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Semisold Preparations Part 1
100問 • 4ヶ月前
  • HERSHEY VALERIE BERNARDINO
    • 通報

    問題一覧

  • 1

    Products / dosage forms applied to the skin to treat pathological condition and protects it from other harmful environment.

    semi-solid

  • 2

    Dosage forms that are smooth, non-staining, and get miscible with skin secretions.

    semi-solid

  • 3

    Semi-solid dosage forms are for ___ only

    external use

  • 4

    One of the advantages of semi-solid dosage forms are ____ side effects

    reduced

  • 5

    One of the advantages of semi-solid dosage forms

    it will not undergo first pass effect

  • 6

    One of the advantages of semi-solid dosage forms is that it provides ____ on the affected area

    local action

  • 7

    Advantages of this dosage form is its convenience for unconscious patient or patient who have difficulty in oral administration

    semi-solid

  • 8

    One disadvantage of semi-solid dosage forms is that the bases used in the formulation can be easily ____

    oxidized

  • 9

    One disadvantage of semi-solid dossge forms is its ___

    dosage accuracy

  • 10

    One disadvantage of semi-solid dosage forms

    bulky to handle

  • 11

    Semi-solid dosage forms may sometimes cause irritation or allergy to some patients

    true

  • 12

    Application of semi-solid dosage forms with the use of finger can easily cause ___

    contamination

  • 13

    A dermatological product designed to deliver the drug into the skin in treating dermal disorders.

    topical

  • 14

    Product designed to deliver drugs through the skin (percutaneous absorption) to the general circulation for systemic effects, with the skin not being the target organ.

    transdermal

  • 15

    Semisolid preparations intended for external application of such consistency that they may be readily applied to the skin with or without inunction (rubbing)

    ointments

  • 16

    Uses of ointments (choose 3)

    emollient, protective barrier, vehicle

  • 17

    Type of ointment with medicaments for the treatment of cutaneous infections.

    medicated

  • 18

    Sulfur ointment

    medicated

  • 19

    Zinc oxide ointment

    medicated

  • 20

    Whitfield ointment

    medicated

  • 21

    Compound Resorcinol ointment

    medicated

  • 22

    Sulfur ointment, Zinc oxide ointment, Whitfield ointment, and Compound Resorcinol ointment are examples of

    medicated ointments

  • 23

    Type of ointment also referred to as "ointment bases"

    non-medicated

  • 24

    Type of ointment used as protectants, emollients or lubricants or vehicle (to incorporate in medication)

    non-medicated

  • 25

    Non-medicated ointments are also known as ____ _____ (plural, small letters)

    ointment bases

  • 26

    Non-medicated ointments are used as (choose 3)

    protectants, lubricants, emollients

  • 27

    Water-free and contain petrolatum and/or modified petroleum waxes or paraffin oil

    hydrocarbon / oleaginous bases

  • 28

    Retained on the skin for prolonged period

    hydrocarbon or oleaginous bases

  • 29

    Hydrocarbon bases is also known as ____ bases

    oleaginous

  • 30

    Do not permit the escape of moisture from the skin

    hydrocarbon or oleaginous bases

  • 31

    Difficult to wash-off (greasy)

    hydrocarbon or oleaginous bases

  • 32

    Used for emollient and occlusive action

    hydrocarbon or oleaginous bases

  • 33

    Yellow Petrolatum, Petroleum Jelly, and Vaseline®

    Petrolatum USP

  • 34

    White Petroleum Jelly & White Vaseline®

    White Petrolatum

  • 35

    Simple Ointment which contains 5% yellow wax

    Yellow Ointment

  • 36

    Liquid Petrolatum

    Mineral Oil

  • 37

    Example of hydrocarbon base aside from petrolatum USP, white petrolatum, yellow ointment, and mineral oil (small letters ___ ___)

    white ointment

  • 38

    Not easily removed from the skin with water washing

    absorption bases

  • 39

    Useful as pharmaceutical adjuncts to incorporate small volumes of aqueous solutions into hydrocarbon bases

    absorption bases

  • 40

    Example of absorption bases that permit the incorporation of aqueous solutions, resulting in the formation of water-in-oil emulsions (choose 2)

