問題一覧
1
A procedure that involves washing a newborn's eyes with a 1% Silver nitrate to prevent ophthalmia neonatorum of N. gonorrheae
Crede's prophylaxis
2
Transmission-based Isolation Recommendations for Airborne precautions (Chicken pox, Shingles, Measles; N95 respirator: TB, SARS, Avian Influenza (H5-H10)
Negative pressure; Fluid-resistant mask and eye protection
3
Bioindicators for gas sterilant or ethylene oxide
Bacillus subtilis, Bacillus athrophaeus
4
Minimum required BSC for BSL-III
BSC-II
5
Autoclave settings for medical waste w/ blood/bloody fluids; Best sterilization and decontamination of used media
132°C; 15 psi, 30-60 mins
6
It requires on-site preparation; economical alternative to expensive antiseptics; used in cleaning of chronic wounds prior to administration of antibiotics
Hypochlorous acid + chlorine
7
Emerging/Recurrent; Could be engineered in the future
Category C bioterrorism agents
8
And oxidizing agent: Used in sterilizing HEPA filter in BSCs, metals, and medical instruments like scissors; No toxic by-product
Vapor-Phase hydrogen peroxide
9
BSL - III risk description
causes serious or deadly disease; treatment or prevention may or may not be available
10
There should be ____ feet around the bsc during operation to ensure the proper air circulating system
3
11
Highest risk; Easily transmitted; Highly Infectious
Smallpox, B. anthracis, Y. pestis
12
Tyndallization/Fractional sterilization is a process that happens for 3 consecutive days. It kills ___ on the 1st day, ___ on the second say, and ___ on the 3rd day.
vegetative cells; spores, the remaining cells
13
Physical methods of disinfection: Batch method
63°C; 30 min
14
Examples of biosecurity
Personnel security (access controls) , Physical security (CCTV, password-protected doors) , Material control, Quarantine, Policy
15
Recommended sterilization for Lowenstein Jensen
Inspissation
16
For instances in which the agent is highly transmissible like a person under investigation (PUI) or confirmed for ebola virus, an outer apron may not be necessary.
True
17
Iodine + alcohol
Tincture of iodine
18
Used in benchtops or surfaces, floors, furniture and walls. It is activated by organic compounds; non-tuberculoidal, non-sporocidal
Quaternary Ammonium Compounds (QUATS)
19
Protect the people from germs
biosafety
20
LRN that detects and recognizes a possible bioterrorism event. Formerly Level A laboratories
Sentinel Lab
21
70% recirculated; 30% exhausted
BSC-II A1
22
Most common concentration of Sodium hypochlorite (house bleach)
5.25-6.15% NaOCl
23
Same as gluteraldehyde but more stable and requires no activation; does not require exposure monitoring and not mucus membrane irritant
Ortho-Phthalaldehyde (OPA)
24
Inceneration temperature
870-980°C
25
Treat all human blood and certain body fluids as infectious for bloodborne pathogens (hiv, hbv, etc)
universal precaution
26
Resistant to Alcohol disinfection
Enterococcus faecium
27
Has high antimicrobial activity, better than povidone iodine, and has low toxicity. More effective on gram+ than gram-. Less effective in fungi and mycobacteria; baked viruses are not in activated.
Chlorhexidine gluconate (CHG)
28
BSL - IV risk description
High individual and community risk
29
Physical methods of disinfection: Boiling
100°C; 15 min
30
Inspissation settings
70-80°C; 2 hours 3 consecutive days
31
Transmission-based Isolation Recommendations for Contact Precautions (MDR bacterial infections, Adenovirus, Diarrhea and GI infections, Hepa A, Herpes simplex, Lice, Scabies; Mask if with respiratory: Parainfluenza, RSV, Chickenpox)
None
32
Examples of biosafety
Spill kit, Engineering controls (BSC, Fume hoods) , Sterilisation , Disinfection , Isolation techniques
33
Protect the germs from people
biosecurity
34
Tincture of Iodine and Iodophore are examples of
Halogen
35
BSL - I risk description
No or low individual and community risk
36
For heat-sensitively materials; most common gas sterilant
Ethylene Oxide (ETO)
37
Bioindicators for dry heat/oven
Bacillus subtilis, Bacillus athrophaeus
38
Former name of Bacillus athrophaeus
Bacillus subtilis var. niger, Bacillus subtilis var. globigii
39
No air recirculation; total exhaust to the outside
BSC-II B2
40
Contact time for iodophore in drawing blood culture and surgery
>30 seconds
41
Concentration of Hydrogen Peroxide in Catalase test
3%
42
For drying glassware, cotton swab, oils, petrolatum, powder
Oven
43
BSL - II risk description
Moderate individual and low community risk
44
HEPA filter size and efficiency
0.3 um; 99.995%
45
BSC class with Vertical Laminar flow
BSC-II
46
Substitute for 1% Silver nitrate in performing Crede's prophylaxis
Erythromycin or povidone iodine
47
