問題一覧
1
the initial, oxygen-independent stage of cellular respiration where glucose is broken down into pyruvate, producing ATP and NADH, and it occurs in the cytoplasm of all cells
glycolysis
2
is a series of catabolic reactions that extract energy from glucose by splitting it into two three-carbon molecules called pyruvates.
glycolysis
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Two phase of glycolysis
energy investment,energy payoff
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Phosphorylation of glucose and its conversion to glyceraldehyde 3-phosphate
energy investment
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Oxidative conversion of glyceraldehyde 3-phosphate to pyruvate and the coupled formation of ATP and NADH
energy payoff
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Location of glycolysis
cytosol
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Glycolysis can be
aerobic or anaerobic
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Complete rxn:
gluc+2nad++2adp+2pi~2pyruv+2nadh+2h++2atp+2h2o
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1st irreversible step in INVESTMENT PHASE
glucose phosphorylation
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Enzyme for glucose phosphorylation?
hexokinase
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Glucose phosporylation
to trap and activate glucose inside cell
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Preparation for succeeding glycolictic rxn
isomerization
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2nd irreversible step of energy investment
second phosporylation
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Enzyme of 2nd irreversible step
pfk-1
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Encloses the C-C cleavage products that are interconvertible
2nd irreversible step
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reverse rxn of aldol condensation
aldol cleavage
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To funnel single pathways
isomerization
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Required ATP per glucose of investment phase
2
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2 NADH per Glucose produced
phosphorylation coupled to oxidation
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2 ATP per Glucose produced
ATP generation/substrate level phosphorylation
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Activates the subsequent phosphoryl transfer
dehydration
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3rd irreversible step
2nd ATP gen
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How many ATP per gluc is required to 2nd ATP gen
2
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enzymes in 3rd irreversible step
pyruvate kinase
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Glycolysis produced how many ATP and NADH
2
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MANNOSE
Fructose 6-P
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GALACTOSE
Glucose 6-P
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FRUCTOSE IN LIVER
G3-P/DHAP