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  • 問題数 105 • 6/27/2024

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    問題一覧

  • 1

    Select that is characteristic for agony stage of terminal state:

    Qasping respiration

  • 2

    Characterize the biological death.

    formation of irreversible changes in the cerebral cortex

  • 3

    Select the cause of infectious complication during acute radiation disease:

    leukopenia

  • 4

    Select that is not characteristic for crash syndrome:

    hemodilution

  • 5

    Select that is not characteristic for desaturation:

    increasing dissolving of gaseous in the blood

  • 6

    Select that is not characteristic for complete stage of acute radiation disease:

    decreasing of residual nitrogen in the blood

  • 7

    Which change is observed on cells under direct influence of ionizing radiation?

    fragmentation of DNA molecules

  • 8

    Select the defensive-compensatory mechanism that prevents ionizing radiation:

    activation of DNA reparation system

  • 9

    Select the sequence of pancytopenia during acute radiation disease:

    lymphocytopenia, neutropenia, thrombocytopenia, anemia

  • 10

    Choose the cause of hemorrhagic syndrome during acute radiation sickness?

    thrombocytopenia

  • 11

    Select that is not characteristic for agammaglobulinemia:

    inherits by autosomal dominant way

  • 12

    Select that is not characteristic for daltonism:

    inherits by autosomal recessive way

  • 13

    Select that is not characteristic for expansion of triplet nucleotides:

    inherits by X-chromosomal recessive way

  • 14

    The following changes are appeared in blood after a day of radiation (3. 5 Qr): erythrocytes - 4. 7·1012/l, hemoglobin – 120 g/l, leukocytes - 11·109 /l, thrombocytes - 270·109 /l. Blood smear: basophiles-1%, eosinophiles-3%, neutrophiles-81%, lymphocytes- 11%, monocytes-4%. For which period of acute radiation sickness all these changes are characteristic?

    period of initial manifestations

  • 15

    Select that is characteristic for Recklinghausen disease:

    neurogenic tumors that develops along of nervous fibers

  • 16

    Select that is characteristic for burn disease:

    increasing of ESR

  • 17

    Select the main reason of hemolysis during burn disease:

    entering of toxic substances into the blood from injured tissues

  • 18

    Select that is characteristic for erectile stage of burn shock:

    increasing activity of circulatory system

  • 19

    Select the changes of nervous system during torpid stage of burn shock.

    inhibition activity of brain cortex and subcortical nucleus

  • 20

    Select that is not characteristic for exhaustion stage of burn disease:

    hypertrophy of adrenal cortex

  • 21

    Select that is not the cause of hypercalciemia:

    decreasing reabsorption of calcium in renal tubules

  • 22

    Select irreversible change during cell injury:

    damage of lyzosomal membrane

  • 23

    Select the incorrect version:

    at first lymphocytes emigrate to the focus of inflammation

  • 24

    Choose the condition of saturation of gases:

    high atmospheric pressure

  • 25

    Select the chemotaxins: 1) Bacterial lypoipolysacharides 2) C-reactive protein 3) IL-8 4) IgG 5) PAF

    1, 3, 5

  • 26

    Oxyhemoglobin dissociation curve shift to the left is observed during: 1) Hypocapnia 2) Increasing of 2,3 diphosphoglycerate in erythrocytes 3) Thalassemia 4) Decreasing of body temperature 5) Hypercapnia

    1,3,4

  • 27

    Oxyhemoglobin dissociation curve shift to the right is observed during: 1) Thalassemia 2) Hypercapnia 3) Increasing of 2,3 diphosphoglycerate in erythrocytes 4) Chronic hypoxia 5) Increasing of body temperature

    2,3,5

  • 28

    Similar feature of tissue hypoxia and hemic hypoxia:

    development of non-gaseous acidosis

  • 29

    Respirator hypoxia is accompanied with: 1) Hypercapnia 2) Spasm of cerebral vessels 3) Gaseous acidosis 4) Hypocalcemia 5) Oxyhemoglobin dissociation curve shift to the right

    1,3,5

  • 30

    Hemic hypoxia develops during:

    poisoning with bertole salt

  • 31

    Choose the type of hypoxia accompanied with increasing of PvO2:

    tissue

  • 32

    Chronic hypoxia develops during: 1) Heart defects 2) Poisoning with cyanides 3) Iron deficiency anemia 4) Asphyxia 5) Cardiac asthma

    1,3

  • 33

    Choose that is accompanied by local endogenous hypoxia: 1) Ischemia 2) Venous hyperemia 3) Mountain disease 4) High altitude disease 5) Stasis

    1,2,5

  • 34

    Choose that is the reason of development of circulatory hypoxia of vascular origin:

    insufficiency of adrenal glands

  • 35

    Choose that is the reason of development of system circulatory hypoxia: 1) Venous hyperemia 2) Hypovolemy 3) Cardiac insufficiency 4) Stasis 5) Decreasing of vascular tonicity

    2,3,5

  • 36

    Choose that is the reason of development of centralization of blood circulation during hypoxia:

    activation of symphato-adrenal system

  • 37

    Determine the changes in electrolyte metabolism during extreme states: 1) Increasing of intracellular Na+ 2) Increasing of extracellular K+ 3) Increasing of intracellular Mg2+ 4) Increasing of extracellular Na+ 5) Increasing of intracellular Ca2+

    1,2,5

  • 38

    Difference of torpid phase of shock from erectile:

    hyporeflexia is observed

  • 39

    Characteristic feature of burn shock:

    massive loss of plasma

  • 40

    Choose that is the reason of development of vasodilatory collapse:

    decreasing of peripheral vascular resistance

  • 41

    Match the followings: The reasons of coma: I. Exogenous II. Endogenous a) neurotropic viruses b) ischemic insult c) starvation d) hypoinsulinism e) insufficiency of adrenal gland I II

    a, c b, d, e

  • 42

    Match the followings: I. Shock II. Collapse 1) Primary changes occur in nervous system 2) Vasodilator and hypovolemic types are distinguished 3) Primary changes occur in cardio-vascular system 4) Erectile and torpid phases are distinguished I II

    1,4 2,3

  • 43

    Choose the incorrect version:

    in erectile stage of shock hypocatecholaminemia develops

  • 44

    In this type of extreme states the primary changes occur in nervous system:

    traumatic shock

  • 45

    Choose that is not characteristic for coma:

    hyperreflexia

  • 46

    Leads to development of "shock kidneys": 1) Hypervolemy 2) Postcapillary angiospasm 3) Hyperfiltration in glomeruli 4) Hypoperfusion of kidneys 5) Hyperoxemia

    2,4

  • 47

    Choose the pathogenetic factor of collapse:

    decreasing of peripheral vascular resistance

  • 48

    Choose that is not belong to the pathogenetic therapy of comatose states:

    using of antidotes

  • 49

    Orthostatic collapse develops during:

    sudden passage from bed regime to the vertical position

  • 50

    The type of collapse developing during insufficiency of adrenal gland:

    vasodilatation

  • 51

    Determine the sequence of mechanisms during "shock kidneys": 1) Acute renal insufficiency 2) Decreasing of filtration pressure in renal glomeruli 3) Extreme irritant 4) Disturbances of filtration and reabsorption 5) Disturbance of blood circulation

    3,5,2,4,1

  • 52

    Choose that is not belong to the microcirculatory changes during collapse:

    hypervolemy

  • 53

    Choose the correct version:

    collapse is accompanied by decreasing of venous pressure

  • 54

    Formation and differentiation of T-lymphocytes is disturbed: 1) Di-George syndrome 2) West syndrome 3) Bruton syndrome 4) Mac-Kusic syndrome 5) Neselof syndrome

    1,4,5

  • 55

    Choose the immune deficiency syndrome which accompanied with exema and thrombocytopenia:

    Wiskott-Aldrige syndrome

  • 56

    Choose the target cells of AIDS virus :

    CD4+ lymphocytes

  • 57

    Choose the immune deficiency syndrome which accompanied with ataxia and teleangiectasia:

    Louis-Bar syndrome

  • 58

    Choose the immune deficiency syndrome which accompanied with cleft palate and coarctation of aorta:

    Di-George syndrome

  • 59

    Choose the reason why B-lymphocytes can’t recognize antigens in AIDS:

    due to damaging of CD4 + Th2 cells

  • 60

    Choose the immunological marker of autoimmune hemolytic anemia:

    autoantibodies against Rh-antigen

  • 61

    Choose the immunological marker of myasthenia gravis:

    antibodies against acetylcholine receptors

  • 62

    Choose that is not autoimmune disease:

    Glanzmann-Riniker syndrome

  • 63

    Select the peripheral mechanisms of physiological tolerance: 1) Anergia 2) Immune deficiency states 3) Supression by regulatory T- cells 4) Excess activatipon of T-supressors 5) Apoptosis 6) Excess load of immune system by antigens

    1,3,5

  • 64

    Select the mechanisms of development of auto-allergic diseases: 1) Disturbance of activation of complement sysytem 2) Hereditary predisposition 3) Infection 4) Disturbance metabolism of arachidonic acid 5) Disturbance of immunological tolerance 6) Non-adequate degranulation of must cells

    2,3,5

  • 65

    Select the genes that controls passage of G1 phase to the S phase in cellular cycle: 1) Rb 2) p53 3) ERB-1 4) N-RAS 5) K-RAS 6) TGF-β

    1,2,6

  • 66

    Hypoosmolar hyperhydration is observed during:

    increasing secretion of antidiuretuc hormone

  • 67

    Pathological hypoglycemia is not observed during:

    pheochromacytoma

  • 68

    Select the main sign of hypercalciemia:

    nephrolithiasis

  • 69

    Select the main sign of hypernatriemia:

    arterial hypertension

  • 70

    Select that is characteristic for Costmann disease:

    disturbance prolipheration of granulocytar stem cells in bone marrow

  • 71

    Select that is characteristic for “lazy” leukocyte syndrome:

    disturbance polimeration of actin microfilament in phagocytes

  • 72

    Prolypherative inflammation is not observed during:

    absesses

  • 73

    Select that is not observed during emboli of portal vein:

    increasing of circulated blood volume

  • 74

    Damage of cell by protein mechanism leads to:

    activation of chaperons

  • 75

    Choose the characteristic features of the typical pathological processes ?

    pathological processes is a poly- etiological, mono- pathogenetical and has general regularities of development

  • 76

    Choose the correct sequence of destroying of organs and tissues in the process of death.

    cerebral cortex, subcortical nuclei, brain stem, spinal cord, parenchymatous organs

  • 77

    What does the semiotic mean?

    teaching about signs and mechanisms of development of diseases

  • 78

    What does the etiology mean?

    teaching about reasons and conditions of diseases

  • 79

    What does the pathogenesis mean?

    teaching about mechanisms of development, course and outcomes of diseases

  • 80

    What does the pathological process mean?

    unity of damaging and compensation reactions of the organism after influence of pathogenic factors

  • 81

    What does the vicious circle mean?

    Causative-result interrelations replay each other in a such way, that after some sequence of processes the pathogenical mechanisms are aggravated

  • 82

    What does the pathological reaction mean?

    extraordinary reactions with short duration to stimulation

  • 83

    The main link of pathogenesis:

    dilation arterioles in arterial hyperemia

  • 84

    Choose the outcomes of the disease:

    recovery, relapse, death, transition to the chronic form

  • 85

    Select the correct sequences of the stages of disease:

    latent, prodromal, the period of clinical manifestations, outcome

  • 86

    Select the main change of pathological process which leads to the development of all other stages:

    main link of pathogenesis

  • 87

    Protracted disturbance of functions and structures of the organs is called:

    pathological state

  • 88

    Characterize the latent period of diseases.

    the period occurred before appearance of the first symptoms of disease

  • 89

    Select the local change of disease:

    increasing the volume of organ and tissues

  • 90

    Select the typical pathological processes: 1) Diabetes mellitus 2) Gastritis 3) Cell injury 4) Fever

    3, 4

  • 91

    Select the pathological states: 1) Scar 2) Gastritis 3) Gastric ulcer 4) Birthmark

    1, 4

  • 92

    Match the versions: Ways of spreading of pathogenic agents Diseases Hematogenic Х Lymphogenic Y Through the nervous fibers Z

    X-sarcoma, Y-cancer disease, Z-tetanus viruses

  • 93

    Choose the pathological states. 1) Inflammation 2) The state after amputation 3) Fever 4) Scar after burn 5) Birthmark

    2, 4, 5

  • 94

    Choose the diseases. 1) Lung cancer 2) Edema 3) Appendicitis 4) Hypoxia 5) Tonsillitis

    1, 3, 5

  • 95

    Choose the outcome of disease. 1) Stomach ulcer 2) Relapse 3) Agony 4) Terminal pause 5) Death

    2, 5

  • 96

    Choose the immediate mechanisms of sanogenesis. 1) Vomiting 2) Acceleration of erythropoiesis 3) Development of collaterals 4) Sneezing 5) Production of antibody

    1, 4

  • 97

    Choose the factor which influences only in the beginning of disease:

    ionizing radiation

  • 98

    Select the base of pathogenetic therapy of allergic disease:

    inhibition synthesis of antibodies

  • 99

    Choose the relative stable defensive – adaptation reaction:

    reaction elements of connective tissue

  • 100

    Choose the stable defensive – adaptation reaction:

    regeneration