    Hydrophilic Petrolatum USP, Aquaphor® / Aquabase®

  • 41

    Example of absorption base that are already W/O emulsions that permit the incorporation of small additional quantities of aqueous solutions (choose 1)

    Lanolin, USP (Wool fat)

  • 42

    Lanolin, USP (Wool fat) contains not more than ___ water

    0.25%

  • 43

    Are Oil-in-Water emulsion resembling creams in appearance

    water-removable bases

  • 44

    Are easily washed from the skin

    water-removable bases

  • 45

    Water-removable bases are often called ___ bases (small letters)

    water-washable

  • 46

    May be diluted with water or with aqueous solutions

    water-removable bases

  • 47

    They have the ability to absorb serous discharges

    water-removable bases

  • 48

    Hydrophilic Ointment, USP is an example of

    water-removable bases

  • 49

    Water-soluble bases are commonly referred to as ____ ointment bases

    greaseless

  • 50

    Water-washable because of the absence of oleaginous material

    water-soluble bases

  • 51

    Soften with the addition of large amount of aqueous solution

    water-soluble bases

  • 52

    Polyethylene Glycol Ointment, NF is an example of

    water-soluble bases

  • 53

    Polyethylene Glycol Ointment, NF contains

    40% - PEG 3350 & 60% - PEG 400

  • 54

    2 methods of preparation for ointments (small letters: ___ & ___)

    incorporation & fusion

  • 55

    Method of preparation for ointments via spatulation with geometric dilution technique

    incorporation

  • 56

    Method of preparation for ointments via trituration using mortar and pestle with levigation

    incorporation

  • 57

    Method of preparation for ointments via pulverization by intervention of a gummy material

    incorporation

  • 58

    Incorporation method in which the pharmacist works on the ointment with a stainless steel spatula having a long, broad blade and periodically removes the accumulation of ointment on the large spatula with a smaller one

    via spatulation with geometric dilution technique

  • 59

    Incorporation method in which the ointment base is placed on one side of the working surface and the powdered components, previously reduced to fine powders and thoroughly blended in a mortar, on the other side

    via spatulation with geometric dilution technique

  • 60

    Incorporation method in which a small portion of the powder is mixed with a portion of the base until uniform

    via spatulation with geometric dilution technique

  • 61

    Incorporation method in which the addition of substance portion by portion is continued until all portions of the powder and base are combined and thoroughly and uniformly blended

    via spatulation with geometric dilution technique

  • 62

    Mixing the solid material in a vehicle in which it is insoluble to make a smooth dispersion like mineral oil for bases in which oils are the external phase or glycerin for bases in which water is the external base

    levigation

  • 63

    In incorporation method of ointment via trituration using mortar and pestle with levigation, the levigating agent should be ___ in volume to the solid material

    equal

  • 64

    Used for levigation which allows both reduction of particle size and dispersion of the substance in the vehicle

    mortar and pestle

  • 65

    Incorporation method for ointment in which the dispersion is incorporated into the ointment base by spatulation or with the mortar and pestle until the product is uniform

    via trituration using mortar and pestle with levigation

  • 66

    Incorporation method for camphor

    incorporation of a gummy material via pulverization by intervention

  • 67

    Incorporation method for ointment in which the material is dissolved in a solvent and spread out on the pill tile

    incorporation of a gummy material via pulverization by intervention

  • 68

    Incorporation method for ointment in which the solvent is allowed to evaporate, leaving a thin film of the material onto which the other ingredient/s are spread, then worked into the ingredients by trituration with spatula

    incorporation of a gummy material via pulverization by intervention

  • 69

    Method of preparation for ointments in which all or some of the components of an ointment are combined by being melted together and cooled with constant stirring until congealed

    fusion

  • 70

    Method of preparation for ointments in which the components not melted are added to the congealing mixture as it is being cooled and stirred

    fusion

  • 71

    Method of preparation for ointments in which the heat-labile substances and any volatile components are added last, when the temperature of the mixture is low enough not to cause decomposition or volatilization of the components

    fusion

  • 72

    Ointments containing components such as beeswax, paraffin, stearyl alcohol, and high molecular weight PEGs are prepared by

    fusion

  • 73

    In fusion method, materials with the ___ melting points are heated to the lowest required temperature to produce melt

    highest

  • 74

    In fusion method, additional materials are added with constant stirring during ___ of the melt until the mixture is congealed

    cooling

  • 75

    Dermatological products should be examined for ___ (choose 2)

