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100問 • 1年前
  • Yves Laure Pimentel
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    問題一覧

  • 1

    When the red cells of an individual fail to react with anti-U, they usually fail to react with: anti-M anti-Le anti-S anti-Py

    anti-S

  • 2

    Which of the following red cell antigens are found on glycophorin-A? M,N Le^a, Le^b S,s P1P1, Pk

    M,N

  • 3

    Paroxysmal cold hemoglobinuria (PCH) is associated with antibody specificity toward which of the following? a Kell system antigens b Duffy system antigens c P antigen d l antigen

    c P antigen

  • 4

    Which of the following is a characteristic of anti-i? a associated with warm autoimmune hemolytic anemia b found in the serum of patients with infectious mononucleosis c detected at lower temperatures in the serum of normal individuals d found only in the serum of group O individuals

    b found in the serum of patients with infectious mononucleosis

  • 5

    In a case of cold autoimmune hemolytic anemia, the patient’s serum would most likely react 4+ at immediate spin with: group A cells, B cells and O cells, but not his own cells cord cells but not his own or other adult cells all cells of a group O cell panel and his own cells only penicillin-treated panel cells, not his own cells

    all cells of a group O cell panel and his own cells

  • 6

    Cold agglutinin syndrome is associated with an antibody specificity toward which of the following? a Fy:3 b P c I d Rh:1

    c I

  • 7

    Which of the following is a characteristic of anti-i? often associated with hemolytic disease of the newborn reacts best at room temperature or 4°C reacts best at 37°C is usually IgG

    reacts best at room temperature or 4°C

  • 8

    The Kell (K1) antigen is: a absent from the red cells of neonates b strongly immunogenic c destroyed by enzymes d has a frequency of 50% in the random population

    b strongly immunogenic

  • 9

    In chronic granulomatous disease (CGD), granulocyte function is impaired. An association exists between this clinical condition and a depression of which of the following antigens? Rh P Kell Duffy

    Kell

  • 10

    The antibodies of the Kidd blood group system: react best by the indirect antiglobulin test are predominantly IgM often cause allergic transfusion reactions do not generally react with antigen-positive, enzyme-treated RBCs

    react best by the indirect antiglobulin test

  • 11

    Proteolytic enzyme treatment of red cells usually destroys which antigen? a Jk^a b E c Fy^a d k

    c Fy^a

  • 12

    Anti-Fy^a is: usually a cold-reactive agglutinin more reactive when tested with enzyme-treated red blood cells capable of causing hemolytic transfusion reactions often an autoagglutinin

    capable of causing hemolytic transfusion reactions

  • 13

    Resistance to malaria is best associated with which of the following blood groups? a Rh b I/i c P d Duffy

    d Duffy

  • 14

    What percent of group O donors would be compatible with a serum sample that contained anti-X and anti-Y if X antigen is present on red cells of 5 of 20 donors, and Y antigen is present on red cells of 1 of 10 donors? a 2.5 b 68 c 25.0 d 68.0

    d 68.0

  • 15

    How many Caucasians in a population of 100,000 will have the following combination of phenotypes? a 1 b 14 c 144 d 1,438

    d 1,438

  • 16

    What is the approximate probability of finding compatible blood among random Rh-positive units for a patient who has anti-c and anti-K? (Consider that 20% of Rh-positive donors lack c and 90% lack K) 1% 10% 18% 45%

    18%

  • 17

    A 25-year-old Caucasian woman, gravida 3, para 2, required 2 units of Red Blood Cells. The antibody screen was positive and the results of the antibody panel are shown below:

    d

  • 18

    Aman suffering from gastrointestinal bleeding has received 20 units of Red Blood Cells in the last 24 hours and is still oozing post-operatively. The following results were obtained: What blood product should be administered? a Fresh Frozen Plasma b Red Blood Cells c Factor VIII Concentrate d Platelets

    a Fresh Frozen Plasma

  • 19

    Transfusion of which of the following is needed to help correct hypofibrinogenemia due to DIC? Whole Blood Fresh Frozen Plasma Cryoprecipitated AHF Platelets

    Cryoprecipitated AHF

  • 20

    blood component used in the treatment of hemophilia A is: Factor VIII Concentrate Fresh Frozen Plasma Platelets Whole Blood

    Factor VIII Concentrate

  • 21

    Which of the following blood components is most appropriate to transfuse to an 8-year-old male hemophiliac who is about to undergo minor surgery? Cryoprecipitated AHF Red Blood Cells Platelets Factor VIII Concentrate

    Factor VIII Concentrate

  • 22

    A unit of Fresh Frozen Plasma was inadvertently thawed and then immediately refrigerated at 4°C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement for: a_ all coagulation factors b Factor V ec Factor VIII d Factor IX

    d Factor IX

  • 23

    A newborn demonstrates petechiae, ecchymosis and mucosal bleeding. The preferred blood component for this infant would be: a Red Blood Cells b Fresh Frozen Plasma c Platelets d Cryoprecipitated AHF

    c Platelets

  • 24

    Which of the following would be the best source of Platelets for transfusion in the case of alloimmune neonatal thrombocytopenia? a father b mother c pooled platelet-rich plasma d polycythemic donor

    b mother

  • 25

    An obstetrical patient has had 3 previous pregnancies. Her first baby was healthy, the second was jaundiced at birth and required an exchange transfusion, while the third was stillborn. Which of the following is the most likely cause? a ABO incompatibility b immune deficiency disease c congenital spherocytic anemia d Rh incompatibility

    d Rh incompatibility

  • 26

    A specimen of cord blood is submitted to the transfusion service for routine testing. The following results are obtained: It is known that the father is group B, with the genotype of cde/cde. Of the following 4 antibodies, which 1 is the most likely cause of the positive direct antiglobulin test? a anti-A b anti-D ¢ anti-c d anti-C

    ¢ anti-c

  • 27

    ABO-hemolytic disease of the newborn: a usually requires an exchange transfusion b most often occurs in first born children c frequently results in stillbirth d is usually seen only in the newborn of group O mothers

    d is usually seen only in the newborn of group O mothers

  • 28

    Which of the following antigens is most likely to be involved in hemolytic disease of the newborn? a Le^a b P1 c M d Kell

    d Kell

  • 29

    ABO hemolytic disease of the fetus and newborn (HDFN) differs from Rh HDFN in that: a Rh HDFN is clinically more severe than ABO HDFN b the direct antiglobulin test is weaker in Rh HDFN than ABO c RhHODEN occurs in the first pregnancy d_ the mother’s antibody screen is positive in ABO HDN

    a Rh HDFN is clinically more severe than ABO HDFN

  • 30

    The following results were obtained: Which of the following is the most probable explanation for these results? a ABO hemolytic disease of the fetus and newborn b Rh hemolytic disease of the fetus and newborn; infant has received intrauterine transfusions c Rhhemolytic disease of the fetus and newborn, infant has a false-negative Rh typing d large fetomaternal hemorrhage

    c Rhhemolytic disease of the fetus and newborn, infant has a false-negative Rh typing

  • 31

    A group A, Rh-positive infant of a group O, Rh-positive mother has a weakly positive direct antiglobulin test and a moderately elevated bilirubin 12 hours after birth. The most likely cause is: a ABO incompatibility b Rh incompatibility c blood group incompatibility due to an antibody to a low frequency antigen d neonatal jaundice not associated with blood group

    a ABO incompatibility

  • 32

    In suspected cases of hemolytic disease of the newborn, what significant information can be obtained from the baby’s blood smear? a estimation of WBC, RBC, and platelet counts b marked increase in immature neutrophils (shift to the left) c a differential to estimate the absolute number of lymphocytes present d_ determination of the presence of spherocytes

    d_ determination of the presence of spherocytes

  • 33

    The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid: a_ bilirubin concentration by standard methods b change in optical density measured at 450 nm ¢ Rh determination d ratio of lecithin to sphingomyelin

    b change in optical density measured at 450 nm

  • 34

    These laboratory results were obtained on maternal and cord blood samples: mother: A- baby: AB+, DAT: 3+ cord hemoglobin: 10 g/dL (100 g/L) Does the baby have HDN? a no, as indicated by the cord hemoglobin b yes, although the cord hemoglobin is normal, the DAT indicates HDN ¢ yes, the DAT and cord hemoglobin level both support HDN d_ no, a diagnosis of HDN cannot be established without cord bilirubin levels

    ¢ yes, the DAT and cord hemoglobin level both support HDN

  • 35

    The main purpose of performing antibody titers on serum from prenatal immunized women is to: a determine the identity of the antibody b identify candidates for amniocentesis or percutaneous umbilical blood sampling c decide if the baby needs an intrauterine transfusion d_ determine if early induction of labor is indicated

    b identify candidates for amniocentesis or percutaneous umbilical blood sampling

  • 36

    Which unit should be selected for exchange transfusion if the newborn is group A, Rh-positive and the mother is group A, Rh-positive with anti-c? a A, CDe/CDe b A, cDE/cDE c O,cde/cde d A, cde/cde

    a A, CDe/CDe

  • 37

    A mother is group A, with anti-D in her serum. What would be the preferred blood product if an intrauterine transfusion is indicated? a O, Rh-negative Red Blood Cells b O, Rh-negative Red Blood Cells, Irradiated c A, Rh-negative Red Blood Cells d A, Rh-negative Red Blood Cells, Irradiated

    b O, Rh-negative Red Blood Cells, Irradiated

  • 38

    Laboratory studies of maternal and cord blood yield the following results: Maternal blood Cord blood O, Rh-negative B, Rh-positive anti-E in serum DAT = 2+ anti-E in eluate If exchange transfusion is necessary, the best choice of blood is: a _ B, Rh-negative, E+ b_ B, Rh-positive, E+ c_ O, Rh-negative, Ed O, Rh-positive, E

    d O, Rh-positive, E

  • 39

    A blood specimen from a pregnant woman is found to be group B, Rh-negative and the serum contains anti-D with a titer of 512. What would be the most appropriate type of blood to have available for a possible exchange transfusion for her infant? O, Rh-negative O, Rh-pasitive B, Rh-negative B, Rh-positive

