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Hematopoiesis
44問 • 1年前
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  • 通報

    問題一覧

  • 1

    What are the cells located in the circulation?

    Reticulocyte, Erythrocyte

  • 2

    What is the life span of an Erythrocyte?

    ~120 days unless aged or damaged

  • 3

    How long does the process of a Reticulocyte turning into a Erythrocyte take?

    24-48hrs

  • 4

    Stages of Erythropoiesis in the bone marrow

    Stem Cell, Prorubroblast, Early Erythrocyte, Late Erythrocyte, Normablast

  • 5

    At what stage does Hemoglobin accumulation occur?

    in the late Erythroblast stage hemoglobin starts to accumulate

  • 6

    At what stage does Ribosome Synthesis occur?

    In the Early Erythroblast stage, ribosome synthesis occurs

  • 7

    How long to Reticulocytes stay in the bone marrow for before transferring to the circulation?

    ~3 days

  • 8

    Where can you find Macrophages?

    Spleen, Bone, Liver

  • 9

    What do old Erythrocytes break into after being viciously eaten by a macrophage?

    Globin(Amino Acids), Heme(Bilirubin, Iron)

  • 10

    What do macrophages do?

    Eats old Erythrocytes, Breaks down Old Erythrocytes

  • 11

    What are mature red blood cells responsible for?

    Transporting Oxygen around our body

  • 12

    What are some causes of Myeloid Dysplastice Disorder?

    Infections, Bone Marrow Dysplasia, Immune-Mediated neutropenia(due to steroids), Drug Toxicity

  • 13

    What is primary Myeloid Dysplastic Disorder?

    Primary means that it is Congenital (Disease/abnormality present from birth)

  • 14

    What do you use the 10x microscope objective for?

    To observe the entire slide and cell distrobution

  • 15

    What is a myloid Dysplastic Disorder?

    Abnormal Developement of hematopoietic stem cells

  • 16

    What do you use a 100x microscope objective for?

    to observe RBC’s + WBC’s for cellular content (Granules, Vacuoles, Parasites, etc)

  • 17

    What do you use the 40x microscope objective for?

    Perform a differential

  • 18

    What is the Feline PCV Reference range?

    30-45%

  • 19

    What is the canine reference range for PCV

    37-55%

  • 20

    What is PCV?

    Packed Cell Volume

  • 21

    What happens when hgb is released?

    hgb is transported to the lover and broken down by a macrophage, Iron and Amino acids are recycled

  • 22

    How are hgb contents recycled after escaping an old or damaged red blood cell?

    Amino acid is directly transported back into circulation and travels to the bone marrow from there to be re-used in erythropoiesis, Iron and Bilirubin both go to the liver. Iron is then brought back into circulation by transferrin and travels back into the bone marrow. Bilirubin is excreted through the bile system through the bile duct.

  • 23

    Nutrients that is used in Erythropoiesis

    Amino Acids, Monosaccharides, Lipids, Vitamin B12, Folic Acid, Iron

  • 24

    What are reticulocytes stained purple?

    The hemoglobin is purple in colour due to retained reticulum

  • 25

    What are the forms of Hemoglobin?

    Oxyhemoglobin, Carboxyhemoglobin

  • 26

    What is Oxyhemoglobin?

    hgb bound to oxygen

  • 27

    What are carboxyhemoglobins

    hgb bound to carbon monoxide, cannot escape the clutches of the carbon monoxide

  • 28

    What re the purpose(s) of hemoglobin

    carry oxygen to cells and exchange it for carbon dioxide., aids in PH regulation

  • 29

    What does the word ‘hemoglobin’ mean?

    Heme(Iron)globin(Protein)

  • 30

    What is the feline hgb reference range?

    8-15g/dl

  • 31

    What is the canine reference range for hemoglobin?

    12-18g/dl

  • 32

    What causes hypochromasia?

    A lack of Hemoglobin

  • 33

    What are the stages of Granulopoiesis?

    Heamocytoblast, Myeloid Stem Cell, Myeloblast, Promyelocyte, Mylocyte, Metamylocyte, Band Form, Granulocyte.

  • 34

    What kind of Erythrocyteid Nucleated?

    Avian RBC, Reptile RBC

  • 35

    Description of an erythrocyte

    Ranges from 3-7um, stains pink in colour with an area of central pallor

  • 36

    What are the stages of Erythropoiesis in order?

    Stem cell, Rubroblast, Prorubrocyte, Rubrocyte, Metarubrocyte, Reticulocyte, Erythrocyte

  • 37

    Locations of hematopoiesis in the very young

    Red bone marrow, Liver, Speen, Thymus

  • 38

    What do Megakaryocytes do?

    Produce Platelets

  • 39

    Locations of hematopoiesis in adults in distress

    Red bone marrow, Yellow bone marrow converts into red bone marrow, Liver, Spleen

  • 40

    Location of hematopoiesis in adults

    Red bone marrow

  • 41

    What do RBC’s require to make hemoglobin?

    Iron, B6, B12, Folate, Amino Acid, Trace Metals

  • 42

    When is hgb released from RBC’S?

    when RBC’S lyse

  • 43

    What is a Hematocrit (HCT)?

    PCV

  • 44

    What is HCT?

