mitotane causes selective destruction of normal and neoplastic adrenal cortical cells by inhibiting production of steroids induced by adrenocorticotropic hormone, which causes atrophy of the inner zones of the adrenal cortex. it is a derivative of:

among the ff acids, which can be used as spermatocide

a dosing regimen of an antimicrobial is based on:

this is a nicotinic anthelmintic that acts as agonist at nicotinic acetylcholine receptors of nematodes

lincosamide is contraindicated in this animal

these antiviral drugs inhibit viral nucleic acid synthesis

a systemic antifungal agent, this should not be used in pregnant animals because it is embryo toxic and teratogenic

which of the following is the most appropriate therapy for swine dysentery

which of the ff drug combination is not good

all of the ff are antineoplastic mitotic inhibitors except:

the canine tumor which is usually treated

this is the primary lesion of aminoglycoside toxicity in the kidney:

lugols solution is

what is the most notorious side effect of amphotericin B?

this is a semisynthetic glycosides derived from the mandrake plant. it is thought to stimulate DNA cleavage mediated by topo isomerase II which contributes to its antineoplastic action

these are naturally derived pesticides from chrysanthemum flower

which of the following antiseptics can be incorporated in soaps, shampoos, ointments, and surgical scrubs because of its low potential for systemic and dermal toxicity?

this agent is used as growth promoter in pigs, but is now banned for use in food animals because of carcinogenic effect

all of the following are members of the 3rd generation quinolones EXCEPT

in cattle, this drug at present is most effective against coccidiosis

this is observed when two or more bacteriostatic antibacterial agents are used in combination

a way of bacteria acquiring resistance through the passage of resistant genes from cell to cell by direct contact through sex pilus or bridge

this is generallythe most active of the aminoglycosides which is a fermantation product of Micromonospora purpurea. this is often the aminoglycoside of choice for serious g- infections caused by susceptible organisms

which of the following agents would be most effective in treating demotectic mange?

allergies due to penicillin is brought about by:

penicillins are the most active during which phase of bacterial growth

aside from being a dewormer, this agent also has antifungal property

this dewormer act by binding to glutamate gated chloride channel receptors in nematode and arthropod nerve cells allowing an influx of chloride ions:

this is a group of antineoplastic drugs that form highly reactive intermediate compounds that are able to transfer alkyl group to DNA

this saltor pyrantel makes it poorly soluble in water, thus allowing the drug to reach and be effective against parasite in the large intestines:

in cattle, this anthelmintic is 100% effective against all GIT roundworms except nematodirus ostertagia and trichuris

an antiviral that lead to inhibition or delay of the uncoating process that preceds primary transcription

this physical method or microbial control applies pressure to boiling water to prevent steam from escaping

ivermectin is contraindicated in this breed of dog because of idiosyncratic reactions which include depression, muscle weakness, blindness, come and death

benzalkonium chloride is a :

the most important advantage of potentiated sulfonamides over regular sulfonamide is

although it has no effects in roundworms and tapeworms, this benzimidazole has high activity against all stages of liver flukes

an azole antibiotic, this agent is used to treat Candida vaginitis in humasn and it is 1% solution is the drug of choice for Aspergillus infections of the comea

cotrimoxazole is a potentiated sulfonamide which consist of trimethoprim and:

this is a major adverse effect od griseofulvin

all of the following are members of the 3rd generation of quinolones EXCEPT:

this probenzimidazole is a metabolized to true benzimidazole but has teratogenic effects in sheep due to its oxfendazole metabolite

rubbing alcohol is simply:

melarsomine is:

this drug is characterized by cardiac toxicity (tachycardia and decreased contractility

heartgard ® contains ivermectin which:

repeated exposure of skin to high concentrations of this agent may lead to sufficient absorption of the antiseptic to cause nervous disorders

Tylosin is used primarily in the poultry as feed additive. it is included under this family of bacteriostatic antibacterial

which of the following combinations is considered irrational or antagonistic systematically

which of the following agents is not an inhibitor of DNA synthesis and replication

the antineoplastic drug taxanes are extracted from what plant?

he is considered as the father of chemotherapy

this is a purine nucleoside:

sulbactam and clavulanic acid are combined with amoxicillin to:

which of the following antineoplastic agents must be activated in the liver to cytotoxic metabolites?

in a combination of sulfonamides, as in triple sulfa, the solubility of in water of each sulfonamide

all of the following are used for treatment of malaria except

all of these are antibacterial that inhibits nucleic acid function EXCEPT

this is a viscid blackish brown liquid, used primarily for antiseptic bandaging of wounds of the hoof and horn:

this oxidizing agent has keratolytic and anti seborrheic activity which makes it useful in treating pyoderma in dogs

moxalactam is a:

vincristine is an alkaloid product of this plant?

this agent is unique among the anthelmintics because it heightens endogenous GABA induced inhibitory actions in worms to cause paralysis

which is NOT true about penicillins?

which of the following agents is a pyrimidine nucleoside

a systemic antiviral agent, this is active against all herpesviruses and it is more active than acyclovir against cytomegalovirus for instance in a bone marrow transplant recipient

which of the ff agents serve as an ideal teat dip?

this agent is combined with pyrethroids (including citrus extracts) to act synergistically in the prevention of metabolic inactivation of the pyrethroid within the insect

what is the active ingredient of zonrox®?

a third generation cephalosporin which has a gram negative spectrum that is more similar to the fist generation cephalosporin

this is the sulfonamide which is commonly used against urinary tract infection

this systemic antiviral agent is used to treat influenza, bovine herpesvirus, canine distemper, blue tongue, Mareks disease and rotavirus

what is the mechanismof action of macrolides?

a polyene antibiotic, this is the first antimycotic antibiotic to be discovered which has a fairly broad spectrum of activity against yeast and various fungi

which of the ff is not a bacteriostatic drug?

tamiflu ®, which is against many flu strains is

due to its effects of causing aplastic anemia to humans, this antibacterial is now banned in food animals in the philippines

all of the following are bacteriocidal EXCEPT

among the ff agents, which can be used as an astringent?

colistin belongs to the antibiotic group called ___, whose bacterial effect is___

what is the mechanism of action of piperazine against helminths?

these are considered bacteriostatic by inhibiting the protein synthesis by reversibly binding to 30s ribosomal subunit.they were one of the first to be known as "broad spectrum" antibiotics

this refers to killing or removing all forms of microbial life (including endospores) in a metal or aj object

what organism produces chloramphenicol

the mechanism of action of griseofulvin

5-fluorouracil must be converted to an active 5-fluoro-2'-deoxyuridine-5'-phosphate form to bind the enzyme thymidylate synthase and block or inhibit DNA and RNA synthase. it is a:

neuromuscular blockade results because of this action of aminoglycosides:

diaveridine is a trimethoprim against this parasite:

macrolide antibiotics and their metabolites are excreted mainly in the:

which of the following is contraindicated when given simultaneously with tetracyclines

what was the source of the first sulfonamide?

an example of delayed toxicity that is seen in antiviral agents and the patient exhibits increased incidence of infection associated with leukopenia, increased risk of hemorrhage associated with thrombocytopenia and anemia

among the synthetic antiviral agents, this agent may inhibit replication of different strains of influenza A virus, influenza C virus, sendai virus and pseudorabies virus at usual concentration

this antifungal can lead to normocytic normochromic anemia

this is the choice of treatment for disseminated histoplasmosis in dogs and cats

this is the enzyme inhibited by trimethoprim

potassium permanganate as an effective algicide and virucide is classfied as

this substance can serve as a flase substrate for penicillinase therefore it can protect a penicillin antibiotic from destruction of penicillinase:

this antifungal has 100% bioavailability

nematode species that are resistant to ivermectin are also likely to be resistant to: