Specify relevance of opioid analgesics and antagonist : A) antagonist B) agonist 1: remifentanil 2:oxycodone 3:naloxone 4:butorphanol 5:naltrexone

Drug used in insomnia and epilepsy: 1:Diazepam 2:Lamotrigine 3:Phenobarbital 4:Carbamazepine 5:Brivaracetam

Typical for caffeine:

Use for treatment of depression:

Antidepressant blocking serotonin-norepinephrine reuptake:

Psychostimulant is antagonist of endogenous adenosine:

It is not typical for Amphetamine:

Not a mechanism of action of Methylxanthines:

It is not psychostimulant:

Specify relevance: 1) Psychostimulant - Hydroxyzine 2) Anesthetic - Etomidate 3) Opioid - Levorphanol 4) Antipsychotic - Modafinil 5) Anxiolytic - Buspirone

Actions, not typical for Methylxanthines: 1) Mild diuretic action 2) Stimulation the chemoreceptor trigger zone 3) Stimulation of secretion of gastric acid 4) Relaxation the smooth muscles of the bronchioles 5) Depression of cough center

Antidepressant inhibiting selective serotonin reuptake:

Tricyclic antidepressant:

Monoamine oxidase inhibitors:

Specify relevance: 1) Antidepressant - Maprotiline 2) Anesthetic - Gabapentin 3) Psychostimulant - Thioridazine 4) Antipsychotie - Trifluoperazine 5) Anxiolytic - Triazolam

Clozapine has high affinity for: 1) 5-HT1a receptors 2) D4 receptors 3) 5-HT2 receptors 4) D2 receptors 5) alpha adrenoreceptors 6) D1 receptors

Correct statements: 1) Buspirone have affinity for serotonin receptors 2) Barbiturates inhibits cytochrome Pass microsomal enzymes in the liver 3) Zolpidem binds to GABA, receptors 4) Ramelteon is selective antagonist at the MTi and MTa melatonin receptors 5) Benzodiazepines acts on the ion channel of GABA

Analgesic caused pupil contraction, vomiting, and constipation:

Which type of receptors blockade Naloxone?

Typical for Carbidopa:

Does not possess antiepileptic activity:

Second-generation antipsychotics: 1) Risperidone 2) Molindone 3) Clozapine 4) Loxapine 5) Olanzapine 6) Quetiapine

First-generation antipsychotic: 1) Haloperidol 2) Pimozide 3) Cariprazine 4) Chlorpromazine 5) Thiothixene 6) Risperidone

Antagonists of opioid receptors:

The correct answer.

Anti-Parkinson drugs inhibiting cholinergic eftects:

Carbidopa: 1) Does not cross the BBB 2) Crosses the BBB 3) Inhibits dopamine decarbosylase in the brain 4) Inhibits dopamine decarboxylase in peripheral tissu 5) Increase effects of levodopa 6) Decrease effects of levodopa

Ropinirole is:

Anti-Parkinson drug, which is contraindicated in Parkinson patients with close angle glaucom:

Is not typical for Selegiline:

Untypical for second-generation antipsychotic:

Anti-Parkinson drugs: 1) Dopamine receptor agonists 2) Cholinergic antagonist 3) Dopamine receptor antagonist 4) Cholinergic agonists

Is not "Morphine-like" effect:

Opioid analgesics:

Specify relevance A) Selective serotonin reuptake inhibitors B)Serotonin-norepinephrine reuptake inhibitors 1) Fluoxetine 2) Sertraline 3) Duloxetine 4) Venlafaxine 5) Fluvoxamine 6) Levomilnacipran

Specify relevance: A)Tricyclic antidepressants B) Serotonin-dopamine antagonists 1) Quetiapine 2) Aripiprazole 3) Amitriptyline 4) Clomipramine 5) Amoxapine 6) Brexpiprazole

Specify relevance of antiparkinsonian agents: A) MAO-B inhibitors B) COMT inhibitors 1) Entacapone 2) Safinamide 3) Selegiline 4) Carbidopa

