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Module 4 Easy
  • Justine Kyle Sabayo De Asis

  • 問題数 100 • 8/3/2024

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    問題一覧

  • 1

    What is the neurotransmitter of all preganglionic autonomic fibers and parasympathetic fibers?

    Acetylcholine

  • 2

    What is the rate-limiting enzyme in the synthesis of catecholamines?

    Tyrosine hydroxylase

  • 3

    Which of the following is a MAO-B specific inhibitor?Which of the following is a MAO-B specific inhibitor?

    Selegiline

  • 4

    Which of the following is not used for Alzheimer's disease?

    Physostigmine

  • 5

    This is the first line inotrope for cardiogenic shock.

    Dobutamine

  • 6

    This metabotropic receptor works by stimulating adenylyl cyclase this increasing levels of CAMP

    Gs

  • 7

    Ondansetron and Granisetron inhibit what receptor?

    5HT3

  • 8

    Which of the following is not used as an antiemetic?

    Alosetron

  • 9

    Which of the following is the least potent H2 blocker?

    Cimetidine

  • 10

    Which of the following is the drug of choice for hypercholesterolemia?

    Simvastatin

  • 11

    Effects of insecticide poisoning, except

    Bronchodilation

  • 12

    An NSAID that was required to add a black box warning in its label due to increased risk of thrombosis and stroke.

    Rofecoxib

  • 13

    Which of the following COX enzymes is responsible for maintaining homeostasis in the body and is known as the "Housekeeping COX".

    COX I

  • 14

    NAPQI is the toxic metabolite of acetaminophen or paracetamol. What does NAPQI stand for?

    N-Acetyl p-benzoquinone imine

  • 15

    What medication has this chemical structure?

    Paracetamol

  • 16

    Also known as acetylated morphine.

    Heroin

  • 17

    A non-purine xanthine oxidase inhibitor.

    Febuxostat

  • 18

    Based on the lab results, a patient's HDL levels should be increased. Which among the following medications would be the most effective in increasing the HDL levels in the body?

    Niacin

  • 19

    Which of the following will not cause Extrapyramidal Symptoms in treating psychosis?

    Clozapine

  • 20

    Which of the following anxiolytics can increase the frequency of chloride channel opening?

    Triazolam

  • 21

    This element is used in rheumatoid arthritis.

    Gold

  • 22

    This is used for the Tensilon Test.

    Edrophonium

  • 23

    Which H2-receptor antagonist is the most potent?

    Famotidine

  • 24

    Which H2-receptor antagonist is the prototype?

    Cimetidine

  • 25

    The following clotting factors are targeted by warfarin, except?

    I

  • 26

    This drug is not a proton pump inhibitor.

    Aripiprazole

  • 27

    Which of the following is the drug of choice for septic shock?

    Norepinephrine

  • 28

    Which of the following drugs is not non-steroidal in structure?

    Micacurium

  • 29

    Neuromuscular blockers act on:

    Nicotinic receptors

  • 30

    Clinical use of ritodine:

    Tocolytic

  • 31

    SSRIs, except:

    Fluphenazine

  • 32

    All are intermediate acting Benzodiazepines, except: Answer:

    Escitalopram

  • 33

    What is the mechanism of action of tranexamic acid?

    Inhibits plasminogen activation

  • 34

    A drug with a narrow therapeutic index means that the drug is:

    Unsafe

  • 35

    The primary mechanism of neurotransmitter release is accomplished by what process?

    Exocytosis

  • 36

    Dry cough is a side effect of which antihypertensive?

    ACE inhibitors

  • 37

    High-ceiling diuretics are:

    Loop diuretics

  • 38

    It is defined as a measure of the ability of a drug to evoke an active response.

    Intrinsic activity

  • 39

    Antiplatelets, except:

    Argatroban

  • 40

    Branch of pharmacology that deals with the biochemical and physiologic effects of drugs in biological systems and the mechanisms by which these effects were produced:

    Pharmacodynamics

  • 41

    Which of the following monoamine oxidase inhibitors is indicated for parkinsonism only?

    Seleginine

  • 42

    Aldosterone is produced by:

    Zona glomerulosa

  • 43

    Which neurotransmitter is primarily responsible for transmission in the sympathetic nervous system?

    Norepinephrine

  • 44

    Which of the following describes an agonist?

    Affinity with intrinsic activity

  • 45

    Which type of receptor inhibits adenylyl cyclase?

    Gi

  • 46

    Which of the following drugs should not be used by patients with gout?

    Tolmetin

  • 47

    Lipolysis is due to the activation of which receptor?

    Beta-3

  • 48

    What type of antagonism is demonstrated when protamine sulfate counters the effects of heparin?What type of antagonism is demonstrated when protamine sulfate counters the effects of heparin?

