問題一覧
1
Select that is characteristic for agony stage of terminal state:
Qasping respiration
2
Characterize the biological death.
formation of irreversible changes in the cerebral cortex
3
Select the cause of infectious complication during acute radiation disease:
leukopenia
4
Select that is not characteristic for crash syndrome:
hemodilution
5
Select that is not characteristic for desaturation:
increasing dissolving of gaseous in the blood
6
Select that is not characteristic for complete stage of acute radiation disease:
decreasing of residual nitrogen in the blood
7
Which change is observed on cells under direct influence of ionizing radiation?
fragmentation of DNA molecules
8
Select the defensive-compensatory mechanism that prevents ionizing radiation:
activation of DNA reparation system
9
Select the sequence of pancytopenia during acute radiation disease:
lymphocytopenia, neutropenia, thrombocytopenia, anemia
10
Choose the cause of hemorrhagic syndrome during acute radiation sickness?
thrombocytopenia
11
Select that is not characteristic for agammaglobulinemia:
inherits by autosomal dominant way
12
Select that is not characteristic for daltonism:
inherits by autosomal recessive way
13
Select that is not characteristic for expansion of triplet nucleotides:
inherits by X-chromosomal recessive way
14
The following changes are appeared in blood after a day of radiation (3. 5 Qr): erythrocytes - 4. 7·1012/l, hemoglobin – 120 g/l, leukocytes - 11·109 /l, thrombocytes - 270·109 /l. Blood smear: basophiles-1%, eosinophiles-3%, neutrophiles-81%, lymphocytes- 11%, monocytes-4%. For which period of acute radiation sickness all these changes are characteristic?
period of initial manifestations
15
Select that is characteristic for Recklinghausen disease:
neurogenic tumors that develops along of nervous fibers
16
Select that is characteristic for burn disease:
increasing of ESR
17
Select the main reason of hemolysis during burn disease:
entering of toxic substances into the blood from injured tissues
18
Select that is characteristic for erectile stage of burn shock:
increasing activity of circulatory system
19
Select the changes of nervous system during torpid stage of burn shock.
inhibition activity of brain cortex and subcortical nucleus
20
Select that is not characteristic for exhaustion stage of burn disease:
hypertrophy of adrenal cortex
21
Select that is not the cause of hypercalciemia:
decreasing reabsorption of calcium in renal tubules
22
Select irreversible change during cell injury:
damage of lyzosomal membrane
23
Select the incorrect version:
at first lymphocytes emigrate to the focus of inflammation
24
Choose the condition of saturation of gases:
high atmospheric pressure
25
Select the chemotaxins: 1) Bacterial lypoipolysacharides 2) C-reactive protein 3) IL-8 4) IgG 5) PAF
1, 3, 5
26
Oxyhemoglobin dissociation curve shift to the left is observed during: 1) Hypocapnia 2) Increasing of 2,3 diphosphoglycerate in erythrocytes 3) Thalassemia 4) Decreasing of body temperature 5) Hypercapnia
1,3,4
27
Oxyhemoglobin dissociation curve shift to the right is observed during: 1) Thalassemia 2) Hypercapnia 3) Increasing of 2,3 diphosphoglycerate in erythrocytes 4) Chronic hypoxia 5) Increasing of body temperature
2,3,5
28
Similar feature of tissue hypoxia and hemic hypoxia:
development of non-gaseous acidosis
29
Respirator hypoxia is accompanied with: 1) Hypercapnia 2) Spasm of cerebral vessels 3) Gaseous acidosis 4) Hypocalcemia 5) Oxyhemoglobin dissociation curve shift to the right
1,3,5
30
Hemic hypoxia develops during:
poisoning with bertole salt
31
Choose the type of hypoxia accompanied with increasing of PvO2:
tissue
32
Chronic hypoxia develops during: 1) Heart defects 2) Poisoning with cyanides 3) Iron deficiency anemia 4) Asphyxia 5) Cardiac asthma
1,3
33
Choose that is accompanied by local endogenous hypoxia: 1) Ischemia 2) Venous hyperemia 3) Mountain disease 4) High altitude disease 5) Stasis
1,2,5
34
Choose that is the reason of development of circulatory hypoxia of vascular origin:
insufficiency of adrenal glands
35
Choose that is the reason of development of system circulatory hypoxia: 1) Venous hyperemia 2) Hypovolemy 3) Cardiac insufficiency 4) Stasis 5) Decreasing of vascular tonicity
2,3,5
36
Choose that is the reason of development of centralization of blood circulation during hypoxia:
activation of symphato-adrenal system
37
Determine the changes in electrolyte metabolism during extreme states: 1) Increasing of intracellular Na+ 2) Increasing of extracellular K+ 3) Increasing of intracellular Mg2+ 4) Increasing of extracellular Na+ 5) Increasing of intracellular Ca2+
1,2,5
38
Difference of torpid phase of shock from erectile:
hyporeflexia is observed
39
Characteristic feature of burn shock:
massive loss of plasma
40
Choose that is the reason of development of vasodilatory collapse:
decreasing of peripheral vascular resistance
41
Match the followings: The reasons of coma: I. Exogenous II. Endogenous a) neurotropic viruses b) ischemic insult c) starvation d) hypoinsulinism e) insufficiency of adrenal gland I II
a, c b, d, e
42
Match the followings: I. Shock II. Collapse 1) Primary changes occur in nervous system 2) Vasodilator and hypovolemic types are distinguished 3) Primary changes occur in cardio-vascular system 4) Erectile and torpid phases are distinguished I II
1,4 2,3
43
Choose the incorrect version:
in erectile stage of shock hypocatecholaminemia develops
44
In this type of extreme states the primary changes occur in nervous system:
traumatic shock
45
Choose that is not characteristic for coma:
hyperreflexia
46
Leads to development of "shock kidneys": 1) Hypervolemy 2) Postcapillary angiospasm 3) Hyperfiltration in glomeruli 4) Hypoperfusion of kidneys 5) Hyperoxemia
2,4
47
Choose the pathogenetic factor of collapse:
decreasing of peripheral vascular resistance
48
Choose that is not belong to the pathogenetic therapy of comatose states:
using of antidotes
49
Orthostatic collapse develops during:
sudden passage from bed regime to the vertical position
50
The type of collapse developing during insufficiency of adrenal gland:
vasodilatation
51
Determine the sequence of mechanisms during "shock kidneys": 1) Acute renal insufficiency 2) Decreasing of filtration pressure in renal glomeruli 3) Extreme irritant 4) Disturbances of filtration and reabsorption 5) Disturbance of blood circulation
3,5,2,4,1
52
Choose that is not belong to the microcirculatory changes during collapse:
hypervolemy
53
Choose the correct version:
collapse is accompanied by decreasing of venous pressure
54
Formation and differentiation of T-lymphocytes is disturbed: 1) Di-George syndrome 2) West syndrome 3) Bruton syndrome 4) Mac-Kusic syndrome 5) Neselof syndrome
1,4,5
55
Choose the immune deficiency syndrome which accompanied with exema and thrombocytopenia:
Wiskott-Aldrige syndrome
56
Choose the target cells of AIDS virus :
CD4+ lymphocytes
57
Choose the immune deficiency syndrome which accompanied with ataxia and teleangiectasia:
Louis-Bar syndrome
58
Choose the immune deficiency syndrome which accompanied with cleft palate and coarctation of aorta:
Di-George syndrome
59
Choose the reason why B-lymphocytes can’t recognize antigens in AIDS:
due to damaging of CD4 + Th2 cells
60
Choose the immunological marker of autoimmune hemolytic anemia:
autoantibodies against Rh-antigen
61
Choose the immunological marker of myasthenia gravis:
antibodies against acetylcholine receptors
62
Choose that is not autoimmune disease:
Glanzmann-Riniker syndrome
63
Select the peripheral mechanisms of physiological tolerance: 1) Anergia 2) Immune deficiency states 3) Supression by regulatory T- cells 4) Excess activatipon of T-supressors 5) Apoptosis 6) Excess load of immune system by antigens
1,3,5
64
Select the mechanisms of development of auto-allergic diseases: 1) Disturbance of activation of complement sysytem 2) Hereditary predisposition 3) Infection 4) Disturbance metabolism of arachidonic acid 5) Disturbance of immunological tolerance 6) Non-adequate degranulation of must cells
