HEMATOLOGY

Yves Laure Pimentel · 70問 · 2年前

通報

問題一覧

Last coag factor in extrinsic and intrinsic pathway

Factor I

Last coag in extrinsic and intrinsic pathway

factor 2

Affected by coumadin

Factor VII

Factor Affected by coumarin

Factor VII

Affected by warfarin

Factor VII

Affected by brodifacoum

Factor VII

Affected by superwarfarin

Factor VII

The function of thromboplastin in the prothrombin test is to provide _____ to the assay

Phospholipoprotein

Not detected by PT or PTT

Platelet factor Factor XIII

LASER –

Light Amplified by Stimulated Emission of Radiation

Lifespan of platelet is

8 to 12 days/ 9 to 10 days

RBC transfusion is primarily to:

Increase Oxygen carrying capacity

Appropriate test for PNH

Sucrose hemolysis If may FLOW CYTOMETRY sa choices, then flow cytometry answer

X-linked or sex-linked hemophilia -> Occurs in MALE X chromosome

Hemophilia A Hemophilia B

FFP and CP are NOT USED in ANY platelet disorder example is ______

ITP

Unique to platelet

Open canalicular system

Immature RBC without nucleus

Reticulocytes

Migrate with Hemoglobin E

Hb C

Acute Hyperemia

Blushing

control of cellular function and transmission of genetic information

DNA

DNA Replication:

: S phase

: : S phase

DNA Replication

Division of the cellular cytoplasm

Cytokinesis

the cells produced contain 23 chromosomes

Meiosis

Meiosis the cells produced contain ? chromosomes

first inherited hematologic disorder to be diagnosed using molecular biologic assay

Sickle cell anemia

use to amplifies low levels of specific DNA sequences

PCR

considered to be the “gold standard” of molecular methods

DNA sequencing

cytokines for stem cell mobilization

GCSF and GM-CSF

Stem cell CD marker

CD34

Unstable Hb Portland 2 CONTAINS?

2 Zeta and 2 Beta

Unstable Hb 2 Zeta and 2 Beta

Portland 2

LOCATION OF TPO production

Liver

Liver ? production

TPO

PASSWORD CESS Increase platelet Increase WBC Increase cell inclusion Increase spherocytes

Splenectomy

Splenectomy Increases? (4)

Increase platelet Increase WBC Increase cell inclusion Increase spherocytes

the most frequently used site for bone marrow aspiration and biopsy

iliac crest

- bone marrow failure syndrome/empty and hypoplastic bone marrow

Aplastic Anemia

-failure to produce RBC, WBC, and platelets (pancytopenia)

Aplastic Anemia

-lymphocyte production is less affected

Aplastic Anemia

- is the drug most often implicated in acquired aplastic anemia

Chloramphenicol

- Chloramphenicol is the drug most often implicated in

acquired aplastic anemia

-decrease ESR

aplastic anemia

-JAK 2 mutation

Polycythemia vera

-Pancytosis (accd to Harr, it should be panmyelosis)

Polycythemia vera

-Increase ESR

Polycythemia vera

Polycythemia vera - ESR?

Increase

Aplastic Anemia - ESR?

decrease

-Increase RBC mass/count

Polycythemia

decrease Vit B12 or folate or both

Megaloblastic anemia

-Treatment with folic acid improves hematologic abnormalities but not neurologic problems

Megaloblastic anemia

Megaloblastic anemia -Treatment with ? improves hematologic abnormalities but not neurologic problems

folic acid

- – lack of castle intrinsic factor leading to LOW VIT B12 ABSORPTION

Pernicious anemia

-Pernicious anemia – lack of ? factor leading to LOW VIT B12 ABSORPTION

castle intrinsic

-parasite – causes Megaloblastic anemia, low Vit B12, Macrocytosis

D.latum

-D.latum – causes (3)

Megaloblastic anemia, low Vit B12, Macrocytosis

Hallmark of Megaloblastic anemia

Hypersegmented neutrophil

Hypersegmented neutrophil Hallmark of

Megaloblastic anemia

Hypersegmented neutrophil (nucleus ?)

greater than 6 lobes

Lab findings in Megaloblastic anemia

Ovalocytes and Pancytopenia

Differential test between Vit B12 deficiency and Folate deficiency

Serum methylmalonic acid

Differentiate between Vit B12 deficiency and Folate deficiency

Normal in folate def High in Vit B12 def

Beginning of Hb formation

Pronormoblast

first hemoglobin-synthesizing cell (hubbard)

