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RBC STRUCTURE AND FUNCTION

RBC STRUCTURE AND FUNCTION
55問 • 1年前
  • Jamaica Jade Labadan
    • 通報

    問題一覧

  • 1

    Hemoglobin is made up of ???? amino acids?

    574

  • 2

    1 gram of HgB = ???

    1.34 mL oxygen

  • 3

    the manner in which bindingto reduce hemoglobin(affects oxygen affinity quite complex)

    Deoxyhemoglobin

  • 4

    Oxygenated hemoglobin

    Oxyhemoglobin

  • 5

    disease in oxygen levels

    Hypoxia

  • 6

    DELTA POR UR COP PROTO HEME

    DELTA- aminolevulinic acid PORphobilinogen URoporphyrinogen COProporphyrinogen PROTOporphyrin HEME+ Globin 4 hemoglobin

  • 7

    Most abundant transitional metal in the body.

    Iron

  • 8

    water-soluble complex of ferric salt and a protein, apoferri stored in bone marrow

    Ferritin

  • 9

    Water insoluble and consists mostly of aggregates of ferric oxyhydroxide core crystals w/ partially or completely degraded protein shell Usually found in various tissue

    Hemosiderin

  • 10

    Protein that transfers iron to normoblasts

    Transferrin

  • 11

    Transforming iron to the ferric form to enable its upstake by circulating apotransferrin

    Hephaestin

  • 12

    Also has ferroxidase activity and is involved as well in the release of iron from the cells.

    Ceruloplasmin

  • 13

    Master regulatory hormone of systemic iron metabolism

    Hepcidin

  • 14

    Plasma protein that binds heme

    hemopexin

  • 15

    binds hemoglobin; prevents urinary excretion of plasma hemoglobin

    haptoglobin

  • 16

    ALPHA CHAINS

    141 amino acids

  • 17

    Beta chains

    146 amino acids

  • 18

    Primitive hemoglobin Are formed by immature erythrocytes in the yolk sac.

    Embryonic hemoglobin

  • 19

    Major Hb in fetus and in newborn infant.

    Hemoglobin F

  • 20

    Major normal adult Hb

    Hemoglobin A

  • 21

    A stable hemoglobin

    Glycosylated hemoglobin

  • 22

    Major source of the essential cellular energy

    Embden-Meyerhof pathway

  • 23

    Also known as hexose mono phosphate shunt.

    Pentose Phosphate Pathway

  • 24

    Maintains hemoglobin iron in ferrous state.

    Methemoglobin Reduction

  • 25

    Premature infants erythrocytes lifespan: ?

    35-50 days

  • 26

    Fetuses erythrocytes lifespan: ???

    60 to 70 days

  • 27

    Happens out of the blood vessels and in the reticular endothelial cells.

    Extravascular catabolism

  • 28

    Major hemolytic anemia Happens within the blood vessels

    Intravascular Catabolism

  • 29

    Refers to the total production of hemoglobin or red cells

    Total erythropoiesis

  • 30

    Refers to the production of hemoglobin or rbc that reach the circulation

    Effective erythropoiesis

  • 31

    Refers to production of hemoglobin or rbc that never reach circulation

    ineffective erythropoiesis

  • 32

    Diameter less than 6; 5 um seen in iron deficiency anemias

    Microcytes

  • 33

    Increased variability im rbc size. Seen in megaloblastic. anemias

    Anisocytosis

  • 34

    Diameter greater than 8.5 um seen in megaloblastic anemias and B12 deficiency

    Macrocytes

  • 35

    Result of a defect in either nuclear maturation or stimulated erythropoiesis

    Macrosytosis

  • 36

    Associated with a decrease in hemoglobin synthesis

    Microsytosis

  • 37

    Other name: Thorn cells, spur cells multiple thorny, spike like projections that are irregularly distributed around the cellular membrane and may vary in size.

    ACANTHOCYTES

  • 38

    Other name: Bronze cells Round shape; extremely dense or compact; lack central pallor

    Spherocytes

  • 39

    Other name: Bulls eye; target cells; Mexican Hat A peripheral rim of Hb w/ dark central, Hb- cointaining area.

