Bile acids are hydrophobic and require a carrier in the portal blood

Most of the uric acid enters the blood and is eventually excreted in the urine.

Citric acid cycle intermediate could participate in Heme Biosynthesis.

PKU test screens newborn babies on congenital hypothyroidism.

Reduction of androstenedione at the C17 position results in the formation of Glucagon, the most potent adrenal androgen.

Creatinine is synthesized in the liver and excreted by the help of kidney.

Gout is a disorder characterized by low levels of uric acid— the end product of purine catabolism— in blood (hypouricemia)

Glycogen synthase and DNA synthase require a primer.

The strand that is being copied in the direction of the advancing replication fork is called the leading strand and is synthesized continuously is Lagging strand

Initiation codon always encodes amino acid tryphtophan.

Initiation codon always encodes amino acid tryphtophan

Thyroglobulin is the transporter plasma protein for thyroid hormones – T3, T4

The β chains of Insulin is identical in all of these hormones, and distinct α-chain impart hormone uniqueness

Hormone, which act on intracellular receptors is - Thyroxine.

Liver's inability to detoxify ammonia, might lead to hepatic encephalopathy

the obstructive jaundice, it is mainly conjugated bilirubin that increases, because liver is intact.

Bilirubin and biliverdin, both are the products of heme synthesis

Dopamine and norepinephrine are synthesized in the brain and function as neurotransmitters

The catecholamines are synthesized from Alanine

The bile acids are amphibolic

The main metalloporphyrin in the body is heme, which has a ferrous Fe 3 iron atom coordinated by protoporphyrin IX

Heme is synthesized from glycine and succinyl CoA precursors via a complex series of reactions

Bilirubin is not very water-soluble, so most of it is carried to the liver bound to albumin

Most of the urobilinogen is oxidized to urobilin , which turns the feces brown

Bilirubin is conjugated in the gallbladder by glucuronil transferase

Hyperuricemia is typically asymptomatic and does not lead to gout

The very first step in pyrimidine synthesis is the formation of carbamoylaspartate, catalyzed by aspartate transcarbamoylase

Phosphodiester bonds join the 5'-hydroxyl group of the deoxy-pentose of one nucleotide to the 53-hydroxyl group of the deoxy pentose of an adjacent nucleotide through a phosphate group

Polymerases use only ssDNA as a template

DNA is negatively charged, histones and Mg2+ions help to neutralize the charge

Most of the uric acid enters the blood, and is eventually excreted in the urine.

Estrogens are formed by the aromatization of androgens, which requires O2 and NADPH

Citrulline is an non-protein amino acid which works as an intermediate in urea biosynthesis

5-hydroxytryptophan is decarboxylated to MAO , which is also degraded by serotonin

Ferrochelatase decreases the rate of iron insertion into protoporphyrin IX.

Hormones may act as coenzymes

Within cells of the RE system, heme is degraded to bilirubin

Most of the urobilinogen is oxidized to stercobilin, which turns the urine brown

Condensation of Gly and succinyl CoA to produce -aminolevulinic acid (ALA) is the rate-limiting step of heme biosynthesis

Unconjugated bilirubin is normally secreted.

DOPA is decarboxylated in a reaction requiring pyridoxal phosphate (PLP) to form dopamine

Progesterone can serve as a precursor for mineralocorticoids.

Hydroxylases require molecular oxygen and NADPH are essential

Inside a polysome, ribosomes are translating different types of proteins

Catecholamine degradation results in the synthesis of S-adenosylmethionine

Ribonucleotide reductase(ribonucleoside diphosphate reductase) is composed of two nonidentical dimeric subunits

Cyclic AMP was the first intracellular second messenger signal identified in mammalian cells

The phosphoprotein dehydrogenase are themselves subject to regulation by phosphorylation dephosphorylation reactions

The SSB proteins are not enzymes, but rather serve to shift the equilibrium between dsDNA and ssDNA in the direction of the single-stranded forms

The 3' →5' exonuclease activity that proofreads the newly synthesized DNA chain like DNA polymerase III

Leucine and lysine are the only exclusively glucogenic amino acids found in proteins

Creatinine and urea elevation could be an indicator for myocardial infarction

Aminotransferases are intracellular enzymes and their plasma concentration increase usually indicates pathology

The main metalloporphyrin in the body is heme, which has a ferrous Fe 3 iron atomcoordinated by protoporphyrin IX

Theca cells are the source of androstenedione and testosterone

The phosphate groups are responsible for the positive charges associated with nucleotides, and cause DNA and RNA to be referred to as “nucleic acids

The purine ring is constructed primarily in the liver

Regulation of heme synthesis in erythroid cells occurs at enzymes catalyzing several steps of the pathway, including ferrochelatase

Hemin inhibits ALA synthase only by using an allosteric mechanism

The β chains of Insulin is identical in all of these hormones, and distinct α-chain impart hormone uniqueness

Heme synthesis in the liver can be inhibited by drug consumption

Hormones are only synthesized in specialized organs called glands

Telomeres are complexes of noncoding DNA plus proteins located at the ends of linear chromosomes

The main metalloporphyrin in the body is heme, which has a ferrous Fe 3 iron atom coordinated by protoporphyrin IX.

Phosphatidic acid is the simplest phosphoglyceride

Genetic disorders associated with an inability to properly degrade the glycosphingolipids result in lysosomal accumulation of these compounds

The bacteria in the kidney convert bilirubin to urobilins, which gives urine its color.

Cortisol activates phospholipase A2 activity

Arachidonic acid turning to PGH2 is catalyzed by prostaglandin endoperoxide synthase.

Phosphodiester bonds join the 5'-hydroxyl group of the deoxy-pentose of one nucleotide to the 53-hydroxyl group of the deoxy pentose of an adjacent nucleotide through a phosphate group

Infant RDS (Respiratory distress syndrome) is caused by deficiency of lung surfactant