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ENZYME OF CLINICAL SIGNIFICANCE-MCQ2
87問 • 1ヶ月前
  • ayrika
    • 通報

    問題一覧

  • 1

    Tartrate sensitive ACP increase due to malignant prostatic epithelial cell release into the bloodstream

    PROSTATIC CARCINOMA

  • 2

    Tartrate sensitive which levels are lower than in carcinoma due to hyperplastic prostatic tissue

    BENIGN PROSTATIC

  • 3

    Tartrate sensitive ACP due to necrosis which is typically transient elevation

    PROSTATIC INFARCTION

  • 4

    Tartrate sensitive ACP due to Stimulation which physiologic and transient

    PROSTATIC MASSAGE

  • 5

    Tartrate sensitive ACP due to back pressure or inflammation

    URINARY TRACT OBSTRUCTION

  • 6

    Tartrate sensitive ACP which is rare and documented due to adjacent prostatic cell

    CARCINOID TUMOR

  • 7

    ACP detected in medico legal cases

    TARTRATE SENSITIVE ACP

  • 8

    Bone ACP due to hyperactive osteoclast

    PAGETS DISEASE, OSTEOPOROSIS, METASTATIC BONE DISEASE

  • 9

    Bone ACP + lipid laden+ macrophage cells

    GAUCHER DISEASE

  • 10

    Bone ACP from malignant b cell

    HAIRY CELL LEUKEMIA

  • 11

    ACP determination: Gutman and Gutman Substrate: End Product

    PHENYLPHOSPHATE, INORGANIC PHOSPHATE

  • 12

    ACP determination: Shinowara Substrate: End Product

    PNPP, P-NITROPHENOL

  • 13

    ACP determination: Babson, Read, and Philips Substrate: End Product

    A NAPHTHYL PHOSPHATE, A NAPHTHOL

  • 14

    ACP determination: Roy and Hillman Substrate: End Product

    THYMOLPHTHALEIN, FREE THYMOLPHTHALEIN

  • 15

    Preferred mehtod for ACP determination

    ROY AND HILLMAN

  • 16

    Assay tehdcnique for the measurement of Prostatic ACP

    CHEMICAL INHIBITION

  • 17

    Endpoint reaction for ACP

    ROY

  • 18

    Continuous monitoring for ACP

    HILLMAN

  • 19

    Preferred susbrate for ACP roy

    THYMOLPHTHALEIN MONOPHOSPHATE

  • 20

    Preffered substrate for ACP Hillman

    A NAPHTHOL PHOSPHATE

  • 21

    Phenylalanine inhibits what ALP

    PLACENTAL, INTESTINAL

  • 22

    Levamisole inhibits what ALP

    BONE

  • 23

    Mehtod to diferentiate Bone and Liver ALP

    CHEMICAL INHIBITION

  • 24

    Method to differentiate Placental, Bone, and Liver ALP

    HEAT FRACTIONATION

  • 25

    Which of these is heat labile ALP

    BONE

  • 26

    Which of these is partially heat stable

    LIVER

  • 27

    Which of these is heat stable

    PLACENTAL

  • 28

    Which of these ALP is lung cancer marker

    REGAN

  • 29

    Which of these ALP is GI adenocarcinoma marker

    NAGAO

  • 30

    Which of these ALP is a rare tumor marker

    INTESTINAL

  • 31

    Method used to differentiate Bone and liver ALP

    ENZYME TREATMENT

  • 32

    Measurement assay for ALP

    BOWERS AND MCCOMB

  • 33

    ALP is stable for __in one week

    4C

  • 34

    Half life of GGT

    7-10 DAY

  • 35

    This serves as inhbitor for the ALP assay

    CHELATING AGENT

  • 36

    GGT can be detected for up to 28 days in

    ALCOHOLIC LIVER DISEASE

  • 37

    This condition may increased GGT for up to 2-5X of its baseline

    CHRONIC ALCOHOL

  • 38

    This medications decreases GGT levels

    ANTI CONVULSANTS

  • 39

    Which of this is a physiologic cause of GGT for up to 25%

    1ST TRIMESTER PREGNANCY

  • 40

    If both ALP and GGT are high

    LIVER SOURCE

  • 41