    Chemical antagonism

  • 49

    Drug that is used as hair grower:

    Minoxidil

  • 50

    Peakless insulin

    Glargline

  • 51

    Which of the following is the drug of choice for absence seizure?

    Ethosuximide

  • 52

    Which of the following are autacoids?

    Serotonin, Eicosanoids, Bradykinin, Histamine

  • 53

    It contains the highest concentration and greatest number of prostaglandins.

    Seminal fluid

  • 54

    The only NSAID that is not a weak acid

    Nabumetone

  • 55

    A prostaglandin analog used to temporarily maintain the patency of ductus arteriosus in neonates?

    Alprostadil

  • 56

    Preferred anticoagulant for pregnant patients

    Fondaparinux

  • 57

    Which of the following parameter/s is/ are required for heparin monitoring?

    aPTT

  • 58

    Sodium-glucose cotransporter-2 (SGL2) inhibitors are drugs that are used to treat

    Type 2 diabetes

  • 59

    Which of the following drugs is a mixed adrenergic antagonist?

    Labetolol

  • 60

    Insulin is chemically classified as a

    Protein

  • 61

    Sotalol is an anti arrhythmic drug classified under

    Class III

  • 62

    An experienced mountaineer experienced dizziness, insomnia, and headache after quickly reaching the summit. What drug would be recommended for this nerson?

    Diamox

  • 63

    Which vasodilator causes hyperglycemia?

    Diazoxide

  • 64

    Which of the following is an anticoagulant drug?

    Hirudin

  • 65

    Which of the following is not an opiod receptor?

    y (inversed)

  • 66

    “-sartans” are

    Angiotensin converting enzyme inhibitors

  • 67

    Which is/are the indication of the drug Tamoxifen?

    Breast cancer

  • 68

    Which is the drug of choice for status epilepticus?

    Lorazepam

  • 69

    Which is the drug of choice for febrile seizure?

    Phenobarbital

  • 70

    The process of drug metabolism and excretion constitute:

    Elimination

  • 71

    Primary site of drug excretion

    Kidney

  • 72

    BCS Classification: Low solubility and high permeability

    Class II

  • 73

    The rate limiting favtor in the dissolution of drugs:

    Disintegration

  • 74

    The following are incorrect regarding passive transport, except:

    C. II, III, IV

  • 75

    Which of the follwing is metabolized by MAO-B?

    Dopamine

  • 76

    The following are correct regarding active transport, except:

    D. III, IV

  • 77

    This represents the drug concentration needed to just barely produce a toxic effect:

    Minimum Toxic Concentration

  • 78

    What is the most abundant CYP enzyme?

    CYP3A4

  • 79

    Acidic drugs bind to:

    Albumin

  • 80

    Initial pathway of elimination

    Metabolism

  • 81

    Which of the following correctly states the factors affecting absorption?

    Smaller surface area decreases rate of absorption

  • 82

    Carrier-mediated transport is said to be:

    Saturable

  • 83

    Which of the following refers to efficacy?

    Maximum achievable response

  • 84

    Pharmaceutical equivalents that can be expected to have the same clinical effect and safety profile when administered to patients under the same conditions specified in the labelling:

    Therapeutic equivalent

  • 85

    What does the term “bioavailability “ refer to?

    The proportion of the administered drug that reaches the systemic circulation

  • 86

    What is the most important organ for the absorption of orally administered drugs?

    Small Intestine

  • 87

    Refers to the order of reaction in which the concentration of a drug is decreasing at a rate that is proportional to the concentration of the drug remaining

    First

  • 88

    In a drug interaction scenario, what would best describe the result if Drug A induces the metabolism of Drug B?

    Decrease in blood level of Drug B

  • 89

    True about bioavailability:

    Greatly affected by drug absorption

  • 90

    What is the basis why acidic drugs are best absorbed in the stomach?

    Henderson-Hasselbalch equation

  • 91

    What is the antidote for acetaminophen toxictt?

    N-acetylcysteine

  • 92

    A toxicity associated with any chemical substance:

    Intoxication

  • 93

    A low molecular weight protein that binds to endogenous substances before contributing to the body's immune response:

    Hapten

  • 94

    This type of evidence can be obtained from the examination of organs and tissues of the dead.

    Post-mortem evidence

  • 95

    This occurs within 24 hours

    Acute

  • 96

    Mechanism of action of activated charcoal for gastrointestinal decontamination

    It adsorbs the poison

  • 97

    A patient on chronic opioid therapy for pain management is prescribed naloxone. What is the primary purpose of adding naloxone to the treatment regimen?

    To counteract opioid overdose

  • 98

    The term used to describe the frequency of occurrence of undesirable effects arising from exposure to a physical or chemical agent

    Risk

  • 99

    Toxicity due to paracetamol overdose causes depletion of

    Glutathione

  • 100

    Which drug of abuse is sold as “angel dust”

    Ketamine