問題一覧
1
Hemic hypoxia develops during:
poisoning with bertole salt
2
Choose the correct version:
collapse is accompanied by decreasing of venous pressure
3
Pathological hypoglycemia is not observed during:
pheochromacytoma
4
Select that is characteristic for burn disease:
increasing of ESR
5
Choose the correct sequence of destroying of organs and tissues in the process of death.
cerebral cortex, subcortical nuclei, brain stem, spinal cord, parenchymatous organs
6
Choose that is the reason of development of circulatory hypoxia of vascular origin:
insufficiency of adrenal glands
7
Choose the relative stable defensive – adaptation reaction:
reaction elements of connective tissue
8
Choose that is the reason of development of vasodilatory collapse:
decreasing of peripheral vascular resistance
9
Choose the pathogenetic factor of collapse:
decreasing of peripheral vascular resistance
10
Damage of cell by protein mechanism leads to:
activation of chaperons
11
Choose the condition of saturation of gases:
high atmospheric pressure
12
Characteristic feature of burn shock:
massive loss of plasma
13
Choose the cause of hemorrhagic syndrome during acute radiation sickness?
thrombocytopenia
14
Select the genes that controls passage of G1 phase to the S phase in cellular cycle: 1) Rb 2) p53 3) ERB-1 4) N-RAS 5) K-RAS 6) TGF-β
1,2,6
15
Choose the type of hypoxia accompanied with increasing of PvO2:
tissue
16
In this type of extreme states the primary changes occur in nervous system:
traumatic shock
17
Choose the factor which influences only in the beginning of disease:
ionizing radiation
18
Determine the changes in electrolyte metabolism during extreme states: 1) Increasing of intracellular Na+ 2) Increasing of extracellular K+ 3) Increasing of intracellular Mg2+ 4) Increasing of extracellular Na+ 5) Increasing of intracellular Ca2+
1,2,5
19
What does the semiotic mean?
teaching about signs and mechanisms of development of diseases
20
Choose the incorrect version:
in erectile stage of shock hypocatecholaminemia develops
21
Select the cause of infectious complication during acute radiation disease:
leukopenia
22
Select the incorrect version:
at first lymphocytes emigrate to the focus of inflammation
23
Choose the outcome of disease. 1) Stomach ulcer 2) Relapse 3) Agony 4) Terminal pause 5) Death
2, 5
24
Similar feature of tissue hypoxia and hemic hypoxia:
development of non-gaseous acidosis
25
Select the changes of nervous system during torpid stage of burn shock.
inhibition activity of brain cortex and subcortical nucleus
26
Choose the outcomes of the disease:
recovery, relapse, death, transition to the chronic form
27
Select that is characteristic for “lazy” leukocyte syndrome:
disturbance polimeration of actin microfilament in phagocytes
28
Select that is not characteristic for complete stage of acute radiation disease:
decreasing of residual nitrogen in the blood
29
What does the pathological process mean?
unity of damaging and compensation reactions of the organism after influence of pathogenic factors
30
What does the pathological reaction mean?
extraordinary reactions with short duration to stimulation
31
Choose the immune deficiency syndrome which accompanied with ataxia and teleangiectasia:
Louis-Bar syndrome
32
Choose the immunological marker of autoimmune hemolytic anemia:
autoantibodies against Rh-antigen
33
Characterize the biological death.
formation of irreversible changes in the cerebral cortex
34
Choose the stable defensive – adaptation reaction:
regeneration
35
Choose that is not characteristic for coma:
hyperreflexia
36
Choose the immediate mechanisms of sanogenesis. 1) Vomiting 2) Acceleration of erythropoiesis 3) Development of collaterals 4) Sneezing 5) Production of antibody
1, 4
37
Select the local sign of mechanical traumas.
pain
38
Which change is observed on cells under direct influence of ionizing radiation?
fragmentation of DNA molecules
39
Select that is not the cause of hypercalciemia:
decreasing reabsorption of calcium in renal tubules
40
Select the peripheral mechanisms of physiological tolerance: 1) Anergia 2) Immune deficiency states 3) Supression by regulatory T- cells 4) Excess activatipon of T-supressors 5) Apoptosis 6) Excess load of immune system by antigens
1,3,5
41
Respirator hypoxia is accompanied with: 1) Hypercapnia 2) Spasm of cerebral vessels 3) Gaseous acidosis 4) Hypocalcemia 5) Oxyhemoglobin dissociation curve shift to the right
1,3,5
42
Match the followings: I. Shock II. Collapse 1) Primary changes occur in nervous system 2) Vasodilator and hypovolemic types are distinguished 3) Primary changes occur in cardio-vascular system 4) Erectile and torpid phases are distinguished I II
1,4 2,3
43
Oxyhemoglobin dissociation curve shift to the right is observed during: 1) Thalassemia 2) Hypercapnia 3) Increasing of 2,3 diphosphoglycerate in erythrocytes 4) Chronic hypoxia 5) Increasing of body temperature
2,3,5
44
Protracted disturbance of functions and structures of the organs is called:
pathological state
45
Select the local change of disease:
increasing the volume of organ and tissues
46
Orthostatic collapse develops during:
sudden passage from bed regime to the vertical position
47
Determine the sequence of mechanisms during "shock kidneys": 1) Acute renal insufficiency 2) Decreasing of filtration pressure in renal glomeruli 3) Extreme irritant 4) Disturbances of filtration and reabsorption 5) Disturbance of blood circulation
3,5,2,4,1
48
Choose that is accompanied by local endogenous hypoxia: 1) Ischemia 2) Venous hyperemia 3) Mountain disease 4) High altitude disease 5) Stasis
1,2,5
49
Select that is not observed during emboli of portal vein:
increasing of circulated blood volume
50
The following changes are appeared in blood after a day of radiation (3. 5 Qr): erythrocytes - 4. 7·1012/l, hemoglobin – 120 g/l, leukocytes - 11·109 /l, thrombocytes - 270·109 /l. Blood smear: basophiles-1%, eosinophiles-3%, neutrophiles-81%, lymphocytes- 11%, monocytes-4%. For which period of acute radiation sickness all these changes are characteristic?
period of initial manifestations
51
What does the pathogenesis mean?
teaching about mechanisms of development, course and outcomes of diseases
52
Leads to development of "shock kidneys": 1) Hypervolemy 2) Postcapillary angiospasm 3) Hyperfiltration in glomeruli 4) Hypoperfusion of kidneys 5) Hyperoxemia
2,4
53
Formation and differentiation of T-lymphocytes is disturbed: 1) Di-George syndrome 2) West syndrome 3) Bruton syndrome 4) Mac-Kusic syndrome 5) Neselof syndrome
1,4,5
54
Select the mechanisms of development of auto-allergic diseases: 1) Disturbance of activation of complement sysytem 2) Hereditary predisposition 3) Infection 4) Disturbance metabolism of arachidonic acid 5) Disturbance of immunological tolerance 6) Non-adequate degranulation of must cells
2,3,5
55
Select that is characteristic for Costmann disease:
disturbance prolipheration of granulocytar stem cells in bone marrow
56
Choose the immunological marker of myasthenia gravis:
antibodies against acetylcholine receptors
57
Select the main sign of hypercalciemia:
nephrolithiasis
58
Which defensive-compensatory reaction develops during hyperthermia?
increasing of perspiration
59
Choose that is the reason of development of system circulatory hypoxia: 1) Venous hyperemia 2) Hypovolemy 3) Cardiac insufficiency 4) Stasis 5) Decreasing of vascular tonicity
2,3,5
60
Match the versions: Ways of spreading of pathogenic agents Diseases Hematogenic Х Lymphogenic Y Through the nervous fibers Z
X-sarcoma, Y-cancer disease, Z-tetanus viruses
61
Select the pathological states: 1) Scar 2) Gastritis 3) Gastric ulcer 4) Birthmark
1, 4
62
Select that is not characteristic for crash syndrome:
hemodilution
63
Select the main reason of hemolysis during burn disease:
entering of toxic substances into the blood from injured tissues
64
Which part of nervous system is more sensitive to hypoxia?
