2 types (synergestic treatment ) of sulfonyl groups . which drug is CI to this patient???

atenolol

Drug of choice for gestational diabetes

Insulin

Produce precipitate with phenytoin:

Dextrose

Phenytoin prepared with

NaCl (Normal Saline)

Phenytoin crystalizes. Because of what

cyclizine

Phenobarbital precipitate with?

Sterile water or dextrose 50%

What is the caution when prepare potassium solution?

Diluted with huge amount of water

Drugs with pka =5 absorption site?

Duodenum

At which pH aspirin (pka 3.5) will be most soluble?

Why ophthalmic suspension should not be freeze?

It will make crystallization

Use of Normal saline

The freezer temperature will lead to the precipitation of insulin

A lady bike has diabetic, she used to travel by carrying insulin in her bike by using ice pack, once she complained about precipitation of Insulin what would be the cause.

Ice packs were in direct contact with medicine

What happens when insulin gets accidentally frozen?

Precipitation happens

Filgrastim was diluted with 500ml instead of 1000 ml. cloudy solution appears. What is the cause:

Precipitation

A company make a product for colon cancer, its easily absorbed from the intestine , which statement is not concern with the drug

use of HPMC as coating

Which of the following is the least to be used in a medication for colon cancer?

HPMC coating

The product should be formulated in a hydroxypropyl methylcellulose (HPMC) coating

Which dosage form is appropriate when maximum moisturization is required?

Ointment

Which of the following medications can be used to lower the elevated serum potassium concentration?

Kayexalate

What is the bioavailability (F) of a diclofenac intramuscular injection?

Approximately 100%

Patient is allergic to preservatives what base is suitable to use to make sublingual preparation:

Anhydrous base

Hygroscopic substance needs to be coated what is the least suitable material to use:

Calcium chloride

Which of the following is enzyme inducer: (all are enzyme inhibitor except)

Carbamazepine

Double wrapping required for ?

hygroscopic

Which of the following bases can be used to prepare rectal suppositories?

Cocoa butter

Potassium chloride administration:

Dilute in infusion and mix to avoid layering

Dimethicone mechanism of action:

Interfere with water balance

Makes paralysis leading to death

New nurse is giving adolescent injection in gluteus muscle and doesn’t know what is maximum volume of injection

5ml

Most suitable form of infants

Syrup

Administration of BOTOX injection

Least preferred rout for peptide/protein administration

Oral

One of this is a weak electrolyte:

creatinine

Which of the following replacement solution is isotonic?

Ringer’s lactate

Depot injection is administered by.

A patient has allergic reaction. He has very short bowel. The physician prescribed prednisolone enteric coated tablet. What is your advice to the physician?

Change to prednisolone original (standard) tablet

Patient is taking methotrexate and is known to be excreted 90% unchanged in the urine. Methotrexate levels diminish at 96 hours. What might be the cause of prolonged excretion of this drug?

Increased fluid in body due to effusion

In which one of the following conditions estrogens containing contraceptive is contraindicated?

40-year-old women who smoke

A 52 female suspected to have osteoporosis. She has hot flushing and undergoes hysterectomy. What is the most appropriate treatment?

unopposed estrogen

the content of monophasic contraceptive pill?

Constant dose of estrogen and progesterone

Monophasic contraceptive

pills deliver the same amount of estrogen and progestin each day for 21 days

A woman on mycophenolate is planning for pregnancy. She is asking for pharmacist advice, what should be the appropriate advice?

Mycophenolate should be discontinued at least 6 weeks prior to trying to conceive.

A 27-year-old pregnant woman has been recently diagnosed with iron deficiency anemia. Her hemoglobin is less than 11 g/dl. What would be the best recommended?

Ferrous sulphate tablets on an empty stomach

Which one of the following is an important counselling point for woman starting on Fingolimod (treat relapsing of MS)?

Must use effective contraception to avoid pregnancy during and for 2 months aftertreatment.

Which of the following medications require observing the patient for six hours with hourly heart rate monitoring after the first dose?

Fingolimod

What is Which medication requires negative pregnancy test before dispensing to woman of childbearing age?

Isotretinoin

Which of the following medications can be teratogenic if a pregnant women handles crushes or breaks the tablet?

Bosentan

100

What is the most important ingredient in maternal multi-vitamin products?

Folic acid