Specify relevance of antiparkinsonian agents: A) Dopamine receptor agonists B) Antimuscarinic agents 1) Benztropine 2) Apomorphine 3) Trihexyphenidyl 4) Ropinirole 5) Bromocriptine

Correct statement: 1) Topiramate is used in status epilepticus 2) Lamotrigine stimulates sodium channels 3) Tiagabine blocks GABA uptake into presynaptic neurons 4) Ethosuximide is most effective in treating absence seizures 5) Carbamazepine is benzodiazepine

Antiepileptic drugs that can be used for insomnia:

Specify relevance: A) Inhaled general anesthetics B) Intravenous general anesthetics 1) Methohexital 2) Propofol 3) Desflurane 4) Dantrolene 5) Nitrous oxide

Similarity of Propofol and Ketamine:

Specify relevance: A) Eszopiclone B) Midazolam 1) Nonbenzodiazepine derivative 2) Used for general anesthesia 3) Benzodiazepine derivative 4) Unpleasant taste on the mouth 5) Used for local anesthesia 6) Barbiturate derivative

Typical for benzodiazepines:

Specify relevance: A) Antagonists of opioid receptors B) Agonist-antagonists of opioid receptors 1) Naloxone 2) Pentazocine 3) Alfentanil 4) Naltrexone 5) Butorphanol

Antagonists of opioid recepters:

Effects of Butorphanol: 1) Weak psychotomimetic effects 2) Agonist of opioid receptors 3) Agonist-antagonist of opioid receptors 4) Antagonist of opioid receptors 5) Does not affect the heart

Specify relevance: A) Agonists of opioid receptors B) Agonist-antagonists of opioid receptors 1) Nalbuphine 2) Butorphanol 3) Naloxone 4) Buprenorphine 5) Alfentantl 6) Meperidine

Incorrect statement regarding Ketamine:

Incorrect statement regarding Propofol:

Partial agonists of the opioid receptors:

Buprenorphine is:

Incorrect statement regarding benzodiazepines:

Incorrect statement regarding benzodiazepines:

Specify relevance of receptors and drug: A) -U_opioid receptor B) D2-dopamine receptor C) Benzodiazepine BZ-receptor 1) Morphine 2) Diazepam 3) Chlorpromazine 4) Selegiline

Long-acting barbiturate:

False expression for barbiturates:

False expression for Phenobarbital:

Barbiturates mainly affect the system:

Does not refer to Isoflurane:

Not typical to benzodiazepines:

Not typical to barbiturates:

Does not refer to Morphine: 1) Increases the motility and decrease the tone of intestinal circular smooth muscle 2) Releases histamine from mast cells 3) Decreases the strength, duration, and frequency of uterine contractions 4) Causes antivomiting effect 5) Produces dilation of the pupil 6) Leads to opioid-induced androgen deficiency

Typical for Etomidate: 1) Has analgesic activity 2) May decreased plasma cortisol and aldosterone levels 3) Is short-acting 4) Has slowly induction 5) Weak effect on the heart and systemic vascular resistance

Benzodiazepine derivative used in anesthesiology:

Typical to Sevoflurane: 1) Has hypertension action 2) Has a long onset 3) Has low hepatotoxic potential 4) Has strong cardiotoxic potential 5) Has low respiratory imitation

Correct answers: 1) Propofol increases intracranial pressure 2) Etomidate has analgesic activity 3) Ketamine stimulates the heart with increased blood pressure 4) Midazolam has strong cardiovascular depressant effects 5) Thiopental may cause a reflex tachycardia

Inducers of microsomal enzymes

Typical for Isoflurane: 1) Increases the sensitization of myocardium to catecholamine action 2) Produces dose-dependent hypotension 3) Uses as an emulsion 4) Is a halogenated gas 5) Has hepatotoxic action 6) More comfortable for longer surgeries

Second messenger related receptors:

Part of Pharmacology, which study phannacological effects of drugs, as well as the mechanism of action of drug :

Enteral administration:

Pharmacokinetics not studying:

Officinal drugs are:

Magistral drugs are:

Determine the total volume of a 2% solution of pilocarpine hydrochloride per 100 doses for instillation of 2 drops 3 times a day into the conjunctival sac of the damaged eye (in ml):

