phar (Molecular target)
phar (Molecular target)
Hui Suki · 37問 · 2年前phar (Molecular target)
phar (Molecular target)
37問 • 2年前Mechanisms of action of toxins
Mechanisms of action of toxins
Hui Suki · 27問 · 2年前Mechanisms of action of toxins
Mechanisms of action of toxins
27問 • 2年前Chapter 5
Chapter 5
Hui Suki · 6問 · 2年前Chapter 5
Chapter 5
6問 • 2年前Chapter 1
Chapter 1
Hui Suki · 21問 · 2年前Chapter 1
Chapter 1
21問 • 2年前Chapter 3
Chapter 3
Hui Suki · 24問 · 2年前Chapter 3
Chapter 3
24問 • 2年前問題一覧
1
The most dominant enzymes (transferase)
glucuronosyl transferase
2
Phase II enzymes
Glucuronosyl transferase, Sulfotransferase, N-Acetyl transferase
3
Possibility of reaction of drug in phase II
Acyl glucuronidation, O-sulfation, N-acetylation
4
Examples of NSAIDs
Ibuprofen, Aspirin, Naproxen
5
Factors affect. metabolism
Pathological conditions, Age, Diet, Sex, Genetic factor, Drug-drug interaction
6
Inhibition of micosomal enzymes and decrease of metabolism
Competitive inhibition, Non-competitve inhibition, Suicide inhibition
7
Renal clearance
Glomerular filtration, Active tubular secretion, Passive tubular reasorption