    O, Rh-negative

  • 40

    Blood selected for exchange transfusion must: a_ lack red blood cell antigens corresponding to maternal antibodies b be <3 days old c be the same Rh type as the baby d be ABO compatible with the father

    a_ lack red blood cell antigens corresponding to maternal antibodies

  • 41

    When the main objective of an exchange transfusion is to remove the infant’s antibody-sensitized red blood cells and to control hyperbilirubinemia, the blood product of choice is ABO compatible: Fresh Whole Blood Red Blood Cells (RBC) washed RBC suspended in Fresh Frozen Plasma heparinized Red Blood Cells

    RBC suspended in Fresh Frozen Plasma

  • 42

    To prevent graft-vs-host disease, Red Blood Cells prepared for infants who have received intrauterine transfusions should be: a saline-washed b irradiated c frozen and deglycerolized d group- and Rh-compatible with the mother

    b irradiated

  • 43

    Which of the following is the preferred specimen for the initial compatibility testing in exchange transfusion therapy? a maternal serum b eluate prepared from infant’s red blood cells ¢ paternal serum d infant’s postexchange serum

    a maternal serum

  • 44

    Rh-Immune Globulin is requested for an Rh-negative mother who has the following results: What is the most likely explanation? a mother is a genetic weak D b mother had a fetomaternal hemorrhage of D+ cells ¢« mother’s red cells are coated weakly with IgG d anti-D reagent is contaminated with an atypical antibody

    b mother had a fetomaternal hemorrhage of D+ cells

  • 45

    The following results are seen on a maternal postpartum sample: The most appropriate course of action is to: a report the mother as Rh-negative b report the mother as Rh-positive ¢ perform an elution on mother’s RBCs d investigate for a fetomaternal hemorrhage

    d investigate for a fetomaternal hemorrhage

  • 46

    What is the most appropriate interpretation for the laboratory data given below when an Rh-negative woman has an Rh-positive child? Rosette fetal screen using enzyme-treated D+ cells mother’s sample: 1 rosette/3 fields positive control: 5 rosettes/3 fields negative control: no rosettes observed Mother is not a candidate for Rhlg mother needs 1 vial of Rhlg mother needs 2 vials of Rhlg the fetal-maternal hemorrhage needs to be quantitated

    Mother is not a candidate for Rhlg

  • 47

    Refer to the following information: What is the best interpretation for the laboratory data given above? a mother is Rh-positive b mother is weak D+ ¢ mother has had a fetal-maternal hemorrhage d mother has a positive DAT

    ¢ mother has had a fetal-maternal hemorrhage

  • 48

    a weakly reactive anti-D is detected in a postpartum specimen from an Rh-negative woman. During her prenatal period, all antibody screening tests were negative. These findings indicate: a_ that she is a candidate for Rh immune globulin b that she is not a candidate for Rh immune globulin c a need for further investigation to determine candidacy for Rh immune globulin d_ the presence of Rh-positive cells in her circulation

    c a need for further investigation to determine candidacy for Rh immune globulin

  • 49

    Th e results of a Kleihauer-Betke stain indicate a fetomaternal hemorrhage of 35 mL of whole blood. How many vials of Rh immune globulin would be required? a 1 b 2 c 3 d 4

    b 2

  • 50

    fetomaternal hemorrhage of 35 mL of fetal Rh-positive packed RBCs has been detected in an Rh-negative woman. How many vials of Rh immune globulin should be given? 0 1 2 3

    3

  • 51

    Criteria determining Rh immune globulin eligibility include: mother is Rh-positive infant is Rh-negative mother has not been previously immunized to the D antigen infant has a positive direct antiglobulin test

    mother has not been previously immunized to the D antigen

  • 52

    hile performing routine postpartum testing for an Rh immune globulin (RhIG) candidate, a weakly positive antibody screening test was found. Anti-D was identified. This antibody is most likely the result of: a massive fetomaternal hemorrhage occurring at the time of this delivery b antenatal administration of Rh immune globulin at 28 weeks gestation ¢ contamination of the blood sample with Wharton jelly d_ mother having a positive direct antiglobulin test

    b antenatal administration of Rh immune globulin at 28 weeks gestation

  • 53

    Rh immune globulin administration would not be indicated in an Rh-negative woman who has a(n): first trimester abortion husband who is Rh-positive anti-D titer of 1:4,096 positive direct antiglobulin test

    anti-D titer of 1:4,096

  • 54

    A Kleihauer-Betke stain of a postpartum blood film revealed 0.3% fetal cells. What is the estimated volume (mL) of the fetomaternal hemorrhage expressed as whole blood? 5 15 25 35

    25

  • 55

    Based upon Kleihauer-Betke test results, which of the following formulas is used to determine the volume of fetomaternal hemorrhage expressed in mL of whole blood? % of fetal cells present x 30 % of fetal cells present x 50 % of maternal cells present x 30 % of maternal cells present x 50

    % of fetal cells present x 50

  • 56

    An acid elution stain was made using a 1-hour post-delivery maternal blood sample. Out of 2,000 cells that were counted, 30 of them appeared to contain fetal hemoglobin. It is the policy of the medical center to add 1 vial of Rh immune globulin to the calculated dose when the estimated volume of the hemorrhage exceeds 20 mL of whole blood. Calculate the number of vials of Rh immune globulin that would be indicated under these circumstances. a 2 b 3 c 4 d 5

    c 4

  • 57

    The rosette test will detect a fetomaternal hemorrhage (FMH) as small as: a 10mL b 15mL c 20mL d 30 mL

    a 10mL

  • 58

    A10 mL fetal maternal hemorrhage in an Rh-negative woman who delivered an Rh-positive baby MLS ony means that the: mother’s antibody screen will be positive for anti-D rosette test will be positive mother is not a candidate for Rh immune globulin mother should receive 2 doses of Rh immune globulin

    rosette test will be positive

  • 59

    Mixed leukocyte culture (MLC) is a biclogical assay for detecting which of the following? HLA-A antigens HLA-B antigens HLA-D antigens immunoglobulins

    HLA-D antigens

  • 60

    A 40-year-old man with autoimmune hemolytic anemia due to anti-E has a hemoglobin level of 10.8 g/dL (108 g/L). This patient will most likely be treated with: a Whole Blood b Red Blood Cells c Fresh Frozen Plasma d no transfusion

    d no transfusion

  • 61

    patient in the immediate post bone marrow transplant period has a hematocrit of 21%. The red cell product of choice for this patient would be: packed saline washed microaggregate filtered irradiated

    irradiated

  • 62

    HLA antigen typing is important in screening for: ABO incompatibility a kidney donor Rh incompatibility a blood donor

    a kidney donor

  • 63

    DR antigens in the HLA system are: expressed on platelets expressed on granulocytes significant in organ transplantation not detectable in the lymphocytotoxicity test

    expressed on platelets

  • 64

    Anti-E is identified in a panel at the antiglobulin phase. When check cells are added to the tubes, no agglutination is seen. The most appropriate course of action would be to: quality control the AHG reagent and check cells and repeat the panel open a new vial of check cells for subsequent testing that day open a new vial of AHG for subsequent testing that day record the check cell reactions and report the antibody panel result

    quality control the AHG reagent and check cells and repeat the panel

  • 65

    A serological centrifuge is recalibrated for ABO testing after major repairs. Given the data above, the centrifuge time for this machine should be: a 15 seconds b 20 seconds c 25 seconds d 30 seconds

    b 20 seconds

  • 66

    Which of the following represents an acceptably identified patient for sample collection and transfusion? a a handwritten band with patient’s name and hospital identification number is affixed to the patient's leg b_ the addressographed hospital band is taped to the patient’s bed ¢ anunbanded patient responds positively when his name is called d_ the chart transported with the patient contains his armband not yet attached

    a a handwritten band with patient’s name and hospital identification number is affixed to the patient's leg

  • 67

    Samples from the same patient were received on 2 consecutive days. Test results are summarized below: How should the request for crossmatch be handled? a crossmatch A, Rh-positive units with sample from day 1 b crossmatch B, Rh-positive units with sample from day 2 ¢ crossmatch AB, Rh-positive units with both samples d collect anew sample and repeat the tests

    d collect anew sample and repeat the tests

  • 68

    The following test results are noted for a unit of blood labeled group A, Rh-negative: Cells tested with: anti-A anti-B anti-D 4+ 0 3+ What should be done next? a transfuse as a group A, Rh-negative b transfuse as a group A, Rh-positive ¢ notify the collecting facility d discard the unit

    ¢ notify the collecting facility

  • 69

    What information is essential on patient blood sample labels drawn for compatibility testing? a_ biohazard sticker for AIDS patients b patient’s room number ¢ unique patient medical number d_ phiebotomist initials

    ¢ unique patient medical number

  • 70

    Granulocytes for transfusion should: a_ be administered through a microaggregate filter b be ABO compatible with the recipient’s serum c be infused within 72 hours of collection d never be transfused to patients with a history of febrile transfusion reactions

    b be ABO compatible with the recipient’s serum

  • 71

    A neonate will be transfused for the first time with group O Red Blood Cells. Which of the following is appropriate compatibility testing? crossmatch with mother’s serum crossmatch with baby’s serum no crossmatch is necessary if initial plasma screening is negative no screening or crossmatching is necessary for neonates

    no crossmatch is necessary if initial plasma screening is negative

  • 72

    A group B, Rh-negative patient has a positive DAT. Which of the following situations would occur? a_ all major crossmatches would be incompatible b the weak D test and control would be positive c_ the antibody screening test would be positive d_ the forward and reverse ABO groupings would not agree

    b the weak D test and control would be positive

  • 73

    ‘The following reactions were obtained: Cells tested with: Serum tested with: anti-A anti-B anti-A,B A1 cells B cells 4+ 3+ 4+ 1+ 4+ The technologist washed the patient’s cells with saline, and repeated the forward typing. A saline replacement technique was used with the reverse typing. The following results were obtained: Cells tested with: Serum tested with: anti-A anti-B anti-A,B A1 cells Bcells 4+ 0 4+ 0 A+ The results are consistent with: a acquired immunodeficiency disease b Bruton agammaglobulinemia c multiple myeloma d acquired “B” antigen

    c multiple myeloma

  • 74

    What is the most likely cause of the following ABO discrepancy? Patient's cells vs: Patient’s serum vs: anti-A anti- B A1 cells B cells 0 0 0 0 recent transfusion with group O blood antigen depression due to leukemia false-negative cell typing due to rouleaux obtained from a heel stick of a 2-month old baby

    obtained from a heel stick of a 2-month old baby

  • 75

    Which of the following patient data best reflects the discrepancy seen when a person’s red cells demonstrate the acquired-B phenotype? Forward grouping Reverse grouping patient A B O patient B AB A patient C O B patient D B AB a A b B c C d D

    b B

  • 76

    Which of the following is characteristic of Tn polyagglutinable red cells? if group O, they may appear to have acquired a group A antigen they show strong reactions when the cells are enzyme-treated they react with Arachis hypogaea lectin the polyagglutination is a transient condition

    if group O, they may appear to have acquired a group A antigen

  • 77

    Mixed field agglutination encountered in ABO grouping with no history of transfusion would most likely be due to: a Bombay phenotype (Oh) b T activation c A3 red cells d_ positive indirect antiglobulin test

    c A3 red cells

  • 78

    Which of the following is a characteristic of polyagglutinable red cells? can be classified by reactivity with Ulex europaeus are agglutinated by most adult sera are always an acquired condition autocontrol is always positive

    are agglutinated by most adult sera

  • 79

    Consider the following ABO typing results: What is the most likely cause of this discrepancy? a Aj with anti-A; b cold alloantibody ¢ cold autoantibody d acquired-A phenomenon

