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CLINICAL CHEMISTRY.
  • Yves Laure Pimentel

  • 問題数 100 • 3/10/2024

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    問題一覧

  • 1

    Sweat test in cystic fibrosis High in what electrolytes

    Na* and Cl

  • 2

    substance that can yield a hydrogen ion

    Acid

  • 3

    mmhg , The normal difference between alveolar and arterial PO2 (PAO2—PaO2 difference)

    10 mmHg

  • 4

    RATIO? of HCO; to H2CO; (total dissolved carbon dioxide)

    20:1

  • 5

    represents the combined hydration and dissociation constants for CO2 in blood at 37°C

    6.1

  • 6

    formula: Getting dissolved carbon dioxide (dCO,)

    pCO2 x 0.03

  • 7

    associated with both metabolic and respiratory alkalosis

    Hypokalemia

  • 8

    only anticoagulant that does not alter the pH of blood

    Heparin

  • 9

    anticoagulant Open heart surgery

    Heparin

  • 10

    anticoagulant For cardiopulmonary bypass

    Heparin

  • 11

    Storage time for ABG should be no more than

    30 min

  • 12

    exposure of a normal arterial blood sample to room air PO2 ?, PCO2 ?>, pH ?

    PO2 increased PCO2 decreased pH increased

  • 13

    how many pH decrease/each Celsius above 37°C

    .015

  • 14

    Inhibit GH secretion (6)

    BI GATE B-agonist (epinephrine) Insulin def Glucose loading a-blockers (phentolamine) Thyroxine def Emotional/Psychogenic stress

  • 15

    Gold standard for GH deficiency

    Insulin Tolerance Test

  • 16

    Confirmatory for acromegaly

    GLUCOSE SUPPRESSION TEST (OGTT 100g glucose)

  • 17

    Not a hormone-producing-gland

    Posterior pituitary gland

  • 18

    Secretes Oxytocin and ADH

    Posterior pituitary gland

  • 19

    Milk ejection and uterine contraction

    Oxytocin

  • 20

    Water retention

    ADH

  • 21

    Low ADH/ADH resistant — Diabetes insipidus

    ADH

  • 22

    High ADH — SIADH

    ADH

  • 23

    Thyroid location

    Lower anterior neck

  • 24

    Majority of T4 is bound to

    TBG —a globulin

  • 25

    Most potent Thyroid hormone

    T3

  • 26

    Predominant Thyroid hormone

    T4

  • 27

    Test used to Differentiate Primary from secondary Hypothyroidism

    TSH Test

  • 28

    If a screening TSH is high, which test is likely to be ordered next?

    FT4

  • 29

    the most reliable indicator of thyroid status in sick individuals

    FT4

  • 30

    Increase protein will

    increase TBG

  • 31

    Antithyroglobulin autoantibodies — interference . what assay?

    TG- Thyroglobulin assay

  • 32

    Not a part of thyroid function test

    TG assay

  • 33

    the MOST POTENT mineral corticoid (electro-regulating hormone)

    Aldosterone

  • 34

    this Increase in BP and BV (Blood volume) suppresses secretion of renin

    Aldosterone

  • 35

    Confirmatory test for Conn/primary hyperaldosteronism

    Saline suppression test

  • 36

    specimen: The most sensitive and specific screening test for excess cortisol prod using HPLC or GC-MS

    24 hr urine free cortisol

  • 37

    MOST WIDELY USED salivary cortisol test

    Overnight/rapid dexamethasone suppression test

  • 38

    The most sensitive and specific screening test for excess cortisol prod

    Low Dose dexamethasone Suppression test

  • 39

    spx MOST WIDELY USED salivary cortisol test

    Midnight plasma cortisol

  • 40

    GOLD STANDARD for secondary and tertiary hypocortisolism

    Insulin Tolerance Test (ITT)

  • 41

    First responders to stress

    Cathecholamines

  • 42

    Major metabolite of epinephrine

    VMA

  • 43

    Major metabolite of Dopamine

    HVA

  • 44

    has poor sensitivity and specificity (least helpful) in the diagnosis of pheochromocytoma

    Urinary VMA

  • 45

    Urinary VMA has poor sensitivity and specificity (least helpful) in the diagnosis of

    pheochromocytoma

  • 46

    Cardioprotective > assoc to CVD

    Estrogens

  • 47

    Present in both male and female

    Estradiol (E2)