2,3,5
65
Select the genes that controls passage of G1 phase to the S phase in cellular cycle: 1) Rb 2) p53 3) ERB-1 4) N-RAS 5) K-RAS 6) TGF-β
1,2,6
66
Hypoosmolar hyperhydration is observed during:
increasing secretion of antidiuretuc hormone
67
Pathological hypoglycemia is not observed during:
pheochromacytoma
68
Select the main sign of hypercalciemia:
nephrolithiasis
69
Select the main sign of hypernatriemia:
arterial hypertension
70
Select that is characteristic for Costmann disease:
disturbance prolipheration of granulocytar stem cells in bone marrow
71
Select that is characteristic for “lazy” leukocyte syndrome:
disturbance polimeration of actin microfilament in phagocytes
72
Prolypherative inflammation is not observed during:
absesses
73
Select that is not observed during emboli of portal vein:
increasing of circulated blood volume
74
Damage of cell by protein mechanism leads to:
activation of chaperons
75
Choose the characteristic features of the typical pathological processes ?
pathological processes is a poly- etiological, mono- pathogenetical and has general regularities of development
76
Choose the correct sequence of destroying of organs and tissues in the process of death.
cerebral cortex, subcortical nuclei, brain stem, spinal cord, parenchymatous organs
77
What does the semiotic mean?
teaching about signs and mechanisms of development of diseases
78
What does the etiology mean?
teaching about reasons and conditions of diseases
79
What does the pathogenesis mean?
teaching about mechanisms of development, course and outcomes of diseases
80
What does the pathological process mean?
unity of damaging and compensation reactions of the organism after influence of pathogenic factors
81
What does the vicious circle mean?
Causative-result interrelations replay each other in a such way, that after some sequence of processes the pathogenical mechanisms are aggravated
82
What does the pathological reaction mean?
extraordinary reactions with short duration to stimulation
83
The main link of pathogenesis:
dilation arterioles in arterial hyperemia
84
Choose the outcomes of the disease:
recovery, relapse, death, transition to the chronic form
85
Select the correct sequences of the stages of disease:
latent, prodromal, the period of clinical manifestations, outcome
86
Select the main change of pathological process which leads to the development of all other stages:
main link of pathogenesis
87
Protracted disturbance of functions and structures of the organs is called:
pathological state
88
Characterize the latent period of diseases.
the period occurred before appearance of the first symptoms of disease
89
Select the local change of disease:
increasing the volume of organ and tissues
90
Select the typical pathological processes: 1) Diabetes mellitus 2) Gastritis 3) Cell injury 4) Fever
3, 4
91
Select the pathological states: 1) Scar 2) Gastritis 3) Gastric ulcer 4) Birthmark
1, 4
92
Match the versions: Ways of spreading of pathogenic agents Diseases Hematogenic Х Lymphogenic Y Through the nervous fibers Z
X-sarcoma, Y-cancer disease, Z-tetanus viruses
93
Choose the pathological states. 1) Inflammation 2) The state after amputation 3) Fever 4) Scar after burn 5) Birthmark
2, 4, 5
94
Choose the diseases. 1) Lung cancer 2) Edema 3) Appendicitis 4) Hypoxia 5) Tonsillitis
1, 3, 5
95
Choose the outcome of disease. 1) Stomach ulcer 2) Relapse 3) Agony 4) Terminal pause 5) Death
2, 5
96
Choose the immediate mechanisms of sanogenesis. 1) Vomiting 2) Acceleration of erythropoiesis 3) Development of collaterals 4) Sneezing 5) Production of antibody
1, 4
97
Choose the factor which influences only in the beginning of disease:
ionizing radiation
98
Select the base of pathogenetic therapy of allergic disease:
inhibition synthesis of antibodies
99
Choose the relative stable defensive – adaptation reaction:
reaction elements of connective tissue
100
Choose the stable defensive – adaptation reaction:
regeneration