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chapter 27 fluid, electrolytes, and acid-base homeostasis
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  • 問題数 27 • 4/21/2024

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  • 1

    What are the 2 types of fluid ?

    intracellular fluid- all fluid contained inside cells, and comprises 2/3 of all body fluids, extracellular fluid- all fluid outside the confines of the plasma membranes that contain all intracellular contents * 1/3 of all body fluid is contained in the extracellular compartment

  • 2

    In females what are the percentages of body mass ?

    45% solids, 55% fluids

  • 3

    In males what are the body mass percentages ?

    40% solids, 60% fluids

  • 4

    What is the total body fluid ratio in males and females

    2/3 intracellular fluid, 1/3 extra cellularfluid

  • 5

    What is the extracellular fluid percentages ?

    80% interstitial fluid, 20% blood plasma

  • 6

    What are the two general barriers separating these fluid compartments ?

    plasma membrane of individual cells, blood vessel walls

  • 7

    What is hyponatremia ?

    low sodium content (water content is too high)

  • 8

    Explain water loss

    GI tract (100 mL), lungs (300 mL), skin (600 mL), kidneys (1500 mL)

  • 9

    Explain water gain

    metabolic water (200 mL), ingested foods (700 mL), ingested liquids (1600 mL)

  • 10

    Is water loss and water gain equal

    yes

  • 11

    If mild dehydration occurs, what happens to blood volume/pressure ?

    decreases

  • 12

    Explain how the RAA system fixes this

    stimulates kidneys to release renin, promotes formation of angiotensin ll, increase blood osmolarity

  • 13

    Where is the thirst center located ?

    hypothalamus

  • 14

    What is the main factor that determines body fluid volume ?

    water loss and intake

  • 15

    If water volume/pressure goes up which hormone is secreted ?

    atrial natriuretic peptide hormone

  • 16

    What is the main cation and anion in extracellular and intracellular fluid ?

    extracellular fluid- cation is Na+ and anion is Cl-, intracellular fluid- cation is K+ and anions are proteins and phosphates

  • 17

    What plasma anion is the most significant ?

    chloride

  • 18

    Intercalated cells of renal tubule regulates which anion

    bicarbonate

  • 19

    Which hormones regulate calcium levels ?

    parathyroid hormone , calcitonin

  • 20

    Explain the protein buffer system

    Proteins composed of amino acids and contain at least one carboxyl groups (-COOH) and at least one amino group (NH2)

  • 21

    When do protein buffer release or combine with a H ?

    Free carboxyl group acts like an acid by releasing H+ when pH rises (alkaline conditions) , Free amino group at other end can act as a base by combining with H+ when pH falls (acidic conditions)

  • 22

    What is the blood pH is acidosis and alkalosis ?

    acidosis- below 7.35, alkalosis- above 7.45

  • 23

    What is respiratory alkalosis ?

    occurs whenever too much CO2 is lost (PCO2 falls below 35 mmHg)

  • 24

    What is metabolic alkalosis ?

    occurs whenever non-respiratory acids are lost

  • 25

    What is metabolic acidosis ?

    is characterized by a decreased bicarbonate level and decreased pH

  • 26

    What is respiratory acidosis ?

    abnormally high PCO2 in systemic arterial blood (above 45 mmHg)

  • 27

    What can hypoventalion and hyperventilation cause ?

    hypoventilation- bring pH into normal range , hyperventilation- losing too much CO2