Pronormoblast

Detectable of Hb synthesis

Basophilic normoblast

-Hemoglobin appears for the first time

Polychromatic normoblast

-the first stage in which the pink color associated with stained hemoglobin can be seen

Polychromatic normoblast

- Last stage capable of mitosis

Polychromatic normoblast

Last nucleated stage (RBC)

Orthochromic normoblast

is SLIGHTLY HIGHER in Polychromasia or reticulocytosis

MCV

MCV is SLIGHTLY HIGHER in ? or ?

Polychromasia or reticulocytosis

1. Numerous NRBCs 2. Pronounced POlychormasia 3. Decreased Hb and HCT

Red cell regeneration

Stain for Reticulocytes

Methylene blue

is used for Reticulocyte count

Miller disc

Miller disc is used for ?

Reticulocyte count

RBC characteristics um

6-8

RBC characteristics thickness

140 um2

RBC characteristics average volume

90fl

RBC characteristics color

Pink

RBC characteristics Pallor:

1/3 of the cell

RBC characteristics Average lifespan:

120 days

RBC characteristics Low RBC (only) with normal WBC and platelet

B ICE PAC Blackfan anemia/Congenital red Imperfecta/Chronic Cell aplasia/Joseph Diamond Erythroblastopenia/primary red Pure red cell anemia/Diamond Anemia/Erythrogenesis Cell aregenerative

AKA/Congenital red

Blackfan anemia

AKA//Chronic

Imperfecta

AKA/Imperfecta

Chronic

blackfan anemia/

Congenital red

anemia/

Erythrogenesis

/Erythrogenesis

anemia

/primary red

erythroblastopenia

erythroblastopenia/

primary red

cell aplasia/

Joseph Diamond

/Joseph Diamond

cell aplasia

Bizarre multinucleated erythroblasts,

Congenital dyserythropoietic anemia

, increased unconjugated bilirubin, and ineffective

Congenital dyserythropoietic anemia

Anaerobic ATP production

EMP

Production of glutathione that detoxifies peroxide

HMS

Reduce ferric to ferrous

MRS (methemoglobin reductase shunt/pathway)

deficiency ? -bite cell

G6PD deficiency

-Hemolysis by fava beans and primaquine

G6PD deficiency

100

G6PD deficiency -Hemolysis by ? and ?

