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Medical Microbiology (Lec) 1 part 2
  • Jessa Sumalde

  • 問題数 83 • 9/5/2023

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  • 1

    Causative agent of Lyme disease

    Borellia (Boreliella)

  • 2

    Arrangement of bacteria in pairs is also known as

    Diplococci

  • 3

    Arrangement of bacteria in single is also known as

    Monococci

  • 4

    Arrangement of bacteria is chains is also known as

    Streptococci

  • 5

    Arrangement of bacteria in cluster is also known as

    Staphylococci

  • 6

    8-membered cocci formation of bacteria

    Sarcina

  • 7

    Comparison of the Cytoplasmic membrane of bacteria, eukarya, and archeae

    In contrast to the lipids of the bacteria and eukarya in which ester linkages bond fatty acid to glycerol, the lipids of archaea contain either bands between glycerol and its hydrophobic side chains.

  • 8

    The membrane structure of archaea may be

    Bilayer, monolayer, or both

  • 9

    Are extremely resistant (R) to heat. Therefore, widely distributed among hyperthermophilic archaea

    Monolayer

  • 10

    Organisms that grow best at temperatures above ↑ 80 °C

    Hypothermophilic archaea

  • 11

    All bacteria have a cell wall composed of peptidoglycan except

    Mycoplasma

  • 12

    Petidoglycan is made up of

    Sugar backbone (glycan) + peptide side chains (peptido) cross-linked by transpeptidase

  • 13

    Rigid layer is a polysaccharide composed of 2 sugar derivatives

    N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)

  • 14

    Rigid layer is also composed of a few amino acids

    L-alanine, D-alanine, D-Glutamic Acid, either L-lysine or structural similar molecule Diaminopimelic acid (DAP)

  • 15

    Facilitate passage of small, hydrophilic molecules into the cell.

    Porin proteins

  • 16

    In the outer membrane of gram-negative bacteria → channels allow the entry of essential substances such as

    Sugars, amino acids, vitamins and metals as well as many antimicrobial drugs such as Penicillins

  • 17

    Example of Gram-negative bacteria

    Salmonella, Shigella, E-coli

  • 18

    Most common cause of Urinary tract infection

    E-Coli

  • 19

    Has small amounts of peptidoglycan in the cell wall

    Gram-negative bacteria

  • 20

    Has several sheets of peptidoglycan stacked from one another

    Gram-positive bacteria

  • 21

    Its cell wall mostly consists of outer membrane called lipopolysaccharide (LPS)

    Gram-negative bacteria

  • 22

    Does not contain outer membrane

    Gram-positive bacteria

  • 23

    Gram staining Mnemonics

    V - Violet/Crystal Violet (primary stain) I - Iodine (mordant) A - Alcohol (decolorizer) S - Safranin (secondary stain)

  • 24

    Has thicker and multilayer peptidoglycan layer

    Gram-positive bacteria

  • 25

    Has thinner peptidoglycan layer

    Gram-negative bacteria

  • 26

    Has teichoic acid in its layer

    Gram-positive bacteria

  • 27

    Has lipopolysaccharide and periplasmic space in its layer

    Gram-negative bacteria

  • 28

    Outer membrane of gram-negative bacteria contains

    Endotoxin known as Lipopolysaccharide (LPS)

  • 29

    All gram positive bacteria have NO ENDOTOXIN EXCEPT FOR

    Listeria monocytogenes

  • 30

    Are absent from the cell walls of Archaea.

    Peptidoglycan and an outer membrane

  • 31

    A variety of cell wall types are found in Archaea including those that contain

    Polysaccharides, proteins, glycoproteins

  • 32

    The backbone of pseudomurein is formed from the alternating repeats of

    → N-acetylglucosamine and → N-acetyltalosaminuronic acid

  • 33

    Cell wall of some archaea lacks pseudomurein and instead contain other polysaccharides like in cases of methanosarcina sp. they contain