    ¢ cold autoantibody

  • 80

    Consider the following ABO typing results: What should be done next? a test serum against a panel of group O cells b neutralization c perform serum type at 37°C d elution

    c perform serum type at 37°C

  • 81

    The following results were obtained on a patient’s blood sample during routine ABO and Rh testing: Cell testing: Serum testing: anti-A: 0 A1 cells: 4+ anti-B: 4+ B cells: 2+ anti-D: 0) autocontrol: 0 Select the course of action to resolve this problem: a draw a new blood sample from the patient and repeat all test procedures b test the patient’s serum with Ap cells and the patient’s red cells with anti-A, lectin ¢ repeat the ABO antigen grouping using 3x washed saline-suspended cells d perform antibody screening procedure at immediate spin using group O cells

    d perform antibody screening procedure at immediate spin using group O cells

  • 82

    Which of the following explains an ABO discrepancy caused by problems with the patient’s red blood cells? a an unexpected antibody b rouleaux c agammaglobulinemia d Tn activation

    d Tn activation

  • 83

    ‘The test for weak D is performed by incubating patient’s red cells with: a_ several different dilutions of anti-D serum b anti-D serum followed by washing and antiglobulin serum c anti-Du serum d antiglobulin serum

    b anti-D serum followed by washing and antiglobulin serum

  • 84

    Refer to the following data: Forward group: Reverse group: anti-A anti-B anti-A, lectin 4+ 0 4+ Which of the following antibody screen results would you expect with the ABO discrepancy seen above? a negative b positive with all screen cells at the 37°C phase c positive with all screen cells at the RT phase; autocontrol is negative d positive with all screen cells and the autocontrol cells at the RT phase

    c positive with all screen cells at the RT phase; autocontrol is negative

  • 85

    The following results were obtained when testing a sample from a 20-year-old, first-time blood donor: Forward group: Reverse group: anti-A anti-B A1 cells B cells 0) 0 0 3+ What is the most likely cause of this ABO discrepancy? a_ loss of antigen due to disease b acquired B c phenotype Oh “Bombay” d weak subgroup of A

    weak subgroup of A

  • 86

    A mother is Rh-negative and the father Rh-positive. Their baby is Rh-negative. It may be concluded that: the father is homozygous for D the mother is heterozygous for D the father is heterozygous for D at least 1 of the 3 Rh typings must be incorrect

    the father is heterozygous for D

  • 87

    Some blood group antibodies characteristically hemolyze appropriate red cells in the presence of: a complement b anticoagulants c preservatives d penicillin

    a complement

  • 88

    Review the following schematic diagram: PATIENT SERUM + REAGENT GROUP “O” CELLS INCUBATE —> READ FOR AGGLUTINATION WASH — ADD AHG — AGGLUTINATION OBSERVED ‘The next step would be to: a add “check cells” as a confirmatory measure b identify the cause of the agglutination c perform an elution technique d_ perform a direct antiglobulin test

    b identify the cause of the agglutination

  • 89

    The following results were obtained in pretransfusion testing: 37°C 1AT screening cell | 0 3+ screening cell Il 0 3+ autocontrol 0 3+ The most probable cause of these results is: a rouleaux b a warm autoantibody c acold autoantibody d multiple alloantibodies

    b a warm autoantibody

  • 90

    patient is typed as group O, Rh-positive and crossmatched with 6 units of blood. At the indirect antiglobulin (IAT) phase of testing, both antibody screening cells and 2 crossmatched units are incompatible. What is the most likely cause of the incompatibility? recipient alloantibody recipient autoantibody donors have positive DATs rouleaux

    recipient alloantibody

  • 91

    Refer to the following data: Which clinical condition is consistent with the lab results shown above? a cold hemagglutinin disease b warm autoimmune hemolytic anemia c penicillin-induced hemolytic anemia d delayed hemolytic transfusion reaction

    b warm autoimmune hemolytic anemia

  • 92

    A patient received 2 units of Red Blood Cells and had a delayed transfusion reaction. Pretransfusion antibody screening records indicate no agglutination except after the addition of IgG sensitized cells. Repeat testing of the pretransfusion specimen detected an antibody at the antiglobulin phase. What is the most likely explanation for the original results? red cells were overwashed centrifugation time was prolonged patient’s serum was omitted from the original testing antiglobulin reagent was neutralized

    patient’s serum was omitted from the original testing

  • 93

    At the indirect antiglobulin phase of testing, there is no agglutination between patient serum and screening cells. One of 3 donor units was incompatible. The most probable explanation for these findings is that the: a patient has an antibody directed against a high incidence antigen b patient has an antibody directed against a low incidence antigen c donor has an antibody directed against donor cells d donor has a positive antibody screen

    b patient has an antibody directed against a low incidence antigen

  • 94

    The major crossmatch will detect a(n): a group A patient mistyped as group O b unexpected red cell antibody in the donor unit c Rh-negative donor unit mislabeled as Rh-positive d recipient antibody directed against antigens on the donor red cells

    d recipient antibody directed against antigens on the donor red cells

  • 95

    A 42-year-old female is undergoing surgery tomorrow and her physician requests that 4 units of Red Blood Cells be crossmatched. The following results were obtained: What is the most likely cause of the incompatibility of donor 1? a single alloantibody b multiple alloantibodies c Rh incompatibilities d donor 1 has a positive DAT

    a single alloantibody

  • 96

    Which of the following would most likely be responsible for an incompatible antiglobulin crossmatch? a recipient’s red cells possess a low frequency antigen b anti-K antibody in donor serum ¢ recipient’s red cells are polyagglutinable d donor red cells have a positive direct antiglobulin test

    d donor red cells have a positive direct antiglobulin test

  • 97

    A reason why a patient’s crossmatch may be incompatible while the antibody screen is negative is: the patient has an antibody against a high-incidence antigen the incompatible donor unit has a positive direct antiglobulin test cold agglutinins are interfering in the crossmatch the patient's serum contains warm autoantibody

    the incompatible donor unit has a positive direct antiglobulin test

  • 98

    A blood specimen types as A, Rh-positive with a negative antibody screen. 6 units of group A, Rh-positive Red Blood Cells were crossmatched and 1 unit was incompatible in the antiglobulin phase. The same result was obtained when the test was repeated. Which should be done first? a repeat the ABO grouping on the incompatible unit using a more sensitive technique b test a panel of red cells that possesses low-incidence antigens c perform a direct antiglobulin test on the donor unit d_ obtain a new specimen and repeat the crossmatch

    c perform a direct antiglobulin test on the donor unit

  • 99

    During emergency situations when there is no time to determine ABO group and Rh type on a current sample for transfusion, the patient is known to be A, Rh-negative. The technologist should: refuse to release any blood until the patient’s sample has been typed release A Rh-negative Red Blood Cells release O Rh-negative Red Blood Cells release O Rh-positive Red Blood Cells

    release O Rh-negative Red Blood Cells

  • 100

    A 29-year-old male is hemorrhaging severely. He is AB, Rh-negative. 6 units of blood are required STAT. Of the following types available in the blood bank, which would be most preferable for crossmatch? a AB, Rh-positive b A, Rh-negative c A, Rh-positive dO, Rh-negative