    Codocytes

  • 40

    Have a slit like opening that resembles a mouth

    Stomatocytes

  • 41

    Rod, cigar, or sausage shape

    Elliptocytes

  • 42

    Pocket-book cell Erythrocytes containing one or more vacuoles that resemble a blister on the skin

    Bloster cells

  • 43

    Distorted contracted erythrocytes

    Pyknocytes

  • 44

    Helmet cell; blister cell; horned cell Appears like a half moon or spindle

    Keratocytes

  • 45

    Bite cell Appearance of the rbc is altered w hemoglobin being confined to one side of the cell, although the other side of the cell is transparent

    Degmacytes

  • 46

    Schizocytes Fragments of erythrocytes that are small and irregularly shape

    Schistocytes

  • 47

    resembles a pinched bottle, triconcave Rbc w a “ridge”

    Knizocytes

  • 48

    Burr cells; crenated erythrocytes short, scallod or spike like projection that are regularly distributed around cell membrane

    Echinocytes

  • 49

    Teardrop cell Used smaller than normal erythrocytes

    Dacrocytes

  • 50

    Sickle cell Resembles a crescent shape and has a pointed projections at one of the terminal ends of rbc

    Depranocytes

  • 51

    Resembling crenated cells consisting of tiny pits of bubbles indenting the red cells maybe cause by a small amount of water contaminatinh Wright stain

    Artifacts

  • 52

    “Washington monument”

    Hemoglobin SC

  • 53

    Stains dark red and resembles clam shells

    Hemoglobin C

  • 54

    Arrangement of erythroicytes in groups that resembles stacks of coin, is usually present in the thick portions of normal blood smears

    Roulex Formation

  • 55

    Presence of normoblast & immature cells of the neutrophilic series in the blood

    Leucoerythroblastic reaction

    • BLOOD COLLECTION

    BLOOD COLLECTION

    Jamaica Jade Labadan · 20問 · 2年前

    BLOOD COLLECTION

    BLOOD COLLECTION

    20問 • 2年前
    Jamaica Jade Labadan

    HEMATOPOIESIS

    HEMATOPOIESIS

    Jamaica Jade Labadan · 37問 · 1年前

    HEMATOPOIESIS

    HEMATOPOIESIS

    37問 • 1年前
    Jamaica Jade Labadan

    問題一覧

  • 1

    Hemoglobin is made up of ???? amino acids?

    574

  • 2

    1 gram of HgB = ???

    1.34 mL oxygen

  • 3

    the manner in which bindingto reduce hemoglobin(affects oxygen affinity quite complex)

    Deoxyhemoglobin

  • 4

    Oxygenated hemoglobin

    Oxyhemoglobin

  • 5

    disease in oxygen levels

    Hypoxia

  • 6

    DELTA POR UR COP PROTO HEME

    DELTA- aminolevulinic acid PORphobilinogen URoporphyrinogen COProporphyrinogen PROTOporphyrin HEME+ Globin 4 hemoglobin

  • 7

    Most abundant transitional metal in the body.

    Iron

  • 8

    water-soluble complex of ferric salt and a protein, apoferri stored in bone marrow

    Ferritin

  • 9

    Water insoluble and consists mostly of aggregates of ferric oxyhydroxide core crystals w/ partially or completely degraded protein shell Usually found in various tissue

    Hemosiderin

  • 10

    Protein that transfers iron to normoblasts

    Transferrin

  • 11

    Transforming iron to the ferric form to enable its upstake by circulating apotransferrin

    Hephaestin

  • 12

    Also has ferroxidase activity and is involved as well in the release of iron from the cells.

    Ceruloplasmin

  • 13

    Master regulatory hormone of systemic iron metabolism

    Hepcidin

  • 14

    Plasma protein that binds heme

    hemopexin

  • 15

    binds hemoglobin; prevents urinary excretion of plasma hemoglobin

    haptoglobin

  • 16

    ALPHA CHAINS

    141 amino acids

  • 17

    Beta chains

    146 amino acids

  • 18

    Primitive hemoglobin Are formed by immature erythrocytes in the yolk sac.

