暗記メーカー
ログイン
Biotech immune tech
  • Laxamana, Ivan Christopher L.

  • 問題数 72 • 10/4/2023

    記憶度

    完璧

    10

    覚えた

    27

    うろ覚え

    0

    苦手

    0

    未解答

    0

    アカウント登録して、解答結果を保存しよう

    問題一覧

  • 1

    is a key player of the adaptive immune response that is responsible for humoral immunity in mammals.

    b cells

  • 2

    The surfaces of bacteria and viruses are coated with _________ and _________ that are recognized by antibodies in the host organism.

    glycoprotein , lipoprotein

  • 3

    The surfaces of bacteria and viruses are coated with glycoprotein and lipoproteins that are recognized by _______ in the host organism.

    antibodies

  • 4

    It is a toxin or other foreign substance which induces an immune response in the body

    antigen

  • 5

    It is a protein produced by the body's immune system when it detects harmful substances, called antigens.

    antibodies

  • 6

    The immune system mediates immunity to various infectious agents through specific immunity or _________ immunity •

    acquired

  • 7

    Antibodies only recognize a small _______ or dimple on the surface of a protein.

    ridge

  • 8

    The region of the antigen that binds to the antibody is called an

    epitope

  • 9

    are encoded by a family of genes that are different for every person.

    mhc receptors

  • 10

    b cells originate in the

    bone marrow

  • 11

    The “B” in B-cells came from the word _____

    bursa

  • 12

    responsible for producing antibodies

    b cells

  • 13

    Coats bacteria and causes them to be unaffected by antibiotics

    biofilm

  • 14

    other term for antibody

    immunoglobulin

  • 15

    It is a glycoprotein that is made in response to antigen

    immunoglobulin

  • 16

    binding site of the antigen and can be altered depending on the type of antigen

    variable region

  • 17

    A region in antibody where it doesn’t undergo any changes

    constant region

  • 18

    2 types of specific or acquired immunity

    humoral response, cellular response

  • 19

    It is a response whose responsible are the b cells. Antibodies produced by the b cells do not kill the cell, but only bind or attack the invaders outside the cell.

    humoral response

  • 20

    It is a response whose responsible are the T cells.

    cellular response

  • 21

    aka the killer cells. They kill the infected cells which lead to cell death

    cytotoxic t cells

  • 22

    Stimulate B-cell to produce more antbodies. Help develop the cytotoxio cell.

    helper t cells

  • 23

    It is a cell whose function is to engulf foreign substances

    macrophage

  • 24

    Responsible for activating helper t cells

    mhc class 1

  • 25

    mhc stands for

    major histocompatibility complex

  • 26

    Responsible for activating cytotoxic t cells

    mhc class 2

  • 27

    3 segments in human

    variable, diversity, joining

  • 28

    Attachment process of antibody to the antigen

    preparation, recognition, response, refinement, memory

  • 29

    advantages of surface antigen

    recognition, cell evasion, identification, biofilm formation

  • 30

    The great diversity of antibodies - GENE SHUFFLING

    gene segments, rearrangement, combinatorial diversity, junctional diversity, somatic hypermutation, selection

  • 31

    consist of two identical heavy chains

    heavy chains

  • 32

    It contributes to the antibody structure’s overall stability

    heavy chains

  • 33

    2 regions of each heavy chains

    constant region (ch), variable region (vh)

  • 34

    have two identical light chains that are smaller that heavy chains

    light chains

  • 35

    2 regions of each light chains

    constant region (cl), variable region (vl)

  • 36

    The tip of each arm of the Y-shaped antibody molecule contains an _____ aka FAB

    antigen-binding site

  • 37

    FAB stands for

    fragment antigen binding

  • 38

    It is a antibody structure formed by both light and heavy chains

    antigen-binding site

  • 39

    The stem of the Y-shaped antibody molecule contains the __________, known as the Fc region.

    constant region

  • 40

    FC in Fc region stands for

    fragment crystallizable

  • 41

    It interacts to immune cells, and compliment protein and other cells in immune system

    constant region

  • 42

    2nd most common antibody in blood serum

    iga

  • 43

    It usually seen and responsible for mucosal secretion

    iga

  • 44

    colostrum milk (AAM) fights respiratory and GIT infection (AHEM)

    iga

  • 45

    release histamine for allergy causing runny nose or coughing

    ige

  • 46

    Least or low in level and its function is still uncertain

    igd

  • 47

    It has the largest structure and the 3rd most common antibody

    igm

  • 48

    Responsible for the clumping microorganism such as bacteria and virus

    igm

  • 49

    most common antibody

    igg

  • 50

    type of igA responsible for immune homeostasis

    iga1

  • 51

    type of iga responsible for everting inflammation

    iga2

  • 52

    type igG that serves as a marker for antigen or pathogens

    igg1

  • 53

    type of igG reponsible for bacterial infection, specifically encapsulated bacteria

    igg2

  • 54

    a type of IgG responsible for neutralizing virus/toxin

    igg3

  • 55

    a type of IgG responsible for allergy

    igg4

  • 56

    for diagnostic and a mixture of antibodies that are produced by different B cells in response to a particular antigen or foreign substance.

    polyclonal antibody

  • 57

    Laboratory-made proteins which mimic the immune system's ability to fight off harmful pathogens (virus/ Bacteria)

    monoclonal antibody

  • 58

    naturally occurring cancers cells derived from B cells and which therefore express immunoglobulin genes.

    myelomas

  • 59

    It is a type of monoclonal antibody engineered to reduce immunogenicity and increase their compatibility with the human system.

    humanized antibody

  • 60

    is a humanized antibody that targets HER2- positive breast cancer cells.

    trastuzumab (herceptin)

  • 61

    Process of cancer therapy

    binding to her2 receptors, inhibiting cell signalling, immune system activation, antibody dependent cellular cytotoxicity, antibody dependent cellular phagocytosis, direct inhibition of tumor growth

  • 62

    Aka Healthcare-associated or acquired infection

    nosocomial infection

  • 63

    an infection that occurs in a hospital or healthcare setting as a result of medical care or treatment.

    nosocomial infection

  • 64

    Infection from healthcare provider

    direct

  • 65

    infection from facilities

    indirect

  • 66

    prevent the bacteria from binding to the extracellular matrix protein, fibrinogen.

    clumping factor a

  • 67

    field of biotechnology that focuses on modifying or designing antibodies to enhance their specificity, affinity, stability, and therapeutic properties.

    antibody engineering

  • 68

    are two types of antibody fragments that are smaller components of full antibodies.

    fab and fv

  • 69

    are engineered antibody molecules designed to have specific properties and functions, particularly in the context of immunotherapy and targeted cancer treatment

    diabodies and bispecific antibody constructs

  • 70

    These are dimeric antibody fragments created by combining two antigen-binding regions of an antibody. They are designed to simultaneously bind to two different antigens or epitopes. They are relatively small, with a molecular weight of approximately 55-60 kDa, making them smaller than ful antibodies.

    diabodies

  • 71

    They are engineered molecules that combine the binding specificity of two different monoclonal antibodies within a single molecule. They have the ability to simultaneously bind to two different antigens or cells. This property allows them to bridge immune cells with target cells, enhancing immune responses. They are generally larger than diabodies and smaller than full antibodies.

    bispecific antibody constructs

  • 72

    It is widely uaed to detect and estimate the concentration of a protein in a sample

    elisa