    P. aeruginosa, S. aureus

  • 76

    Those intended for rectal, urethral, or vaginal should be tested for ___ (choose 2)

    yeasts, molds

  • 77

    Methylparaben, propylparaben, phenols, benzoic acid, sorbic acid, and quaternary ammonium salts should be checked for its

    microbial content

  • 78

    Compensial requirements for ointments according to its net weight or volume of content

    minimum fill

  • 79

    Ointments should be packed in

    large mouth ointment jars, metal or plastic tubes

  • 80

    Ointments must be stored in a ____ and in cool place

    well-closed container

  • 81

    Ointments should be stored in a well-closed container and in a

    cool place

  • 82

    Viscosity of ointments should be checked in the preparation

    true

  • 83

    Which method uses a diffusion cell to determine the drug release drom the ointment preparation?

    In vitro

  • 84

    Creams are also known as ____ ____ (small letters, plural)

    pharmaceutical creams

  • 85

    Semisolid preparations containing one or more medicinal agents dissolved or dispersed in either a water-in-oil (W/O) emulsion or an oil-in-water (O/W) emulsion or in another type of water-washable base

    creams

  • 86

    Find primarily application in topical skin products and in products used rectally and vaginally

    creams

  • 87

    Easier to spread and remove than ointments

    creams

  • 88

    Preparation method for creams

    fusion

  • 89

    O/W creams

    foundation, shaving, hand, and vanishing creams

  • 90

    W/O creams

    cold and emollient creams

  • 91

    Petrolatum Rose Water Ointment

    cold cream

  • 92

    Preferred by patients

    creams

  • 93

    Less sticky

    creams

  • 94

    Easy to spread and remove

    creams

  • 95

    Treats oozing or wet skin conditions

    cream

  • 96

    Covers large areas of skin

    cream

  • 97

    Best used on dry skin

    ointments

  • 98

    Occlusive; traps moisture and are not well absorbed into the skin

    ointment

  • 99

    Promotes more complete absorption of the active ingredient or medication

    ointment

  • 100

    Keeps the skin moist for longer periods of time

    ointment

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    問題一覧

  • 1

    Products / dosage forms applied to the skin to treat pathological condition and protects it from other harmful environment.

    semi-solid

  • 2

    Dosage forms that are smooth, non-staining, and get miscible with skin secretions.

    semi-solid

  • 3

    Semi-solid dosage forms are for ___ only

    external use

  • 4

    One of the advantages of semi-solid dosage forms are ____ side effects

    reduced

  • 5

    One of the advantages of semi-solid dosage forms

    it will not undergo first pass effect

  • 6

    One of the advantages of semi-solid dosage forms is that it provides ____ on the affected area

    local action

  • 7

    Advantages of this dosage form is its convenience for unconscious patient or patient who have difficulty in oral administration

    semi-solid

  • 8

    One disadvantage of semi-solid dosage forms is that the bases used in the formulation can be easily ____

    oxidized

  • 9

    One disadvantage of semi-solid dossge forms is its ___

    dosage accuracy

  • 10

    One disadvantage of semi-solid dosage forms

    bulky to handle

  • 11

    Semi-solid dosage forms may sometimes cause irritation or allergy to some patients

    true

  • 12

    Application of semi-solid dosage forms with the use of finger can easily cause ___

    contamination

  • 13

    A dermatological product designed to deliver the drug into the skin in treating dermal disorders.

    topical

  • 14

    Product designed to deliver drugs through the skin (percutaneous absorption) to the general circulation for systemic effects, with the skin not being the target organ.

    transdermal

  • 15

    Semisolid preparations intended for external application of such consistency that they may be readily applied to the skin with or without inunction (rubbing)

    ointments

  • 16

    Uses of ointments (choose 3)

    emollient, protective barrier, vehicle

  • 17

    Type of ointment with medicaments for the treatment of cutaneous infections.