    If ALP is high but GGT is normal

    BONE DISEASE

  • 42

    Molecular weight of Amylase

    45,000

  • 43

    Activators of AMS

    BROMIDE, CHLORIDE

  • 44

    Which of these metalloenzyme needs AMS for activity

    CALCIUM

  • 45

    Optimal ph for AMS activity

    6.9-7.0

  • 46

    C'mon isoenzymes of AMS

    P1, S1, S2

  • 47

    Fastest migrating AMS

    S1

  • 48

    AMS inhibited bt monoclonal antibodies and wheat protein

    S TYPE

  • 49

    AMS inhibited by monoclonal antibodies but not wheat protein

    P TYPE

  • 50

    Predominant and slowest AMS

    P3

  • 51

    Reference AMS Determination which measures the amount of reducing sugars like maltose

    SACCHAROGENIC, NELSON SOMOGYI

  • 52

    AMS Determination which measures the disappearance of starch reduction in blue color

    IODOMETRIC, AMYLOCLASTIC

  • 53

    AMS Determination which measures release of color from a dye labeled starch substrate

    CHROMOGENIC

  • 54

    AMS determination which measures change in turbidity as starch is hydrolyzed

    TURBIDIMETRIC, NEPHELOMETRIC

  • 55

    Real time monitoring using short oligosaccharide which has higher accuracy and better stoichiometric control

    CONTINUOUS MONITORING

  • 56

    In AMS-Creatinine ratio, urine and serum amylase are in

    U/L

  • 57

    In AMS-Creatinine ratio, urine and serum creatine are in

    MG/DL

  • 58

    A:C ratio of 1-4%

    NORMAL

  • 59

    A:C ratio of <1.0%

    MACROAMYLASEMIA

  • 60

    A:C ratio of >4.0%

    ACUTE PANCREATITIS

  • 61

    Acts only on emulsified fats requiring lipid water interface

    LPS

  • 62

    LPS organ primary source

    PANCREAS

  • 63

    LPS Ddetermination using Long chain triglycerides Fatty acid released are titrated with alkali

    TITRIMETRIC

  • 64

    LPS determination using Long chain triglycerides Uses potentiometric titration

    CHERRY CRANDALL

  • 65

    LPS determination using Long chain triglycerides Enzyme breaks down emulsified fats causing decreased turbidity

    TURBIDIMETRIC

  • 66

    LPS determination using Long chain triglycerides Enzyme diffuses in agarose gel with oil and deoxycholate

    ROSITAL DIFFUSION

  • 67

    LPS determination using Long chain triglycerides Colorimetry after extracting fatty acids with solvents

    SPECTROPHOTOMETRIC

  • 68

    Which of these uses olive oil in LPS determination

    CHERRY CRANDALL, VOGEL AND ZIEVE

  • 69

    Which of these uses triolein for LPS determination

    DUPONT

  • 70

    Fo short chain triglyceride LPS determination, what substrate is used

    TRIBUTYRIN

  • 71

    Which of these can be seen in mumps

    AMS

  • 72

    Which of these is has longer half life

    LPS

  • 73

    Which of these can be used of early diagnosis of Pancreatitis

    AMS

  • 74

    Inhibitors of Trypsin

    A1 ANTITRYPSIN, A2 MACROGLOBULIN

  • 75

    Activator or TRYP

    ENTEROKINASE

  • 76

    This enzyme acts as digestive and cascade initiator

    TRYP

  • 77

    Elevated in acute pancreatitis, chronic renal failure, and cystic fibrosis

    TRYPSIN 1

  • 78

    Rises more significantly in acute pancreatitis especially in urine for about 10x

    TRYPSIN 2

  • 79

    Which of these is a negatively charged

    TRYPSIN 2

  • 80

    Immunochromatographic method using monoclonal antibodies which can used for early detection of pancreatitis marker