cerebral cortex
65
Difference of torpid phase of shock from erectile:
hyporeflexia is observed
66
Chronic hypoxia develops during: 1) Heart defects 2) Poisoning with cyanides 3) Iron deficiency anemia 4) Asphyxia 5) Cardiac asthma
1,3
67
The main link of pathogenesis:
dilation arterioles in arterial hyperemia
68
Select that is not characteristic for exhaustion stage of burn disease:
hypertrophy of adrenal cortex
69
Select the defensive-compensatory mechanism that prevents ionizing radiation:
activation of DNA reparation system
70
Characterize the latent period of diseases.
the period occurred before appearance of the first symptoms of disease
71
Select the sequence of pancytopenia during acute radiation disease:
lymphocytopenia, neutropenia, thrombocytopenia, anemia
72
The type of collapse developing during insufficiency of adrenal gland:
vasodilatation
73
Hypoosmolar hyperhydration is observed during:
increasing secretion of antidiuretuc hormone
74
Select the typical pathological processes: 1) Diabetes mellitus 2) Gastritis 3) Cell injury 4) Fever
3, 4
75
Clinical death is:
A period of temporary stopping of the vital functions
76
What does the vicious circle mean?
Causative-result interrelations replay each other in a such way, that after some sequence of processes the pathogenical mechanisms are aggravated
77
Choose that is the reason of development of centralization of blood circulation during hypoxia:
activation of symphato-adrenal system
78
Match the followings: The reasons of coma: I. Exogenous II. Endogenous a) neurotropic viruses b) ischemic insult c) starvation d) hypoinsulinism e) insufficiency of adrenal gland I II
a, c b, d, e
79
Characterize the biological death.
formation of irreversible changes in the cerebral cortex
80
Select that is characteristic for agony stage of terminal state:
Qasping respiration
81
Select the main change of pathological process which leads to the development of all other stages:
main link of pathogenesis
82
Select the chemotaxins: 1) Bacterial lypoipolysacharides 2) C-reactive protein 3) IL-8 4) IgG 5) PAF
1, 3, 5
83
Choose the pathological states. 1) Inflammation 2) The state after amputation 3) Fever 4) Scar after burn 5) Birthmark
2, 4, 5
84
Select that is characteristic for Recklinghausen disease:
neurogenic tumors that develops along of nervous fibers
85
Choose that is not belong to the microcirculatory changes during collapse:
hypervolemy
86
Select that is not characteristic for daltonism:
inherits by autosomal recessive way
87
Select the main sign of hypernatriemia:
arterial hypertension
88
Choose the immune deficiency syndrome which accompanied with exema and thrombocytopenia:
Wiskott-Aldrige syndrome
89
Choose that is not autoimmune disease:
Glanzmann-Riniker syndrome
90
Select that is not characteristic for desaturation:
increasing dissolving of gaseous in the blood
91
Select the correct sequences of the stages of disease:
latent, prodromal, the period of clinical manifestations, outcome
92
Choose that is not belong to the pathogenetic therapy of comatose states:
using of antidotes
93
Select the base of pathogenetic therapy of allergic disease:
inhibition synthesis of antibodies
94
Choose the reason why B-lymphocytes can’t recognize antigens in AIDS:
due to damaging of CD4 + Th2 cells
95
Select irreversible change during cell injury:
damage of lyzosomal membrane
96
Select that is not characteristic for agammaglobulinemia:
inherits by autosomal dominant way
97
Select that is characteristic for erectile stage of burn shock:
increasing activity of circulatory system
98
Choose the characteristic features of the typical pathological processes ?
pathological processes is a poly- etiological, mono- pathogenetical and has general regularities of development
99
Prolypherative inflammation is not observed during:
absesses
100
Choose the target cells of AIDS virus :
CD4+ lymphocytes