問題一覧
1
Salivary gland secretion can be blocked by the administration of which of the following medications?
Atropine
2
Cyclic-3', 5'-AMP is broken down by which of the following?
Phosphodiesterase
3
What physiologic response occurs upon stimulation of the alpha-receptors?
Vasoconstriction
4
While making a routine home visit to a COPD patient, you notice that he appears very restless and irritable. He complains that he has been dizzy and nauseated and has been urinating frequently during the past 2 days. You review his medication list and see that he is prescribed aerosolized albuterol and Atrovent®, Serevent® by DPI, and Theobid®. You suspect that the patient is experiencing side effects from which of his medications?
Theobid
5
Of the following, which one would you anticipate to happen with parasympathetic stimulation?
Bronchoconstriction
6
A sympathomimetic is the same as an anticholinergic.
False
7
Which of the following describe(s) sympathomimetic bronchodilators? I. Drugs that stimulate intracellular production of cyclic AMP II. Anticholinergic drugs III. Drugs that stimulate beta2-receptors
I and III
8
Contraction of the bronchial smooth muscle is called which of the following?
Bronchospasm
9
The nickname “rest and digest” has been given to the _____ system.
Parasympathetic
10
Which of the following is TRUE regarding the length of the amine side chain of a medication? I. The longer the amine side chain, the less selective the medication is for a particular receptor. II. The shorter the amine side chain, the less selective the medication is for a particular receptor. III. The longer the amine side chain, the more selective the medication is for a particular receptor. IV. The shorter the amine side chain, the more selective the medication is for a particular receptor.
II and III
11
There are _____ mechanisms of bronchoconstriction.
3
12
A bronchodilator intended for long-term maintenance of asthma that does NOT have a rapid onset is _____.
salmeterol
13
Which of the following mechanisms does NOT cause bronchodilation?
Stimulating the conversion of cyclic AMP to GMP
14
The neurotransmitter of the parasympathetic system is acetylcholine.
True
15
Which are associated with the basic catecholamine molecule? I. Benzene ring II. Two hydroxyl groups III. Amine side chain
I, II, and III
16
Beta1-receptors are primarily located in the lungs.
False
17
Stimulation of what nervous system causes an increase in cardiac output, depth of ventilation, and metabolism?
Sympathetic system
18
Bronchospasm results from contraction of bronchial smooth muscle.
True
19
A patient is receiving beta2-agonist medications, corticosteroids, and a parasympatholytic agent. The physician has asked you to recommend a medication or classification of medications that could potentially help prolong the bronchodilatory effects of the beta2-agonists. Which of the following would you recommend?
Administration of a methylxanthine
20
Acetylcholine has a bronchoconstriction effect on bronchial smooth muscle.
True
21
Which of the following are considered to be hormonal in nature?
Catecholamine
22
Which of the following is a parasympatholytic?
Spiriva
23
Bronchoconstriction is caused by stimulation of which system?
Parasympathetic
24
All EXCEPT which of the following are possible disadvantages associated with administering drugs via inhalation?
There is a risk of increased systemic side effects.
25
Which of the following are advantages to drug administration via the inhalation route? I. Immediate onset of action at the desired site II. Smaller required doses III. Increased systemic drug absorption
I and II
26
Sympathetic stimulation results in bronchial smooth muscle contraction.
False
27
Which medication can be used to stop premature labor?
Magnesium
28
Beta1 stimulation can result in tachycardia.
True
29
Phosphodiesterase is inhibited by methylxanthines.
True
30
The mechanisms of bronchoconstriction are
Bronchospasm, Airway edema, Secretions
31
Why is it important to prevent anticholinergic medications from touching the eyes of individuals?
Increased intraocular pressure
32
Alpha-receptors are receptors of the sympathetic system.
True
33
Bronchoconstriction is characterized by an increase of the airway’s inner diameter.
False
34
When administering a beta2-agonist medication, you assess the patient’s vital signs before, during, and after treatment. Soon after beginning therapy, you realize that the patient’s HR is now 120, when it was 90 at rest prior to treatment initiation. Which of the following best describes the sequence of events you should now take? I. Terminate the treatment. II. Continue the treatment. III. Call the physician. IV. Continue to monitor the patient.
I, III, and IV
35
Which of the following nervous systems has been nicknamed the “fight-or-flight” system?
Sympathetic system
36
Ventolin is NOT short-acting beta-agonist.
False
37
When a patient experiences a decrease in response shortly after administration of a medication, they are experiencing which of the following?
Tachyphylaxis
38
An example of an anticholinergic is atropine.
True
39
Which of the following will allow for immediate effective evaluation of improvement of airway obstruction following administration of a bronchodilator?
PEFR
40
Beta2-receptor stimulation results in bronchial smooth muscle contraction.
True
41
Beta2-receptors are primarily located in the heart.
False
42
The sympathomimetic beta-agonist terbutaline is classified as a _____.
resorcinol
43
Which is NOT caused by the administration of a beta-agonist?
Salivation
44
Which is NOT a mechanism of bronchoconstriction?
Embolism formation
45
Which of the following is available as a DPI?
Tiotropium bromide
46
Which of the following is NOT a reason for toxicity resulting from theophylline?
A therapeutic level of 10 mcg/ml
47
Three different mechanisms cause bronchoconstriction.
True
48
Which medication is a resorcinol?
Metaproterenol
49
Acetylcholine is metabolized by acetylcholinesterase.
True
50
How are methylxanthines given?
Orally
51
What happens to the heart rate when the parasympathetic system is stimulated?
decreases heart rate
52
What enzyme breaks down cyclic AMP?
Phosphodiesterase
53
NE is the neurotransmitter at the postganglionic junction of the parasympathetic system.
False
54
In which of the following situations would you NOT use racemic epinephrine?
Acute bronchospasm
55
What classification of medication might you recommend for a patient with nonallergic rhinitis?
Anticholinergics
56
Which of the following receptors would be stimulated by norepinephrine?
Alpha receptors
57
An anticholinergic is a parasympatholytic.
True
58
Which receptor is found primarily in the lungs?
Beta2
59
You are called to the emergency room to treat an 18-year-old female who has been admitted in an acute asthma attack. She received two albuterol treatments prior to entering the emergency room. The patient’s breath sounds reveal wheezes bilaterally, and she is unable to perform a PEFR. Which of the following treatments would you recommend?
Continuous nebulization of albuterol
60
What is the mechanism of action of methylxanthine medications?
Inhibiting phosphodiesterase
61
Cyclic GMP causes bronchodilation.
False
62
Which nervous system causes bronchodilation of bronchial smooth muscle?
Sympathetic system
63
Stimulation of the alpha-receptor results in _____.
vasoconstriction
64
How is acetylcholine metabolized?
rapidly by acetylcholinesterase into choline and acetate
65
Which medication can also be given in the oral form?
Albuterol
66
In regard to duration of action, what type of beta-agonist are rescue inhalers considered?
Short acting Beta 2 Agonist (SABA)
67
Which of the following is NOT a SABA?
Foradil
68
For which neonatal condition is caffeine administered?
Apnea of prematurity
69
Which of the following systems is responsible for innervation of the bronchi? I. Autonomic nervous system II. Somatic nervous system III. Central nervous system
I only
70
Cyclic-3', 5'-AMP is broken down by Cyclic AMP phosphodiesterase.
True
71
Which of the following describe parasympatholytics? I. Drugs that stimulate the parasympathetic system II. Anticholinergic drugs III. Drugs that block acetylcholine
II and III
72
When side effects are a problem with the administration of albuterol, what alternative medication could you give to possibly prevent the onset of such side effects?
Levalbuterol
73
Bronchodilation is caused by stimulation of which system?
Sympathetic
74
A parasympatholytic agent has been administered. Which of the following physiologic effects would you expect to see in your patient? I. Constricted bronchial smooth muscle II. Decreased heart rate III. Increased blood pressure IV. Decreased salivation
III and IV
75
How is the sympathomimetic beta-agonist Xopenex® classified?
As a saligenin
76
Which medication should be given if suspected post-extubation airway edema is present?
Vaponefrin®
77
cAMP is believed to have anti-inflammatory properties and can prevent rupture of the mast cell by which of the following mechanisms?
Inhibition of calcium into the mast cell
78
Parasympathetic stimulation results in bronchial smooth muscle contraction.
True
79
A reduction in the inner diameter of the airway due to the influx of chemical mediators is best referred to as which of the following?
Inflammation
80
Serevent® is a long-acting beta-agonist.
True
81
Methylxanthines are strong bronchodilators.
False
82
A reduction in the inner diameter of the airway due to excessive mucus production is called _____.
secretion
83
The sympathetic system has been nicknamed the “rest-and-digest” system.
False
84
Which of the following is caused by the conversion of GTP to cGMP?
Constriction of bronchial smooth muscle
85
Atrovent® and albuterol together in MDI form is called _____.
Combivent
86
The “rest-and-digest” system is the parasympathetic system
True
87
Which of the following is the best course of action for a respiratory therapist when a patient is receiving a beta agonist medication and the initial HR was 85 bpm but shortly after the treatment begins, the HR increases to 120 bpm?
Stop the treatment, monitor the patient, and notify the physician.
88
A parasympatholytic will cause which of the following? I. Bronchodilation II. Decreased heart rate III. Drying of pulmonary secretions
I and III
89
The nickname “fight or flight” has been given to the _____ system.
Sympathetic
90
Which of the following drugs would be best used for maintenance of bronchospasm? I. Serevent® II. Spiriva® III. Theophylline
I and II
91
The administration of a _____ agent will stop or decrease the conversion of GTP to cGMP.
parasympatholytic
92
Stimulation of the alpha1-receptor results in vasoconstriction.
True
93
Which medication is a long-acting anticholinergic?
Tiotropium bromide
94
Alpha1-receptors are primarily located in the blood vessels.
True
95
A patient presents with dyspnea, increased work of breathing, shortness of breath, and a heart rate of approximately 145 bpm. The individual is 25 years old, has a 10-pack-a-year smoking history, and is otherwise healthy. Auscultation reveals diffuse expiratory wheezes bilaterally. You understand that the patient needs a beta2-agonist medication as a rescue medication, but you are fearful of the increase in heart rate associated with the administration of Ventolin®. Which of the following rescue beta2-agonist medications would you recommend to help reduce the cardiac side effects?
Levalbuterol