    URINARY TRYP 2 TEST STRIP

  • 81

    ELISA based kit or chemiluminescence that detects anti tryp complexes

    IMMUNOASSAY

  • 82

    Elevated tryp+amylase+lipase=

    ACUTE PANCREATITIS

  • 83

    TRYP2>TRYP1 suggest

    ALCOHOL RELATED PANCREATITIS

  • 84

    TRYP1>TRYP2 suggest

    BILIARY ORIGIN

  • 85

    Best for cause classification of pancreatitis

    TRYP

  • 86

    Best for early diagnosis of pancreatitis

    AMY

  • 87

    Best for late pancreatitis detection

    LPS

    • DEMATIACEOUS OPPORTUNISTIC FUNGI

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    PITUITARY GLAND PART 2

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    PITUITARY GLAND PART 2

    PITUITARY GLAND PART 2

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    PITUITARY GLAND PART 2

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    THYROID GLAND

    THYROID GLAND

    ayrika · 71問 · 1ヶ月前

    THYROID GLAND

    THYROID GLAND

    71問 • 1ヶ月前
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    THYROID GLAND

    THYROID GLAND

    ayrika · 71問 · 1ヶ月前

    THYROID GLAND

    THYROID GLAND

    71問 • 1ヶ月前
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    ADRENAL GLAND

    ADRENAL GLAND

    ayrika · 77問 · 1ヶ月前

    ADRENAL GLAND

    ADRENAL GLAND

    77問 • 1ヶ月前
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    SEX GLANDS

    SEX GLANDS

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    SEX GLANDS

    SEX GLANDS

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    OTHER GLANDS

    OTHER GLANDS

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    OTHER GLANDS

    OTHER GLANDS

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    OTHER GLANDS

    OTHER GLANDS

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    OTHER GLANDS

    OTHER GLANDS

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    TOXICOLOGY

    TOXICOLOGY

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    TOXICOLOGY

    TOXICOLOGY

    72問 • 1ヶ月前
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    TOXICOLOGY

    TOXICOLOGY

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    TOXICOLOGY

    TOXICOLOGY

    72問 • 1ヶ月前
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    TOXICOLOGY

    TOXICOLOGY

    ayrika · 72問 · 1ヶ月前

    TOXICOLOGY

    TOXICOLOGY

    72問 • 1ヶ月前
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    DRUG OF ABUSE

    DRUG OF ABUSE

    ayrika · 95問 · 1ヶ月前

    DRUG OF ABUSE

    DRUG OF ABUSE

    95問 • 1ヶ月前
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    DRUG OF ABUSE

    DRUG OF ABUSE

    ayrika · 95問 · 1ヶ月前

    DRUG OF ABUSE

    DRUG OF ABUSE

    95問 • 1ヶ月前
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    TOXINS

    TOXINS

    ayrika · 57問 · 1ヶ月前

    TOXINS

    TOXINS

    57問 • 1ヶ月前
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    TOXINS

    TOXINS

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    TOXINS

    TOXINS

    57問 • 1ヶ月前
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    TDM

    TDM

    ayrika · 94問 · 1ヶ月前

    TDM

    TDM

    94問 • 1ヶ月前
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    TDM

    TDM

    ayrika · 94問 · 1ヶ月前

    TDM

    TDM

    94問 • 1ヶ月前
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    問題一覧

  • 1

    Tartrate sensitive ACP increase due to malignant prostatic epithelial cell release into the bloodstream

    PROSTATIC CARCINOMA

  • 2

    Tartrate sensitive which levels are lower than in carcinoma due to hyperplastic prostatic tissue

    BENIGN PROSTATIC

  • 3

    Tartrate sensitive ACP due to necrosis which is typically transient elevation

    PROSTATIC INFARCTION

  • 4

    Tartrate sensitive ACP due to Stimulation which physiologic and transient

    PROSTATIC MASSAGE

  • 5

    Tartrate sensitive ACP due to back pressure or inflammation

    URINARY TRACT OBSTRUCTION

  • 6

    Tartrate sensitive ACP which is rare and documented due to adjacent prostatic cell

