問題一覧
1
The absorption of molecules and particles is done through:
Endocytosis
2
Among the functions of the tyrosine kinase receptors are:
Introducing glucose into the cell; protein synthesis (insulin), Inhibition of angiogenesis (VEGF), Cellular proliferation (Epidermal Growth Factor)
3
The cytoskeleton presents microfilaments of:
Actin, Actin-associated proteins
4
Zonula adherens:
In epithelial tissue is immediatly below the zonula occludens, At the level of the heart muscle is fascia adherens, The actin filaments are arranged parallel in the junction
5
Are membrane receptors:
Tyrosine kinase receptors, Ion channel receptors
6
Desmosome:
Has a space between cell membranes of 25-35nm, Has as the transmembrane linker protein desmocholin, Is a disk junction
7
Symport transport is a transport mode:
Secondary active
8
Functions of tight junctions:
Not permeable for ions, Selective barriers, Maintain cell and tissue polarity
9
Choose the right variants regarding the characteristics of RAS protein response:
Acts as a switch between the 2 conformations, active with GTP and inactive with GDP, It was initially discovered in a mutant, hyperactive form that promotes cancer cell transformation
10
Cilia are made of:
2 central microtubules and 9 microtubule doublets
11
The following statements about cytomembranes are true:
Generates the “specific surface area” for the development of biochemical processes, Ensures adequate compartmentalization for the simultaneous development of biochemical processes
12
The glypiation process:
Is specific to ectoproteins, Contributes to the anchoring of proteins to the lipid bilayer through conjugations with lipid elements, Contributes to the anchoring of proteins to the lipid bilayer by the formation of the glyco-phosphatidyl-inositol anchor
13
In facilitated diffusion carrier proteins:
Change their conformation, alternating opening to the extra- or intra-cellular space
14
In active secondary transport:
The transport against the gradient for a certain molecule is coupled with the transport of another solute according to its gradient, Couples transport against the gradient with ATP hydrolysis
15
In the transport of Glucose - Sodium:
Na+ is transported against the concentration gradient, Glucose is transported against the concentration gradient
16
Zonula adherens represents:
An anchoring junction on actin filaments, A communication junction
17
Linker transmembrane proteins in desmosomes are represented by
Desmoglein, Desmocholin
18
The junctional complex consists of a strict succession of 3 junctions:
Zonula occludens, zonula adherens, desmosome
19
Hydrophilic signal molecules:
Need cell surface receptors, Represent the majority of the signal molecules
20
Receptors for thyroid hormones are found::
In the nucleus, bound to DNA
21
Ribosomes contain:
Proteins, RNA
22
The antibody of the tRNA recognizes:
mRNA Codon
23
Chromatin:
Is a complex composed of DNA, histones, RNA, non-histone proteins
24
Cell nucleus is present in the following Cells with the exception of:
Erythrocytes, Platelets
25
Roles of Golgi apparatus:
Protein maturation, Lysosome biogenesis, Membrane biogenesis
26
The following statements are true about Golgi complex:
The main function of the Golgi complex is to receive, sort and pack various materials produced by ER such as proteins, Transit through Golgi is done from cis face to trans face
27
Autocrine communication:
The cell produces a self-addressed message
28
Proteosynthesis:
Start on ribosomes attached to the ER
29
Mitocondria:
The mitocondrial synthesis of ATP is driven by an electro-osmotic gradient
30
Microtubules:
Can be found in the cell, Each microtubule subunit is a heterodimer composed of Alpha and Beta tubulin, Have a role in the transport of vesicles and organisms into the cytoplasm, 6 triplets of microtubules form a centriol
31
Symport:
Transport of the 2 molecules is done in the same direction
32
MTT method evaluates:
Cellular metabolism by evaluating NAD-dependent cellular oxidoreductase enzymes
33
Gene sequencing:
Allows to decipher the sequence of nucleotides that enter the structure of a gene, It is used to identify mutations
34
In the evolution of a cell culture, in the exponential phase:
Cells divide quickly
35
The expression level of a protein can be assesed by:
qRT-PCR, Western blot, Two-dimensional electrophoresis, Luminex
36
Evidence of the interstitial between the cells of the epithelium can be done through:
Silver impregnation
37
In DNA extraction, lipid lysis from cell membranes is done with
Detergents, Surfactants
38
In SDS-PAGE electrophoresis, protein separation is done:
By migrating to the electric field, based on molecular weight, By the uniform absorption of the SDS on the unit of protein mass, achieving a consistent load of negative loads, Using an acrylamide gel