    medicated

  • 18

    Sulfur ointment

    medicated

  • 19

    Zinc oxide ointment

    medicated

  • 20

    Whitfield ointment

    medicated

  • 21

    Compound Resorcinol ointment

    medicated

  • 22

    Sulfur ointment, Zinc oxide ointment, Whitfield ointment, and Compound Resorcinol ointment are examples of

    medicated ointments

  • 23

    Type of ointment also referred to as "ointment bases"

    non-medicated

  • 24

    Type of ointment used as protectants, emollients or lubricants or vehicle (to incorporate in medication)

    non-medicated

  • 25

    Non-medicated ointments are also known as ____ _____ (plural, small letters)

    ointment bases

  • 26

    Non-medicated ointments are used as (choose 3)

    protectants, lubricants, emollients

  • 27

    Water-free and contain petrolatum and/or modified petroleum waxes or paraffin oil

    hydrocarbon / oleaginous bases

  • 28

    Retained on the skin for prolonged period

    hydrocarbon or oleaginous bases

  • 29

    Hydrocarbon bases is also known as ____ bases

    oleaginous

  • 30

    Do not permit the escape of moisture from the skin

    hydrocarbon or oleaginous bases

  • 31

    Difficult to wash-off (greasy)

    hydrocarbon or oleaginous bases

  • 32

    Used for emollient and occlusive action

    hydrocarbon or oleaginous bases

  • 33

    Yellow Petrolatum, Petroleum Jelly, and Vaseline®

    Petrolatum USP

  • 34

    White Petroleum Jelly & White Vaseline®

    White Petrolatum

  • 35

    Simple Ointment which contains 5% yellow wax

    Yellow Ointment

  • 36

    Liquid Petrolatum

    Mineral Oil

  • 37

    Example of hydrocarbon base aside from petrolatum USP, white petrolatum, yellow ointment, and mineral oil (small letters ___ ___)

    white ointment

  • 38

    Not easily removed from the skin with water washing

    absorption bases

  • 39

    Useful as pharmaceutical adjuncts to incorporate small volumes of aqueous solutions into hydrocarbon bases

    absorption bases

  • 40

    Example of absorption bases that permit the incorporation of aqueous solutions, resulting in the formation of water-in-oil emulsions (choose 2)

    Hydrophilic Petrolatum USP, Aquaphor® / Aquabase®

  • 41

    Example of absorption base that are already W/O emulsions that permit the incorporation of small additional quantities of aqueous solutions (choose 1)

    Lanolin, USP (Wool fat)

  • 42

    Lanolin, USP (Wool fat) contains not more than ___ water

    0.25%

  • 43

    Are Oil-in-Water emulsion resembling creams in appearance

    water-removable bases

  • 44

    Are easily washed from the skin

    water-removable bases

  • 45

    Water-removable bases are often called ___ bases (small letters)

    water-washable

  • 46

    May be diluted with water or with aqueous solutions

    water-removable bases

  • 47

    They have the ability to absorb serous discharges

    water-removable bases

  • 48

    Hydrophilic Ointment, USP is an example of

    water-removable bases

  • 49

    Water-soluble bases are commonly referred to as ____ ointment bases

    greaseless

  • 50

    Water-washable because of the absence of oleaginous material

    water-soluble bases

  • 51

    Soften with the addition of large amount of aqueous solution

    water-soluble bases

  • 52

    Polyethylene Glycol Ointment, NF is an example of

    water-soluble bases

  • 53

    Polyethylene Glycol Ointment, NF contains

    40% - PEG 3350 & 60% - PEG 400

  • 54

    2 methods of preparation for ointments (small letters: ___ & ___)

    incorporation & fusion

  • 55

    Method of preparation for ointments via spatulation with geometric dilution technique

    incorporation

  • 56

    Method of preparation for ointments via trituration using mortar and pestle with levigation

    incorporation

  • 57

    Method of preparation for ointments via pulverization by intervention of a gummy material

    incorporation

  • 58

    Incorporation method in which the pharmacist works on the ointment with a stainless steel spatula having a long, broad blade and periodically removes the accumulation of ointment on the large spatula with a smaller one

    via spatulation with geometric dilution technique

  • 59

    Incorporation method in which the ointment base is placed on one side of the working surface and the powdered components, previously reduced to fine powders and thoroughly blended in a mortar, on the other side

    via spatulation with geometric dilution technique

  • 60

    Incorporation method in which a small portion of the powder is mixed with a portion of the base until uniform

