問題一覧
1
Which of the following is not a type of study design?
Pilot study
2
What effect does increasing the sample size have upon the random error?
It reduces the random error
3
Before initiating the study, the Principal Investigator must ensure that various approvals are obtained. Which of the following approvals is/are absolutely mandatory?
Ethics committee approval
4
The following statements describe confounding and effect modification. Which of the statement is/are correct?
'a' and 'b' are correct
5
Which of the following will best describe the scientific inquiry that seeks to understand the acceptability and functionality of a health program?
Implementation research
6
Which of the following statement is incorrect about a good research question?
Feasibility should not be a criterion while developing research question
7
All the following are components of 'FINER ' criteria for a research question EXCEPT
Reliable
8
The following are the steps in framing a research question. I. Review of state-of-art information II.Define measurable exposures & outcomes III. Raise a question IV. Decide worth investigating by peer-review Choose the correct sequence of framing a research question from below.
I, III, IV, II
9
The process of refining the "ideas" into research questions begins with general uncertainty about a health issue and narrow down to a specific, concrete researchable issue
True
10
As per the following objectives a hypothesis should be stated for which study?
To determine the association of maternal smoking during pregnancy with respiratory infectious disease morbidity and mortality in infants
11
The ability to apply the principles of analysis to identify those studies which are unbiased and valid is called as
Critical appraisal
12
Which of the following is unethical while writing a Literature Review?
It is not necessary to address the weakness of the study in a scholarly manner
13
All the following about literature review is correct EXCEPT
It helps the researcher in arriving the conclusion of a study
14
Literature searches are important to do at the start of a project; and do not need to continue throughout the project.
False
15
Which of the following about MeSH is incorrect?
MeSH is used for EMBASE database
16
In a study among 3400 children aged 5-10 years, 16 children were diagnosed with autistic disorder. Calculate the prevalence of autism per 1000 children
4.71
17
What is the appropriate epidemiologic measure to determine the severity of an acute disease?
Case fatality ratio
18
When measuring the frequency for an acute infectious disease in a community in terms of incidence per 1000 persons per year and point prevalence per 1000 persons, how will the pattern of incidence and prevalence be?
Low prevalence and high incidence
19
This measure reflects the impact of a disease on population in terms of death
Disease specific mortality
20
Which of the following is true about incidence density?
Numerator has number of new cases
21
Which one of the following is useful to measure the burden or magnitude of a disease or risk factor?
Cross-sectional study
22
In a tertiary care hospital, a surgeon collected information on quality of life and outcome among a small group of (about 15) post-operative patients after using a novel surgical device. But this is not sufficient to establish the efficacy of the surgical device because
There is no comparison group
23
If a researcher wishes to estimate the incidence of Myocardial infarction cases among a group of women using oral contraceptive pills followed up for 10 year, the researcher has to carry out
Cohort study
24
A researcher can assess the following by conducting a descriptive study EXCEPT
Risk factors of the disease
25
Which of the following is wrong about descriptive study designs?
Compare the study outcomes for 2 group
26
What is an appropriate measure of statistical association in a cohort study?
Risk ratio
27
If the odds of exposure among cases is lower than the odds of exposure among the controls, the odds ratio will be
Less than 1
28
Relative risk of more than 1 indicates
Incidence in exposed is higher than unexposed
29
Which of the following is NOT true regarding casecontrol study? i. Appropriate for study of rare outcome ii. More time consuming than cohort study iii. Multiple exposures can be examined iv. Relatively expensive compared to cohort study
Both (ii) and (iv)
30
Cohort study is suitable for rare diseases
False
31
Which of the following is incorrect in case of a clinical trial?
All clinical trials must be blinded
32
All the following correctly describe a clinical trial, EXCEPT-
Loss to follow up of study participants does not affect the study outcome
33
In a clinical trial, what is the main purpose of randomization?