fava beans and primaquine

other names parasitology

other names parasitology

70問 • 2年前

Yves Laure Pimentel · 111問 · 2年前

PARASITOLOGY

PARASITOLOGY

111問 • 2年前

Yves Laure Pimentel · 64問 · 2年前

HTMLBE

HTMLBE

64問 • 2年前

Yves Laure Pimentel · 61問 · 2年前

CC - 1 LAB. SAFETY, BASIC UNITS, AND CONVERSION FACTOR

CC - 1 LAB. SAFETY, BASIC UNITS, AND CONVERSION FACTOR

61問 • 2年前

Yves Laure Pimentel · 69問 · 2年前

HISTOPATHOLOGY

HISTOPATHOLOGY

69問 • 2年前

CC-2 SPECTROPHOTOMETRY

CC-2 SPECTROPHOTOMETRY

Yves Laure Pimentel · 41問 · 2年前

CC-3 ELECTROPHORESIS

CC-3 ELECTROPHORESIS

41問 • 2年前

Yves Laure Pimentel · 87問 · 2年前

AUBF LAB SAFETY

AUBF LAB SAFETY

87問 • 2年前

CSF 1

CSF 1

Yves Laure Pimentel · 82問 · 2年前

CSF 2

CSF 2

82問 • 2年前

SEMEN 1

SEMEN 1

Yves Laure Pimentel · 7問 · 2年前

SEMEN 2

SEMEN 2

7問 • 2年前

SYNOVIAL FLUID 1

SYNOVIAL FLUID 1

Yves Laure Pimentel · 6問 · 2年前

SYNOVIAL FLUID 2

SYNOVIAL FLUID 2

6問 • 2年前

Yves Laure Pimentel · 25問 · 2年前

SEROUS FLUID

SEROUS FLUID

25問 • 2年前

Yves Laure Pimentel · 44問 · 2年前

PLEURAL FLUID

PLEURAL FLUID

44問 • 2年前

Yves Laure Pimentel · 18問 · 2年前

PERICARDIAL FLUID

PERICARDIAL FLUID

18問 • 2年前

Yves Laure Pimentel · 30問 · 2年前

PERITONEAL FLUID/ ASCITIC FLUID

PERITONEAL FLUID/ ASCITIC FLUID

30問 • 2年前

Yves Laure Pimentel · 92問 · 2年前

AMNIOTIC FLUID

AMNIOTIC FLUID

92問 • 2年前

Yves Laure Pimentel · 80問 · 2年前

FECALYSIS

FECALYSIS

80問 • 2年前

Yves Laure Pimentel · 89問 · 2年前

OTHER BODY FLUIDS

OTHER BODY FLUIDS

89問 • 2年前

Yves Laure Pimentel · 86問 · 2年前

MTLBE- SUHO NOTES

MTLBE- SUHO NOTES

86問 • 2年前

Yves Laure Pimentel · 35問 · 2年前

MTLBE..

MTLBE..

35問 • 2年前

Yves Laure Pimentel · 19問 · 1年前

CC- CHROMATOGRAPHY

CC- CHROMATOGRAPHY

19問 • 1年前

Yves Laure Pimentel · 14問 · 1年前

CC-OSMOMETRY

CC-OSMOMETRY

14問 • 1年前

Yves Laure Pimentel · 43問 · 1年前

CC-ELECTROCHEMISTRY TECHNIQUES

CC-ELECTROCHEMISTRY TECHNIQUES

43問 • 1年前

Yves Laure Pimentel · 49問 · 2年前

CC- CARBOHYDRATES

CC- CARBOHYDRATES

49問 • 2年前

Yves Laure Pimentel · 97問 · 2年前

CC- DIABETES MELLITUS

CC- DIABETES MELLITUS

97問 • 2年前

Yves Laure Pimentel · 57問 · 2年前

MAJOR LIPOPROTEINS

MAJOR LIPOPROTEINS

57問 • 2年前

Yves Laure Pimentel · 63問 · 2年前

MINOR LIPOPROTEINS

MINOR LIPOPROTEINS

63問 • 2年前

Yves Laure Pimentel · 37問 · 2年前

PROTEINS

PROTEINS

37問 • 2年前

Yves Laure Pimentel · 91問 · 2年前

PLASMA PROTEINS 1

PLASMA PROTEINS 1

91問 • 2年前

Yves Laure Pimentel · 98問 · 2年前

PLASMA PROTEINS 2 (ALPHA 2 REGION)

PLASMA PROTEINS 2 (ALPHA 2 REGION)

98問 • 2年前

Yves Laure Pimentel · 61問 · 2年前

MISCELLANEOUS PROTEINS

MISCELLANEOUS PROTEINS

61問 • 2年前

Liver Function Test 1

Liver Function Test 1

Yves Laure Pimentel · 96問 · 2年前

Liver Function Test 2

Liver Function Test 2

96問 • 2年前

Yves Laure Pimentel · 33問 · 2年前

TUMOR MARKERS

TUMOR MARKERS

33問 • 2年前

Yves Laure Pimentel · 41問 · 2年前

KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

KIDNEY FUNCTION TESTS - NON PROTEIN NITROGEN & CREATININE

41問 • 2年前

Yves Laure Pimentel · 17問 · 2年前

GLYCOGEN STORAGE DISEASES

GLYCOGEN STORAGE DISEASES

17問 • 2年前

Yves Laure Pimentel · 14問 · 2年前

LIPID STORAGE DISEASES

LIPID STORAGE DISEASES

14問 • 2年前

Yves Laure Pimentel · 71問 · 2年前

PROTEINS

PROTEINS

71問 • 2年前

Yves Laure Pimentel · 7問 · 2年前

QUICK FIRE- ELECTRODES

QUICK FIRE- ELECTRODES

7問 • 2年前

Yves Laure Pimentel · 10問 · 2年前

ELECTROLYTES

ELECTROLYTES

10問 • 2年前

Yves Laure Pimentel · 27問 · 2年前

DRUGS

DRUGS

27問 • 2年前

Yves Laure Pimentel · 12問 · 2年前

TOXIC AGENTS:

TOXIC AGENTS:

12問 • 2年前

HEMATOLOGY 1 (HEMATOPOIESIS 1)

HEMATOLOGY 1 (HEMATOPOIESIS 1)

Yves Laure Pimentel · 29問 · 2年前

HEMATOLOGY (HEMATOPOIESIS 2)

HEMATOLOGY (HEMATOPOIESIS 2)

29問 • 2年前

Yves Laure Pimentel · 25問 · 2年前

hema diseases

hema diseases

25問 • 2年前

Yves Laure Pimentel · 43問 · 2年前

AML

AML

43問 • 2年前

Yves Laure Pimentel · 71問 · 2年前

GLOBIN SYNTHESIS

GLOBIN SYNTHESIS

71問 • 2年前

Yves Laure Pimentel · 31問 · 2年前

HEMATOLOGY REFERENCE RANGES

HEMATOLOGY REFERENCE RANGES

31問 • 2年前

Yves Laure Pimentel · 34問 · 2年前

DISORDERS OF PRIMARY HEMOSTASIS

DISORDERS OF PRIMARY HEMOSTASIS

34問 • 2年前

Yves Laure Pimentel · 37問 · 2年前

PLATELET DISORDERS

PLATELET DISORDERS

37問 • 2年前

CHARACTERISTICS OF CLOTTING FACTORS

CHARACTERISTICS OF CLOTTING FACTORS

Yves Laure Pimentel · 12問 · 2年前

4. CLASSIFICATION OF MACROPHAGE

4. CLASSIFICATION OF MACROPHAGE

12問 • 2年前

Yves Laure Pimentel · 39問 · 2年前

3. NATURAL OR INNATE IMMUNITY

3. NATURAL OR INNATE IMMUNITY

39問 • 2年前

Yves Laure Pimentel · 55問 · 2年前

5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

5. INTERNAL DEFENSE:SOLUBLE FACTORS (ACUTE PHASE REACTANTS)

55問 • 2年前

Yves Laure Pimentel · 37問 · 2年前

6. PHAGOCYTOSIS Chemotaxis

6. PHAGOCYTOSIS Chemotaxis

37問 • 2年前

Yves Laure Pimentel · 44問 · 2年前

8. NATURE OF ANTIGEN

8. NATURE OF ANTIGEN

44問 • 2年前

Yves Laure Pimentel · 50問 · 2年前

9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

9. MAJOR HISTOCOMPATIBILITY COMPLEX/HUMAN LEUKOCYTE ANTIGEN

50問 • 2年前

Yves Laure Pimentel · 69問 · 2年前

1. HISTORY

1. HISTORY

69問 • 2年前

Yves Laure Pimentel · 38問 · 2年前

2. TYPES OF IMMUNITY

2. TYPES OF IMMUNITY

38問 • 2年前

Yves Laure Pimentel · 21問 · 2年前

7. PHAGOCYTOSIS Engulfment and Digestion

7. PHAGOCYTOSIS Engulfment and Digestion

21問 • 2年前

Yves Laure Pimentel · 15問 · 2年前

8. PHAGOCYTOSIS EXOCYTOSIS

8. PHAGOCYTOSIS EXOCYTOSIS

15問 • 2年前

Yves Laure Pimentel · 32問 · 2年前

10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

10. DISEASE ASSOCIATED TO HUMAN LEUKOCYTE ANTIGEN (henry)

32問 • 2年前

Yves Laure Pimentel · 30問 · 2年前

11. TRANSPLANTATION IMMUNOLOGY

11. TRANSPLANTATION IMMUNOLOGY

30問 • 2年前

Yves Laure Pimentel · 38問 · 2年前

2. LYMPHOID ORGANS

2. LYMPHOID ORGANS

38問 • 2年前

Yves Laure Pimentel · 48問 · 2年前

3. CLUSTER OF DIFFERENTIATION

3. CLUSTER OF DIFFERENTIATION

48問 • 2年前

Yves Laure Pimentel · 35問 · 2年前

4. T-CELL DIFFERENTIATION

4. T-CELL DIFFERENTIATION

35問 • 2年前

Yves Laure Pimentel · 18問 · 2年前

5. T CELL IMMUNODEFICIENCIES

5. T CELL IMMUNODEFICIENCIES

18問 • 2年前

Yves Laure Pimentel · 44問 · 2年前

6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

6. STAGES IN B-CELL DIFFERENTIATION  PROPIMAP

44問 • 2年前

Yves Laure Pimentel · 23問 · 2年前

7. B CELL IMMUNODEFICIENCIES

