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Nephron Dis 1
  • Jef Marc Valencia

  • 問題数 93 • 1/23/2025

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    問題一覧

  • 1

    The nephron is the functional unit of the kidney located mostly in the

    RENAL CORTEX

  • 2

    Each kidney how many nephron contains

    1.2-1.5 MILLION

  • 3

    What are the two types of nephron according to location

    CORTICAL, JUXTAMEDULLARY

  • 4

    Nephrons are located in the cortex but for the loop of henle extends until the

    OUTER RENAL MEDULLA

  • 5

    Blood supply in the cortical nephron is supplied by

    PERITUBULAR ARTERY

  • 6

    Nephron which main function is for remove waste product and reabsorption of nutrients

    CORTICAL

  • 7

    It comprises approximately 85% of the total number of nephron

    CORTICAL

  • 8

    Type of nephron that it have loops of henle that extend into the outer medullary region until the vasarecta

    JUXTAMEDULLARY NEPHRON

  • 9

    Type of nephron that its main function is for urine concentration and countercurrent exchanges

    JUXTAMEDULLARY NEPHRON

  • 10

    What are the two main components of nephron

    RENAL CORPUSCLE, RENAL TUBULE

  • 11

    What are the components of renal corpuscle

    GLOMERULUS, BOWMAN'S CAPSULE, AFFERENT ARTERIOLE, EFFERENT ARTERIOLE

  • 12

    This is the filtering component which is composed of specialized capillary network found at the inside the bowman's capsule

    GLOMERULUS

  • 13

    This is where the filtrate goes after the glomerulus which structure surround the glomerulus and anatomically continuous with the renal tubule

    BOWMAN'S CAPSULE

  • 14

    It has a bigger lumen and carries blood to the glomerulus

    AFFERENT ARTERIOLE

  • 15

    It has a smaller lumen and carries blood from the glomerulus

    EFFERENT ARTERIOLE

  • 16

    Part of the distal convulated tubule that is attached to the afferent arteriole which main function is to detect changes in pressure

    MACULA DENSA

  • 17

    The fluid inside the bowman's space is called

    ULTRAFILTRATE

  • 18

    What are the factors affecting the glomerular filtration

    FILTRATION BARRIER, NET FILTRATION PRESSURE, RENIN ANGIOTENSIN ALDOSTERONE SYSTEM

  • 19

    Filtration barrier is composed of

    FENESTRATED ENDOTHELIUM, BASEMENT MEMBRANE, VISCERAL EPITHELIUM

  • 20

    It is a filtration barrier that increases the permeability due to its pores

    FENESTRATED ENDOTHELIUM, MESANGIUM

  • 21

    It is a smooth muscle in the penetrated endothelium which functions for contraction phagocytosis and pinocytosis

    MESANGIUM

  • 22

    How many nanometers do fenestrated endothelium

    50-100

  • 23

    This is the filtration barrier which provides for the restriction main size discriminant barrier to protein passage

    BASEMENT MEMBRANE

  • 24

    Filtration barrier that separates epithelium of the urinary space from the endothelium of glomerular capillaries

    BASEMENT MEMBRANE

  • 25

    Characterized by intertwining foot processes which forms forms filtration slits

    VISCERAL EPITHELIUM, PODOCYTE

  • 26

    Lines davao man's space which is like a finger like processes

    PODOCYTE

  • 27

    Podocytes are intertwining foot processes with finger like extension which is separated from each other about how many nanometers

    20-30

  • 28

    Afforded by negatively charged components which provides additional restriction by refilling negatively charged molecules like albumin and plasma proteins

    SHIELD OF NEGATIVITY

  • 29

    What are the three forces involved for the net filtration pressure

    GLOMERULAR BLOOD HYDROSTATIC PRESSURE, CAPSULAR HYDROSTATIC PRESSURE, BLOOD COLLOID OSMOTIC PRESSURE

  • 30

    The pressure that forces substances like protein free filtrate from the glomerular capillaries into the bowman's capsule

    NET FILTRATION PRESSURE

  • 31

    This is the capillary blood hydrostatic pressure usually measures about 60 mmhg

    GLOMERULAR BLOOD HYDROSTATIC PRESSURE

  • 32

    This is the pressure in the glomerular capillary forcing water and its solutes through filtration slits

    GLOMERULAR BLOOD HYDROSTATIC PRESSURE

  • 33

    Chp and bchp are also known as

    OPPOSING PRESSURE

  • 34

    This is the pressure exerted against the filtration membrane by fluid that is already in the capsular space

    CAPSULAR HYDROSTATIC PRESSURE

  • 35

    It is a pressure exerted by the proteins in the blood plasma

    BLOOD COLLOID OSMOTIC PRESSURE

  • 36

    The formula in computing the net outward pressure

    GBHP-CHP-BCHP

  • 37

    It directly affects the kidneys functional ability

    RENAL BLOOD FLOW

  • 38

    How many percent of cardiac output goes to the kidneys

    25%

  • 39

    What is the total renal blood flow

    1200 ML/MIN

  • 40

    What is the total renal plasma flow

    600-700 ML/MIN

  • 41

    It is a capillary bed that surround the convulated tubules which function as the vascular supply

    PERITUBULAR CAPILLARY

  • 42

    It is the capillary bed that surrounds the loop of henle which function to receive water and solutes so that it can be turn it back to circulation

    VASA RECTA

  • 43

    It drains blood from the kidneys

    RENAL VEIN

  • 44

    Renal

    u

  • 45

    Rate of filtration in the glomerulus which processes involves the filtration of blood which leads to formation of the ultra filtrate

    GLOMERULAR FILTRATION

  • 46

    It serves as a non-selective filter or sieve of plasma substances with a molecular weight of less than 70,000