To get groups with comparable baseline characteristics
34
The purpose of a double-blinding in a clinical trial is to
Avoid observer and participant bias
35
A pharmacologically inactive agent that investigators administer to participants in the control group of a trial
Placebo
36
All are true regarding measures to reduce information bias, EXCEPT
Adequate sample size
37
Systematic distortion of the truth by study subjects is called as
Prevarication
38
Biases can occur during which stage of research study?
At any of the above stages
39
Better recall of exposure only among the cases in a case control study can result in
Information bias
40
Crude association in the presence of a confounder is the actual causal association
False
41
Which methods in qualitative research use flexible interview guide?
Focus Group Discussions and In-depth interviews
42
The qualitative data analysis method which uses theoretical framework as the basis for analysis
Content analysis
43
Which of the following statement is true regarding Participant Observation
Observer becomes a part of the event/group
44
Which of the following statement is “False” about focus group discussion.
Heterogeneity of the group is a pre-requisite
45
The main methods used in qualitative research method include all EXCEPT
Structured questionnaire-based interviews
46
Find the median in the following sample of observations: 12, 26, 10, 29, 48
26
47
A researcher measures fasting blood level of glucose of 100 participants. The mean blood sugar level was measured as 110 mg/dl. The standard deviation was 11 mg/dl. Calculate the coefficient of variance.
10%
48
Which of the following is true about inter-quartile range?
It covers the middle 50% of observations
49
In a study, researchers are interested in measuring the cholesterol levels of participants. Cholesterol level is a ________ variable
Continuous
50
In a study, a researcher was interested in measuring the haemoglobin levels of 10 participants. The values are 10.0, 8.5, 12.0, 14.0, 11.5, 13.5, 9.0, 12.0, 11.3, 7.5. What is the mode of this distribution?
12.0
51
The following statement is correct regarding sampling error
The magnitude of error can be measured in probability samples
52
Which of the following is true about non-probability sampling?
Quota sampling is a type of non-probability sampling
53
The magnitude of sampling error can be measured in probability sampling.
True
54
People who volunteer or who can be easily recruited are used in a sampling method called
Convenience sampling
55
The list of all individuals in the study population from whom study participants in a research are to be selected is known as
Sampling frame
56
The recommended minimum level of power for an analytical study
80%
57
All the following are essential statistical considerations for sample size calculation EXCEPT
Allocated budget
58
A researcher wants to estimate the prevalence of surgical site infection following cesarean section at a tertiary care hospital. What would be the minimum number of sample size to estimate the magnitude of surgical site infection following cesarean section if it is estimated that the proportion of surgical site infection will be 10% in the hospital considering 5% absolute precision and 95% confidence level (Z α/2 = 1.96).
138
59
The power of a study
Can be defined as the probability of correctly rejecting null hypothesis when it is false
60
Population variance can be estimated from
a' and 'b'
61
External validity means
The degree to which the inferences drawn from a study can be generalized to a broader population beyond the study population
62
The population defined by clinical and demographic characteristics is called
Target population
63
Which factor is important to consider while choosing the accessible population and the sampling approach?
Feasibility
64
The degree to which the observed findings lead to correct inferences about phenomena of interest in the study sample is
Internal validity
65
Random errors can be effectively handled by
Adequate sample size
66
Which of the following can be considered true in case of ad hoc approach to conduct a research study?
Only 'a'
67
Study conducted following an ad hoc approach may lead to the following consequences
Serious interpretation difficulties in analysis and interpretation
68
Smart objectives are goals that are designed to be be specific, measurable, achievable, relevant and timebound. Which of the following is an illustration of nonmeasurable objective?
Experiences shared by victims of domestic violence
69
A study began in 1980 with enrollment of a group of 7000 adults in Pondicherry who were asked about their alcohol consumption, smoking, diet, environmental risk factors etc. All the participants were periodically examined and evaluated for evidence of various types of cancers between 1990-1995. Which of the following study designs was used by the investigators?