    Hematocrit

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    問題一覧

  • 1

    What are the cells located in the circulation?

    Reticulocyte, Erythrocyte

  • 2

    What is the life span of an Erythrocyte?

    ~120 days unless aged or damaged

  • 3

    How long does the process of a Reticulocyte turning into a Erythrocyte take?

    24-48hrs

  • 4

    Stages of Erythropoiesis in the bone marrow

    Stem Cell, Prorubroblast, Early Erythrocyte, Late Erythrocyte, Normablast

  • 5

    At what stage does Hemoglobin accumulation occur?

    in the late Erythroblast stage hemoglobin starts to accumulate

  • 6

    At what stage does Ribosome Synthesis occur?

    In the Early Erythroblast stage, ribosome synthesis occurs

  • 7

    How long to Reticulocytes stay in the bone marrow for before transferring to the circulation?

    ~3 days

  • 8

    Where can you find Macrophages?

    Spleen, Bone, Liver

  • 9

    What do old Erythrocytes break into after being viciously eaten by a macrophage?

    Globin(Amino Acids), Heme(Bilirubin, Iron)

  • 10

    What do macrophages do?

    Eats old Erythrocytes, Breaks down Old Erythrocytes

  • 11

    What are mature red blood cells responsible for?

    Transporting Oxygen around our body

  • 12

    What are some causes of Myeloid Dysplastice Disorder?

    Infections, Bone Marrow Dysplasia, Immune-Mediated neutropenia(due to steroids), Drug Toxicity

  • 13

    What is primary Myeloid Dysplastic Disorder?

    Primary means that it is Congenital (Disease/abnormality present from birth)

  • 14

    What do you use the 10x microscope objective for?

    To observe the entire slide and cell distrobution

  • 15

    What is a myloid Dysplastic Disorder?

    Abnormal Developement of hematopoietic stem cells

  • 16

    What do you use a 100x microscope objective for?

    to observe RBC’s + WBC’s for cellular content (Granules, Vacuoles, Parasites, etc)

  • 17

    What do you use the 40x microscope objective for?

    Perform a differential

  • 18

    What is the Feline PCV Reference range?

    30-45%

  • 19

    What is the canine reference range for PCV

    37-55%

  • 20

    What is PCV?

    Packed Cell Volume

  • 21

    What happens when hgb is released?

    hgb is transported to the lover and broken down by a macrophage, Iron and Amino acids are recycled

  • 22

    How are hgb contents recycled after escaping an old or damaged red blood cell?

    Amino acid is directly transported back into circulation and travels to the bone marrow from there to be re-used in erythropoiesis, Iron and Bilirubin both go to the liver. Iron is then brought back into circulation by transferrin and travels back into the bone marrow. Bilirubin is excreted through the bile system through the bile duct.

  • 23

    Nutrients that is used in Erythropoiesis

    Amino Acids, Monosaccharides, Lipids, Vitamin B12, Folic Acid, Iron

  • 24

    What are reticulocytes stained purple?

    The hemoglobin is purple in colour due to retained reticulum

  • 25

    What are the forms of Hemoglobin?

    Oxyhemoglobin, Carboxyhemoglobin

  • 26

    What is Oxyhemoglobin?

    hgb bound to oxygen

  • 27

    What are carboxyhemoglobins

    hgb bound to carbon monoxide, cannot escape the clutches of the carbon monoxide

  • 28

    What re the purpose(s) of hemoglobin

    carry oxygen to cells and exchange it for carbon dioxide., aids in PH regulation

  • 29

    What does the word ‘hemoglobin’ mean?

    Heme(Iron)globin(Protein)

  • 30

    What is the feline hgb reference range?

    8-15g/dl

  • 31

    What is the canine reference range for hemoglobin?

    12-18g/dl

  • 32

    What causes hypochromasia?

    A lack of Hemoglobin

  • 33

    What are the stages of Granulopoiesis?

    Heamocytoblast, Myeloid Stem Cell, Myeloblast, Promyelocyte, Mylocyte, Metamylocyte, Band Form, Granulocyte.

  • 34

    What kind of Erythrocyteid Nucleated?

    Avian RBC, Reptile RBC

  • 35

    Description of an erythrocyte

    Ranges from 3-7um, stains pink in colour with an area of central pallor

  • 36

    What are the stages of Erythropoiesis in order?

    Stem cell, Rubroblast, Prorubrocyte, Rubrocyte, Metarubrocyte, Reticulocyte, Erythrocyte

  • 37

    Locations of hematopoiesis in the very young

    Red bone marrow, Liver, Speen, Thymus

  • 38

    What do Megakaryocytes do?

    Produce Platelets

  • 39

    Locations of hematopoiesis in adults in distress

    Red bone marrow, Yellow bone marrow converts into red bone marrow, Liver, Spleen

  • 40

    Location of hematopoiesis in adults

    Red bone marrow

  • 41

    What do RBC’s require to make hemoglobin?

    Iron, B6, B12, Folate, Amino Acid, Trace Metals

  • 42

    When is hgb released from RBC’S?

    when RBC’S lyse

  • 43

    What is a Hematocrit (HCT)?

    PCV

  • 44

    What is HCT?

    Hematocrit