    CARCINOID TUMOR

  • 7

    ACP detected in medico legal cases

    TARTRATE SENSITIVE ACP

  • 8

    Bone ACP due to hyperactive osteoclast

    PAGETS DISEASE, OSTEOPOROSIS, METASTATIC BONE DISEASE

  • 9

    Bone ACP + lipid laden+ macrophage cells

    GAUCHER DISEASE

  • 10

    Bone ACP from malignant b cell

    HAIRY CELL LEUKEMIA

  • 11

    ACP determination: Gutman and Gutman Substrate: End Product

    PHENYLPHOSPHATE, INORGANIC PHOSPHATE

  • 12

    ACP determination: Shinowara Substrate: End Product

    PNPP, P-NITROPHENOL

  • 13

    ACP determination: Babson, Read, and Philips Substrate: End Product

    A NAPHTHYL PHOSPHATE, A NAPHTHOL

  • 14

    ACP determination: Roy and Hillman Substrate: End Product

    THYMOLPHTHALEIN, FREE THYMOLPHTHALEIN

  • 15

    Preferred mehtod for ACP determination

    ROY AND HILLMAN

  • 16

    Assay tehdcnique for the measurement of Prostatic ACP

    CHEMICAL INHIBITION

  • 17

    Endpoint reaction for ACP

    ROY

  • 18

    Continuous monitoring for ACP

    HILLMAN

  • 19

    Preferred susbrate for ACP roy

    THYMOLPHTHALEIN MONOPHOSPHATE

  • 20

    Preffered substrate for ACP Hillman

    A NAPHTHOL PHOSPHATE

  • 21

    Phenylalanine inhibits what ALP

    PLACENTAL, INTESTINAL

  • 22

    Levamisole inhibits what ALP

    BONE

  • 23

    Mehtod to diferentiate Bone and Liver ALP

    CHEMICAL INHIBITION

  • 24

    Method to differentiate Placental, Bone, and Liver ALP

    HEAT FRACTIONATION

  • 25

    Which of these is heat labile ALP

    BONE

  • 26

    Which of these is partially heat stable

    LIVER

  • 27

    Which of these is heat stable

    PLACENTAL

  • 28

    Which of these ALP is lung cancer marker

    REGAN

  • 29

    Which of these ALP is GI adenocarcinoma marker

    NAGAO

  • 30

    Which of these ALP is a rare tumor marker

    INTESTINAL

  • 31

    Method used to differentiate Bone and liver ALP

    ENZYME TREATMENT

  • 32

    Measurement assay for ALP

    BOWERS AND MCCOMB

  • 33

    ALP is stable for __in one week

    4C

  • 34

    Half life of GGT

    7-10 DAY

  • 35

    This serves as inhbitor for the ALP assay

    CHELATING AGENT

  • 36

    GGT can be detected for up to 28 days in

    ALCOHOLIC LIVER DISEASE

  • 37

    This condition may increased GGT for up to 2-5X of its baseline

    CHRONIC ALCOHOL

  • 38

    This medications decreases GGT levels

    ANTI CONVULSANTS

  • 39

    Which of this is a physiologic cause of GGT for up to 25%

    1ST TRIMESTER PREGNANCY

  • 40

    If both ALP and GGT are high

    LIVER SOURCE

  • 41

    If ALP is high but GGT is normal

    BONE DISEASE

  • 42

    Molecular weight of Amylase

    45,000

  • 43

    Activators of AMS

    BROMIDE, CHLORIDE

  • 44

    Which of these metalloenzyme needs AMS for activity

    CALCIUM

  • 45

    Optimal ph for AMS activity

    6.9-7.0

  • 46

    C'mon isoenzymes of AMS

    P1, S1, S2

  • 47

    Fastest migrating AMS

    S1

  • 48

    AMS inhibited bt monoclonal antibodies and wheat protein

    S TYPE

  • 49

    AMS inhibited by monoclonal antibodies but not wheat protein

    P TYPE

  • 50

    Predominant and slowest AMS

    P3

  • 51

    Reference AMS Determination which measures the amount of reducing sugars like maltose

