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問題一覧
1
antagonism tha has different receptors- opposite effect
physiologic
2
1+0=2 inactive drug enhances the effect of the active drug
potentiation
3
celebrex
celecoxib
4
a selective cox2 inhibitor that causes increased risk of cardiovascular events, and GI bleeding or ulceration
celecoxib
5
symptoms include dizziness, vertigo, tinnitus
meniere's disease
6
parenterally administered vasodilator for hypertensive emergencies and severe heart failure
sodium nitroprusside
7
levophed
norepinephrine
8
the immunoglobin present in the first breastmilk of a mother known as colostrum
IgA
9
AE of warfarin
fetal warfarin syndrome, nasal hypoplasia
10
ezetimibe+ simvastatin
vytorin
11
trimethoprim+ sulfamethoxazole
bactrim
12
anti-viral + anti parkinsons disease
amantadine
13
levodopa+ carbidopa
sinemet
14
proven to occur in well-known studies
established
15
imipenem+ cilastin
primaxin
16
what type of antagonism if there is an alteration of chemical structure
chemical
17
form of IgA
dimer
18
a UTI patient has been unresponsive to ciprofloxacin therapy. which of the following drugs could the patient be concominantly taking with the antibacterial agent that decrease its efficacy
fluoroquinolones
19
iodine-induced thyrotoxicosis
jod-basedow phenomenon
20
1+1=2 sum of individual effects
additive
21
- a histamine analog used to improve blood circultion to the inner ear in menniere's syndrom
betahistine
22
refers to the psychological or physiological adaptations that occur in response to frequent administration of a drug
dependence
23
tetrahydrozoline causes what
vasoconstriction
24
autoimmune disorder - hyperthyroidism
grave's disease
25
the immunoglobin primarily found in the primary response of the adoptive immunity to an infection
IgM
26
pharmacodynamic interaction between Morphine + naloxone; heparin + protamine so4
antagonism
27
most common tendon rupture of fluoroquinolone
achilles tendon
28
autoimmune disorder- hypothyroidism
hashimoto's disease
29
electron donor- inhibits formation of free radicals
true antioxidants
30
immunoglobin found in bodily secretions
IgA
31
pharmacodynamic interaction between amoxicilin + clavulanic acid (amoclav); imipenem+ cilastin
potentiation
32
antihistamine+ sedative hypnotics=
additive sedation
33
could occur, but of limited date
possible
34
large amount of iodine - reduced thyroid levels
wolff-chaikoff effect
35
Histamine (H2- constrict) + epinephrine (B2- dilate); amphetamine (stimulant)+ phenobarbital (sedative) is what type of antagonism
physiologic
36
immunoglobin that is a receptor for b-cells
IgD
37
visine
tetrahydrozoline
38
pharmacodynamic interaction between alcohol + CNS depressant; ampalaya + antidiabetic drugs
additive
39
tetrahydrozoline is classified as an ________ preparation
opthalmic
40
hexetidine is what type of antiseptic
oral
41
the interaction of acacia with bismuth salts will lead to
cementation
42
adverse effect of vancomycin
red man syndrome
43
lasix
furosemide
44
form of IgM
pentameter
45
may occur but needs further study
suspected
46
sodium nitroprusside is administered via what route in treating hypertensive emergencies
parenteral
47
pharmacodynamic interaction between anti-TB drugs (RIPE); penicillins + aminoglycosides
synergism
48
local anesthetic + antiarrhythmic
lidocaine
49
tagamet
cimetidine
50
form of IgG, IgE, and IgD
monomer
51
what is most likely to occur when an anticoagulant is used concomitantly with antibiotic
bleeding
52
neutralization (i.e., heparin + protamine); chelation (i.e., calcium + edta) is what type of antagonism
chemical
53
other term of physiologic antagonism
functional
54
the imunoglobin primarily involved in anaphylactic and hypersensitivity reactions
IgE
55
atracurium is a __________ blbocker
neuromuscular
56
teratogenic effect of methadone
neonatal abstinence syndrome
57
1+1=3 joint effect > sum of individual effects
synergism
58
1+1+0 two drugs counteract the effect of each other
antagonism
59
adverse effect of insulin
hypoglycemia, weight gain
60
mineral chameleon+ glycerin; mineral chameleon + sugar
explosive combination
61
adverse effect of methyldopa
hemolytic anemia
62
nitrofurantoin and methenamine are what type of antiseptics
urinary
63
other term for antioxidant synergist
chelating agent
64
black box warning whem taking quinolones
tendinitis
65
BZD+ flumazenil (GABAa); morphine+ naloxone (mu opioid) is what type of antagonism
pharmacologic
66
why is the concomitant use of amphotericin b wih aminoglycosides not advisable
both are nephrotoxic
67
teratogenic effect of carbamazepine
neural tube defect
68
r-thalidomide (anti nausea) and s-thalidomide (teratogen) ais what type of chemical incompatibility
racemization
69
the use of atropine to suppress the muscarinic effects of excess acetylcholine consequent to the use of neostigmine is an exa,ple of what type of antagonism
pharmacologic
70
these are reactions that are noxious, unintended, and which occur at doses normally used in man for prophylaxis, diagnosis, or therapy
adverse drug reaction
71
this is a phenoenon wherein the response to a substance is decreased with continuous use of the same dose of that substance
tolerance
72
doubtful, no clinical evidence
unlikely
73
chemical incompatibility of formaldehyde- paraformaldehyde (retarded by methanol)
polymerization
74
increase activity of antioxidants
antioxidant synergist
75
anti epileptic + anti arrhythmic
phenytoin
76
the change in color of epinephrine from a clear solution to a brown coloration is a result of
oxidation
77
used for smoking cessation
varenicline
78
most stable form of cocoa butter
beta
79
immunoglobin that is most abundant in infants- placental passage
IgG
80
povidone-iodine is what type of antiseptic
wound
81
which erythromycin salt causes cholestatic jaundice
estolate
82
drug that initiates the interaction
precipitant
83
antagonism that has that has same receptors- inhibition of effects
pharmacologic
84
oxidizing agents are incompatible with reducing agents. this is an example of what incompatibility
chemical
85
levodopa+ carbidopa+ entacapone
stalevo
86
it causes systemic lupus erythematosus
hydralazine
87
hormones and neurotransmitters in adrenal medulla
NE, epi
88
very likely but not proven clinically
probable
89
what drug has the brand name Alli
orlistat