    b A, Rh-negative

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    CC-2 SPECTROPHOTOMETRY

    CC-2 SPECTROPHOTOMETRY

    Yves Laure Pimentel · 100問 · 2年前

    CC-2 SPECTROPHOTOMETRY

    CC-2 SPECTROPHOTOMETRY

    100問 • 2年前
    Yves Laure Pimentel

    CC-3 ELECTROPHORESIS

    CC-3 ELECTROPHORESIS

    Yves Laure Pimentel · 41問 · 2年前

    CC-3 ELECTROPHORESIS

    CC-3 ELECTROPHORESIS

    41問 • 2年前
    Yves Laure Pimentel

    AUBF LAB SAFETY

    AUBF LAB SAFETY

    Yves Laure Pimentel · 87問 · 2年前

    AUBF LAB SAFETY

    AUBF LAB SAFETY

    87問 • 2年前
    Yves Laure Pimentel

    CSF 1

    CSF 1

    Yves Laure Pimentel · 100問 · 2年前

    CSF 1

    CSF 1

    100問 • 2年前
    Yves Laure Pimentel

    CSF 2

    CSF 2

    Yves Laure Pimentel · 82問 · 2年前

    CSF 2

    CSF 2

    82問 • 2年前
    Yves Laure Pimentel

    SEMEN 1

    SEMEN 1

    Yves Laure Pimentel · 100問 · 2年前

    SEMEN 1

    SEMEN 1

    100問 • 2年前
    Yves Laure Pimentel

    SEMEN 2

    SEMEN 2

    Yves Laure Pimentel · 7問 · 2年前

    SEMEN 2

    SEMEN 2

    7問 • 2年前
    Yves Laure Pimentel

    SYNOVIAL FLUID 1

    SYNOVIAL FLUID 1

    Yves Laure Pimentel · 100問 · 2年前

    SYNOVIAL FLUID 1

    SYNOVIAL FLUID 1

    100問 • 2年前
    Yves Laure Pimentel

    SYNOVIAL FLUID 2

    SYNOVIAL FLUID 2

    Yves Laure Pimentel · 6問 · 2年前

    SYNOVIAL FLUID 2

    SYNOVIAL FLUID 2

    6問 • 2年前
    Yves Laure Pimentel

    SEROUS FLUID

    SEROUS FLUID

    Yves Laure Pimentel · 25問 · 2年前

    SEROUS FLUID

    SEROUS FLUID

    25問 • 2年前
    Yves Laure Pimentel

    PLEURAL FLUID

    PLEURAL FLUID

    Yves Laure Pimentel · 44問 · 2年前

    PLEURAL FLUID

    PLEURAL FLUID

    44問 • 2年前
    Yves Laure Pimentel

    PERICARDIAL FLUID

    PERICARDIAL FLUID

    Yves Laure Pimentel · 18問 · 2年前

    PERICARDIAL FLUID

    PERICARDIAL FLUID

    18問 • 2年前
    Yves Laure Pimentel

    PERITONEAL FLUID/ ASCITIC FLUID

    PERITONEAL FLUID/ ASCITIC FLUID

    Yves Laure Pimentel · 30問 · 2年前

    PERITONEAL FLUID/ ASCITIC FLUID

    PERITONEAL FLUID/ ASCITIC FLUID

    30問 • 2年前
    Yves Laure Pimentel

    AMNIOTIC FLUID

    AMNIOTIC FLUID

    Yves Laure Pimentel · 92問 · 2年前

    AMNIOTIC FLUID

    AMNIOTIC FLUID

    92問 • 2年前
    Yves Laure Pimentel

    FECALYSIS

    FECALYSIS

    Yves Laure Pimentel · 80問 · 2年前

    FECALYSIS

    FECALYSIS

    80問 • 2年前
    Yves Laure Pimentel

    OTHER BODY FLUIDS

    OTHER BODY FLUIDS

    Yves Laure Pimentel · 89問 · 2年前

    OTHER BODY FLUIDS

    OTHER BODY FLUIDS

    89問 • 2年前
    Yves Laure Pimentel

    MTLBE- SUHO NOTES

    MTLBE- SUHO NOTES

    Yves Laure Pimentel · 86問 · 2年前

    MTLBE- SUHO NOTES

    MTLBE- SUHO NOTES

    86問 • 2年前
    Yves Laure Pimentel

    MTLBE..

    MTLBE..

    Yves Laure Pimentel · 35問 · 2年前

    MTLBE..

    MTLBE..

    35問 • 2年前
    Yves Laure Pimentel

    CC- CHROMATOGRAPHY

    CC- CHROMATOGRAPHY

    Yves Laure Pimentel · 19問 · 1年前

    CC- CHROMATOGRAPHY

    CC- CHROMATOGRAPHY

    19問 • 1年前
    Yves Laure Pimentel

    CC-OSMOMETRY

    CC-OSMOMETRY

    Yves Laure Pimentel · 14問 · 1年前

    CC-OSMOMETRY

    CC-OSMOMETRY

    14問 • 1年前
    Yves Laure Pimentel

    CC-ELECTROCHEMISTRY TECHNIQUES

    CC-ELECTROCHEMISTRY TECHNIQUES

    Yves Laure Pimentel · 43問 · 1年前

    CC-ELECTROCHEMISTRY TECHNIQUES

    CC-ELECTROCHEMISTRY TECHNIQUES

    43問 • 1年前
    Yves Laure Pimentel

    CC- CARBOHYDRATES

    CC- CARBOHYDRATES

    Yves Laure Pimentel · 49問 · 2年前

    CC- CARBOHYDRATES

    CC- CARBOHYDRATES

    49問 • 2年前
    Yves Laure Pimentel

    CC- DIABETES MELLITUS

    CC- DIABETES MELLITUS

    Yves Laure Pimentel · 97問 · 2年前

    CC- DIABETES MELLITUS

    CC- DIABETES MELLITUS

    97問 • 2年前
    Yves Laure Pimentel

    MAJOR LIPOPROTEINS

    MAJOR LIPOPROTEINS

    Yves Laure Pimentel · 57問 · 2年前

    MAJOR LIPOPROTEINS

    MAJOR LIPOPROTEINS

    57問 • 2年前
    Yves Laure Pimentel

    MINOR LIPOPROTEINS

    MINOR LIPOPROTEINS

    Yves Laure Pimentel · 63問 · 2年前

    MINOR LIPOPROTEINS

    MINOR LIPOPROTEINS

    63問 • 2年前
    Yves Laure Pimentel

    PROTEINS

    PROTEINS

    Yves Laure Pimentel · 37問 · 2年前

    PROTEINS

    PROTEINS

    37問 • 2年前
    Yves Laure Pimentel

    PLASMA PROTEINS 1

    PLASMA PROTEINS 1

    Yves Laure Pimentel · 91問 · 2年前

    PLASMA PROTEINS 1

    PLASMA PROTEINS 1

    91問 • 2年前
    Yves Laure Pimentel

    PLASMA PROTEINS 2 (ALPHA 2 REGION)

    PLASMA PROTEINS 2 (ALPHA 2 REGION)

    Yves Laure Pimentel · 98問 · 2年前

    PLASMA PROTEINS 2 (ALPHA 2 REGION)

    PLASMA PROTEINS 2 (ALPHA 2 REGION)

    98問 • 2年前
    Yves Laure Pimentel

    MISCELLANEOUS PROTEINS

    MISCELLANEOUS PROTEINS

    Yves Laure Pimentel · 61問 · 2年前

    MISCELLANEOUS PROTEINS

    MISCELLANEOUS PROTEINS

    61問 • 2年前
    Yves Laure Pimentel

    Liver Function Test 1

    Liver Function Test 1

    Yves Laure Pimentel · 100問 · 2年前

    Liver Function Test 1

    Liver Function Test 1

    100問 • 2年前
    Yves Laure Pimentel

    Liver Function Test 2

    Liver Function Test 2

    Yves Laure Pimentel · 96問 · 2年前

    Liver Function Test 2

    Liver Function Test 2

    96問 • 2年前
    Yves Laure Pimentel

    TUMOR MARKERS

    TUMOR MARKERS

    Yves Laure Pimentel · 33問 · 2年前

    TUMOR MARKERS

    TUMOR MARKERS

    33問 • 2年前
    Yves Laure Pimentel

    KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

    KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

    Yves Laure Pimentel · 41問 · 2年前

    KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

    KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

    41問 • 2年前
    Yves Laure Pimentel

    GLYCOGEN STORAGE DISEASES

    GLYCOGEN STORAGE DISEASES

    Yves Laure Pimentel · 17問 · 2年前

    GLYCOGEN STORAGE DISEASES

    GLYCOGEN STORAGE DISEASES

    17問 • 2年前
    Yves Laure Pimentel

    LIPID STORAGE DISEASES

    LIPID STORAGE DISEASES

    Yves Laure Pimentel · 14問 · 2年前

    LIPID STORAGE DISEASES

    LIPID STORAGE DISEASES

    14問 • 2年前
    Yves Laure Pimentel

    PROTEINS

    PROTEINS

    Yves Laure Pimentel · 71問 · 2年前

    PROTEINS

    PROTEINS

    71問 • 2年前
    Yves Laure Pimentel

    QUICK FIRE- ELECTRODES

    QUICK FIRE- ELECTRODES

    Yves Laure Pimentel · 7問 · 2年前

    QUICK FIRE- ELECTRODES

    QUICK FIRE- ELECTRODES

    7問 • 2年前
    Yves Laure Pimentel

    ELECTROLYTES

    ELECTROLYTES

    Yves Laure Pimentel · 10問 · 2年前

    ELECTROLYTES

    ELECTROLYTES

    10問 • 2年前
    Yves Laure Pimentel

    DRUGS

    DRUGS

    Yves Laure Pimentel · 27問 · 2年前

    DRUGS

    DRUGS

    27問 • 2年前
    Yves Laure Pimentel

    TOXIC AGENTS:

    TOXIC AGENTS:

    Yves Laure Pimentel · 12問 · 2年前

    TOXIC AGENTS:

    TOXIC AGENTS:

    12問 • 2年前
    Yves Laure Pimentel

    HEMATOLOGY 1 (HEMATOPOIESIS 1)

    HEMATOLOGY 1 (HEMATOPOIESIS 1)

    Yves Laure Pimentel · 100問 · 2年前

    HEMATOLOGY 1 (HEMATOPOIESIS 1)

    HEMATOLOGY 1 (HEMATOPOIESIS 1)

    100問 • 2年前
    Yves Laure Pimentel

    HEMATOLOGY (HEMATOPOIESIS 2)

    HEMATOLOGY (HEMATOPOIESIS 2)

    Yves Laure Pimentel · 29問 · 2年前

    HEMATOLOGY (HEMATOPOIESIS 2)

    HEMATOLOGY (HEMATOPOIESIS 2)