  • 48

    SINGLE BEST HORMONE to determine whether OVULATION HAS OCCURRED

    Progesterone

  • 49

    causes infertility

    Stress

  • 50

    Stress causes

    infertility

  • 51

    diagnostic marker for Zollinger-Ellison Syndrome

    Gastrin

  • 52

    Gastrin diagnostic marker for

    Zollinger-Ellison Syndrome

  • 53

    Diagnostic marker for Carcinoid syndrome. (Argentaffinoma)

    5HIAA

  • 54

    5HIAA Diagnostic marker for

    Carcinoid syndrome. (Argentaffinoma)

  • 55

    Vitamin K (phylloquinone )deficiency

    Hemorrhage

  • 56

    ? deficiency Hemorrhage

    Vitamin K (phylloquinone )deficiency

  • 57

    Vitamin B6 deficiency

    Facial seborrhea

  • 58

    deficiency Facial seborrhea

    Vitamin B6 deficiency

  • 59

    Vit C deficiency

    Scurvy

  • 60

    deficiency Scurvy

    Vit C deficiency

  • 61

    it is the highest concentration of a drug obtained in the dosing interval

    Peak concentration

  • 62

    the lowest concentration of a drug obtained in the dosing interval

    Trough Concentration

  • 63

    is the specimen of choice for the determination of circulating concentrations of most drugs

    Serum or plasma

  • 64

    SPX is suitable for most drug analysis

    Heparinized plasma

  • 65

    Anticoagulant of Choice for TDM

    Sodium fluoride

  • 66

    the release of drug

    Liberation

  • 67

    transport of drug to the blood

    .Absorption

  • 68

    delivery of drug to the tissues ($.2019)

    Distribution

  • 69

    what do you call the chemical modification of drug by cells

    Metabolism

  • 70

    limination of drug or its metabolite

    Excretion

  • 71

    Treatment for Congestive heart failure

    Digoxin

  • 72

    are Nephrotoxic and ototoxic

    Aminoglycosides

  • 73

    Red man syndrome

    Vancomycin

  • 74

    Drug most often implicated in acquired aplastic anemia

    Chloramphenicol

  • 75

    for grand mal seizures

    Carbamazepine (Tegretol)

  • 76

    Drug of Choice for controlling Petit mal

    Ethosuximide (Zarontin)

  • 77

    treatment of manic-depressive illness (bipolar disorder)

    Lithium

  • 78

    Antiasthmatic

    Theophylline Theobromine

  • 79

    Theophylline Theobromine IS FOR?

    Anti asthmatic

  • 80

    Analgesics EXAMPLES

    ISAAAT Ibuprofen Salicylates/Aspirin/ acetylsalicylic acid Acetaminophen (Tylenol)

  • 81

    antibiotic which Inhibit cyclooxygenase

    Aspirin

  • 82

    antibiotic Assoc to Reye’s syndrome

    Aspirin

  • 83

    Most trace elements are of medical importance because excessive levels lead to

    toxicity

  • 84

    Trace no known biological purpose

    ME THA L CA A MErcury, THAllium, Lead, CAdmium, and Aluminum

  • 85

    elements that Has known biologic purpose

    Arsenic zinc, and copper

  • 86

    - necessary for normal methionine metabolism selenium, (m.23)

    Arsenic

  • 87

    as the detector - reference method for quantitative identification of most organic compounds

    gas chromatography coupled with a mass spectrometer (GC-MS)

  • 88

    is formed when yeast ferments sugar

    Alcohol

  • 89

    Most common abused drug

    Ethanol

  • 90

    ratio of >2 is highly specific for ethanol-related liver disease

    AST/ALT

  • 91

    AST/ALT —a ratio of >2 is highly specific for ethanol-related to what dse?

    liver disease

  • 92

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.01-0.05 " Stage of Alcohol Influence ?

    Subclinical

  • 93

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.03-0.12 " Stage of Alcohol Influence ?

    Euphoria

  • 94

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.09-0.25 " Stage of Alcohol Influence ?

    Excitement

  • 95

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.18-0.30 " Stage of Alcohol Influence ?

    Confusion

  • 96

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.25-0.40 " Stage of Alcohol Influence ?

    Stupor

  • 97

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.35-0.50 " Stage of Alcohol Influence ?

    Coma

  • 98

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.45+ " Stage of Alcohol Influence ?

    Death

  • 99

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) ? Stage of Alcohol Influence "Subclinical "

    0.01-0.05

  • 100

    Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) ? Stage of Alcohol Influence "Euphoria "

    0.03-0.12