    GLOMERULUS

  • 47

    What are the parts of the renal tubules

    PROXIMAL CONVOLUTED TUBULE, LOOP OF HENLE, DISTAL CONVOLUTED TUBULE, COLLECTING DUCT

  • 48

    It is the most convulated tubule which is the straight portion which becomes the loop of henle once it reaches the medulla

    PROXIMAL CONVOLUTED TUBULE

  • 49

    Renal tubule composed of thin descending segment u shape segment and thick and thin ascending segment

    LOOP OF HENLE

  • 50

    Renal tubule composed of 2-3 loops only that begins at the juxtaglomerular apparatus with the macula densa

    DISTAL CONVOLUTED TUBULE

  • 51

    This tubule tra versus the renal cortex and medola which serves as the site of final urine concentration

    COLLECTING DUCT

  • 52

    What is the epithelium of proximal convoluted tubule

    INTERDIGITATING WITH MICROVILLI

  • 53

    This is the part of brush border epithelium of proximal convulated tubule which functions for reabsorption of nutrients

    MICROVILLI

  • 54

    It is a part of the renal tubule which is responsible for 60% of nutrient reabsorption

    PROXIMAL CONVOLUTED TUBULE

  • 55

    Is the characteristics of finger like appearance of epithelium

    INTERDIGITATING EPITHELIUM

  • 56

    The first segment of the loop of henle

    THIN DESCENDING SEGMENT

  • 57

    Thin descending segment is made up of what cell and epithelium

    NON INTERDIGITATING, FLAT

  • 58

    It is also known as u shaped segment which is a part of loop of henle made up of flat cells and extensively interdigitating epithelium

    HAIRPIN

  • 59

    What cells made up thin ascending loop of henle

    FLAT

  • 60

    What cell and epithelium made up the thick ascending loop of henle

    TALL, INTERDIGITATING EPITHELIUM

  • 61

    It is a segment of loop of henle with high mitochondrial and enzymatic activity in the 2/3 of the distal basal layer

    THICK ASCENDING SEGMENT

  • 62

    What segment of loop of henley is permeable to water

    THIN ASCENDING SEGMENT

  • 63

    Segment of loop of henle which is in permeable to water which is permeable to sodium chloride

    THIN DESCENDING SEGMENT

  • 64

    It regulates the blood flow and within the glomerulus

    RENIN ANGIOTENSIN ALDOSTERONE SYSTEM

  • 65

    What part of the raas system which the distal convoluted tubule and efferent arteriole meets

    JUXTAGLOMERULAR APPARATUS

  • 66

    It responds to changes in blood pressure and plasma sodium concentration

    RENIN ANGIOTENSIN ALDOSTERONE SYSTEM

  • 67

    What is the triggering mechanism of the RAAS

    LOW PLASMA SODIUM CONCENTRATION, LOW BLOOD PRESSURE

  • 68

    It is also known as the sodium retaining hormone which is secreted by adrenal cortex

    ALDOSTERONE

  • 69

    This hormone increases the water reabsorption

    VASOPRESSIN

  • 70

    Angiotensin

    phyo

  • 71

    What hormone increases the sodium reabsorption in the dct

    ALDOSTERONE

  • 72

    How many percent of ultrafiltrate is excreted in the urine

    1%

  • 73

    This is the movement of molecules from the tubular capillaries to the tubular lumen

    TUBULAR REABSORPTION

  • 74

    The movement of substances from capillaries and instertitial to the tubular lumen

    TUBULAR SECRETION

  • 75

    Reabsorption is made possible by the what structure

    MICROVILLI

  • 76

    The maximum limit of renal tubules can reabsorbs certain substances

    RENAL THRESHOLD

  • 77

    These are the two mechanisms that is needed for tubular reabsorption and renal threshold

    ACTIVE TRANSPORT, PASSIVE TRANSPORT

  • 78

    It is a type of active transport which needs carrier protein to pass through

    INDIRECT TRANSPORT

  • 79

    It is an active transport that needs ATP or energy to pass through

    DIRECT TRANSPORT

  • 80

    Movement of molecules across a membrane by diffusion becauseof a physical gradient which doesn't need energy as concentration is from high to low level

    PASSIVE TRANSPORT

  • 81

    This is a reabsorption mechanism which transfer of substances is brought about by the electrochemical energy and substance must combine with a carrier protein or an energy

    ACTIVE TRANSPORT

  • 82

    Movement of substances from the blood in renal capillary beds to the filtrate in the tubular lumen

    TUBULAR SECRETION

  • 83

    What are the two major function of tubular secretion

    ELIMINATION OF WASTE PRODUCT, REGULATION OF ACID AND BASE

  • 84

    The normal blood ph

    7.35-7.45

  • 85

    This is when after eating and urine is collected acidic caused by the production of carbon dioxide from the oxidative metabolism of food and catabolism of proteins and phosphate

    ALKALINE TIDE

  • 86

    What are the three mechanisms for acid base balance of the body

    BLOOD BUFFER, PULMONARY, RENAL SYSTEM

  • 87

    Monosodium phosphate that was excreted in the urine

    TITRABLE ACID

  • 88

    Titrable acid has the ability to titrate urine into what ph

    7.4

  • 89

    Hormone that Responds to the body's need for Na and promotes Na reabsorption in the DCT

    ALDOSTERONE

  • 90

    Responds to the body's need for water and promotes water reabsorption in the DCT and CD

    VASOPRESSIN

  • 91

    Countercurrent Mechanism in DLH

    WATER REABSORPTION

  • 92

    Countercurrent Mechanism in ALH

    SODIUM AND CHLORIDE REABSORPTION

  • 93

    Essential substances are returned to the circulation. Substances are transported from the flitrate back to the blood

    TUBULAR REABSORPTION