medical faculty in Paris

Describes application of chemistry to pathology and therapeutics

Predicted that chemical analysis of body fluids altered by disease and has important role in investigating pathogenesis

Did not believe chemical studies were relevant to clinical medicine.

Advised “ In acquiring too extensive a knowledge of chemistry”extensive a knowledge of chemistry”

stressed the practical diagnostic value of chemistry

average medical student or average practitioner had barely a nodding acquaintance with chemistry and could not use a microscope

he characterized him as “the complete clinical chemist”

wrote the first book in English to carry the title “Clinical Chemistry”

Clinical application of blood chemistry determinations was especially abused.

developed the volumetric gas measuring apparatus for determining carbon dioxide concentration, the first instrument designed specifically for the clinical chemistry labor

he helped to develop methods for testing glucose and total serum protein in body fluids

One physician in ____ described the approach to patients as “a five-minute history followed by a five-day barrage of special tests in the hope that the diagnostic rabbit may suddenly emerge from the laboratory hat …

Supernatant of anticoagulated blood

Supertanant of clotted blood

Also known as clotting

the most common biological fluid collected for clinical laboratory testing

as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot

The usual values for a healthy population

Also known as the normal range

biologically important substances in the body fluids, the one being measured

PATHOGENESIS: “pathos”

PATHOGENESIS: “genesis”

Study and diagnosis of disease (dx)

Process by which are disease or disorders develops

Also known as the treatment (tx)

Test that doctors gives info about the body fluids balance, levels of electrolytes, levels of kidney and liver markers

Outcome or course of disease

Developed early blood tests, including those for createnine using what method?

he helped to develop methods for testing glucose and total serum protein in body fluid

the most common problem cited by doctors was the large number and unintelligent use of laboratory tests ordered in hospitals as a matter of course, without apparent relevance to the condition for which the patient was admitted or understanding of the test’s meaning or limitations

published the first reference ranges for uric acid, nonprotein nitrogen (NPN), and protein in blood

For clinical chemistry includes, not only the development of methods, but study of all the phenomena of the body’s normal chemical processes, and of the alterations that they undergo in disease.

In what year he characterized him as “the complete clinical chemist”