    Glucuronic acid, galactosamine, uronic acid, acetate

  • 34

    Lipoprotein bilayer without sterols

    Cytoplasmic membrane

  • 35

    Site of oxidative and ETC enzymes

    Cytoplasmic membrane

  • 36

    Serves as a permeability barrier

    Cytoplasmic membrane

  • 37

    Prevent passage of leakage of solutes into and out of the cell

    Cytoplasmic membrane

  • 38

    Prevent passage of leakage of solutes into and out of the cell

    Cytoplasmic membrane

  • 39

    The membrane is an anchor for many proteins some of this are enzymes that function in the energy conservation and transport of solutes into and out of the cell

    Cytoplasmic membrane

  • 40

    Major site for energy conservation in the prokaryotic cell via the proton motive force

    Cytoplasmic membrane

  • 41

    RNA and protein in 50s and 30s subunits

    Ribosome

  • 42

    Major function is for protein synthesis

    Ribosome

  • 43

    Invagination of plasma membrane

    Mesosome

  • 44

    Participates in cell division and secretion

    Mesosome

  • 45

    Space between plasma membrane and outer membrane

    Periplasm

  • 46

    Contains many hydrolytic enzyme beta lactamases

    Periplasm

  • 47

    The enzyme periplasm contains

    Beta lactamases

  • 48

    Essential components of bacteria

    Cytoplasmic membrane, ribosome, mesosome, periplasm

  • 49

    Non essential components of bacteria

    Glycocalyx, flagella, pili, fimbriae, capsules

  • 50

    Mediates adherences to surfaces that acts as biofilms

    Glycocalyx

  • 51

    Two types of glycocalyx

    Slime layer, capsule

  • 52

    Loosely organized and attached

    Slime layer

  • 53

    Highly organized and tightly attached

    Capsule

  • 54

    Can be lost from the cell surface

    Slime layer

  • 55

    Adhere firmly to the cell wall and some are even covalently link to the petidoglycan

    Capsule

  • 56

    Common features of slime layer and capsule

    → Assist in the attachment of the bacterial cell to solid surfaces forming biofilms. → Act as virulence factors in certain bacterial diseases → Prevents the cell from dehydration

  • 57

    Many prokaryotes become motile via swimming through

    Flagella

  • 58

    Parts of the flagella:

    Filament, hook, basal body

  • 59

    Long, thin, helical structure composed of protein flagellin.

    Filament

  • 60

    Curved sheath

    Hook

  • 61

    Stacks of rings firmly anchored in cell wall.

    Basal body

  • 62

    Flagella can rotate

    360°

  • 63

    Responsible for the motility of the cell, and guide the direction of the bacteria in response to a stimulus

    Flagella

  • 64

    Chemical stimulus

    Chemotaxis

  • 65

    Light stimulus

    Phototaxis

  • 66

    Flagellar arrangements

    Monotrichous, lopotrichous, ampitrichous, peritrichous

  • 67

    Single flagellum at one end

    Monotrichous

  • 68

    Two flagellum each protruding from either ends of the cell.

    Ampitrichous

  • 69

    Small bunches of flagella emerging from one end

    Lopotrichous

  • 70

    Flagella is dispersed over the surface of the cell.

    Peritrichous

  • 71

    Filament of flagella is made up of protein

    Flagellin

  • 72

    Rigid tubular structure made of pilin proteins.

    Pili

  • 73

    Found only in gram-negative cells

    Pili

  • 74

    Functions to join bacterial cells for partial DNA transfer called conjugation.

    Pili

  • 75

    Partial DNA transfer

    Conjugation

  • 76

    Basically facilitates genetic exchange.

    Pili

  • 77

    Fine, proteinaceous, hairlike bristles emerging from the cell surface.

    Fimbriae

  • 78

    Extends from the cell surfaces, enabling cells to stick to surfaces and form pellicles (liquid) and biofilms (solid).

    Fimbriae

  • 79

    Function in adhesion to other cells and surfaces

    Fimbriae

  • 80

    All bacterial capsules are composed of polysaccharide except

    Bacillus anthracis (contain polypeptide D-glutamate)

  • 81

    Formed by gram-positive rods, only found in Bacillus and Clostridium spp

    Spore

  • 82

    Spore is formed by

    Gram-positive rods

  • 83

    Spore can only be found among

    Clostridium, Bacillus