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1
The nephron is the functional unit of the kidney located mostly in the
RENAL CORTEX
2
Each kidney how many nephron contains
1.2-1.5 MILLION
3
What are the two types of nephron according to location
CORTICAL, JUXTAMEDULLARY
4
Nephrons are located in the cortex but for the loop of henle extends until the
OUTER RENAL MEDULLA
5
Blood supply in the cortical nephron is supplied by
PERITUBULAR ARTERY
6
Nephron which main function is for remove waste product and reabsorption of nutrients
CORTICAL
7
It comprises approximately 85% of the total number of nephron
CORTICAL
8
Type of nephron that it have loops of henle that extend into the outer medullary region until the vasarecta
JUXTAMEDULLARY NEPHRON
9
Type of nephron that its main function is for urine concentration and countercurrent exchanges
JUXTAMEDULLARY NEPHRON
10
What are the two main components of nephron
RENAL CORPUSCLE, RENAL TUBULE
11
What are the components of renal corpuscle
GLOMERULUS, BOWMAN'S CAPSULE, AFFERENT ARTERIOLE, EFFERENT ARTERIOLE
12
This is the filtering component which is composed of specialized capillary network found at the inside the bowman's capsule
GLOMERULUS
13
This is where the filtrate goes after the glomerulus which structure surround the glomerulus and anatomically continuous with the renal tubule
BOWMAN'S CAPSULE
14
It has a bigger lumen and carries blood to the glomerulus
AFFERENT ARTERIOLE
15
It has a smaller lumen and carries blood from the glomerulus
EFFERENT ARTERIOLE
16
Part of the distal convulated tubule that is attached to the afferent arteriole which main function is to detect changes in pressure
MACULA DENSA
17
The fluid inside the bowman's space is called
ULTRAFILTRATE
18
What are the factors affecting the glomerular filtration
FILTRATION BARRIER, NET FILTRATION PRESSURE, RENIN ANGIOTENSIN ALDOSTERONE SYSTEM
19
Filtration barrier is composed of
FENESTRATED ENDOTHELIUM, BASEMENT MEMBRANE, VISCERAL EPITHELIUM
20
It is a filtration barrier that increases the permeability due to its pores
FENESTRATED ENDOTHELIUM, MESANGIUM
21
It is a smooth muscle in the penetrated endothelium which functions for contraction phagocytosis and pinocytosis
MESANGIUM
22
How many nanometers do fenestrated endothelium
50-100
23
This is the filtration barrier which provides for the restriction main size discriminant barrier to protein passage
BASEMENT MEMBRANE
24
Filtration barrier that separates epithelium of the urinary space from the endothelium of glomerular capillaries
BASEMENT MEMBRANE
25
Characterized by intertwining foot processes which forms forms filtration slits
VISCERAL EPITHELIUM, PODOCYTE
26
Lines davao man's space which is like a finger like processes
PODOCYTE
27
Podocytes are intertwining foot processes with finger like extension which is separated from each other about how many nanometers
20-30
28
Afforded by negatively charged components which provides additional restriction by refilling negatively charged molecules like albumin and plasma proteins
SHIELD OF NEGATIVITY
29
What are the three forces involved for the net filtration pressure
GLOMERULAR BLOOD HYDROSTATIC PRESSURE, CAPSULAR HYDROSTATIC PRESSURE, BLOOD COLLOID OSMOTIC PRESSURE
30
The pressure that forces substances like protein free filtrate from the glomerular capillaries into the bowman's capsule
NET FILTRATION PRESSURE
31
This is the capillary blood hydrostatic pressure usually measures about 60 mmhg
GLOMERULAR BLOOD HYDROSTATIC PRESSURE
32
This is the pressure in the glomerular capillary forcing water and its solutes through filtration slits
GLOMERULAR BLOOD HYDROSTATIC PRESSURE
33
Chp and bchp are also known as
OPPOSING PRESSURE
34
This is the pressure exerted against the filtration membrane by fluid that is already in the capsular space
CAPSULAR HYDROSTATIC PRESSURE
35
It is a pressure exerted by the proteins in the blood plasma
BLOOD COLLOID OSMOTIC PRESSURE
36
The formula in computing the net outward pressure
GBHP-CHP-BCHP
37
It directly affects the kidneys functional ability
RENAL BLOOD FLOW
38
How many percent of cardiac output goes to the kidneys
25%
39
What is the total renal blood flow
1200 ML/MIN
40
What is the total renal plasma flow
600-700 ML/MIN
41
It is a capillary bed that surround the convulated tubules which function as the vascular supply
PERITUBULAR CAPILLARY
42
It is the capillary bed that surrounds the loop of henle which function to receive water and solutes so that it can be turn it back to circulation
VASA RECTA
43
It drains blood from the kidneys
RENAL VEIN
44
Renal
u
45
Rate of filtration in the glomerulus which processes involves the filtration of blood which leads to formation of the ultra filtrate
GLOMERULAR FILTRATION
46
It serves as a non-selective filter or sieve of plasma substances with a molecular weight of less than 70,000
GLOMERULUS
47
What are the parts of the renal tubules