    29問 • 2年前
    Yves Laure Pimentel

    hema diseases

    hema diseases

    Yves Laure Pimentel · 25問 · 2年前

    hema diseases

    hema diseases

    25問 • 2年前
    Yves Laure Pimentel

    AML

    AML

    Yves Laure Pimentel · 43問 · 2年前

    AML

    AML

    43問 • 2年前
    Yves Laure Pimentel

    GLOBIN SYNTHESIS

    GLOBIN SYNTHESIS

    Yves Laure Pimentel · 71問 · 2年前

    GLOBIN SYNTHESIS

    GLOBIN SYNTHESIS

    71問 • 2年前
    Yves Laure Pimentel

    HEMATOLOGY REFERENCE RANGES

    HEMATOLOGY REFERENCE RANGES

    Yves Laure Pimentel · 31問 · 2年前

    HEMATOLOGY REFERENCE RANGES

    HEMATOLOGY REFERENCE RANGES

    31問 • 2年前
    Yves Laure Pimentel

    DISORDERS OF PRIMARY HEMOSTASIS

    DISORDERS OF PRIMARY HEMOSTASIS

    Yves Laure Pimentel · 34問 · 2年前

    DISORDERS OF PRIMARY HEMOSTASIS

    DISORDERS OF PRIMARY HEMOSTASIS

    34問 • 2年前
    Yves Laure Pimentel

    PLATELET DISORDERS

    PLATELET DISORDERS

    Yves Laure Pimentel · 37問 · 2年前

    PLATELET DISORDERS

    PLATELET DISORDERS

    37問 • 2年前
    Yves Laure Pimentel

    CHARACTERISTICS OF CLOTTING FACTORS

    CHARACTERISTICS OF CLOTTING FACTORS

    Yves Laure Pimentel · 100問 · 2年前

    CHARACTERISTICS OF CLOTTING FACTORS

    CHARACTERISTICS OF CLOTTING FACTORS

    100問 • 2年前
    Yves Laure Pimentel

    4. CLASSIFICATION OF MACROPHAGE

    4. CLASSIFICATION OF MACROPHAGE

    Yves Laure Pimentel · 12問 · 2年前

    4. CLASSIFICATION OF MACROPHAGE

    4. CLASSIFICATION OF MACROPHAGE

    12問 • 2年前
    Yves Laure Pimentel

    3. NATURAL OR INNATE IMMUNITY

    3. NATURAL OR INNATE IMMUNITY

    Yves Laure Pimentel · 39問 · 2年前

    3. NATURAL OR INNATE IMMUNITY

    3. NATURAL OR INNATE IMMUNITY

    39問 • 2年前
    Yves Laure Pimentel

    5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

    5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

    Yves Laure Pimentel · 55問 · 2年前

    5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

    5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

    55問 • 2年前
    Yves Laure Pimentel

    6. PHAGOCYTOSIS Chemotaxis

    6. PHAGOCYTOSIS Chemotaxis

    Yves Laure Pimentel · 37問 · 2年前

    6. PHAGOCYTOSIS Chemotaxis

    6. PHAGOCYTOSIS Chemotaxis

    37問 • 2年前
    Yves Laure Pimentel

    8. NATURE OF ANTIGEN

    8. NATURE OF ANTIGEN

    Yves Laure Pimentel · 44問 · 2年前

    8. NATURE OF ANTIGEN

    8. NATURE OF ANTIGEN

    44問 • 2年前
    Yves Laure Pimentel

    9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

    9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

    Yves Laure Pimentel · 50問 · 2年前

    9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

    9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

    50問 • 2年前
    Yves Laure Pimentel

    1. HISTORY

    1. HISTORY

    Yves Laure Pimentel · 69問 · 2年前

    1. HISTORY

    1. HISTORY

    69問 • 2年前
    Yves Laure Pimentel

    2. TYPES OF IMMUNITY

    2. TYPES OF IMMUNITY

    Yves Laure Pimentel · 38問 · 2年前

    2. TYPES OF IMMUNITY

    2. TYPES OF IMMUNITY

    38問 • 2年前
    Yves Laure Pimentel

    7. PHAGOCYTOSIS Engulfment and Digestion

    7. PHAGOCYTOSIS Engulfment and Digestion

    Yves Laure Pimentel · 21問 · 2年前

    7. PHAGOCYTOSIS Engulfment and Digestion

    7. PHAGOCYTOSIS Engulfment and Digestion

    21問 • 2年前
    Yves Laure Pimentel

    8. PHAGOCYTOSIS EXOCYTOSIS

    8. PHAGOCYTOSIS EXOCYTOSIS

    Yves Laure Pimentel · 15問 · 2年前

    8. PHAGOCYTOSIS EXOCYTOSIS

    8. PHAGOCYTOSIS EXOCYTOSIS

    15問 • 2年前
    Yves Laure Pimentel

    10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

    10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

    Yves Laure Pimentel · 32問 · 2年前

    10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

    10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

    32問 • 2年前
    Yves Laure Pimentel

    11. TRANSPLANTATION IMMUNOLOGY

    11. TRANSPLANTATION IMMUNOLOGY

    Yves Laure Pimentel · 30問 · 2年前

    11. TRANSPLANTATION IMMUNOLOGY

    11. TRANSPLANTATION IMMUNOLOGY

    30問 • 2年前
    Yves Laure Pimentel

    2. LYMPHOID ORGANS

    2. LYMPHOID ORGANS

    Yves Laure Pimentel · 38問 · 2年前

    2. LYMPHOID ORGANS

    2. LYMPHOID ORGANS

    38問 • 2年前
    Yves Laure Pimentel

    3. CLUSTER OF DIFFERENTIATION

    3. CLUSTER OF DIFFERENTIATION

    Yves Laure Pimentel · 48問 · 2年前

    3. CLUSTER OF DIFFERENTIATION

    3. CLUSTER OF DIFFERENTIATION

    48問 • 2年前
    Yves Laure Pimentel

    4. T-CELL DIFFERENTIATION

    4. T-CELL DIFFERENTIATION

    Yves Laure Pimentel · 35問 · 2年前

    4. T-CELL DIFFERENTIATION

    4. T-CELL DIFFERENTIATION

    35問 • 2年前
    Yves Laure Pimentel

    5. T CELL IMMUNODEFICIENCIES

    5. T CELL IMMUNODEFICIENCIES

    Yves Laure Pimentel · 18問 · 2年前

    5. T CELL IMMUNODEFICIENCIES

    5. T CELL IMMUNODEFICIENCIES

    18問 • 2年前
    Yves Laure Pimentel

    6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

    6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

    Yves Laure Pimentel · 44問 · 2年前

    6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

    6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

    44問 • 2年前
    Yves Laure Pimentel

    7. B CELL IMMUNODEFICIENCIES

    7. B CELL IMMUNODEFICIENCIES

    Yves Laure Pimentel · 23問 · 2年前

    7. B CELL IMMUNODEFICIENCIES

    7. B CELL IMMUNODEFICIENCIES

    23問 • 2年前
    Yves Laure Pimentel

    8. COMBINED T CELL AND B CELL DEFICIENCIES

    8. COMBINED T CELL AND B CELL DEFICIENCIES

    Yves Laure Pimentel · 34問 · 2年前

    8. COMBINED T CELL AND B CELL DEFICIENCIES

    8. COMBINED T CELL AND B CELL DEFICIENCIES

    34問 • 2年前
    Yves Laure Pimentel

    9. COMPARISON OF T AND B CELLS

    9. COMPARISON OF T AND B CELLS

    Yves Laure Pimentel · 12問 · 2年前

    9. COMPARISON OF T AND B CELLS

    9. COMPARISON OF T AND B CELLS

    12問 • 2年前
    Yves Laure Pimentel

    10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

    10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

    Yves Laure Pimentel · 16問 · 2年前

    10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

    10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

    16問 • 2年前
    Yves Laure Pimentel

    11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

    11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

    Yves Laure Pimentel · 15問 · 2年前

    11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

    11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

    15問 • 2年前
    Yves Laure Pimentel

    12. ANTIBODY

    12. ANTIBODY

    Yves Laure Pimentel · 79問 · 2年前

    12. ANTIBODY

    12. ANTIBODY

    79問 • 2年前
    Yves Laure Pimentel

    13. TYPES OF ANTIBODIES

    13. TYPES OF ANTIBODIES

    Yves Laure Pimentel · 97問 · 2年前

    13. TYPES OF ANTIBODIES

    13. TYPES OF ANTIBODIES

    97問 • 2年前
    Yves Laure Pimentel

    14. MONOCLONAL ANTIBODIES

    14. MONOCLONAL ANTIBODIES

    Yves Laure Pimentel · 11問 · 2年前

    14. MONOCLONAL ANTIBODIES

    14. MONOCLONAL ANTIBODIES

    11問 • 2年前
    Yves Laure Pimentel

    1. INTERLEUKINS

    1. INTERLEUKINS

    Yves Laure Pimentel · 23問 · 2年前

    1. INTERLEUKINS

    1. INTERLEUKINS

    23問 • 2年前
    Yves Laure Pimentel

    2. INTERFERONS

    2. INTERFERONS

    Yves Laure Pimentel · 28問 · 2年前

    2. INTERFERONS

    2. INTERFERONS

    28問 • 2年前
    Yves Laure Pimentel

    3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

    3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

    Yves Laure Pimentel · 8問 · 2年前

    3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

    3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

    8問 • 2年前
    Yves Laure Pimentel

    4. COMPLEMENT SYSTEM

    4. COMPLEMENT SYSTEM

    Yves Laure Pimentel · 19問 · 2年前

    4. COMPLEMENT SYSTEM

    4. COMPLEMENT SYSTEM

    19問 • 2年前
    Yves Laure Pimentel

    15. COMPLEMENT SYSTEM

    15. COMPLEMENT SYSTEM

    Yves Laure Pimentel · 76問 · 2年前

    15. COMPLEMENT SYSTEM

    15. COMPLEMENT SYSTEM

    76問 • 2年前
    Yves Laure Pimentel

    16. SYSTEM CONTROLS/COMPLEMENT REGULATION

    16. SYSTEM CONTROLS/COMPLEMENT REGULATION

    Yves Laure Pimentel · 21問 · 2年前

    16. SYSTEM CONTROLS/COMPLEMENT REGULATION

    16. SYSTEM CONTROLS/COMPLEMENT REGULATION

    21問 • 2年前
    Yves Laure Pimentel

    17. COMPLEMENT AND DISEASE STATES

    17. COMPLEMENT AND DISEASE STATES

    Yves Laure Pimentel · 29問 · 2年前

    17. COMPLEMENT AND DISEASE STATES

    17. COMPLEMENT AND DISEASE STATES

    29問 • 2年前
    Yves Laure Pimentel

    18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

    18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

    Yves Laure Pimentel · 19問 · 2年前

    18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

    18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

    19問 • 2年前
    Yves Laure Pimentel

    19. CYTOKINES

    19. CYTOKINES

    Yves Laure Pimentel · 22問 · 2年前

    19. CYTOKINES

    19. CYTOKINES

    22問 • 2年前
    Yves Laure Pimentel

    20. INTERLEUKINS

    20. INTERLEUKINS

    Yves Laure Pimentel · 24問 · 2年前

    20. INTERLEUKINS

    20. INTERLEUKINS

    24問 • 2年前
    Yves Laure Pimentel

    21. INTERFERONS, TNF, TGF, CHEMOKINE

    21. INTERFERONS, TNF, TGF, CHEMOKINE

    Yves Laure Pimentel · 21問 · 2年前

    21. INTERFERONS, TNF, TGF, CHEMOKINE

    21. INTERFERONS, TNF, TGF, CHEMOKINE

    21問 • 2年前
    Yves Laure Pimentel

    1. SERO

    1. SERO

    Yves Laure Pimentel · 54問 · 2年前

    1. SERO

    1. SERO

    54問 • 2年前
    Yves Laure Pimentel

    2. PRECIPITATION

    2. PRECIPITATION

    Yves Laure Pimentel · 38問 · 2年前

    2. PRECIPITATION

    2. PRECIPITATION

    38問 • 2年前
    Yves Laure Pimentel

    3. PASSIVE IMMUNODIFFUSION

    3. PASSIVE IMMUNODIFFUSION

    Yves Laure Pimentel · 17問 · 2年前

    3. PASSIVE IMMUNODIFFUSION

    3. PASSIVE IMMUNODIFFUSION