7. B CELL IMMUNODEFICIENCIES

23問 • 2年前

Yves Laure Pimentel · 34問 · 2年前

8. COMBINED T CELL AND B CELL DEFICIENCIES

8. COMBINED T CELL AND B CELL DEFICIENCIES

34問 • 2年前

Yves Laure Pimentel · 12問 · 2年前

9. COMPARISON OF T AND B CELLS

9. COMPARISON OF T AND B CELLS

12問 • 2年前

Yves Laure Pimentel · 16問 · 2年前

10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

10. LABORATORY IDENTIFICATION OF LYMPHOCYTES

16問 • 2年前

Yves Laure Pimentel · 15問 · 2年前

11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

11. NATURAL KILLER CELLS OR THIRD POPULATION CELL

15問 • 2年前

Yves Laure Pimentel · 79問 · 2年前

12. ANTIBODY

12. ANTIBODY

79問 • 2年前

Yves Laure Pimentel · 97問 · 2年前

13. TYPES OF ANTIBODIES

13. TYPES OF ANTIBODIES

97問 • 2年前

Yves Laure Pimentel · 11問 · 2年前

14. MONOCLONAL ANTIBODIES

14. MONOCLONAL ANTIBODIES

11問 • 2年前

Yves Laure Pimentel · 23問 · 2年前

1. INTERLEUKINS

1. INTERLEUKINS

23問 • 2年前

Yves Laure Pimentel · 28問 · 2年前

2. INTERFERONS

2. INTERFERONS

28問 • 2年前

Yves Laure Pimentel · 8問 · 2年前

3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

3. CYTOKINES IN THE INNATE AND ADAPTIVE IMMUNITY

8問 • 2年前

Yves Laure Pimentel · 19問 · 2年前

4. COMPLEMENT SYSTEM

4. COMPLEMENT SYSTEM

19問 • 2年前

Yves Laure Pimentel · 76問 · 2年前

15. COMPLEMENT SYSTEM

15. COMPLEMENT SYSTEM

76問 • 2年前

Yves Laure Pimentel · 21問 · 2年前

16. SYSTEM CONTROLS/COMPLEMENT REGULATION

16. SYSTEM CONTROLS/COMPLEMENT REGULATION

21問 • 2年前

Yves Laure Pimentel · 29問 · 2年前

17. COMPLEMENT AND DISEASE STATES

17. COMPLEMENT AND DISEASE STATES

29問 • 2年前

Yves Laure Pimentel · 19問 · 2年前

18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

18. IMMUNOLOGIC ASSAYS OF INDIVIDUAL COMPONENTS (CLASSICAL)

19問 • 2年前

Yves Laure Pimentel · 22問 · 2年前

19. CYTOKINES

19. CYTOKINES

22問 • 2年前

Yves Laure Pimentel · 24問 · 2年前

20. INTERLEUKINS

20. INTERLEUKINS

24問 • 2年前

Yves Laure Pimentel · 21問 · 2年前

21. INTERFERONS, TNF, TGF, CHEMOKINE

21. INTERFERONS, TNF, TGF, CHEMOKINE

21問 • 2年前

Yves Laure Pimentel · 54問 · 2年前

1. SERO

1. SERO

54問 • 2年前

Yves Laure Pimentel · 38問 · 2年前

2. PRECIPITATION

2. PRECIPITATION

38問 • 2年前

Yves Laure Pimentel · 17問 · 2年前

3. PASSIVE IMMUNODIFFUSION

3. PASSIVE IMMUNODIFFUSION

17問 • 2年前

Yves Laure Pimentel · 15問 · 2年前

4. OUCHTERLONY

4. OUCHTERLONY

15問 • 2年前

Yves Laure Pimentel · 9問 · 2年前

5. ELECTROPHORETIC TECHNIQUE

5. ELECTROPHORETIC TECHNIQUE

9問 • 2年前

Yves Laure Pimentel · 11問 · 2年前

6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

6. IMMUNOELECTROPHORESIS (DOUBLE DIFFUSION)

11問 • 2年前

Yves Laure Pimentel · 29問 · 2年前

7. IMMUNOFIXATION ELECTROPHORESIS

7. IMMUNOFIXATION ELECTROPHORESIS

29問 • 2年前