PROXIMAL CONVOLUTED TUBULE, LOOP OF HENLE, DISTAL CONVOLUTED TUBULE, COLLECTING DUCT
48
It is the most convulated tubule which is the straight portion which becomes the loop of henle once it reaches the medulla
PROXIMAL CONVOLUTED TUBULE
49
Renal tubule composed of thin descending segment u shape segment and thick and thin ascending segment
LOOP OF HENLE
50
Renal tubule composed of 2-3 loops only that begins at the juxtaglomerular apparatus with the macula densa
DISTAL CONVOLUTED TUBULE
51
This tubule tra versus the renal cortex and medola which serves as the site of final urine concentration
COLLECTING DUCT
52
What is the epithelium of proximal convoluted tubule
INTERDIGITATING WITH MICROVILLI
53
This is the part of brush border epithelium of proximal convulated tubule which functions for reabsorption of nutrients
MICROVILLI
54
It is a part of the renal tubule which is responsible for 60% of nutrient reabsorption
PROXIMAL CONVOLUTED TUBULE
55
Is the characteristics of finger like appearance of epithelium
INTERDIGITATING EPITHELIUM
56
The first segment of the loop of henle
THIN DESCENDING SEGMENT
57
Thin descending segment is made up of what cell and epithelium
NON INTERDIGITATING, FLAT
58
It is also known as u shaped segment which is a part of loop of henle made up of flat cells and extensively interdigitating epithelium
HAIRPIN
59
What cells made up thin ascending loop of henle
FLAT
60
What cell and epithelium made up the thick ascending loop of henle
TALL, INTERDIGITATING EPITHELIUM
61
It is a segment of loop of henle with high mitochondrial and enzymatic activity in the 2/3 of the distal basal layer
THICK ASCENDING SEGMENT
62
What segment of loop of henley is permeable to water
THIN ASCENDING SEGMENT
63
Segment of loop of henle which is in permeable to water which is permeable to sodium chloride
THIN DESCENDING SEGMENT
64
It regulates the blood flow and within the glomerulus
RENIN ANGIOTENSIN ALDOSTERONE SYSTEM
65
What part of the raas system which the distal convoluted tubule and efferent arteriole meets
JUXTAGLOMERULAR APPARATUS
66
It responds to changes in blood pressure and plasma sodium concentration
RENIN ANGIOTENSIN ALDOSTERONE SYSTEM
67
What is the triggering mechanism of the RAAS
LOW PLASMA SODIUM CONCENTRATION, LOW BLOOD PRESSURE
68
It is also known as the sodium retaining hormone which is secreted by adrenal cortex
ALDOSTERONE
69
This hormone increases the water reabsorption
VASOPRESSIN
70
Angiotensin
phyo
71
What hormone increases the sodium reabsorption in the dct
ALDOSTERONE
72
How many percent of ultrafiltrate is excreted in the urine
1%
73
This is the movement of molecules from the tubular capillaries to the tubular lumen
TUBULAR REABSORPTION
74
The movement of substances from capillaries and instertitial to the tubular lumen
TUBULAR SECRETION
75
Reabsorption is made possible by the what structure
MICROVILLI
76
The maximum limit of renal tubules can reabsorbs certain substances
RENAL THRESHOLD
77
These are the two mechanisms that is needed for tubular reabsorption and renal threshold
ACTIVE TRANSPORT, PASSIVE TRANSPORT
78
It is a type of active transport which needs carrier protein to pass through
INDIRECT TRANSPORT
79
It is an active transport that needs ATP or energy to pass through
DIRECT TRANSPORT
80
Movement of molecules across a membrane by diffusion becauseof a physical gradient which doesn't need energy as concentration is from high to low level
PASSIVE TRANSPORT
81
This is a reabsorption mechanism which transfer of substances is brought about by the electrochemical energy and substance must combine with a carrier protein or an energy
ACTIVE TRANSPORT
82
Movement of substances from the blood in renal capillary beds to the filtrate in the tubular lumen
TUBULAR SECRETION
83
What are the two major function of tubular secretion
ELIMINATION OF WASTE PRODUCT, REGULATION OF ACID AND BASE
84
The normal blood ph
7.35-7.45
85
This is when after eating and urine is collected acidic caused by the production of carbon dioxide from the oxidative metabolism of food and catabolism of proteins and phosphate
ALKALINE TIDE
86
What are the three mechanisms for acid base balance of the body
BLOOD BUFFER, PULMONARY, RENAL SYSTEM
87
Monosodium phosphate that was excreted in the urine
TITRABLE ACID
88
Titrable acid has the ability to titrate urine into what ph
7.4
89
Hormone that Responds to the body's need for Na and promotes Na reabsorption in the DCT
ALDOSTERONE
90
Responds to the body's need for water and promotes water reabsorption in the DCT and CD
VASOPRESSIN
91
Countercurrent Mechanism in DLH
WATER REABSORPTION
92
Countercurrent Mechanism in ALH
SODIUM AND CHLORIDE REABSORPTION
93
Essential substances are returned to the circulation. Substances are transported from the flitrate back to the blood
TUBULAR REABSORPTION
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