    SACCHAROGENIC, NELSON SOMOGYI

  • 52

    AMS Determination which measures the disappearance of starch reduction in blue color

    IODOMETRIC, AMYLOCLASTIC

  • 53

    AMS Determination which measures release of color from a dye labeled starch substrate

    CHROMOGENIC

  • 54

    AMS determination which measures change in turbidity as starch is hydrolyzed

    TURBIDIMETRIC, NEPHELOMETRIC

  • 55

    Real time monitoring using short oligosaccharide which has higher accuracy and better stoichiometric control

    CONTINUOUS MONITORING

  • 56

    In AMS-Creatinine ratio, urine and serum amylase are in

    U/L

  • 57

    In AMS-Creatinine ratio, urine and serum creatine are in

    MG/DL

  • 58

    A:C ratio of 1-4%

    NORMAL

  • 59

    A:C ratio of <1.0%

    MACROAMYLASEMIA

  • 60

    A:C ratio of >4.0%

    ACUTE PANCREATITIS

  • 61

    Acts only on emulsified fats requiring lipid water interface

    LPS

  • 62

    LPS organ primary source

    PANCREAS

  • 63

    LPS Ddetermination using Long chain triglycerides Fatty acid released are titrated with alkali

    TITRIMETRIC

  • 64

    LPS determination using Long chain triglycerides Uses potentiometric titration

    CHERRY CRANDALL

  • 65

    LPS determination using Long chain triglycerides Enzyme breaks down emulsified fats causing decreased turbidity

    TURBIDIMETRIC

  • 66

    LPS determination using Long chain triglycerides Enzyme diffuses in agarose gel with oil and deoxycholate

    ROSITAL DIFFUSION

  • 67

    LPS determination using Long chain triglycerides Colorimetry after extracting fatty acids with solvents

    SPECTROPHOTOMETRIC

  • 68

    Which of these uses olive oil in LPS determination

    CHERRY CRANDALL, VOGEL AND ZIEVE

  • 69

    Which of these uses triolein for LPS determination

    DUPONT

  • 70

    Fo short chain triglyceride LPS determination, what substrate is used

    TRIBUTYRIN

  • 71

    Which of these can be seen in mumps

    AMS

  • 72

    Which of these is has longer half life

    LPS

  • 73

    Which of these can be used of early diagnosis of Pancreatitis

    AMS

  • 74

    Inhibitors of Trypsin

    A1 ANTITRYPSIN, A2 MACROGLOBULIN

  • 75

    Activator or TRYP

    ENTEROKINASE

  • 76

    This enzyme acts as digestive and cascade initiator

    TRYP

  • 77

    Elevated in acute pancreatitis, chronic renal failure, and cystic fibrosis

    TRYPSIN 1

  • 78

    Rises more significantly in acute pancreatitis especially in urine for about 10x

    TRYPSIN 2

  • 79

    Which of these is a negatively charged

    TRYPSIN 2

  • 80

    Immunochromatographic method using monoclonal antibodies which can used for early detection of pancreatitis marker

    URINARY TRYP 2 TEST STRIP

  • 81

    ELISA based kit or chemiluminescence that detects anti tryp complexes

    IMMUNOASSAY

  • 82

    Elevated tryp+amylase+lipase=

    ACUTE PANCREATITIS

  • 83

    TRYP2>TRYP1 suggest

    ALCOHOL RELATED PANCREATITIS

  • 84

    TRYP1>TRYP2 suggest

    BILIARY ORIGIN

  • 85

    Best for cause classification of pancreatitis

    TRYP

  • 86

    Best for early diagnosis of pancreatitis

    AMY

  • 87

    Best for late pancreatitis detection

    LPS