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問題一覧
1
visine
tetrahydrozoline
2
tetrahydrozoline is classified as an ________ preparation
opthalmic
3
tetrahydrozoline causes what
vasoconstriction
4
sodium nitroprusside is administered via what route in treating hypertensive emergencies
parenteral
5
parenterally administered vasodilator for hypertensive emergencies and severe heart failure
sodium nitroprusside
6
nitrofurantoin and methenamine are what type of antiseptics
urinary
7
hexetidine is what type of antiseptic
oral
8
povidone-iodine is what type of antiseptic
wound
9
anti-viral + anti parkinsons disease
amantadine
10
local anesthetic + antiarrhythmic
lidocaine
11
anti epileptic + anti arrhythmic
phenytoin
12
- a histamine analog used to improve blood circultion to the inner ear in menniere's syndrom
betahistine
13
symptoms include dizziness, vertigo, tinnitus
meniere's disease
14
atracurium is a __________ blbocker
neuromuscular
15
used for smoking cessation
varenicline
16
the immunoglobin primarily found in the primary response of the adoptive immunity to an infection
IgM
17
form of IgM
pentameter
18
the imunoglobin primarily involved in anaphylactic and hypersensitivity reactions
IgE
19
the immunoglobin present in the first breastmilk of a mother known as colostrum
IgA
20
form of IgA
dimer
21
form of IgG, IgE, and IgD
monomer
22
immunoglobin that is most abundant in infants- placental passage
IgG
23
immunoglobin that is a receptor for b-cells
IgD
24
immunoglobin found in bodily secretions
IgA
25
tagamet
cimetidine
26
what type of antagonism if there is an alteration of chemical structure
chemical
27
antagonism that has that has same receptors- inhibition of effects
pharmacologic
28
antagonism tha has different receptors- opposite effect
physiologic
29
levophed
norepinephrine
30
the use of atropine to suppress the muscarinic effects of excess acetylcholine consequent to the use of neostigmine is an exa,ple of what type of antagonism
pharmacologic
31
trimethoprim+ sulfamethoxazole
bactrim
32
neutralization (i.e., heparin + protamine); chelation (i.e., calcium + edta) is what type of antagonism
chemical
33
BZD+ flumazenil (GABAa); morphine+ naloxone (mu opioid) is what type of antagonism
pharmacologic
34
Histamine (H2- constrict) + epinephrine (B2- dilate); amphetamine (stimulant)+ phenobarbital (sedative) is what type of antagonism
physiologic
35
other term of physiologic antagonism
functional
36
ezetimibe+ simvastatin
vytorin
37
1+1+0 two drugs counteract the effect of each other
antagonism
38
1+0=2 inactive drug enhances the effect of the active drug
potentiation
39
1+1=3 joint effect > sum of individual effects
synergism
40
1+1=2 sum of individual effects
additive
41
imipenem+ cilastin
primaxin
42
pharmacodynamic interaction between Morphine + naloxone; heparin + protamine so4
antagonism
43
pharmacodynamic interaction between amoxicilin + clavulanic acid (amoclav); imipenem+ cilastin
potentiation
44
pharmacodynamic interaction between anti-TB drugs (RIPE); penicillins + aminoglycosides
synergism
45
pharmacodynamic interaction between alcohol + CNS depressant; ampalaya + antidiabetic drugs
additive
46
levodopa+ carbidopa+ entacapone
stalevo
47
levodopa+ carbidopa
sinemet
48
a UTI patient has been unresponsive to ciprofloxacin therapy. which of the following drugs could the patient be concominantly taking with the antibacterial agent that decrease its efficacy
fluoroquinolones
49
celebrex
celecoxib
50
a selective cox2 inhibitor that causes increased risk of cardiovascular events, and GI bleeding or ulceration
celecoxib
51
autoimmune disorder - hyperthyroidism
grave's disease
52
large amount of iodine - reduced thyroid levels
wolff-chaikoff effect
53
autoimmune disorder- hypothyroidism
hashimoto's disease
54
iodine-induced thyrotoxicosis
jod-basedow phenomenon
55
lasix
furosemide
56
why is the concomitant use of amphotericin b wih aminoglycosides not advisable
both are nephrotoxic
57
antihistamine+ sedative hypnotics=
additive sedation
58
what is most likely to occur when an anticoagulant is used concomitantly with antibiotic
bleeding
59
black box warning whem taking quinolones
tendinitis
60
most common tendon rupture of fluoroquinolone
achilles tendon
61
what drug has the brand name Alli
orlistat
62
most stable form of cocoa butter
beta
63
the interaction of acacia with bismuth salts will lead to
cementation
64
the change in color of epinephrine from a clear solution to a brown coloration is a result of
oxidation
65
oxidizing agents are incompatible with reducing agents. this is an example of what incompatibility
chemical
66
proven to occur in well-known studies
established
67
very likely but not proven clinically
probable
68
may occur but needs further study
suspected
69
could occur, but of limited date
possible
70
doubtful, no clinical evidence
unlikely
71
drug that initiates the interaction
precipitant
72
electron donor- inhibits formation of free radicals
true antioxidants
73
increase activity of antioxidants
antioxidant synergist
74
other term for antioxidant synergist
chelating agent
75
chemical incompatibility of formaldehyde- paraformaldehyde (retarded by methanol)
polymerization
76
mineral chameleon+ glycerin; mineral chameleon + sugar
explosive combination
77
AE of warfarin
fetal warfarin syndrome, nasal hypoplasia
78
r-thalidomide (anti nausea) and s-thalidomide (teratogen) ais what type of chemical incompatibility
racemization
79
adverse effect of insulin
hypoglycemia, weight gain
80
teratogenic effect of methadone
neonatal abstinence syndrome
81
teratogenic effect of carbamazepine
neural tube defect
82
adverse effect of vancomycin
red man syndrome
83
adverse effect of methyldopa
hemolytic anemia
84
it causes systemic lupus erythematosus
hydralazine
85
which erythromycin salt causes cholestatic jaundice
estolate
86
hormones and neurotransmitters in adrenal medulla
NE, epi
87
refers to the psychological or physiological adaptations that occur in response to frequent administration of a drug
dependence
88
this is a phenoenon wherein the response to a substance is decreased with continuous use of the same dose of that substance
tolerance
89
these are reactions that are noxious, unintended, and which occur at doses normally used in man for prophylaxis, diagnosis, or therapy
adverse drug reaction