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問題一覧
1
colonzization or invasion of pathogens to an organism with active growth and multiplication causes damage to the host
infection
2
as something which targers our own cell
auto immune disorder
3
hiv target cells
cd4 + cells
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normal cdt 4 cell count
500-1300 cells per microliter
5
aids progression cd4+ cells
less than 200
6
types of infection
as to cause of infection as to localization as to degree/ extent as to duration
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(as to cause of infection) self inflicted
autogenous infection
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(as to cause of infection) caused by non living material found in medical setting
iatrogenic infection
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(as to cause of infection) supposedly can non post threat unless the immune system is weakened
opportunistic infection
10
(as to cause of infection) any infection we can get from hospital
nosocomial infection
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(as to localization) starting point
local infection
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(as to localization) progression of localized infection - into a larger scope of area
focal infection
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(as to localization) covers the entire system
systemic infection
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(as to extent/ degree) one oragnism and is very strong pathogen
primary infection
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(as to extent/ degree) second organism and able to enter becuase of weak state and experiencing primary infection
secondary infection
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(as to extent/ degree) multiplex of pathogens
mixed infection
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(as to duration) abrupt, sudden type of infection. dominance of pnms or neutrophils
acute infection
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(as to duration) long endured, spans longer duration
chronic infection
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(as to duration) infection that is passive type, usally inactive but it is present
latent infection
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(as to duration) type of infection whein is the middleway between acute and chronive infection
sub chronic infection
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routes of infection
direct and indirect
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(routes of infection) direct exposure to the pathogen
direct contact
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(routes of infection) no straigth forward exposure to the pathogen
indirect contact
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same generation, chil-child, mother-mother
horizontal direct contact
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two generations, mother to chid
vertical direct contact
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inanimate objects that may act as support system
fomites
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such as food, water, and air
vehicles
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arthropods and may be protozoans. referred to be smaller
vectors
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disease of animals transmissable to man
zoonosis
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specific illness or disorder with recognizable set of signs and symptoms
disease
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a change in a body function that is felt by a patient as a result of disease
symptom
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a changes in a body that can be measures or observed as a result if disease
signs
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a specific group of signs and syptoms that acompany a disease
syndrome
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disease that is brougth by pathogens
infectious disease
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classification of infectious disease
communicable contagious non communicable
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(classification of infectious disease) can be transferred
communicable
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(classification of infectious disease) can be transferred easily
contagious
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(classification of infectious disease) does not have the capacity to get transferred
non communicable
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phases in infectious disease
incubation period prodromal period clinical/ illness period decline period convalescnet/ recovery period
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(phases of infectious disease) starting point, entry of organism. to recogize the new environment
incubation period
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(phases of infectious disease) onset of signs and symptoms. hallmark or evidence of infection
prodromal period
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(phases of infectious disease) peak phase in infection
clinical/ illness period
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(phases of infectious disease) signs and symptom starts to disappear
decline period
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(phases of infectious disease) death or exit of pathogens
convalescent/ recovery period
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organism carrier/ harbors the infected agent
carrier
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types of carriers
casual chronic convalescent active
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number of occurent in a given period of time
incidence rate
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number of people affected/ total population in a given time period
morbidity rate
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number of deaths from a disease
mortatily rate
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isolated case
sporadic
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spans a large area
endemic
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larger area/ scope than endemic
epidemic
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inolves 2 or more countries
pandemic
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microorganisms that causes disease or infection
pathogens
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ability of the pathogen to produce disease to a host
pathogenecity
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has the capacity to casue infection
pathogenic
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does not have the capacity to cause infection
non pathogenic
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organism by nature can cause disease
true pathogens
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organisms can not cause disease to healthy individual
false pathogen
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is the relationship between normal microbiota and the host
symbiosis
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is a symbiosis in which two organism mutually benefit from each other
mutualism
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is a symbiotic relationship in which two species benefit from the relationship without harming or benefiting the others
commensalism
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is a symbiotic relationship where one organism is benefited at the expense of the other
parasitism
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artificial environmental with many organism living together
biofilm
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is the measure of the pathogenicity of an organism. is the relative ability of a microorganism to cause disease or the degree of pathogenicity
virulence
66
factors that are produced by a microorganism and evoke disease
virulence factors
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virulence factors helps the bacteria to:
invade the host cause disease evade host defenses
68
many pathogenic bacteria colonize mucosal sites bt using pili to adhere to cells
adherence factors
69
surface components that allow the bacterium to invade host cells can be encoded on plasmids, but more often are on the chromosome
invasion factors
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skin, flushing of the urine, structures of body openings
physical barriers
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cough, sneeze reflex
cleansing mechanism
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lysozymes target the cell wall of bacteria
antimicrobial substances
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organism that are normally present in some specific areas of the body
indigenous/ normal flora
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inhabit and multiply months to year
resident
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inhabit but does not multiply short period of time
transient
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(specific resident flora) mouth and oral cavity
viridans streptococci
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(specific resident flora) upper respiratory tract
viridans strep, staph epidermins, dephtheroids
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(specific resident flora) nasopharynx
s. aureus, s epidermis, n. miningitidis
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(specific resident flora) colon
e. coli. bacteroides, lactobacillus
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(specific resident flora) urethra
diphtheroid, s. epidermis, and non hemolytic strep
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engulfment of infective agent by a phagocyte
phagocytosis
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capable of engulfing bacteria
neutrophil, monocytes, macrophages, mast cell, natural killing cells
83
due to population of rbcs in the area. responce of the red blood cells
rubor or redness
84
due to the capillary liquid homeostasis via the action of serum proteins
tumor or swelling
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due to the tumor necrosis factors via the rbcs
calor or heat
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due to the pressure of nerve endings cuases by swelling
dolor or pain
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unseuccessful inflamatory response
functio laesa or loss or function
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ability of the host to mount specific response
immune response
89
two types of toxins
exotoxins and endotoxins