Determine a single dose of Nitroglycerin for the taking of 1 drop on a piece of sugar under the tongue in 5 ml of 1% solution:

Epinephrine is.characterized by: 1) Bronchodilation 2) Increased peripheral resistance 3) Increased myocardial contractility 4) Decreased lipolysis 5) Reduced blood sugar

The cause of hyperglycemia caused by Epinephrine: 1) Decrease in insulin secretion as aresult of activation of Bi-adrenergic receptors 2) Increased muscle and liver glycogenolysis due to stimulation of B2-adrenergic receptors 3) Increased release of glucagon by activation of Br-adrenergic receptors 4) Inhibition of insulin release as a result stimulation of az-adrenergic receptors 5) Increased glycogen synthesis as a result of stimulation of a-adrenergic receptors

Correct statement: 1) Phenylephrine is.used in the treatment of hypertension. 2) Propranolol is used in the treatment of bronchial asthma. 3) Terbutaline is used, for pheochromocytoma. 4) Prazosin is used as an antihypertensive agent. 5) Tamsulosin is used for prostatic hyperplasia.

Determine compliance: A) Causes hypertension B) Causes hypotension 1) Epinephrine 2) Atenolol 3) Propranolol 4) Dobutamine 9) Ephedrine

Adrenomimetics are characterized by: 1) Increased intraocular fluid production 2) Stimulates glycogenolysis 3) Increased closure of the bladders sphincter 4) Stimulates lipolysis 5) Increased muscle tone of the bronchi

Determine the conformity: A). Phenylephrine B) Carvedilol 1) Leads to hypotensive effect 2) Leads to hypertensive effect 3) Causes orthostatic hypotension 4) Causes vasoconstrictor effect 5) Decreases lipid peroxidation

Epinephrine, unlike Phenylephrine, causes: 1) Increased blood pressure 2) Decreased intraocular pressure 3) Causes tachycardia 4) Cause vasoconstrictor effect 5) Causes bronchodilation

Epinephrine, unlike Phenylephrine, causes: 1) Vasoconstriction 2) Hypertensive effect 3) Decreased intraocular pressure 4) Hyperglycemia 5) Bronchial dilation

Determine the conformity: A) Stimulates B-adrenergic receptors B)Stimulates a-adrenergic receptors 1) Oxymetazoline 2) Terbutaline 3) Epinephrine 4) Clonidine 5) Isoproterenol

Determine the conformity: A) Phenylephrine B) Reserpine 1) Reduces blood pressure 2) Increases blood pressure 3) Blocks transport of norepinephrine from the cytoplasm into storage vesicles 4) Indicated in agitated psychotic states 5) Reduces intraocular pressure

Pilocarpine, unlike Timolol: 1) Used in acute attack of glaucoma 2) Changes focus to near vision 3) Effective in diminishing intracular pressure 4) Used topically in the treatment of glaucoma 5) Changes pupil size

Epinephrine, unlike Norepinephrine, causes: 1) Hypertension 2) Decrease in intraocular pressure 3) Increase in glycogenolysis in muscles and the liver 4) Bronchial dilatation 5) Vasoconstriction

Drug contraindicated in bronchial asthman

Determine the conformity: A) Reserpine B)Ephedrine 1) Acts on release of stored norepinephrine from nerve endings 2) Used to treat hypertension 3) Raises systolic and diastolic blood pressures 4) Relieves symptoms of psychotic arousal in schizophrenia 5) Produces a mild stimulation of the CINS

Anticholinesterase agent:

The reason for the increase in intraocular pressure after M-cholinoblockers:

M-cholinomimetics: 1) Reduces intracular pressure 2) Causes tachycardia 3) Increases gastrointestinal motility 4) Causes bronchodilator efiect 5) Reduces salivation

The mechanism of action of Procaine:

Mechanism of action of Mepivacaine:

For Pilocarpine is not typical:

Memantine is characterized by: 1) Is plant origin 2) Used for Alzheimer disease 3) Used for bronchial asthma 4) Is an NMDA receptor antagonist 5) Selective agonist of M-cholinergic receptors

Used for poisoning with organophosphorus compounds: