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問題一覧
1
Sweat test in cystic fibrosis High in what electrolytes
Na* and Cl
2
substance that can yield a hydrogen ion
Acid
3
mmhg , The normal difference between alveolar and arterial PO2 (PAO2—PaO2 difference)
10 mmHg
4
RATIO? of HCO; to H2CO; (total dissolved carbon dioxide)
20:1
5
represents the combined hydration and dissociation constants for CO2 in blood at 37°C
6.1
6
formula: Getting dissolved carbon dioxide (dCO,)
pCO2 x 0.03
7
associated with both metabolic and respiratory alkalosis
Hypokalemia
8
only anticoagulant that does not alter the pH of blood
Heparin
9
anticoagulant Open heart surgery
Heparin
10
anticoagulant For cardiopulmonary bypass
Heparin
11
Storage time for ABG should be no more than
30 min
12
exposure of a normal arterial blood sample to room air PO2 ?, PCO2 ?>, pH ?
PO2 increased PCO2 decreased pH increased
13
how many pH decrease/each Celsius above 37°C
.015
14
Inhibit GH secretion (6)
BI GATE B-agonist (epinephrine) Insulin def Glucose loading a-blockers (phentolamine) Thyroxine def Emotional/Psychogenic stress
15
Gold standard for GH deficiency
Insulin Tolerance Test
16
Confirmatory for acromegaly
GLUCOSE SUPPRESSION TEST (OGTT 100g glucose)
17
Not a hormone-producing-gland
Posterior pituitary gland
18
Secretes Oxytocin and ADH
Posterior pituitary gland
19
Milk ejection and uterine contraction
Oxytocin
20
Water retention
ADH
21
Low ADH/ADH resistant — Diabetes insipidus
ADH
22
High ADH — SIADH
ADH
23
Thyroid location
Lower anterior neck
24
Majority of T4 is bound to
TBG —a globulin
25
Most potent Thyroid hormone
T3
26
Predominant Thyroid hormone
T4
27
Test used to Differentiate Primary from secondary Hypothyroidism
TSH Test
28
If a screening TSH is high, which test is likely to be ordered next?
FT4
29
the most reliable indicator of thyroid status in sick individuals
FT4
30
Increase protein will
increase TBG
31
Antithyroglobulin autoantibodies — interference . what assay?
TG- Thyroglobulin assay
32
Not a part of thyroid function test
TG assay
33
the MOST POTENT mineral corticoid (electro-regulating hormone)
Aldosterone
34
this Increase in BP and BV (Blood volume) suppresses secretion of renin
Aldosterone
35
Confirmatory test for Conn/primary hyperaldosteronism
Saline suppression test
36
specimen: The most sensitive and specific screening test for excess cortisol prod using HPLC or GC-MS
24 hr urine free cortisol
37
MOST WIDELY USED salivary cortisol test
Overnight/rapid dexamethasone suppression test
38
The most sensitive and specific screening test for excess cortisol prod
Low Dose dexamethasone Suppression test
39
spx MOST WIDELY USED salivary cortisol test
Midnight plasma cortisol
40
GOLD STANDARD for secondary and tertiary hypocortisolism
Insulin Tolerance Test (ITT)
41
First responders to stress
Cathecholamines
42
Major metabolite of epinephrine
VMA
43
Major metabolite of Dopamine
HVA
44
has poor sensitivity and specificity (least helpful) in the diagnosis of pheochromocytoma
Urinary VMA
45
Urinary VMA has poor sensitivity and specificity (least helpful) in the diagnosis of
pheochromocytoma
46
Cardioprotective > assoc to CVD
Estrogens
47
Present in both male and female
Estradiol (E2)
48
SINGLE BEST HORMONE to determine whether OVULATION HAS OCCURRED
Progesterone
49
causes infertility
Stress
50
Stress causes
infertility
51
diagnostic marker for Zollinger-Ellison Syndrome
Gastrin
52
Gastrin diagnostic marker for
Zollinger-Ellison Syndrome
53
Diagnostic marker for Carcinoid syndrome. (Argentaffinoma)
5HIAA
54
5HIAA Diagnostic marker for
Carcinoid syndrome. (Argentaffinoma)
55
Vitamin K (phylloquinone )deficiency
Hemorrhage
56
? deficiency Hemorrhage
Vitamin K (phylloquinone )deficiency
57
Vitamin B6 deficiency
Facial seborrhea
58
deficiency Facial seborrhea
Vitamin B6 deficiency
59
Vit C deficiency
Scurvy
60
deficiency Scurvy
Vit C deficiency
61
it is the highest concentration of a drug obtained in the dosing interval
Peak concentration
62
the lowest concentration of a drug obtained in the dosing interval
Trough Concentration
63
is the specimen of choice for the determination of circulating concentrations of most drugs
Serum or plasma
64
SPX is suitable for most drug analysis
Heparinized plasma
65
Anticoagulant of Choice for TDM
Sodium fluoride
66
the release of drug
Liberation
67
transport of drug to the blood
.Absorption
68
delivery of drug to the tissues ($.2019)
Distribution
69
what do you call the chemical modification of drug by cells
Metabolism
70
limination of drug or its metabolite
Excretion
71
Treatment for Congestive heart failure
Digoxin
72
are Nephrotoxic and ototoxic
Aminoglycosides
73
Red man syndrome
Vancomycin
74
Drug most often implicated in acquired aplastic anemia
Chloramphenicol
75
for grand mal seizures
Carbamazepine (Tegretol)
76
Drug of Choice for controlling Petit mal
Ethosuximide (Zarontin)
77
treatment of manic-depressive illness (bipolar disorder)
Lithium
78
Antiasthmatic
Theophylline Theobromine
79
Theophylline Theobromine IS FOR?
Anti asthmatic
80
Analgesics EXAMPLES
ISAAAT Ibuprofen Salicylates/Aspirin/ acetylsalicylic acid Acetaminophen (Tylenol)
81
antibiotic which Inhibit cyclooxygenase
Aspirin
82
antibiotic Assoc to Reye’s syndrome
Aspirin
83
Most trace elements are of medical importance because excessive levels lead to
toxicity
84
Trace no known biological purpose
ME THA L CA A MErcury, THAllium, Lead, CAdmium, and Aluminum
85
elements that Has known biologic purpose
Arsenic zinc, and copper
86
- necessary for normal methionine metabolism selenium, (m.23)
Arsenic
87
as the detector - reference method for quantitative identification of most organic compounds
gas chromatography coupled with a mass spectrometer (GC-MS)
88
is formed when yeast ferments sugar
Alcohol
89
Most common abused drug
Ethanol
90
ratio of >2 is highly specific for ethanol-related liver disease
AST/ALT
91
AST/ALT —a ratio of >2 is highly specific for ethanol-related to what dse?
liver disease
92
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.01-0.05 " Stage of Alcohol Influence ?
Subclinical
93
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.03-0.12 " Stage of Alcohol Influence ?
Euphoria
94
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.09-0.25 " Stage of Alcohol Influence ?
Excitement
95
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.18-0.30 " Stage of Alcohol Influence ?
Confusion
96
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.25-0.40 " Stage of Alcohol Influence ?
Stupor
97
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.35-0.50 " Stage of Alcohol Influence ?
Coma
98
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) "0.45+ " Stage of Alcohol Influence ?
Death
99
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) ? Stage of Alcohol Influence "Subclinical "
0.01-0.05
100
Stages of Acute Alcoholic Influence/Intoxication Blood alcohol concentration (g/100mL) ? Stage of Alcohol Influence "Euphoria "
0.03-0.12