記憶度
10問
27問
0問
0問
0問
アカウント登録して、解答結果を保存しよう
問題一覧
1
is a key player of the adaptive immune response that is responsible for humoral immunity in mammals.
b cells
2
The surfaces of bacteria and viruses are coated with _________ and _________ that are recognized by antibodies in the host organism.
glycoprotein , lipoprotein
3
The surfaces of bacteria and viruses are coated with glycoprotein and lipoproteins that are recognized by _______ in the host organism.
antibodies
4
It is a toxin or other foreign substance which induces an immune response in the body
antigen
5
It is a protein produced by the body's immune system when it detects harmful substances, called antigens.
antibodies
6
The immune system mediates immunity to various infectious agents through specific immunity or _________ immunity •
acquired
7
Antibodies only recognize a small _______ or dimple on the surface of a protein.
ridge
8
The region of the antigen that binds to the antibody is called an
epitope
9
are encoded by a family of genes that are different for every person.
mhc receptors
10
b cells originate in the
bone marrow
11
The “B” in B-cells came from the word _____
bursa
12
responsible for producing antibodies
b cells
13
Coats bacteria and causes them to be unaffected by antibiotics
biofilm
14
other term for antibody
immunoglobulin
15
It is a glycoprotein that is made in response to antigen
immunoglobulin
16
binding site of the antigen and can be altered depending on the type of antigen
variable region
17
A region in antibody where it doesn’t undergo any changes
constant region
18
2 types of specific or acquired immunity
humoral response, cellular response
19
It is a response whose responsible are the b cells. Antibodies produced by the b cells do not kill the cell, but only bind or attack the invaders outside the cell.
humoral response
20
It is a response whose responsible are the T cells.
cellular response
21
aka the killer cells. They kill the infected cells which lead to cell death
cytotoxic t cells
22
Stimulate B-cell to produce more antbodies. Help develop the cytotoxio cell.
helper t cells
23
It is a cell whose function is to engulf foreign substances
macrophage
24
Responsible for activating helper t cells
mhc class 1
25
mhc stands for
major histocompatibility complex
26
Responsible for activating cytotoxic t cells
mhc class 2
27
3 segments in human
variable, diversity, joining
28
Attachment process of antibody to the antigen
preparation, recognition, response, refinement, memory
29
advantages of surface antigen
recognition, cell evasion, identification, biofilm formation
30
The great diversity of antibodies - GENE SHUFFLING
gene segments, rearrangement, combinatorial diversity, junctional diversity, somatic hypermutation, selection
31
consist of two identical heavy chains
heavy chains
32
It contributes to the antibody structure’s overall stability
heavy chains
33
2 regions of each heavy chains
constant region (ch), variable region (vh)
34
have two identical light chains that are smaller that heavy chains
light chains
35
2 regions of each light chains
constant region (cl), variable region (vl)
36
The tip of each arm of the Y-shaped antibody molecule contains an _____ aka FAB
antigen-binding site
37
FAB stands for
fragment antigen binding
38
It is a antibody structure formed by both light and heavy chains
antigen-binding site
39
The stem of the Y-shaped antibody molecule contains the __________, known as the Fc region.
constant region
40
FC in Fc region stands for
fragment crystallizable
41
It interacts to immune cells, and compliment protein and other cells in immune system
constant region
42
2nd most common antibody in blood serum
iga
43
It usually seen and responsible for mucosal secretion
iga
44
colostrum milk (AAM) fights respiratory and GIT infection (AHEM)
iga
45
release histamine for allergy causing runny nose or coughing
ige
46
Least or low in level and its function is still uncertain
igd
47
It has the largest structure and the 3rd most common antibody
igm
48
Responsible for the clumping microorganism such as bacteria and virus
igm
49
most common antibody
igg
50
type of igA responsible for immune homeostasis
iga1
51
type of iga responsible for everting inflammation
iga2
52
type igG that serves as a marker for antigen or pathogens
igg1
53
type of igG reponsible for bacterial infection, specifically encapsulated bacteria
igg2
54
a type of IgG responsible for neutralizing virus/toxin
igg3
55
a type of IgG responsible for allergy
igg4
56
for diagnostic and a mixture of antibodies that are produced by different B cells in response to a particular antigen or foreign substance.
polyclonal antibody
57
Laboratory-made proteins which mimic the immune system's ability to fight off harmful pathogens (virus/ Bacteria)
monoclonal antibody
58
naturally occurring cancers cells derived from B cells and which therefore express immunoglobulin genes.
myelomas
59
It is a type of monoclonal antibody engineered to reduce immunogenicity and increase their compatibility with the human system.
humanized antibody
60
is a humanized antibody that targets HER2- positive breast cancer cells.
trastuzumab (herceptin)
61
Process of cancer therapy
binding to her2 receptors, inhibiting cell signalling, immune system activation, antibody dependent cellular cytotoxicity, antibody dependent cellular phagocytosis, direct inhibition of tumor growth
62
Aka Healthcare-associated or acquired infection
nosocomial infection
63
an infection that occurs in a hospital or healthcare setting as a result of medical care or treatment.
nosocomial infection
64
Infection from healthcare provider
direct
65
infection from facilities
indirect
66
prevent the bacteria from binding to the extracellular matrix protein, fibrinogen.
clumping factor a
67
field of biotechnology that focuses on modifying or designing antibodies to enhance their specificity, affinity, stability, and therapeutic properties.
antibody engineering
68
are two types of antibody fragments that are smaller components of full antibodies.
fab and fv
69
are engineered antibody molecules designed to have specific properties and functions, particularly in the context of immunotherapy and targeted cancer treatment
diabodies and bispecific antibody constructs
70
These are dimeric antibody fragments created by combining two antigen-binding regions of an antibody. They are designed to simultaneously bind to two different antigens or epitopes. They are relatively small, with a molecular weight of approximately 55-60 kDa, making them smaller than ful antibodies.
diabodies
71
They are engineered molecules that combine the binding specificity of two different monoclonal antibodies within a single molecule. They have the ability to simultaneously bind to two different antigens or cells. This property allows them to bridge immune cells with target cells, enhancing immune responses. They are generally larger than diabodies and smaller than full antibodies.
bispecific antibody constructs
72
It is widely uaed to detect and estimate the concentration of a protein in a sample
elisa