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Pharm Induction Agents

Pharm Induction Agents
58問 • 2024-01-30
  • Julia Skellie
    • 通報

    Antagonist

    Antagonist

    Julia Skellie · 178問 · 2年前

    Antagonist

    Antagonist

    178問 • 2年前
    Julia Skellie

    Monitors

    Monitors

    Julia Skellie · 144問 · 2年前

    Monitors

    Monitors

    144問 • 2年前
    Julia Skellie

    Positioning

    Positioning

    Julia Skellie · 88問 · 2年前

    Positioning

    Positioning

    88問 • 2年前
    Julia Skellie

    arterial vasodilators, peripheral vasodilators, CCB

    arterial vasodilators, peripheral vasodilators, CCB

    Julia Skellie · 122問 · 2年前

    arterial vasodilators, peripheral vasodilators, CCB

    arterial vasodilators, peripheral vasodilators, CCB

    122問 • 2年前
    Julia Skellie

    AntiArrhythmics

    AntiArrhythmics

    Julia Skellie · 70問 · 2年前

    AntiArrhythmics

    AntiArrhythmics

    70問 • 2年前
    Julia Skellie

    just dont forget:

    just dont forget:

    Julia Skellie · 8問 · 2年前

    just dont forget:

    just dont forget:

    8問 • 2年前
    Julia Skellie

    Rspiratory

    Rspiratory

    Julia Skellie · 42問 · 2年前

    Rspiratory

    Rspiratory

    42問 • 2年前
    Julia Skellie

    Monitored and Conscious Sedation

    Monitored and Conscious Sedation

    Julia Skellie · 48問 · 2年前

    Monitored and Conscious Sedation

    Monitored and Conscious Sedation

    48問 • 2年前
    Julia Skellie

    Emergence

    Emergence

    Julia Skellie · 29問 · 2年前

    Emergence

    Emergence

    29問 • 2年前
    Julia Skellie

    PACU

    PACU

    Julia Skellie · 14問 · 2年前

    PACU

    PACU

    14問 • 2年前
    Julia Skellie

    Random

    Random

    Julia Skellie · 19問 · 2年前

    Random

    Random

    19問 • 2年前
    Julia Skellie

    pharm exam 3

    pharm exam 3

    Julia Skellie · 42問 · 2年前

    pharm exam 3

    pharm exam 3

    42問 • 2年前
    Julia Skellie

    Laparoscopic Surgery

    Laparoscopic Surgery

    Julia Skellie · 39問 · 2年前

    Laparoscopic Surgery

    Laparoscopic Surgery

    39問 • 2年前
    Julia Skellie

    Hematology Coagulation

    Hematology Coagulation

    Julia Skellie · 66問 · 2年前

    Hematology Coagulation

    Hematology Coagulation

    66問 • 2年前
    Julia Skellie

    LIVER

    LIVER

    Julia Skellie · 84問 · 2年前

    LIVER

    LIVER

    84問 • 2年前
    Julia Skellie

    ENT

    ENT

    Julia Skellie · 17問 · 2年前

    ENT

    ENT

    17問 • 2年前
    Julia Skellie

    Opioids

    Opioids

    Julia Skellie · 18問 · 2年前

    Opioids

    Opioids

    18問 • 2年前
    Julia Skellie

    MH

    MH

    Julia Skellie · 32問 · 2年前

    MH

    MH

    32問 • 2年前
    Julia Skellie

    NeuroSurg

    NeuroSurg

    Julia Skellie · 20問 · 2年前

    NeuroSurg

    NeuroSurg

    20問 • 2年前
    Julia Skellie

    Burns

    Burns

    Julia Skellie · 89問 · 2年前

    Burns

    Burns

    89問 • 2年前
    Julia Skellie

    Regional

    Regional

    Julia Skellie · 11問 · 2年前

    Regional

    Regional

    11問 • 2年前
    Julia Skellie

    問題一覧

  • 1

    Isopropylphenol:

    propofol

  • 2

    pain on injection:

    propofol, etomidate

  • 3

    Extraheptic clearance:

    propofol

  • 4

    anti-epileptic properties and generally not used in ECT:

    propofol

  • 5

    hallucinations, sexual fantasies, euphoria:

    propofol

  • 6

    moderate bronchodilation:

    propofol

  • 7

    subhypnotic dose of 10mg as antiemetic:

    propofol

  • 8

    anaphylactic reactions have been reported:

    propofol

  • 9

    high abuse potential:

    propofol

  • 10

    carboxylated imidazole:

    etomidate

  • 11

    emulsified in propylene glycol

    etomidate

  • 12

    hypnotic with no analgesia

    etomidate

  • 13

    2 isomer: only positive isomer is R isomer

    etomidate

  • 14

    provides most hemodynamic stability

    etomidate

  • 15

    rapid metabolism in liver by ester hydrolysis

    etomidate

  • 16

    adrenocorticoid suppression

    etomidate

  • 17

    best for ECT:

    etomidate

  • 18

    associated with PONV

    etomidate

  • 19

    involuntary myoclonus

    etomidate

  • 20

    can cause hiccups

    etomidate

  • 21

    no effect to sympathetic nervous system or baroreceptor

    etomidate

  • 22

    contraindicated with porphyria

    thiopental, etomidate

  • 23

    phencyclidine

    ketamine

  • 24

    racemic mixture: both R and S isomer

    ketamine

  • 25

    metabolism in liver via NP450

    ketamine

  • 26

    active metabolite:

    ketamine

  • 27

    lowest protein binding

    ketamine

  • 28

    potent cerebral vasodilation

    ketamine

  • 29

    direct myocardial depressant but masked by SNS activity

    ketamine

  • 30

    increase salivary and tracheobronchial gland secretions

    ketamine, thiopental

  • 31

    inhibit platelet aggregation

    ketamine

  • 32

    enhances nondepolarizing NMB

    ketamine

  • 33

    barbiturate:

    thiopental

  • 34

    powder, sodium salt and requires reconstitution

    thiopental

  • 35

    caution if injected arterialy:

    thiopental

  • 36

    hepatic metabolism via oxidation and N-dealkylation

    thiopental

  • 37

    chronic administration associated with induction of microsomal enzymes

    thiopental

  • 38

    highest context sensitive half life

    thiopental

  • 39

    best for neuro patients

    thiopental

  • 40

    decrease BP and increase HR

    thiopental

  • 41

    propofol dose: induction: conscious sedation gtt: maintenance gtt:

    induction: 1-3 mg/kg CS gtt: 25-100 mcg/kg/min M gtt: 100-300 mcg/kg/min

  • 42

    explain propofol allergy considerations:

    allergy to egg and soy is rare emulsion formula made of soybean, glycerol, lecithin

  • 43

    lipids in propofol pose what risk:

    bacterial contamination, use within 6 hours

  • 44

    pharmokinetics of propofol are dependent on: 4 factors

    gender weight age disease

  • 45

    dose change in elderly and children with propofol: and why?

    children: increase dose bc larger central compartment and higher clearance elderly: decrease by 25-50%

  • 46

    termination of propofol via

    redistribution to fat and muscle

  • 47

    propofol obesity induction dose: TBW or LBW

    LBW

  • 48

    propofol peak:

    1 min

  • 49

    propofol elimination half life:

    1-3 hours

  • 50

    propofol cardiac instability exaggerated if: 3 factors

    hypovolemia elderly LV dysfunction

  • 51

    how to treat propofol induced bradycardia

    isoproterenol, bc decreased response to atropine

  • 52

    propofol and baroreceptor activity

    blunts baroreceptor decreases tachy response to hypotension

  • 53

    because propofol inhibits sympathetic vasoconstrictor activity, what should you do prior to sx?

    adequate hydration

  • 54

    4 predictors of cardiac instability:

    age 50 + ASA 3 or 4 MAP under 70 coadmin with high dose of fentanyl

  • 55

    etomidate induction dose:

    0.2-0.3 mg/kg

  • 56

    adverse effects of etomidate:

    myocolus PONV adrenocorticoid suppression contra with porphyria

  • 57

    adrenocorticoid suppression: etomidate what 2 hormones are suppressed for how long? dose dependent inhibition of what enzyme and reaction?

    decrease cortisol and aldosterone suppression for 4-8 hours insufficient for 24-48 hours dose dependent inhibition of 11 B hydroxylase that converts cholesterol to cortisol

  • 58

    what does ketamine provide as an induction agent

    amnesia analgesia dissociative anesthesia nystagmus