Prospective cohort study
70
Indicators are considered positive when they have a direct relationship (association, correlation) with the state of health. Which of the following are the examples of positive indicators? a) The proportion of cured tuberculosis cases b) Incidence of AIDS c) Life expectancy at birth
a' and 'c
71
The interviewer does not provide options for responses in
Open-ended questions
72
The information about participant's attitudes for behaviors such as wearing helmets, washing hands before eating, constitute
Judgments
73
An investigator wanted to study the clinical profile of patients presented with foreign body in nose, attended in the emergency department in the last 2 years in a hospital. Which of the following is the most suitable way to collect data?
Review of records
74
Which of the following is correct in relation to an open question?
Stimulate memory
75
Order of a question should be all, EXCEPT-
From intimate to casual
76
This should not be done in data collection
Manipulation of data
77
Who is mainly responsible to check the accuracy of data collection instruments before leaving the location?
Field supervisor
78
Which one of the following is the proper way of validating the data?
Repetition of data collection in a randomly selected subset in the same population
79
All the following statements are true about training of the data collectors, except-
Onsite training is not essential for data collectors
80
Supportive supervision is essential for a good data collection process
True
81
In a data management system, each row represents a
Record
82
A researcher in diabetes expected that that the fasting blood sugar levels may take any value between 50 and 150 gm/dL. In this research any coding of missing value as 99 may lead to an erroneous result.
True
83
Which of the following is incorrect about normalized database?
c) Normalized database does not facilitate further data aggregation
84
A post-graduate researcher has completed the data collection for her thesis. During data management, she should do all the following, EXCEPT-
Applying for the ethics committee clearance
85
While documenting the storage information of the database, we need to document
Media, location and backup information
86
In analytical stage of data analysis, we perform the following in order
Univariate analysis, stratified analysis and multivariate analysis
87
Among the seven steps of data analysis strategy, the sequence of data analysis is as follows (A) Conduct advanced analysis (B) Identify main variables (C) Become familiar with the data (D) Identify study type (E) Examine outcome/exposure association (F) Characterize study population (G) Create additional two-way tables
D, B, C, F, E, G, A
88
If we are doing an analytical study and the study outcome is of acute nature and a frequent condition what is the appropriate (i) study design and (ii) measure of association?
Cohort study - relative risk
89
In case of descriptive studies, which of the following is wrong?
We compare the study outcome for 2 groups
90
Multivariate regression models are used during the descriptive stage of analysis
False
91
As part of evaluation of a new vaccine which requires taking a daily oral dose of a refrigerated vaccine, the research team offers to provide a refrigerator to families of participants who don’t have one. Which of the following ethical issues the Institutional Ethics Committee will have to deal with while reviewing the research study?
Undue inducement
92
Which of the following is not true about an Informed Consent?
IC taken by coercion is considered valid
93
In the middle of a clinical trial, one participant decides to withdraw from the trial. But, the investigator pressurizes the participant to continue in the study till it completes. Which of the following ethical principles does the investigator violate?
Autonomy
94
While conducting research among tribal populations, which of the following is recommended?
Consent from the tribal head (Group consent) is desirable
95
Do no harm" concept was emphasized in which of the following ethical principles?
Non-Maleficence
96
In which of the following guidelines, discussion on rationale and justification of risk benefit analysis of research and voluntary consent in research was initiated?
Nuremberg code
97
In which type of the following study/studies is (are) informed consent not necessary?
Analysis of mortality data of 2001-2010
98
Which of the following statements regarding document storage and archival after the conclusion of a trial; is correct?
Archival for a period of 5 - 15 years as per the requirement of the sponsor may be necessary
99
Which of the following is NOT a method for identifying and preventing potential harm to study participants?
Close watch on enrolment targets
100
Bodies like Drug Controller General of India (DCGI) and Health Ministry Screening Committee (HMSC) are concerned with the following
Regulatory review