    17問 • 2年前
    Yves Laure Pimentel

    4. OUCHTERLONY

    4. OUCHTERLONY

    Yves Laure Pimentel · 15問 · 2年前

    4. OUCHTERLONY

    4. OUCHTERLONY

    15問 • 2年前
    Yves Laure Pimentel

    5. ELECTROPHORETIC TECHNIQUE

    5. ELECTROPHORETIC TECHNIQUE

    Yves Laure Pimentel · 9問 · 2年前

    5. ELECTROPHORETIC TECHNIQUE

    5. ELECTROPHORETIC TECHNIQUE

    9問 • 2年前
    Yves Laure Pimentel

    6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

    6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

    Yves Laure Pimentel · 11問 · 2年前

    6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

    6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

    11問 • 2年前
    Yves Laure Pimentel

    7. IMMUNOFIXATION ELECTROPHORESIS

    7. IMMUNOFIXATION ELECTROPHORESIS

    Yves Laure Pimentel · 29問 · 2年前

    7. IMMUNOFIXATION ELECTROPHORESIS

    7. IMMUNOFIXATION ELECTROPHORESIS

    29問 • 2年前
    Yves Laure Pimentel

    問題一覧

  • 1

    When the red cells of an individual fail to react with anti-U, they usually fail to react with: anti-M anti-Le anti-S anti-Py

    anti-S

  • 2

    Which of the following red cell antigens are found on glycophorin-A? M,N Le^a, Le^b S,s P1P1, Pk

    M,N

  • 3

    Paroxysmal cold hemoglobinuria (PCH) is associated with antibody specificity toward which of the following? a Kell system antigens b Duffy system antigens c P antigen d l antigen

    c P antigen

  • 4

    Which of the following is a characteristic of anti-i? a associated with warm autoimmune hemolytic anemia b found in the serum of patients with infectious mononucleosis c detected at lower temperatures in the serum of normal individuals d found only in the serum of group O individuals

    b found in the serum of patients with infectious mononucleosis

  • 5

    In a case of cold autoimmune hemolytic anemia, the patient’s serum would most likely react 4+ at immediate spin with: group A cells, B cells and O cells, but not his own cells cord cells but not his own or other adult cells all cells of a group O cell panel and his own cells only penicillin-treated panel cells, not his own cells

    all cells of a group O cell panel and his own cells

  • 6

    Cold agglutinin syndrome is associated with an antibody specificity toward which of the following? a Fy:3 b P c I d Rh:1

    c I

  • 7

    Which of the following is a characteristic of anti-i? often associated with hemolytic disease of the newborn reacts best at room temperature or 4°C reacts best at 37°C is usually IgG

    reacts best at room temperature or 4°C

  • 8

    The Kell (K1) antigen is: a absent from the red cells of neonates b strongly immunogenic c destroyed by enzymes d has a frequency of 50% in the random population

    b strongly immunogenic

  • 9

    In chronic granulomatous disease (CGD), granulocyte function is impaired. An association exists between this clinical condition and a depression of which of the following antigens? Rh P Kell Duffy

    Kell

  • 10

    The antibodies of the Kidd blood group system: react best by the indirect antiglobulin test are predominantly IgM often cause allergic transfusion reactions do not generally react with antigen-positive, enzyme-treated RBCs

    react best by the indirect antiglobulin test

  • 11

    Proteolytic enzyme treatment of red cells usually destroys which antigen? a Jk^a b E c Fy^a d k

    c Fy^a

  • 12

    Anti-Fy^a is: usually a cold-reactive agglutinin more reactive when tested with enzyme-treated red blood cells capable of causing hemolytic transfusion reactions often an autoagglutinin

    capable of causing hemolytic transfusion reactions

  • 13

    Resistance to malaria is best associated with which of the following blood groups? a Rh b I/i c P d Duffy

    d Duffy

  • 14

    What percent of group O donors would be compatible with a serum sample that contained anti-X and anti-Y if X antigen is present on red cells of 5 of 20 donors, and Y antigen is present on red cells of 1 of 10 donors? a 2.5 b 68 c 25.0 d 68.0

    d 68.0

  • 15

    How many Caucasians in a population of 100,000 will have the following combination of phenotypes? a 1 b 14 c 144 d 1,438

    d 1,438

  • 16

    What is the approximate probability of finding compatible blood among random Rh-positive units for a patient who has anti-c and anti-K? (Consider that 20% of Rh-positive donors lack c and 90% lack K) 1% 10% 18% 45%

    18%

  • 17

    A 25-year-old Caucasian woman, gravida 3, para 2, required 2 units of Red Blood Cells. The antibody screen was positive and the results of the antibody panel are shown below:

    d

  • 18

    Aman suffering from gastrointestinal bleeding has received 20 units of Red Blood Cells in the last 24 hours and is still oozing post-operatively. The following results were obtained: What blood product should be administered? a Fresh Frozen Plasma b Red Blood Cells c Factor VIII Concentrate d Platelets

    a Fresh Frozen Plasma

  • 19

    Transfusion of which of the following is needed to help correct hypofibrinogenemia due to DIC? Whole Blood Fresh Frozen Plasma Cryoprecipitated AHF Platelets

    Cryoprecipitated AHF

  • 20

    blood component used in the treatment of hemophilia A is: Factor VIII Concentrate Fresh Frozen Plasma Platelets Whole Blood

    Factor VIII Concentrate

  • 21

    Which of the following blood components is most appropriate to transfuse to an 8-year-old male hemophiliac who is about to undergo minor surgery? Cryoprecipitated AHF Red Blood Cells Platelets Factor VIII Concentrate

    Factor VIII Concentrate

  • 22

    A unit of Fresh Frozen Plasma was inadvertently thawed and then immediately refrigerated at 4°C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement for: a_ all coagulation factors b Factor V ec Factor VIII d Factor IX

    d Factor IX

  • 23

    A newborn demonstrates petechiae, ecchymosis and mucosal bleeding. The preferred blood component for this infant would be: a Red Blood Cells b Fresh Frozen Plasma c Platelets d Cryoprecipitated AHF

    c Platelets

  • 24

    Which of the following would be the best source of Platelets for transfusion in the case of alloimmune neonatal thrombocytopenia? a father b mother c pooled platelet-rich plasma d polycythemic donor

    b mother

  • 25

    An obstetrical patient has had 3 previous pregnancies. Her first baby was healthy, the second was jaundiced at birth and required an exchange transfusion, while the third was stillborn. Which of the following is the most likely cause? a ABO incompatibility b immune deficiency disease c congenital spherocytic anemia d Rh incompatibility

    d Rh incompatibility

  • 26

    A specimen of cord blood is submitted to the transfusion service for routine testing. The following results are obtained: It is known that the father is group B, with the genotype of cde/cde. Of the following 4 antibodies, which 1 is the most likely cause of the positive direct antiglobulin test? a anti-A b anti-D ¢ anti-c d anti-C

    ¢ anti-c

  • 27

    ABO-hemolytic disease of the newborn: a usually requires an exchange transfusion b most often occurs in first born children c frequently results in stillbirth d is usually seen only in the newborn of group O mothers

    d is usually seen only in the newborn of group O mothers

  • 28

    Which of the following antigens is most likely to be involved in hemolytic disease of the newborn? a Le^a b P1 c M d Kell

    d Kell

  • 29

    ABO hemolytic disease of the fetus and newborn (HDFN) differs from Rh HDFN in that: a Rh HDFN is clinically more severe than ABO HDFN b the direct antiglobulin test is weaker in Rh HDFN than ABO c RhHODEN occurs in the first pregnancy d_ the mother’s antibody screen is positive in ABO HDN

    a Rh HDFN is clinically more severe than ABO HDFN

  • 30

    The following results were obtained: Which of the following is the most probable explanation for these results? a ABO hemolytic disease of the fetus and newborn b Rh hemolytic disease of the fetus and newborn; infant has received intrauterine transfusions c Rhhemolytic disease of the fetus and newborn, infant has a false-negative Rh typing d large fetomaternal hemorrhage

    c Rhhemolytic disease of the fetus and newborn, infant has a false-negative Rh typing

  • 31

    A group A, Rh-positive infant of a group O, Rh-positive mother has a weakly positive direct antiglobulin test and a moderately elevated bilirubin 12 hours after birth. The most likely cause is: a ABO incompatibility b Rh incompatibility c blood group incompatibility due to an antibody to a low frequency antigen d neonatal jaundice not associated with blood group

    a ABO incompatibility

  • 32

    In suspected cases of hemolytic disease of the newborn, what significant information can be obtained from the baby’s blood smear? a estimation of WBC, RBC, and platelet counts b marked increase in immature neutrophils (shift to the left) c a differential to estimate the absolute number of lymphocytes present d_ determination of the presence of spherocytes

    d_ determination of the presence of spherocytes

  • 33

    The Liley method of predicting the severity of hemolytic disease of the newborn is based on the amniotic fluid: a_ bilirubin concentration by standard methods b change in optical density measured at 450 nm ¢ Rh determination d ratio of lecithin to sphingomyelin

    b change in optical density measured at 450 nm

  • 34

    These laboratory results were obtained on maternal and cord blood samples: mother: A- baby: AB+, DAT: 3+ cord hemoglobin: 10 g/dL (100 g/L) Does the baby have HDN? a no, as indicated by the cord hemoglobin b yes, although the cord hemoglobin is normal, the DAT indicates HDN ¢ yes, the DAT and cord hemoglobin level both support HDN d_ no, a diagnosis of HDN cannot be established without cord bilirubin levels

