Polycythemia puts babies at risk for:

What is the average life span of an erythrocyte?

Increased: pCO2, H+, 2,3-DPG, Temp

Vegetarians are at risk for:

Elevated Reticulocyte Level

Kidney disease leading to decreased Erythropoietin production causes:

Autosomal Recessive- Alpha and Beta Types - Mutation of HBB gene

Where does the sequestration and destruction of aged erythrocytes normally take place?

Protoporphyrin IX is comprised of.

What is the correct sequence in coagulation:

Indicates amount of stored Iron

Low Fe, B12, Folate intake causes:

What MCV should you expect in Iron Deficiency Anemia

MCV < 80

Hemaglobin Metabolism

Low WBC and PLT levels alone indicate:

Which of the following is not a normal component of plasma?

B12 and Folate Deficiency, Myelodysplastic Syndrome, Adverse Drug Reaction, Alcohol Abuse, Hypothyroidism:

Proinflammatory cytokines inhibit erythropoietin, destroy immature erythroblasts, and stimulate release hepcidin

As an individual ages:

After lysis/hemolysis of RBCs, Hbg is:

Has the greatest affinity for oxygen.

Granulocytes contain:

What can interfere with Ferritin levels when diagnosing Iron Deficiency Anemia?

Shortened RBC lifespan in Aging causes:

Decrease O2 affinity, Hgb more unstable and prone to early breakdown

Pernicious Anemia is what type of anemia?

Detecting Erythroblasts in Lab Test

Iron, Folate, B12 Deficiencies. Hemolytic Anemia.

Co-morbid inflammatory diseases cause:

What type of anemia is Folate Deficiency Anemia?

Aging causes RBCs to become:

Pregancy increases metabolism which can lead to:

Increased in Iron Deficiency Anemia

Average size of RBC

Catalyzes reversible reaction between CO2 and H2O to form HCO3

Treating Thalassemia with transfusions risks:

Smoking Increases:

MCHC < 27

Fetal Hbg is comprised of.

Symptoms: paraesthesia, decreased balance, sore tongue, increased homocysteine

Decreased in inflammation and malignancy

Why do lymph nodes enlarge and become tender during an infection?

Each Hbg Fe can carry.

Decreased: pCO2, H+, 2,3-DPG, Temp, HbF

RBC production last month gestation to 5 years.

GI Bleeding associated with

Normocytic

Granulocytes and Monocytes

What is the correct sequence in fibrinolysis?

Storage of Transferrin not in use:

RBCs with Hgb S has low O2 capacity and found in:

2 Alpha 2 Beta Chains

RBC production in early gestation

Stores too much Iron in the liver. Decreases oral absorption of Iron in GI tract, and blocks release of Iron from Reticuloendothelial system. Found in Anemia of Chronic Illness.

Which of the following minerals is required for erythropoiesis?

In low oxygen, Erythropoietin makes Hematopoietic Stem Cells that makes.

MCV > 100

Chron’s Disease and Gastric Bypass causes Iron Deficiency Anemia due to:

Porphyrin is converted to:

The purpose of erythropoietin is:

Anemia

Oxygen Carrying Capacity of Hemoglobin

Shorter RBC lifespan r/t less effective DNA synthesis, lack intrinsic factor, autoimmune can atrophy gastric cells

Proteins available to bind Iron

Thalassemia is what type of anemia?

Macrophages release Fe from Hgb and transported as:

Alpha, Beta, Gamma, Delta, Fetal

Amount of Hbg in RBC compared to size (color of RBC)

Anemia of Chronic Illness, Sickle Cell Amemia, Aplastic Anemia, Hemolytic Anemia, CKD, HIV, Acute Blood Loss:

Iron Deficiency Anemia, Anemia of Chronic Ilness, Thalassemia, Sideroblastic Anemia

New RBC will have:

MCHC >= 27

Eosinophils

Anemia without elevated Reticulocyte

When a blood cell is damaged:

Anemia, hypoxemia, circulatory failure, high altitude all stimulate.

Low tissue oxygen triggers

The greatest proportion of total body iron is located in the:

Pluripotent Stem Cell makes Erythrocyte CFU that leads to.

Sickle Cell is what type of anemia?

Hemolytic Disease of the Newborn:

MCV 80-100

Ability of the body to transport Iron

Lymphocytes and Plasma Cells

Periods of rapid growth (toddler and adolescents) can cause:

Normocytic

RBC production after 5 years

Anemia is:

Labs: increased - bilirubin, phosphorus, uric acid, hemoglobinuria; decreased - haptoglobin

Erythropoietin is released by the:

Succinyl-Co-A from Krebs binds with Glycine to form.

Impaired RNA/DNA synthesis, found commonly in alcoholics, elderly, effects of aspirin, fetal neural tube defects.

Pancytopenia - decreased “all cell lines” (RBC, WBC, PLT)

Heme Molecule

Sickle Cell Disease and Thalassemia cause:

Can be both Hypocytic or Normocytic

RBC lysis yields which of the following products?

Increases for every 1000 meters above sea level

Polycythemia is typically seen in: