問題一覧
1
Which drug has common adverse effects of polydipsia, polyuria, polyphagia, fine hand tremor and dermatologic reactions
lithium
2
The following statement is true regarding ramelteon
ramelteon is a melatonin receptor agonist
3
Which drug is not a long acting injetable formulation
haloperidol lactate
4
The synthesis pathway of norepinephrine is
tyrosine-dopamine-norepinephrine-epinephrine
5
Weight gain
histamine
6
The following drugs are considered firts line therapy for generalized anxiety disorder except
bupropion
7
Which drug is a non benzodiazepine anxiolytic which may be useful in patients unable to take benzodiazepines
buspirone
8
Which of the following drugs are used in the treatment of bipolar disorder
lithium and valproic acid
9
This extradyramidal side effect usually occurs when the patient has ben taking antipsychotics for >1 year and occur in various areas of the body - face, tongue, hips, and extremities. Common movement disorders include tounge chewing, lip smacking, and rhythmic movements of the trunk
tardive dyskinesia
10
Which neurotransmitters are responsible in promoting sleep
aota
11
Sedation
histamine
12
Non stimulants are considered 2nd line drugs for adhd. Which non stimulant is a selective norepinephrine reuptake inhibitor
atomoxetine
13
Benzodiazepines potentiate gaba by binding to gaba receptors and provide rapid relief in anxiety attacks. The following bzd used as anxiolytic except
triazolam
14
Anxiety is associated with chronic ne overactivity combined with increased activity in the 5ht system
false
15
Urinary retention
cholinergic
16
Which hypnotic agent is a tricyclic antidepressant that produces it's effects through histamine blockade
doxepin
17
The major drawback to clinical use of benzodiazepines include
abuse potential and dependence liability
18
Alpha 2 agonists works by inhibiting central release of norepinephrine and may be a useful adjunct to stimulants for symptoms of hyperactivity, impulsivity, aggresion, or insomnia. The following are alpha 2 agonists
clonidine and guanfacine er
19
The following statements are true regarding adhd
aota
20
A bipolar patient has been binging on salty foods and is currently on lithium citrate syrup. What is likely goung to happen to this patient
patient lithium level may decrease and bipolar diseaseay worsen
21
Schizophrenia is usually a lifelong psychiatric disability but luckily there is a cure for it
false
22
Adverse effects of stimulant medications include all of the following except
bradycardia
23
Clinical depression os usually caused by an imbalance of neurotransmitters in the brain. Which is the correct statement
it is caused by a decrease in norepinephrine and serotonin levels
24
Which of the following antipsychotics have less affinity for dopamine receptors, therefore have less risk for eps
chlorpromazine and fluphenazine
25
Atypical antipsychotics improve the negative symptoms to some extent and have a calmkng effect. Which of the following is not an atypical antipsychotic
thiothexene
26
Ssri when guve together with mao inhibitors increase the risk of
serotonin syndrome
27
The typical antipsychotic agents are the following except
clozapine
28
The destruction of norepinephrine and dopamine in the synapses can be prevented by
monoamine oxidase inhibitors
29
A female schizophrenic patient exhibited galactorrhea, gynecomastia and amenorrhea and doctor wants to know if these are drug related adverse effects. Patient is currently taking haloperidol 20mg twice daily. Which statement is correct regarding haloperidol
haloperidol can decrease dopamine level which in turn increases prolactin level
30
The following drugs block norepinephrine and serotonin reuptake inti the neurons causing improved mood except
paroxetine
31
Patient came to your pharmacy with a prescription for sertraline 25mg every morning and phenelzine 50mg in the evening. As a pharmacist, what would you do
call the doctor regarding potential drug drug interaction
32
Which antidepressant is fda approved for smoking cessation and inhibits reuptake of norepinephrine and dopamine
bupropion
33
Patients who suffered from constipation, blurred vision, urinary retention or dry mouth should avoid which of the following antipsychotics
thioridazine
34
Hypertensive crises occurs when increased levels of ne, vuild in the body, after ingesting tyramine containing foods like wine and cheese or decongestants. Which of the following antidepressants can potentially cause this when taken with these tyramine rich foods
phenelzine and isocarboxazid
35
A newly diagnosed schizophrenic patient suffering from impoverished speech and thinking, lsck of social drive, flatness of emotional expression, and anhedonia. Which antipsychotic drug will you least recommend to the doctor
chlorpromazine
36
A patient exhibited pseudoparkinsonism and akathisia after being started on an antipsychotic medication. Which agent do you think might have caused these adverse effects
haloperidol
37
Stimulant medications block reuptake of both dopamine and norepinephrine. These include the following drigs
methylphenidate and amphetamine salts
38
Orthostatic hypotension
adrenergic
39
Anxiety is described as a comfortable feeling of vague fear or apprehension accompanied by mental features and physical symptoms
false
40
Which salt of lithium is available as immediate release, controlled release, or extended release tablets
carbonate
41
Bzed receptor agonists have potential for abuse and dependence, hangover effect, and rebound insomnia upon discontinuation. The following drugs are bzd receptor agonists except
zonisamide
42
Which is a rare and potentially fatal adverse effect of antipsychotics with symptoms that include muscle rigidity, fever with temperature as high as 41⁰c, altered mental status and stupor, unstable blood pressure myoglobinemia with elevated creatinine kinase
neuroleptic malignant syndrome
43
Which statement regarding long acting injectables is correct
long acting injectable formulations are administered intramuscularly in patients non compliant with oral meds. duration up to 2-4 weeks
44
Which atypical antipsychotic is the last resort drug and may increase risk of agranulocytosis
clozapine
45
Which hypnotic has been associated with parainsomnia including sleep waling, eating, and driving
zolpidem
46
Gynecomastia and galactorrhea
dopamine
47
The following antidepressants selectively inhibit reuptake of serotonin except
atomoxetine
48
Patient suffering from auditory or visual hallucinations, delusions, illogical thought and speech and combative and hostile exhibits which type of symptoms
positive
49
Which of the following statements are true regarding lithium therapy
aota
50
The thalamus area of the brain controls response inhibition. It works like gate sending signals to allow or stop behaviors. In adhd, the thalamus gate is broke
true