    ¢ yes, the DAT and cord hemoglobin level both support HDN

  • 35

    The main purpose of performing antibody titers on serum from prenatal immunized women is to: a determine the identity of the antibody b identify candidates for amniocentesis or percutaneous umbilical blood sampling c decide if the baby needs an intrauterine transfusion d_ determine if early induction of labor is indicated

    b identify candidates for amniocentesis or percutaneous umbilical blood sampling

  • 36

    Which unit should be selected for exchange transfusion if the newborn is group A, Rh-positive and the mother is group A, Rh-positive with anti-c? a A, CDe/CDe b A, cDE/cDE c O,cde/cde d A, cde/cde

    a A, CDe/CDe

  • 37

    A mother is group A, with anti-D in her serum. What would be the preferred blood product if an intrauterine transfusion is indicated? a O, Rh-negative Red Blood Cells b O, Rh-negative Red Blood Cells, Irradiated c A, Rh-negative Red Blood Cells d A, Rh-negative Red Blood Cells, Irradiated

    b O, Rh-negative Red Blood Cells, Irradiated

  • 38

    Laboratory studies of maternal and cord blood yield the following results: Maternal blood Cord blood O, Rh-negative B, Rh-positive anti-E in serum DAT = 2+ anti-E in eluate If exchange transfusion is necessary, the best choice of blood is: a _ B, Rh-negative, E+ b_ B, Rh-positive, E+ c_ O, Rh-negative, Ed O, Rh-positive, E

    d O, Rh-positive, E

  • 39

    A blood specimen from a pregnant woman is found to be group B, Rh-negative and the serum contains anti-D with a titer of 512. What would be the most appropriate type of blood to have available for a possible exchange transfusion for her infant? O, Rh-negative O, Rh-pasitive B, Rh-negative B, Rh-positive

    O, Rh-negative

  • 40

    Blood selected for exchange transfusion must: a_ lack red blood cell antigens corresponding to maternal antibodies b be <3 days old c be the same Rh type as the baby d be ABO compatible with the father

    a_ lack red blood cell antigens corresponding to maternal antibodies

  • 41

    When the main objective of an exchange transfusion is to remove the infant’s antibody-sensitized red blood cells and to control hyperbilirubinemia, the blood product of choice is ABO compatible: Fresh Whole Blood Red Blood Cells (RBC) washed RBC suspended in Fresh Frozen Plasma heparinized Red Blood Cells

    RBC suspended in Fresh Frozen Plasma

  • 42

    To prevent graft-vs-host disease, Red Blood Cells prepared for infants who have received intrauterine transfusions should be: a saline-washed b irradiated c frozen and deglycerolized d group- and Rh-compatible with the mother

    b irradiated

  • 43

    Which of the following is the preferred specimen for the initial compatibility testing in exchange transfusion therapy? a maternal serum b eluate prepared from infant’s red blood cells ¢ paternal serum d infant’s postexchange serum

    a maternal serum

  • 44

    Rh-Immune Globulin is requested for an Rh-negative mother who has the following results: What is the most likely explanation? a mother is a genetic weak D b mother had a fetomaternal hemorrhage of D+ cells ¢« mother’s red cells are coated weakly with IgG d anti-D reagent is contaminated with an atypical antibody

    b mother had a fetomaternal hemorrhage of D+ cells

  • 45

    The following results are seen on a maternal postpartum sample: The most appropriate course of action is to: a report the mother as Rh-negative b report the mother as Rh-positive ¢ perform an elution on mother’s RBCs d investigate for a fetomaternal hemorrhage

    d investigate for a fetomaternal hemorrhage

  • 46

    What is the most appropriate interpretation for the laboratory data given below when an Rh-negative woman has an Rh-positive child? Rosette fetal screen using enzyme-treated D+ cells mother’s sample: 1 rosette/3 fields positive control: 5 rosettes/3 fields negative control: no rosettes observed Mother is not a candidate for Rhlg mother needs 1 vial of Rhlg mother needs 2 vials of Rhlg the fetal-maternal hemorrhage needs to be quantitated

    Mother is not a candidate for Rhlg

  • 47

    Refer to the following information: What is the best interpretation for the laboratory data given above? a mother is Rh-positive b mother is weak D+ ¢ mother has had a fetal-maternal hemorrhage d mother has a positive DAT

    ¢ mother has had a fetal-maternal hemorrhage

  • 48

    a weakly reactive anti-D is detected in a postpartum specimen from an Rh-negative woman. During her prenatal period, all antibody screening tests were negative. These findings indicate: a_ that she is a candidate for Rh immune globulin b that she is not a candidate for Rh immune globulin c a need for further investigation to determine candidacy for Rh immune globulin d_ the presence of Rh-positive cells in her circulation

    c a need for further investigation to determine candidacy for Rh immune globulin

  • 49

    Th e results of a Kleihauer-Betke stain indicate a fetomaternal hemorrhage of 35 mL of whole blood. How many vials of Rh immune globulin would be required? a 1 b 2 c 3 d 4

    b 2

  • 50

    fetomaternal hemorrhage of 35 mL of fetal Rh-positive packed RBCs has been detected in an Rh-negative woman. How many vials of Rh immune globulin should be given? 0 1 2 3

    3

  • 51

    Criteria determining Rh immune globulin eligibility include: mother is Rh-positive infant is Rh-negative mother has not been previously immunized to the D antigen infant has a positive direct antiglobulin test

    mother has not been previously immunized to the D antigen

  • 52

    hile performing routine postpartum testing for an Rh immune globulin (RhIG) candidate, a weakly positive antibody screening test was found. Anti-D was identified. This antibody is most likely the result of: a massive fetomaternal hemorrhage occurring at the time of this delivery b antenatal administration of Rh immune globulin at 28 weeks gestation ¢ contamination of the blood sample with Wharton jelly d_ mother having a positive direct antiglobulin test

    b antenatal administration of Rh immune globulin at 28 weeks gestation

  • 53

    Rh immune globulin administration would not be indicated in an Rh-negative woman who has a(n): first trimester abortion husband who is Rh-positive anti-D titer of 1:4,096 positive direct antiglobulin test

    anti-D titer of 1:4,096

  • 54

    A Kleihauer-Betke stain of a postpartum blood film revealed 0.3% fetal cells. What is the estimated volume (mL) of the fetomaternal hemorrhage expressed as whole blood? 5 15 25 35

    25

  • 55

    Based upon Kleihauer-Betke test results, which of the following formulas is used to determine the volume of fetomaternal hemorrhage expressed in mL of whole blood? % of fetal cells present x 30 % of fetal cells present x 50 % of maternal cells present x 30 % of maternal cells present x 50

    % of fetal cells present x 50

  • 56

    An acid elution stain was made using a 1-hour post-delivery maternal blood sample. Out of 2,000 cells that were counted, 30 of them appeared to contain fetal hemoglobin. It is the policy of the medical center to add 1 vial of Rh immune globulin to the calculated dose when the estimated volume of the hemorrhage exceeds 20 mL of whole blood. Calculate the number of vials of Rh immune globulin that would be indicated under these circumstances. a 2 b 3 c 4 d 5

    c 4

  • 57

    The rosette test will detect a fetomaternal hemorrhage (FMH) as small as: a 10mL b 15mL c 20mL d 30 mL

    a 10mL

  • 58

    A10 mL fetal maternal hemorrhage in an Rh-negative woman who delivered an Rh-positive baby MLS ony means that the: mother’s antibody screen will be positive for anti-D rosette test will be positive mother is not a candidate for Rh immune globulin mother should receive 2 doses of Rh immune globulin

    rosette test will be positive

  • 59

    Mixed leukocyte culture (MLC) is a biclogical assay for detecting which of the following? HLA-A antigens HLA-B antigens HLA-D antigens immunoglobulins

    HLA-D antigens

  • 60

    A 40-year-old man with autoimmune hemolytic anemia due to anti-E has a hemoglobin level of 10.8 g/dL (108 g/L). This patient will most likely be treated with: a Whole Blood b Red Blood Cells c Fresh Frozen Plasma d no transfusion

    d no transfusion

  • 61

    patient in the immediate post bone marrow transplant period has a hematocrit of 21%. The red cell product of choice for this patient would be: packed saline washed microaggregate filtered irradiated

    irradiated

  • 62

    HLA antigen typing is important in screening for: ABO incompatibility a kidney donor Rh incompatibility a blood donor

    a kidney donor

  • 63

    DR antigens in the HLA system are: expressed on platelets expressed on granulocytes significant in organ transplantation not detectable in the lymphocytotoxicity test

    expressed on platelets

  • 64

    Anti-E is identified in a panel at the antiglobulin phase. When check cells are added to the tubes, no agglutination is seen. The most appropriate course of action would be to: quality control the AHG reagent and check cells and repeat the panel open a new vial of check cells for subsequent testing that day open a new vial of AHG for subsequent testing that day record the check cell reactions and report the antibody panel result

    quality control the AHG reagent and check cells and repeat the panel

  • 65

    A serological centrifuge is recalibrated for ABO testing after major repairs. Given the data above, the centrifuge time for this machine should be: a 15 seconds b 20 seconds c 25 seconds d 30 seconds

    b 20 seconds

  • 66

    Which of the following represents an acceptably identified patient for sample collection and transfusion? a a handwritten band with patient’s name and hospital identification number is affixed to the patient's leg b_ the addressographed hospital band is taped to the patient’s bed ¢ anunbanded patient responds positively when his name is called d_ the chart transported with the patient contains his armband not yet attached

    a a handwritten band with patient’s name and hospital identification number is affixed to the patient's leg

  • 67

    Samples from the same patient were received on 2 consecutive days. Test results are summarized below: How should the request for crossmatch be handled? a crossmatch A, Rh-positive units with sample from day 1 b crossmatch B, Rh-positive units with sample from day 2 ¢ crossmatch AB, Rh-positive units with both samples d collect anew sample and repeat the tests

    d collect anew sample and repeat the tests

  • 68

    The following test results are noted for a unit of blood labeled group A, Rh-negative: Cells tested with: anti-A anti-B anti-D 4+ 0 3+ What should be done next? a transfuse as a group A, Rh-negative b transfuse as a group A, Rh-positive ¢ notify the collecting facility d discard the unit

    ¢ notify the collecting facility

  • 69

    What information is essential on patient blood sample labels drawn for compatibility testing? a_ biohazard sticker for AIDS patients b patient’s room number ¢ unique patient medical number d_ phiebotomist initials