Containment principles and practices to prevent unintentional exposure to pathogens and toxins or their unintentional release
biosafety
48
Halogen-substituted phenolic compound
Chloroxylenol
49
When dealing with spillage, it is necessary to Adsorp with paper towel first before neutralizing
True
50
It acts as a membrane when pulling liquids with a vacuum in the Membrane Filtration sterilization process
Cellulose acetate
51
BSC class for Research facilities
BSC-III
52
Physical disinfection method used in working surfaces of BSC and contaminated rooms
Non ionizing radiation
53
Oven temp and time
160-170°C; 1.5-3 hours
54
Sodium hypochlorite dilution according to CDC recommended for cleaning tabletop after blood spills
1:10
55
70% ethyl alcohol followed by iodophor is used in drawing blood culture and surgery
True
56
Used in sterilizing disposable such as plastic syringe, vacutainer, blood tubes, catheters and gloves
Ionizing/Gamma Radiation
57
Physical methods of disinfection: Flash method
72°C; 15 sec
58
Spillage
Wear PPE, Adsorb with paper towel, Neutralize with disinfectant (10% bleach) , Dispose in yellow bag
59
Transmission-based Isolation Recommendations for Droplet Precautions (Pertussid, Influenza, Neisseria meningitidis is and other bacterial meningitidis, Cocksackie, RSV, mumps, Rubella)
Fluid-resistant mask and eye protection
60
Sporicidal in medical equipment in 3-10 hours; does not corrode lens, metal, rubber, bronchoscope
Glutaraldehyde
61
Stable, biodegradable and active in the presence of organic materials. Can be found in germicidal soap
Ortho-phenylphenol and Ortho-benzyl-para-chlorophenol
62
Killing pathogenic microbes but not necessarily all microbes, prions and spores
Disinfection
63
30% recirculated; 70% exhausted
BSC-II B1
64
Certification of biosafety cabinet should be done after
All of the choices
65
Laboratory response network responsible for definitive characterization of agents
National Laboratories
66
Which of the following can be used for disinfecting BSC hoods when in gas form
Formaldehyde
67
Protection and control for biological materials to prevent their unauthorized access, loss, theft, diversion, or intentional release
Biosecurity
68
For outbreaks of gram+ infections
Hexachlorophene
69
Moderately easy to transmit; Moderate to Low mortality
B. pseudomallei, Brucella, C. perfringens toxins
70
Effective even in the presence of organic material; used in surface sterilization of surgical instruments; kills bacteria, fungi and even their spores
Peracetic acid + Hydrogen peroxide
71
Removal of pathogenic microbes in inanimate objects so that they are safe to handle and dispose
decontamination
72
BSL - III risk description
High individual and low community risk
73
Apply only to blood and all body fluid or secretions except sweat, non intact skin and mucous membrane
Standard precaution
74
Moderately easy to transmit; Moderate to Low mortality
Category B bioterrorism agents
75
70% recirculated; 30% exhausted; has 100 LFM
BSC-II A2
76
Highest risk; Easily transmitted; Highly Infectious
Category A bioterrorism agents
77
Required BSC for BSL-II
BSC-II
78
Autoclave, Tyndalization/Fractional sterilization and Inspissation are types of sterilization method under
Moist heat
79
Modification of UP- treat all as infectious
body substance isolation
80
Properly pasteured milk should have a
Negative ALP test result
81
Kills bacteria, mycobacteria, virus, fungi. It is not sporicidal
Ethyl alcohol
82
BSL - IV risk description
causes serious or deadly disease; treatment or prevention is usually not available
83
Added to many household products; clothing kitchenware toothpaste and toys to prevent bacterial contamination
Triclosan
84
Iodine + neutral polymer (Povidone-iodine, Poloxamer-iodine)
Iodophor
85
Bioindicators for Autoclave
Geobacillus stearothermophilus
86
Has the reagents and technology for confirmatory testing of pathogens
Reference Lab
87
Required BSC for BSL-I
None
88
Meaning of HEPA
high efficiency particulate air
89
Physical methods of disinfection: Bailey's
70°C; 30 min
90
Bioindicators for radiation
Bacillus pumilus
91
Principle: generates plasma by exciting the gas in enclosed chamber under deep vacuum with the use of radio frequency or microwave energy
Hydrogen peroxide gas plasma
92
Emerging/Recurrent; Could be engineered in the future
Ebola, Dengue, MERS-CoV, Hemorrhagic fever Viruses
93
Autoclave settings for sterilising broth and media
121°C; 15 psi, 15-30 min
94
Killing all forms of microbial life including spores
sterilization
95
BSL - II risk description
can cause disease but rarely severe; with available treatment or prevention
96
Concentration of Hydrogen Peroxide in Superoxol test
30%
97
Required BSC for BSL-IV
BSC-III or in full-body positive pressure suite