    via spatulation with geometric dilution technique

  • 61

    Incorporation method in which the addition of substance portion by portion is continued until all portions of the powder and base are combined and thoroughly and uniformly blended

    via spatulation with geometric dilution technique

  • 62

    Mixing the solid material in a vehicle in which it is insoluble to make a smooth dispersion like mineral oil for bases in which oils are the external phase or glycerin for bases in which water is the external base

    levigation

  • 63

    In incorporation method of ointment via trituration using mortar and pestle with levigation, the levigating agent should be ___ in volume to the solid material

    equal

  • 64

    Used for levigation which allows both reduction of particle size and dispersion of the substance in the vehicle

    mortar and pestle

  • 65

    Incorporation method for ointment in which the dispersion is incorporated into the ointment base by spatulation or with the mortar and pestle until the product is uniform

    via trituration using mortar and pestle with levigation

  • 66

    Incorporation method for camphor

    incorporation of a gummy material via pulverization by intervention

  • 67

    Incorporation method for ointment in which the material is dissolved in a solvent and spread out on the pill tile

    incorporation of a gummy material via pulverization by intervention

  • 68

    Incorporation method for ointment in which the solvent is allowed to evaporate, leaving a thin film of the material onto which the other ingredient/s are spread, then worked into the ingredients by trituration with spatula

    incorporation of a gummy material via pulverization by intervention

  • 69

    Method of preparation for ointments in which all or some of the components of an ointment are combined by being melted together and cooled with constant stirring until congealed

    fusion

  • 70

    Method of preparation for ointments in which the components not melted are added to the congealing mixture as it is being cooled and stirred

    fusion

  • 71

    Method of preparation for ointments in which the heat-labile substances and any volatile components are added last, when the temperature of the mixture is low enough not to cause decomposition or volatilization of the components

    fusion

  • 72

    Ointments containing components such as beeswax, paraffin, stearyl alcohol, and high molecular weight PEGs are prepared by

    fusion

  • 73

    In fusion method, materials with the ___ melting points are heated to the lowest required temperature to produce melt

    highest

  • 74

    In fusion method, additional materials are added with constant stirring during ___ of the melt until the mixture is congealed

    cooling

  • 75

    Dermatological products should be examined for ___ (choose 2)

    P. aeruginosa, S. aureus

  • 76

    Those intended for rectal, urethral, or vaginal should be tested for ___ (choose 2)

    yeasts, molds

  • 77

    Methylparaben, propylparaben, phenols, benzoic acid, sorbic acid, and quaternary ammonium salts should be checked for its

    microbial content

  • 78

    Compensial requirements for ointments according to its net weight or volume of content

    minimum fill

  • 79

    Ointments should be packed in

    large mouth ointment jars, metal or plastic tubes

  • 80

    Ointments must be stored in a ____ and in cool place

    well-closed container

  • 81

    Ointments should be stored in a well-closed container and in a

    cool place

  • 82

    Viscosity of ointments should be checked in the preparation

    true

  • 83

    Which method uses a diffusion cell to determine the drug release drom the ointment preparation?

    In vitro

  • 84

    Creams are also known as ____ ____ (small letters, plural)

    pharmaceutical creams

  • 85

    Semisolid preparations containing one or more medicinal agents dissolved or dispersed in either a water-in-oil (W/O) emulsion or an oil-in-water (O/W) emulsion or in another type of water-washable base

    creams

  • 86

    Find primarily application in topical skin products and in products used rectally and vaginally

    creams

  • 87

    Easier to spread and remove than ointments

    creams

  • 88

    Preparation method for creams

    fusion

  • 89

    O/W creams

    foundation, shaving, hand, and vanishing creams

  • 90

    W/O creams

    cold and emollient creams

  • 91

    Petrolatum Rose Water Ointment

    cold cream

  • 92

    Preferred by patients

    creams

  • 93

    Less sticky

    creams

  • 94

    Easy to spread and remove

    creams

  • 95

    Treats oozing or wet skin conditions

    cream

  • 96

    Covers large areas of skin

    cream

  • 97

    Best used on dry skin

    ointments

  • 98

    Occlusive; traps moisture and are not well absorbed into the skin

    ointment

  • 99

    Promotes more complete absorption of the active ingredient or medication

    ointment

  • 100

    Keeps the skin moist for longer periods of time

    ointment