    ¢ unique patient medical number

  • 70

    Granulocytes for transfusion should: a_ be administered through a microaggregate filter b be ABO compatible with the recipient’s serum c be infused within 72 hours of collection d never be transfused to patients with a history of febrile transfusion reactions

    b be ABO compatible with the recipient’s serum

  • 71

    A neonate will be transfused for the first time with group O Red Blood Cells. Which of the following is appropriate compatibility testing? crossmatch with mother’s serum crossmatch with baby’s serum no crossmatch is necessary if initial plasma screening is negative no screening or crossmatching is necessary for neonates

    no crossmatch is necessary if initial plasma screening is negative

  • 72

    A group B, Rh-negative patient has a positive DAT. Which of the following situations would occur? a_ all major crossmatches would be incompatible b the weak D test and control would be positive c_ the antibody screening test would be positive d_ the forward and reverse ABO groupings would not agree

    b the weak D test and control would be positive

  • 73

    ‘The following reactions were obtained: Cells tested with: Serum tested with: anti-A anti-B anti-A,B A1 cells B cells 4+ 3+ 4+ 1+ 4+ The technologist washed the patient’s cells with saline, and repeated the forward typing. A saline replacement technique was used with the reverse typing. The following results were obtained: Cells tested with: Serum tested with: anti-A anti-B anti-A,B A1 cells Bcells 4+ 0 4+ 0 A+ The results are consistent with: a acquired immunodeficiency disease b Bruton agammaglobulinemia c multiple myeloma d acquired “B” antigen

    c multiple myeloma

  • 74

    What is the most likely cause of the following ABO discrepancy? Patient's cells vs: Patient’s serum vs: anti-A anti- B A1 cells B cells 0 0 0 0 recent transfusion with group O blood antigen depression due to leukemia false-negative cell typing due to rouleaux obtained from a heel stick of a 2-month old baby

    obtained from a heel stick of a 2-month old baby

  • 75

    Which of the following patient data best reflects the discrepancy seen when a person’s red cells demonstrate the acquired-B phenotype? Forward grouping Reverse grouping patient A B O patient B AB A patient C O B patient D B AB a A b B c C d D

    b B

  • 76

    Which of the following is characteristic of Tn polyagglutinable red cells? if group O, they may appear to have acquired a group A antigen they show strong reactions when the cells are enzyme-treated they react with Arachis hypogaea lectin the polyagglutination is a transient condition

    if group O, they may appear to have acquired a group A antigen

  • 77

    Mixed field agglutination encountered in ABO grouping with no history of transfusion would most likely be due to: a Bombay phenotype (Oh) b T activation c A3 red cells d_ positive indirect antiglobulin test

    c A3 red cells

  • 78

    Which of the following is a characteristic of polyagglutinable red cells? can be classified by reactivity with Ulex europaeus are agglutinated by most adult sera are always an acquired condition autocontrol is always positive

    are agglutinated by most adult sera

  • 79

    Consider the following ABO typing results: What is the most likely cause of this discrepancy? a Aj with anti-A; b cold alloantibody ¢ cold autoantibody d acquired-A phenomenon

    ¢ cold autoantibody

  • 80

    Consider the following ABO typing results: What should be done next? a test serum against a panel of group O cells b neutralization c perform serum type at 37°C d elution

    c perform serum type at 37°C

  • 81

    The following results were obtained on a patient’s blood sample during routine ABO and Rh testing: Cell testing: Serum testing: anti-A: 0 A1 cells: 4+ anti-B: 4+ B cells: 2+ anti-D: 0) autocontrol: 0 Select the course of action to resolve this problem: a draw a new blood sample from the patient and repeat all test procedures b test the patient’s serum with Ap cells and the patient’s red cells with anti-A, lectin ¢ repeat the ABO antigen grouping using 3x washed saline-suspended cells d perform antibody screening procedure at immediate spin using group O cells

    d perform antibody screening procedure at immediate spin using group O cells

  • 82

    Which of the following explains an ABO discrepancy caused by problems with the patient’s red blood cells? a an unexpected antibody b rouleaux c agammaglobulinemia d Tn activation

    d Tn activation

  • 83

    ‘The test for weak D is performed by incubating patient’s red cells with: a_ several different dilutions of anti-D serum b anti-D serum followed by washing and antiglobulin serum c anti-Du serum d antiglobulin serum

    b anti-D serum followed by washing and antiglobulin serum

  • 84

    Refer to the following data: Forward group: Reverse group: anti-A anti-B anti-A, lectin 4+ 0 4+ Which of the following antibody screen results would you expect with the ABO discrepancy seen above? a negative b positive with all screen cells at the 37°C phase c positive with all screen cells at the RT phase; autocontrol is negative d positive with all screen cells and the autocontrol cells at the RT phase

    c positive with all screen cells at the RT phase; autocontrol is negative

  • 85

    The following results were obtained when testing a sample from a 20-year-old, first-time blood donor: Forward group: Reverse group: anti-A anti-B A1 cells B cells 0) 0 0 3+ What is the most likely cause of this ABO discrepancy? a_ loss of antigen due to disease b acquired B c phenotype Oh “Bombay” d weak subgroup of A

    weak subgroup of A

  • 86

    A mother is Rh-negative and the father Rh-positive. Their baby is Rh-negative. It may be concluded that: the father is homozygous for D the mother is heterozygous for D the father is heterozygous for D at least 1 of the 3 Rh typings must be incorrect

    the father is heterozygous for D

  • 87

    Some blood group antibodies characteristically hemolyze appropriate red cells in the presence of: a complement b anticoagulants c preservatives d penicillin

    a complement

  • 88

    Review the following schematic diagram: PATIENT SERUM + REAGENT GROUP “O” CELLS INCUBATE —> READ FOR AGGLUTINATION WASH — ADD AHG — AGGLUTINATION OBSERVED ‘The next step would be to: a add “check cells” as a confirmatory measure b identify the cause of the agglutination c perform an elution technique d_ perform a direct antiglobulin test

    b identify the cause of the agglutination

  • 89

    The following results were obtained in pretransfusion testing: 37°C 1AT screening cell | 0 3+ screening cell Il 0 3+ autocontrol 0 3+ The most probable cause of these results is: a rouleaux b a warm autoantibody c acold autoantibody d multiple alloantibodies

    b a warm autoantibody

  • 90

    patient is typed as group O, Rh-positive and crossmatched with 6 units of blood. At the indirect antiglobulin (IAT) phase of testing, both antibody screening cells and 2 crossmatched units are incompatible. What is the most likely cause of the incompatibility? recipient alloantibody recipient autoantibody donors have positive DATs rouleaux

    recipient alloantibody

  • 91

    Refer to the following data: Which clinical condition is consistent with the lab results shown above? a cold hemagglutinin disease b warm autoimmune hemolytic anemia c penicillin-induced hemolytic anemia d delayed hemolytic transfusion reaction

    b warm autoimmune hemolytic anemia

  • 92

    A patient received 2 units of Red Blood Cells and had a delayed transfusion reaction. Pretransfusion antibody screening records indicate no agglutination except after the addition of IgG sensitized cells. Repeat testing of the pretransfusion specimen detected an antibody at the antiglobulin phase. What is the most likely explanation for the original results? red cells were overwashed centrifugation time was prolonged patient’s serum was omitted from the original testing antiglobulin reagent was neutralized

    patient’s serum was omitted from the original testing

  • 93

    At the indirect antiglobulin phase of testing, there is no agglutination between patient serum and screening cells. One of 3 donor units was incompatible. The most probable explanation for these findings is that the: a patient has an antibody directed against a high incidence antigen b patient has an antibody directed against a low incidence antigen c donor has an antibody directed against donor cells d donor has a positive antibody screen

    b patient has an antibody directed against a low incidence antigen

  • 94

    The major crossmatch will detect a(n): a group A patient mistyped as group O b unexpected red cell antibody in the donor unit c Rh-negative donor unit mislabeled as Rh-positive d recipient antibody directed against antigens on the donor red cells

    d recipient antibody directed against antigens on the donor red cells

  • 95

    A 42-year-old female is undergoing surgery tomorrow and her physician requests that 4 units of Red Blood Cells be crossmatched. The following results were obtained: What is the most likely cause of the incompatibility of donor 1? a single alloantibody b multiple alloantibodies c Rh incompatibilities d donor 1 has a positive DAT

    a single alloantibody

  • 96

    Which of the following would most likely be responsible for an incompatible antiglobulin crossmatch? a recipient’s red cells possess a low frequency antigen b anti-K antibody in donor serum ¢ recipient’s red cells are polyagglutinable d donor red cells have a positive direct antiglobulin test

    d donor red cells have a positive direct antiglobulin test

  • 97

    A reason why a patient’s crossmatch may be incompatible while the antibody screen is negative is: the patient has an antibody against a high-incidence antigen the incompatible donor unit has a positive direct antiglobulin test cold agglutinins are interfering in the crossmatch the patient's serum contains warm autoantibody

    the incompatible donor unit has a positive direct antiglobulin test

  • 98

    A blood specimen types as A, Rh-positive with a negative antibody screen. 6 units of group A, Rh-positive Red Blood Cells were crossmatched and 1 unit was incompatible in the antiglobulin phase. The same result was obtained when the test was repeated. Which should be done first? a repeat the ABO grouping on the incompatible unit using a more sensitive technique b test a panel of red cells that possesses low-incidence antigens c perform a direct antiglobulin test on the donor unit d_ obtain a new specimen and repeat the crossmatch

    c perform a direct antiglobulin test on the donor unit

  • 99

    During emergency situations when there is no time to determine ABO group and Rh type on a current sample for transfusion, the patient is known to be A, Rh-negative. The technologist should: refuse to release any blood until the patient’s sample has been typed release A Rh-negative Red Blood Cells release O Rh-negative Red Blood Cells release O Rh-positive Red Blood Cells

    release O Rh-negative Red Blood Cells

  • 100

    A 29-year-old male is hemorrhaging severely. He is AB, Rh-negative. 6 units of blood are required STAT. Of the following types available in the blood bank, which would be most preferable for crossmatch? a AB, Rh-positive b A, Rh-negative c A, Rh-positive dO, Rh-negative

    b A, Rh-negative