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METABOLIC DISORDER

  • Jef Marc Valencia

    • 問題数 74 • 3/19/2025

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  • 1

    Categories of metabolic disorders

    OVERFLOW, RENAL

  • 2

    Category of metabolic disorder resulting from destruction of a normal metabolic pathway that causes increased plasma concentrations of amino acids

    OVERFLOW

  • 3

    Category of metabolic disorder due to defective tubular reabsorption of amino acids

    RENAL

  • 4

    Term refering failure to inherit a gene that codes for a particular enzyme

    INBORN ERROR OF METABOLISM

  • 5

    Newborn screening test sample

    PHENYLKETONURIA, MAPLE SYRUP URINE DISEASE, G6PD, CYSTINURIA, CYSTINOSIS

  • 6

    Major inherited disorders

    PHENYLKETONURIA, TYROSYLURIA, ALKAPTONURIA

  • 7

    The most well known of the aminoacidurias

    PHENYLKETONURIA

  • 8

    Gene failed to be inherited in phenylketonuria

    PHENYLALANINE HYDROXYLASE

  • 9

    Urine odor in Phenylketonuria

    MOUSY

  • 10

    Phenylketonuria may lead to___when not treated

    MENTAL RETARDATION

  • 11

    Screening test for Phenylketonuria

    FERRIC CHLORIDE TUBE TEST, PHENISTIX STRIP, GUTHRIE BACTERIAL INHIBITION TEST

  • 12

    Screening test for Phenylketonuria that exhibits +blue-green color

    FERRIC CHLORIDE TUBE TEST

  • 13

    Screening test for Phenylketonuria which exhibits + gray to gray green color

    PHENISTIX STRIP

  • 14

    The most well known phenylketonuria test

    GUTHRIE BACTERIAL INHIBITION TEST, GUTHRIE MICROBIAL INHIBITION ASSAY

  • 15

    Inhibitor for Guthre inhibition test

    BETA 2 THIENYLALANINE

  • 16

    Bacteria used in Guthrie Inhibition Test

    BACILLUS SUBTILIS

  • 17

    Accumulation of excess tyrosine in the plasma producing a urinary overflow

    TYROSYLURIA

  • 18

    Tyrosyluria type 1 failed gene decoded

    FUMARYLACETOACETATE HYDROLASE

  • 19

    Tyrosyluria type 2 failed gene decoded

    TYROSINE AMINOTRANSFERASE

  • 20

    Tyrosyluria type 3 failed gene decoded

    P-HYDROXYPHENYLPYRUVIC ACID DIOXYGENASE

  • 21

    Tyrosyluria are also seen in patients w/ severe

    LIVER DISEASE

  • 22

    Tyrosyluria urine odor

    RANCID BUTTER

  • 23

    Screening test for Tyrosyluria

    NITROSONAPHTOL

  • 24

    Confirmatory test for Tyrosyluria

    CHROMATOGRAPHY

  • 25

    Deficiency in homogentisic acid oxidase leading to increased homogentisic acid

    ALKAPTONURIA

  • 26

    Alkaptonuria produces ______ in body tissues that can lead to arthritis, liver and cardiac problems

    BROWN PIGMENT DEPOSIT

  • 27

    Screening test for Alkaptonuria

    FERRIC CHLORIDE TUBE TEST, BENEDICTS TEST, ALKALINIZATION OF FRESH URINE

  • 28

    Increased urinary melanin that produces a darkening of urine indicating malignant melanoma

    MELANURIA

  • 29

    Screening test for melanuria

    FERRIC CHLORIDE TUBE TEST, SODIUM NITROPRUSSIDE TEST, EHRLICH TEST

  • 30

    The branched chain amino acids differ form the other amino acids by having a methyl (-CH3) group that branches from the main aliphatic carbon chain

    BRANCHED CHAIN AMINOACIDURIA

  • 31

    Clinical findings of branched chain amino acids

    KETONURIA

  • 32

    What are the major groups of branched chain aminoacidurias

    ACCUMULATION OF ONE OR MORE EARLY AMINO ACID DEGRADATION PRODUCT, ORGANIC ACIDEMIA

  • 33

    Major group of branched chain aminoacidurias refering to accumulation of organic acids produced further down in the amino acid metabolic pathway leading to excretion of organic acids in urine

    ORGANIC ACIDEMIA

  • 34

    Most c'mon Inborn Error of Metabolism in the Philippines

    MAPLE SYRUP URINE DISEASE

  • 35

    What are the enzymes failed to metabolized during maple syrup urine disease

    LEUCINE, ISOLEUCINE, VALINE

  • 36

    Urine odor of Maple Syrup Urine Disease

    CARAMELIZED SUGAR, MAPLE SYRUP, CURRY

  • 37

    Maple Syrup Urine Disease causes when left untreated

    MENTAL RETARDATION, CONVULSION, ACIDOSIS, HYPOGLYCEMIA

  • 38

    Screening test for Maple syrup Urine disease

    2,4 DINITROPHENYLHYDRAZINE, FERRIC CHLORIDE TUBE TEST

  • 39

    Generalized symptoms of organic acidemias

    VOMITING W/ METABOLIC ACIDOSIS, HYPOGLYCEMIA, KETONURIA, INCREASED SERUM AMMONIA

  • 40

    Most c'monly encountered organic acidemias disorders

    ISOVALERIC ACIDEMIA, PROPIONIC ACIDEMIA, METHYLMALONIC ACIDEMIA

  • 41

    Most c'monly encountered organic acidemias disorder exhibiting a sweaty feet urine odor

    ISOVALERIC ACIDEMIA

  • 42

    Most c'monly encountered organic acidemias disorder detected using p-nitroaniline test

    METHYLMALONIC ACIDEMIA

  • 43

    It is the increased urinary excretion of the metabolites indican and 5-hydroxyindoleacetic acid

    TRYPTOPHAN AMINOACIDURIA

  • 44

    Argentaffinoma refers t the increased w/_____, a metabolite of serotonin

    5-HYDROXYINDOLEACETIC ACID

  • 45

    Increased amounts of tryptophan which are converted to indole

    INDICANURIA

  • 46

    Screening test for indicanuria

    OBERMAYERS TEST

  • 47

    Indicanuria seen in intestinal disorders like

    OBSTRUCTION, PRESENCE OF ABNORMAL BACTERIA, HARTNUP DISEASE

  • 48

    Refering to blue diaper syndrome or acid blue diaper syndrome due to indicanuria

    HARTNUP DISEASE

  • 49

    Urine color of Hartnup disease

    INDIGO BLUE

  • 50

    Degradation product of serotonin produced from tryptophan by argentaffin cells in the intestines

    5-HYDROXYINDOLEACETIC ACID

  • 51

    Tumors that may appear due to increased in 5-hydroxyindoleacetic acid

    ARGENTAFFIN CELL TUMOR

  • 52

    Screening test for 5-hydroxyindoleacetic acid

    FERRIC CHLORIDE TUBE TEST, NITROSONAPHTOL W/ NITROUS ACID

  • 53

    What is being avoided nutrient content of food for patient preparation of 5-hydroxyindoleacetic acid

    SEROTONIN

  • 54

    A condition marked by elevated amounts of the amino acids cystine in tthe urine due to the inability of the renal tubules to reabsorb cystine filtered by the glomerulus

    CYSTINURIA

  • 55

    Cystinuria odor of urine

    SULFUR

  • 56

    What amino acid being not reabsorbed during cystinuria

    CYSTINE, ORNITHINE, LYSINE, ARGININE

  • 57

    Refering to cystine deposits in many areas of the body (BM, Cornea, Lymph nodes, and internal organs)

    CYSTINOSIS

  • 58

    Failure of the gene that codes for an enzyme responsile for cystine metabolism

    CYSTINOSIS

  • 59

    Tests for cystinuria and and cystinosis

    BRANDS MODIFICATION OF LEGALS NITROPRUSSIDE TEST, THIN LAYER OR ION EXCHANGE CHROMATOGRAPHY, HIGH VOLTAGE ELECTROPHORESIS

  • 60

    Defect in the metabolism of the amino acid methionine leading to increased homocysteine

    HOMOCYSTINURIA

  • 61

    What is the gene being failed to decode in Homocystinuria

    CYSTATHIONE BETA SYNTHASE

  • 62

    Urine color during porphyrin disorders

    RED, PURPLE, BURGUNDY RED, PURPLISH RED, PORT WINE

  • 63

    Porphyrin disorders are usually caused by

    LEAD POISONING

  • 64

    Urine color when porphyrin disorder is due to lead poisoning

    COLORLESS

  • 65

    CDC recommended test for lead poisoning

    FREE ERYTHROCYTE PORPHYRIN

  • 66

    Sample used for Free Erythrocyte Porphyrin

    WHOLE BLOOD

  • 67

    Accumulation of Incomplete Metabolized Polysaccharide portions in lysosome

    MUCOPOLYSACCHARIDE DISORDER

  • 68

    Accumulation of mucopolysaccharide in the cornea

    HURLER

  • 69

    Accumulation of mucopolysaccharide that causes skeletal structure abnormality and severe mental retardation

    HUNTER

  • 70

    Accumulation of mucopolysaccharide which causes mental retardation only

    SANFILIPPO SYNDROME

  • 71

    A purine disorder which causes massive excretion of uric acid crystals in the urine caused by a failure of inherited gene that will produce______

    LESCH NYHAN SYNDROME

  • 72

    Findings of Lesch Nyhan disease

    ORANGE SAND IN DIAPER

  • 73

    Test for Mucopolysaccharide Disorder

    CETYL TRIMETHYL AMMONIUM BROMIDE TEST

  • 74

    CTAB test positive result

    WHITE TURBIDITY

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    問題数 632025/04/22

    SPERM 2

    問題数 692025/04/22

    Fructose test table

    問題数 52025/04/22

    Sperm motility table

    問題数 82025/04/22

    PROTOZOAN

    問題数 812025/04/24

    CSF

    問題数 962025/04/29

    AMOEBA

    問題数 222025/04/29

    MCQ-CHEMICAL EXAMINATION OF URINE PART 2

    問題数 792025/05/03

    PERICARDIAL FLUID

    問題数 662025/05/04

    MCQ-SPERM

    問題数 592025/05/03

    MCQ-SPERM 2

    問題数 882025/05/03

    MCQ-AMNIOTIC FLUID

    問題数 732025/05/08

    HEMOFLAGELLATES

    問題数 682025/05/04

    Sex disorder

    問題数 602025/05/05

    NEMATODES

    問題数 62025/05/06

    MCQ-PERICARDIAL FLUID

    問題数 592025/05/11

    PHASMID NEMATODES

    問題数 52025/05/06

    HOOKWORMS

    問題数 92025/05/06

    MCQ-CSF

    問題数 942025/05/03

    BLOOD AND TISSUE NEMATODE

    問題数 82025/05/06

    PLATYHELMINTHS

    問題数 132025/05/06

    MCQ-CSF2

    問題数 242025/05/03

    TREMATODES

    問題数 72025/05/06

    INTRODUCTION

    問題数 362025/06/10

    INTRODUCTION TABLE

    問題数 412025/06/10

    CLASSFICATION OF ENZYME

    問題数 472025/06/11

    ENZYME VARIANTS

    問題数 412025/06/11

    FACTORS AFFECTING ENZYME ACTIVITY

    問題数 902025/06/12

    INTRODUCTION TO ENZYMOLOGY-MCQ

    問題数 412025/06/26

    CLASS AND VARIANT OF ENZYME-MCQ

    問題数 772025/06/26

    PITUITARY GLAND PART 2

    問題数 52025/07/04

    THYROID GLAND

    問題数 712025/07/04

    PARATHYROID GLAND

    問題数 122025/07/04

    ADRENAL GLAND

    問題数 772025/07/04

    SEX GLANDS

    問題数 352025/07/04

    OTHER GLANDS

    問題数 82025/07/04

    ACID BASE BALANCE

    問題数 512025/07/10

    TRACE ELEMENT

    問題数 792025/07/10

    VITAMINS

    問題数 272025/07/10

    TUMOR MARKERS

    問題数 252025/07/10

    TOXICOLOGY

    問題数 722025/07/13

    DRUG OF ABUSE

    問題数 952025/07/13

    TOXINS

    問題数 572025/07/13

    TDM

    問題数 942025/07/13

    ENDOCRINOLOGY

    問題数 962025/07/16

    ENDROCRINOLOGY PART 2

    問題数 462025/07/16

    FACTORS AFFECTING ENZYME ACTIVITY-MCQ

    問題数 892025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ

    問題数 992025/07/17

    ENZYME OF CLINICAL SIGNIFICANCE-MCQ2

    問題数 872025/07/18

    MEDICAL TERMINOLOGIES

    問題数 362025/08/17

    INTRODUCTION TO HEMA 1

    問題数 292025/08/17

    LABORATORY SAFETY

    問題数 232025/08/18

    TERMINOLOGIES

    問題数 512025/08/21

    LABORATORY 1

    問題数 182025/08/22

    LABORATORY 3

    問題数 532025/08/22

    HEMATOPOIESIS

    問題数 622025/08/23

    THEORIES ON BLOOD FORMATION

    問題数 552025/08/30

    ERYTHROPOIESIS

    問題数 462025/08/30

    LEUKOPOIESIS

    問題数 1002025/08/30

    LEUKOPOIESIS II AND MONOPOIESIS

    問題数 422025/09/01

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/24

    MYCOLOGY PROPER

    問題数 712025/09/01

    FUNGAL PATHOGENESIS

    問題数 352025/09/01

    CLASSIFICATION OF FUNGI

    問題数 452025/09/06

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS

    問題数 742025/09/06

    MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 542025/09/06

    Mind mapping

    問題数 92025/09/07

    INTRODUCTION TO MYCOLOGY MCQ

    問題数 322025/09/13

    MYCOLOGY PROPER MCQ

    問題数 592025/09/13

    FUNGAL PATHOGENESIS MCQ

    問題数 372025/09/13

    CLASSIFICATION OF FUNGI MCQ

    問題数 332025/09/13

    SPECIMEN COLLECTION, CULTURE, AND COLONIAL CHARACTERISTICS MCQ

    問題数 742025/09/13

    MCQ-MICROSCOPIC STUDY, CULTURE EXAMINATION, AND PRESERVATION OF FUNGI

    問題数 532025/09/14

    THE SUPEFICIAL FUNGI

    問題数 342025/09/12

    THE CUTANEOUS FUNGI

    問題数 582025/09/13

    SUBCUTANEOUS FUNGI

    問題数 552025/09/13

    SYSTEMIC FUNGI

    問題数 282025/09/13

    LYMPHOPOIESIS

    問題数 442025/09/07

    MEGAKARYOPOIESIS

    問題数 342025/09/07

    INTRODUCTION TO HEMA1 MCQ

    問題数 452025/09/10

    HEMATOPOIESIS

    問題数 582025/09/14

    THEORIES ON BLOOD FORMATION

    問題数 462025/09/14

    ERYTHROPOIESIS MCQ

    問題数 412025/09/14

    LEUKOPOIESIS MCQ

    問題数 942025/09/10

    LEUKOPOIESIS II AND MONOPOIESIS MCQ

    問題数 392025/09/14

    LYMPHOPOIESIS MCQ

    問題数 392025/09/10

    MEGAKARYOPOIESIS MCQ

    問題数 392025/09/10

    BLOOD COLLECTION

    問題数 352025/09/10

    LABORATORY SAFETY

    問題数 212025/09/17

    LABORATORY 1

    問題数 162025/09/17

    LABORATORY 3

    問題数 472025/09/17

    BLOOD COLLECTION MCQ

    問題数 792025/09/17

    DEMATIACEOUS OPPORTUNISTIC FUNGI

    問題数 522025/09/30

    PENICILLUS

    問題数 212025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA IN CLUSTER

    問題数 162025/10/08

    HYALINE SEPTATE GROUP W/ CONIDIA BORNE SINGLY

    問題数 122025/10/08

    ZYGOMYCETE/HYALINE SEPTATE GROUP

    問題数 492025/10/08

    YEAST AND YEAST LIKE ORGANISMS

    問題数 722025/10/15

    HEMOCYTOMETRY

    問題数 832025/10/03

    HEMOGLOBIN

    問題数 1002025/10/04

    HEMOGLOBIN PART 2

    問題数 262025/10/05

    OXYGEN DISSOCIATION CURVE

    問題数 282025/10/14

    QUANTIFICATION OF HBF

    問題数 762025/10/12

    YEAST AND YEAST LIKE ORGANISMS

    問題数 702025/10/26