Other name: Bronze cells Round shape; extremely dense or compact; lack central pallor

Oxygenated hemoglobin

Teardrop cell Used smaller than normal erythrocytes

Schizocytes Fragments of erythrocytes that are small and irregularly shape

Bite cell Appearance of the rbc is altered w hemoglobin being confined to one side of the cell, although the other side of the cell is transparent

DELTA POR UR COP PROTO HEME

Associated with a decrease in hemoglobin synthesis

Sickle cell Resembles a crescent shape and has a pointed projections at one of the terminal ends of rbc

Transforming iron to the ferric form to enable its upstake by circulating apotransferrin

A stable hemoglobin

Helmet cell; blister cell; horned cell Appears like a half moon or spindle

Refers to the production of hemoglobin or rbc that reach the circulation

Fetuses erythrocytes lifespan: ???

Stains dark red and resembles clam shells

Most abundant transitional metal in the body.

Major normal adult Hb

Protein that transfers iron to normoblasts

1 gram of HgB = ???

Happens out of the blood vessels and in the reticular endothelial cells.

Beta chains

Also known as hexose mono phosphate shunt.

“Washington monument”

Major source of the essential cellular energy

water-soluble complex of ferric salt and a protein, apoferri stored in bone marrow

Rod, cigar, or sausage shape

the manner in which bindingto reduce hemoglobin(affects oxygen affinity quite complex)

Major hemolytic anemia Happens within the blood vessels

resembles a pinched bottle, triconcave Rbc w a “ridge”

Increased variability im rbc size. Seen in megaloblastic. anemias

Pocket-book cell Erythrocytes containing one or more vacuoles that resemble a blister on the skin

Water insoluble and consists mostly of aggregates of ferric oxyhydroxide core crystals w/ partially or completely degraded protein shell Usually found in various tissue

Diameter greater than 8.5 um seen in megaloblastic anemias and B12 deficiency

Master regulatory hormone of systemic iron metabolism

ALPHA CHAINS

Primitive hemoglobin Are formed by immature erythrocytes in the yolk sac.

Presence of normoblast & immature cells of the neutrophilic series in the blood

Refers to the total production of hemoglobin or red cells

Major Hb in fetus and in newborn infant.

binds hemoglobin; prevents urinary excretion of plasma hemoglobin

Other name: Bulls eye; target cells; Mexican Hat A peripheral rim of Hb w/ dark central, Hb- cointaining area.

disease in oxygen levels

Refers to production of hemoglobin or rbc that never reach circulation

Maintains hemoglobin iron in ferrous state.

Premature infants erythrocytes lifespan: ?

Plasma protein that binds heme

Hemoglobin is made up of ???? amino acids?

Diameter less than 6; 5 um seen in iron deficiency anemias

Resembling crenated cells consisting of tiny pits of bubbles indenting the red cells maybe cause by a small amount of water contaminatinh Wright stain

Distorted contracted erythrocytes

Also has ferroxidase activity and is involved as well in the release of iron from the cells.

Other name: Thorn cells, spur cells multiple thorny, spike like projections that are irregularly distributed around the cellular membrane and may vary in size.

Arrangement of erythroicytes in groups that resembles stacks of coin, is usually present in the thick portions of normal blood smears

Burr cells; crenated erythrocytes short, scallod or spike like projection that are regularly distributed around cell membrane

Have a slit like opening that resembles a mouth

Result of a defect in either nuclear maturation or stimulated erythropoiesis