    Embryonic hemoglobin

  • 19

    Major Hb in fetus and in newborn infant.

    Hemoglobin F

  • 20

    Major normal adult Hb

    Hemoglobin A

  • 21

    A stable hemoglobin

    Glycosylated hemoglobin

  • 22

    Major source of the essential cellular energy

    Embden-Meyerhof pathway

  • 23

    Also known as hexose mono phosphate shunt.

    Pentose Phosphate Pathway

  • 24

    Maintains hemoglobin iron in ferrous state.

    Methemoglobin Reduction

  • 25

    Premature infants erythrocytes lifespan: ?

    35-50 days

  • 26

    Fetuses erythrocytes lifespan: ???

    60 to 70 days

  • 27

    Happens out of the blood vessels and in the reticular endothelial cells.

    Extravascular catabolism

  • 28

    Major hemolytic anemia Happens within the blood vessels

    Intravascular Catabolism

  • 29

    Refers to the total production of hemoglobin or red cells

    Total erythropoiesis

  • 30

    Refers to the production of hemoglobin or rbc that reach the circulation

    Effective erythropoiesis

  • 31

    Refers to production of hemoglobin or rbc that never reach circulation

    ineffective erythropoiesis

  • 32

    Diameter less than 6; 5 um seen in iron deficiency anemias

    Microcytes

  • 33

    Increased variability im rbc size. Seen in megaloblastic. anemias

    Anisocytosis

  • 34

    Diameter greater than 8.5 um seen in megaloblastic anemias and B12 deficiency

    Macrocytes

  • 35

    Result of a defect in either nuclear maturation or stimulated erythropoiesis

    Macrosytosis

  • 36

    Associated with a decrease in hemoglobin synthesis

    Microsytosis

  • 37

    Other name: Thorn cells, spur cells multiple thorny, spike like projections that are irregularly distributed around the cellular membrane and may vary in size.

    ACANTHOCYTES

  • 38

    Other name: Bronze cells Round shape; extremely dense or compact; lack central pallor

    Spherocytes

  • 39

    Other name: Bulls eye; target cells; Mexican Hat A peripheral rim of Hb w/ dark central, Hb- cointaining area.

    Codocytes

  • 40

    Have a slit like opening that resembles a mouth

    Stomatocytes

  • 41

    Rod, cigar, or sausage shape

    Elliptocytes

  • 42

    Pocket-book cell Erythrocytes containing one or more vacuoles that resemble a blister on the skin

    Bloster cells

  • 43

    Distorted contracted erythrocytes

    Pyknocytes

  • 44

    Helmet cell; blister cell; horned cell Appears like a half moon or spindle

    Keratocytes

  • 45

    Bite cell Appearance of the rbc is altered w hemoglobin being confined to one side of the cell, although the other side of the cell is transparent

    Degmacytes

  • 46

    Schizocytes Fragments of erythrocytes that are small and irregularly shape

    Schistocytes

  • 47

    resembles a pinched bottle, triconcave Rbc w a “ridge”

    Knizocytes

  • 48

    Burr cells; crenated erythrocytes short, scallod or spike like projection that are regularly distributed around cell membrane

    Echinocytes

  • 49

    Teardrop cell Used smaller than normal erythrocytes

    Dacrocytes

  • 50

    Sickle cell Resembles a crescent shape and has a pointed projections at one of the terminal ends of rbc

    Depranocytes

  • 51

    Resembling crenated cells consisting of tiny pits of bubbles indenting the red cells maybe cause by a small amount of water contaminatinh Wright stain

    Artifacts

  • 52

    “Washington monument”

    Hemoglobin SC

  • 53

    Stains dark red and resembles clam shells

    Hemoglobin C

  • 54

    Arrangement of erythroicytes in groups that resembles stacks of coin, is usually present in the thick portions of normal blood smears

    Roulex Formation

  • 55

    Presence of normoblast & immature cells of the neutrophilic series in the blood

    Leucoerythroblastic reaction